BR0014843A - Composto, composição farmacêutica, métodos para tratar ou prevenir o câncer em um mamìfero, uma doença em que a angiogênese está implicada, a vascularização retinal, a retinipatia diabética, a degeneração macular relacionada com a idade, doença inflamatória, uma doença ou condição dependente de tirosina quinase e, patologias relacionadas com o osso, processo para fabricar uma composição farmacêutica, e, método para reduzir ou impedir o dano de tecido que segue um evento isquêmico - Google Patents

Composto, composição farmacêutica, métodos para tratar ou prevenir o câncer em um mamìfero, uma doença em que a angiogênese está implicada, a vascularização retinal, a retinipatia diabética, a degeneração macular relacionada com a idade, doença inflamatória, uma doença ou condição dependente de tirosina quinase e, patologias relacionadas com o osso, processo para fabricar uma composição farmacêutica, e, método para reduzir ou impedir o dano de tecido que segue um evento isquêmico

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Publication number
BR0014843A
BR0014843A BR0014843-1A BR0014843A BR0014843A BR 0014843 A BR0014843 A BR 0014843A BR 0014843 A BR0014843 A BR 0014843A BR 0014843 A BR0014843 A BR 0014843A
Authority
BR
Brazil
Prior art keywords
disease
pharmaceutical composition
tyrosine kinase
angiogenesis
methods
Prior art date
Application number
BR0014843-1A
Other languages
English (en)
Inventor
Kenneth L Arrington
Mark T Bilodeau
Mark E Fraley
George D Hartman
William F Hoffman
Randall W Hungate
Yuntae Kim
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of BR0014843A publication Critical patent/BR0014843A/pt

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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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Abstract

"COMPOSTO, COMPOSIçãO FARMACêUTICA, MéTODOS PARA TRATAR OU PREVENIR O CâNCER EM UM MAMìFERO, UMA DOENçA EM QUE A ANGIOGêNESE ESTá IMPLICADA, A VASCULARIZAçãO RETINAL, A RETINIPATIA DIABéTICA, A DEGENERAçãO MACULAR RELACIONADA COM A IDADE, DOENçA INFLAMATóRIA, UMA DOENçA OU CONDIçãO DEPENDENTE DE TIROSINA QUINASE E, PATOLOGIAS RELACIONADAS COM O OSSO, PROCESSO PARA FABRICAR UMA COMPOSIçãO FARMACêTICA, E, MéTODO PARA REDUZIR OU IMPEDIR O DANO DE TECIDO QUE SEGUE UM EVENTO ISQUêMICO." A presente invenção diz respeito a compostos que inibem, regulam e/ou modulam a transdução de sinal da tirosina quinase, a composições que contenham estes compostos e a métodos de usá-los para tratar doenças e condições dependentes da tirosina quinase, tais como angiogênese, câncer, desenvolvimento de tumor, arteriosclerose, degeneração macular relacionada com a idade, retinopatia diabética, doença inflamatória e outras em mamíferos.
BR0014843-1A 1999-10-19 2000-10-16 Composto, composição farmacêutica, métodos para tratar ou prevenir o câncer em um mamìfero, uma doença em que a angiogênese está implicada, a vascularização retinal, a retinipatia diabética, a degeneração macular relacionada com a idade, doença inflamatória, uma doença ou condição dependente de tirosina quinase e, patologias relacionadas com o osso, processo para fabricar uma composição farmacêutica, e, método para reduzir ou impedir o dano de tecido que segue um evento isquêmico BR0014843A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16035699P 1999-10-19 1999-10-19
PCT/US2000/028625 WO2001029025A2 (en) 1999-10-19 2000-10-16 Tyrosine kinase inhibitors

Publications (1)

Publication Number Publication Date
BR0014843A true BR0014843A (pt) 2002-06-11

Family

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BR0014843-1A BR0014843A (pt) 1999-10-19 2000-10-16 Composto, composição farmacêutica, métodos para tratar ou prevenir o câncer em um mamìfero, uma doença em que a angiogênese está implicada, a vascularização retinal, a retinipatia diabética, a degeneração macular relacionada com a idade, doença inflamatória, uma doença ou condição dependente de tirosina quinase e, patologias relacionadas com o osso, processo para fabricar uma composição farmacêutica, e, método para reduzir ou impedir o dano de tecido que segue um evento isquêmico

Country Status (40)

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US (1) US6306874B1 (pt)
EP (1) EP1226136B1 (pt)
JP (2) JP3822494B2 (pt)
KR (1) KR100681724B1 (pt)
CN (1) CN1213045C (pt)
AR (1) AR035626A1 (pt)
AT (1) ATE286045T1 (pt)
AU (1) AU778588B2 (pt)
BG (1) BG65585B1 (pt)
BR (1) BR0014843A (pt)
CA (1) CA2387351C (pt)
CO (1) CO5261601A1 (pt)
CZ (1) CZ20021390A3 (pt)
DE (1) DE60017179T2 (pt)
DZ (1) DZ3223A1 (pt)
EA (1) EA005812B1 (pt)
EE (1) EE05107B1 (pt)
EG (1) EG24381A (pt)
ES (1) ES2234698T3 (pt)
GE (1) GEP20053530B (pt)
HK (1) HK1054931A1 (pt)
HR (1) HRP20020349A2 (pt)
HU (1) HUP0203323A3 (pt)
IL (2) IL148891A0 (pt)
IS (1) IS2165B (pt)
MX (1) MXPA02003887A (pt)
MY (1) MY137656A (pt)
NO (1) NO325696B1 (pt)
NZ (1) NZ518001A (pt)
PE (1) PE20010749A1 (pt)
PL (1) PL202842B1 (pt)
PT (1) PT1226136E (pt)
RS (1) RS50380B (pt)
SA (2) SA06270148B1 (pt)
SK (1) SK286628B6 (pt)
TR (1) TR200201051T2 (pt)
TW (1) TWI239957B (pt)
UA (1) UA74560C2 (pt)
WO (1) WO2001029025A2 (pt)
ZA (1) ZA200202985B (pt)

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