BR0008453A - Composição sinergìstica anti-tumoral - Google Patents

Composição sinergìstica anti-tumoral

Info

Publication number
BR0008453A
BR0008453A BR0008453-0A BR0008453A BR0008453A BR 0008453 A BR0008453 A BR 0008453A BR 0008453 A BR0008453 A BR 0008453A BR 0008453 A BR0008453 A BR 0008453A
Authority
BR
Brazil
Prior art keywords
tumor composition
treatment
synergistically
metansulfonyl
demethoxy
Prior art date
Application number
BR0008453-0A
Other languages
English (en)
Inventor
Cristina Geroni
Michele Caruso
Antonino Suarato
Marina Ripamonti
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of BR0008453A publication Critical patent/BR0008453A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/396—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having three-membered rings, e.g. aziridine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Abstract

"COMPOSIçãO SINERGìSTICA ANTI-TUMORAL". São fornecidos o uso combinado de 4-demetoxi-3'-deamino-3'-aziridinil-4'metansulfonil daunorubicina ou 4-demetoxi-N,N-bis(2-cloroetil)-4'-metansulfonil daunorubicina e de um inibidor de topoisomerase II anti-neoplásico no tratamento de tumores, assim como na prevenção ou tratamento de metástase ou no tratamento de tumores pela inibição da angiogênese.
BR0008453-0A 1999-02-25 2000-01-31 Composição sinergìstica anti-tumoral BR0008453A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9904387.9A GB9904387D0 (en) 1999-02-25 1999-02-25 Antitumour synergistic composition
PCT/EP2000/000745 WO2000050032A1 (en) 1999-02-25 2000-01-31 Antitumour synergistic composition

Publications (1)

Publication Number Publication Date
BR0008453A true BR0008453A (pt) 2002-01-29

Family

ID=10848514

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0008453-0A BR0008453A (pt) 1999-02-25 2000-01-31 Composição sinergìstica anti-tumoral

Country Status (18)

Country Link
EP (1) EP1165069B1 (pt)
JP (1) JP2002537333A (pt)
KR (1) KR20010102364A (pt)
CN (1) CN1155378C (pt)
AR (1) AR043082A1 (pt)
AT (1) ATE279190T1 (pt)
AU (1) AU773506B2 (pt)
BR (1) BR0008453A (pt)
CA (1) CA2361826A1 (pt)
DE (1) DE60014873T2 (pt)
ES (1) ES2230060T3 (pt)
GB (1) GB9904387D0 (pt)
HK (1) HK1044466A1 (pt)
MY (1) MY135985A (pt)
PT (1) PT1165069E (pt)
TW (1) TW518223B (pt)
WO (1) WO2000050032A1 (pt)
ZA (1) ZA200106209B (pt)

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Also Published As

Publication number Publication date
HK1044466A1 (zh) 2002-10-25
EP1165069A1 (en) 2002-01-02
DE60014873D1 (de) 2004-11-18
AR043082A1 (es) 2005-07-20
CA2361826A1 (en) 2000-08-31
ES2230060T3 (es) 2005-05-01
WO2000050032A1 (en) 2000-08-31
AU773506B2 (en) 2004-05-27
CN1341019A (zh) 2002-03-20
EP1165069B1 (en) 2004-10-13
KR20010102364A (ko) 2001-11-15
ATE279190T1 (de) 2004-10-15
MY135985A (en) 2008-07-31
PT1165069E (pt) 2005-01-31
GB9904387D0 (en) 1999-04-21
TW518223B (en) 2003-01-21
DE60014873T2 (de) 2006-02-02
ZA200106209B (en) 2002-07-29
CN1155378C (zh) 2004-06-30
JP2002537333A (ja) 2002-11-05
AU2545900A (en) 2000-09-14

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