BG108070A - Нови пиримидинови съединения - Google Patents

Нови пиримидинови съединения Download PDF

Info

Publication number: BG108070A
Authority: BG; Bulgaria
Prior art keywords: alkyl; ring; pyrimidine; compound; group
Prior art date: 2001-02-20

Application number

BG108070A

Other languages

Bulgarian (bg)

English (en)

Inventor

Stefan Berg

Sven Hellberg

Original Assignee

Astrazeneca AБ

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-02-20

Filing date

2003-08-07

Publication date

2004-07-30

2003-08-07 Application filed by Astrazeneca AБ filed Critical Astrazeneca AБ

2004-07-30 Publication of BG108070A publication Critical patent/BG108070A/bg

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Diabetes (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Virology (AREA)
Emergency Medicine (AREA)
Tropical Medicine & Parasitology (AREA)
Hospice & Palliative Care (AREA)
Oncology (AREA)
Obesity (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Hematology (AREA)
Dermatology (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
AIDS & HIV (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

BG108070A 2001-02-20 2003-08-07 Нови пиримидинови съединения BG108070A (bg)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE0100569A SE0100569D0 (sv)	2001-02-20	2001-02-20	New compounds
PCT/SE2002/000271 WO2002065979A2 (en)	2001-02-20	2002-02-18	(diazolo-pyridinyl)-pyrimidines for use in treatment of cns disorders and diabetes

Publications (1)

Publication Number	Publication Date
BG108070A true BG108070A (bg)	2004-07-30

Family

ID=20283059

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG108070A BG108070A (bg)	2001-02-20	2003-08-07	Нови пиримидинови съединения

Country Status (23)

Country	Link
US (1)	US7345050B2 (ja)
EP (1)	EP1373266A2 (ja)
JP (1)	JP4475869B2 (ja)
KR (1)	KR20030084935A (ja)
CN (1)	CN1294131C (ja)
BG (1)	BG108070A (ja)
BR (1)	BR0206935A (ja)
CA (1)	CA2434648A1 (ja)
CZ (1)	CZ20032235A3 (ja)
EE (1)	EE200300400A (ja)
HK (1)	HK1070071A1 (ja)
HU (1)	HUP0303254A2 (ja)
IL (1)	IL156781A0 (ja)
IS (1)	IS6868A (ja)
MX (1)	MXPA03007320A (ja)
NO (1)	NO20033679D0 (ja)
NZ (1)	NZ526783A (ja)
PL (1)	PL363393A1 (ja)
RU (1)	RU2003121307A (ja)
SE (1)	SE0100569D0 (ja)
SK (1)	SK10252003A3 (ja)
WO (1)	WO2002065979A2 (ja)
ZA (1)	ZA200306171B (ja)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0205693D0 (en)	2002-03-09	2002-04-24	Astrazeneca Ab	Chemical compounds
GB0205690D0 (en)	2002-03-09	2002-04-24	Astrazeneca Ab	Chemical compounds
AU2003208479A1 (en)	2002-03-09	2003-09-22	Astrazeneca Ab	4- imidazolyl substuited pyrimidine derivatives with cdk inhibitiory activity
GB0226583D0 (en) *	2002-11-14	2002-12-18	Cyclacel Ltd	Compounds
GB0311276D0 (en)	2003-05-16	2003-06-18	Astrazeneca Ab	Chemical compounds
GB0311274D0 (en)	2003-05-16	2003-06-18	Astrazeneca Ab	Chemical compounds
TW200528101A (en)	2004-02-03	2005-09-01	Astrazeneca Ab	Chemical compounds
US20080207594A1 (en)	2005-05-04	2008-08-28	Davelogen Aktiengesellschaft	Use of Gsk-3 Inhibitors for Preventing and Treating Pancreatic Autoimmune Disorders
EP1942897A1 (en) *	2005-10-03	2008-07-16	AstraZeneca AB	Use of pyrimidine derivatives in the manufacture of a medicament for prevention and/or treatment of alzheimer's disease
AR058073A1 (es) *	2005-10-03	2008-01-23	Astrazeneca Ab	Derivados de imidazol 5-il-pirimidina, procesos de obtencion, composiciones farmaceuticas y usos
CN102887891B (zh)	2005-11-15	2016-03-09	阿雷生物药品公司	N4-苯基-喹唑啉-4-胺衍生物和相关化合物
TW200811169A (en) *	2006-05-26	2008-03-01	Astrazeneca Ab	Chemical compounds
NZ578744A (en) *	2007-01-31	2012-02-24	Vertex Pharma	2-aminopyridine derivatives useful as kinase inhibitors
AR069501A1 (es)	2007-11-30	2010-01-27	Genentech Inc	Anticuerpos anti- vegf (factor de crecimiento endotelial vascular)
ES2524259T3 (es) *	2008-03-24	2014-12-04	Novartis Ag	Inhibidores de metaloproteinasa de matriz a base de arilsulfonamida
WO2010009139A2 (en)	2008-07-14	2010-01-21	Gilead Colorado, Inc.	Imidazolyl pyrimidine inhibitor compounds
AU2009271019A1 (en)	2008-07-14	2010-01-21	Gilead Sciences, Inc.	Fused heterocyclyc inhibitors of histone deacetylase and/or cyclin-dependent kinases
US8344018B2 (en)	2008-07-14	2013-01-01	Gilead Sciences, Inc.	Oxindolyl inhibitor compounds
MX2011001090A (es)	2008-07-28	2011-03-15	Gilead Sciences Inc	Compuestos de inhibidor de desacetilasa de histona de cicloalquilideno y heterocicloalquilideno.
MX2011004306A (es)	2008-10-22	2011-07-28	Genentech Inc	Modulacion de degeneracion de axones.
JP2012524063A (ja)	2009-04-15	2012-10-11	アストラゼネカ・アクチエボラーグ	アルツハイマー病などのグリコーゲンシンターゼキナーゼ３関連障害の治療に有用なイミダゾール置換ピリミジン
MX2011013166A (es)	2009-06-08	2012-01-30	Gilead Sciences Inc	Compuestos inhibidores de hdac de cicloalquilcarbamatobenzamida-an ilina.
EP2440519A1 (en)	2009-06-08	2012-04-18	Gilead Sciences, Inc.	Alkanoylamino benzamide aniline hdac inihibitor compounds
KR102414221B1 (ko)	2020-08-04	2022-06-27	서울시립대학교 산학협력단	열전 소자 어셈블리, 이의 제조 방법, 및 이를 포함하는 열전 모듈

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
USRE29032E (en) *	1969-06-12	1976-11-09	Riker Laboratories, Inc.	3-Benzoylfluoro-methanesulfonanilides
FR2179493A1 (en) *	1972-04-10	1973-11-23	Roussel Uclaf	Amino benzhydrols - choleretics anticonvulsants sedatives and barbiturate potentiators
DE3042466A1 (de) *	1980-11-11	1982-06-16	A. Nattermann & Cie GmbH, 5000 Köln	N-substituierte (omega) -(2-oxo-4-imidazolin-l-yl)-alkansaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
TW225528B (ja) *	1992-04-03	1994-06-21	Ciba Geigy Ag
US5521184A (en) *	1992-04-03	1996-05-28	Ciba-Geigy Corporation	Pyrimidine derivatives and processes for the preparation thereof
GB9523675D0 (en) *	1995-11-20	1996-01-24	Celltech Therapeutics Ltd	Chemical compounds
GB9701453D0 (en) *	1997-01-24	1997-03-12	Leo Pharm Prod Ltd	Aminobenzophenones
GB9919778D0 (en)	1999-08-21	1999-10-27	Zeneca Ltd	Chemical compounds

2001
- 2001-02-20 SE SE0100569A patent/SE0100569D0/xx unknown
2002
- 2002-02-18 MX MXPA03007320A patent/MXPA03007320A/es unknown
- 2002-02-18 JP JP2002565540A patent/JP4475869B2/ja not_active Expired - Lifetime
- 2002-02-18 BR BR0206935-0A patent/BR0206935A/pt not_active IP Right Cessation
- 2002-02-18 HU HU0303254A patent/HUP0303254A2/hu unknown
- 2002-02-18 CZ CZ20032235A patent/CZ20032235A3/cs unknown
- 2002-02-18 US US10/468,604 patent/US7345050B2/en not_active Expired - Fee Related
- 2002-02-18 WO PCT/SE2002/000271 patent/WO2002065979A2/en active IP Right Grant
- 2002-02-18 CN CNB028052471A patent/CN1294131C/zh not_active Expired - Fee Related
- 2002-02-18 SK SK1025-2003A patent/SK10252003A3/sk unknown
- 2002-02-18 NZ NZ526783A patent/NZ526783A/en unknown
- 2002-02-18 RU RU2003121307/04A patent/RU2003121307A/ru not_active Application Discontinuation
- 2002-02-18 EE EEP200300400A patent/EE200300400A/xx unknown
- 2002-02-18 EP EP02711620A patent/EP1373266A2/en not_active Withdrawn
- 2002-02-18 PL PL02363393A patent/PL363393A1/xx not_active Application Discontinuation
- 2002-02-18 KR KR10-2003-7010874A patent/KR20030084935A/ko not_active Application Discontinuation
- 2002-02-18 CA CA002434648A patent/CA2434648A1/en not_active Abandoned
- 2002-02-18 IL IL15678102A patent/IL156781A0/xx unknown
2003
- 2003-07-08 IS IS6868A patent/IS6868A/is unknown
- 2003-08-07 BG BG108070A patent/BG108070A/bg unknown
- 2003-08-08 ZA ZA200306171A patent/ZA200306171B/xx unknown
- 2003-08-19 NO NO20033679A patent/NO20033679D0/no unknown
2005
- 2005-04-06 HK HK05102865A patent/HK1070071A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
CZ20032235A3 (cs)	2004-01-14
US20040077642A1 (en)	2004-04-22
MXPA03007320A (es)	2003-12-04
US7345050B2 (en)	2008-03-18
IS6868A (is)	2003-07-08
HK1070071A1 (en)	2005-06-10
EP1373266A2 (en)	2004-01-02
PL363393A1 (en)	2004-11-15
IL156781A0 (en)	2004-02-08
CA2434648A1 (en)	2002-08-29
NZ526783A (en)	2005-04-29
HUP0303254A2 (hu)	2004-01-28
SK10252003A3 (sk)	2004-02-03
BR0206935A (pt)	2004-06-29
SE0100569D0 (sv)	2001-02-20
NO20033679L (no)	2003-08-19
JP2004527486A (ja)	2004-09-09
ZA200306171B (en)	2004-11-08
EE200300400A (et)	2003-12-15
NO20033679D0 (no)	2003-08-19
CN1537112A (zh)	2004-10-13
WO2002065979A2 (en)	2002-08-29
CN1294131C (zh)	2007-01-10
WO2002065979A3 (en)	2003-02-20
RU2003121307A (ru)	2005-02-27
KR20030084935A (ko)	2003-11-01
JP4475869B2 (ja)	2010-06-09

Publication	Publication Date	Title
BG108070A (bg)	2004-07-30	Нови пиримидинови съединения
KR101110457B1 (ko)	2012-02-17	Ｇｓｋ3에서 선택적 저해 효과를 갖는 신규 화합물
JP4309657B2 (ja)	2009-08-05	Ｇｓｋ−３関連障害の治療のための２−アリルアミノ−ピリミジン
JP4465188B2 (ja)	2010-05-19	新規な化合物
JP3989444B2 (ja)	2007-10-10	新規な化合物
US20090018130A1 (en)	2009-01-15	Derivatives of 5-Aryl-1H-Pyrrolo [2, 3B] Pyridine-3-Carboxamide or 5-Aryl-1H-Pyrrolo [2, 3B] Pyridine-3-Carboxylic Acid
CA2878435C (en)	2020-08-25	Benzisoxazole modulators of neurogenesis
AU2002230365A1 (en)	2002-09-04	(Diazolo-pyridinyl)-pyrimidines for use in treatment of CNS disorders and diabetes
AU2002232346A1 (en)	2002-09-04	2-arylamino-pyrimidines for the treatment of GSK3-related disorders