BE783449A - Perfectionnements relatifs aux antibiotiques - Google Patents

Perfectionnements relatifs aux antibiotiques

Info

Publication number
BE783449A
BE783449A BE783449A BE783449A BE783449A BE 783449 A BE783449 A BE 783449A BE 783449 A BE783449 A BE 783449A BE 783449 A BE783449 A BE 783449A BE 783449 A BE783449 A BE 783449A
Authority
BE
Belgium
Prior art keywords
antibiotics
improvements related
Prior art date
Application number
BE783449A
Other languages
English (en)
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26251025&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BE783449(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of BE783449A publication Critical patent/BE783449A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/42—Singly bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/14—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BE783449A 1971-05-14 1972-05-12 Perfectionnements relatifs aux antibiotiques BE783449A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1508271A GB1399086A (en) 1971-05-14 1971-05-14 Cephalosporin compounds
GB4588471 1971-10-01

Publications (1)

Publication Number Publication Date
BE783449A true BE783449A (fr) 1972-11-13

Family

ID=26251025

Family Applications (1)

Application Number Title Priority Date Filing Date
BE783449A BE783449A (fr) 1971-05-14 1972-05-12 Perfectionnements relatifs aux antibiotiques

Country Status (22)

Country Link
JP (3) JPS531280B1 (fr)
AT (1) AT336786B (fr)
BE (1) BE783449A (fr)
CA (1) CA1027554A (fr)
CH (1) CH591497A5 (fr)
CS (2) CS245753B2 (fr)
CY (1) CY971A (fr)
DE (2) DE2265234C2 (fr)
DK (1) DK155187C (fr)
ES (2) ES402651A1 (fr)
FR (2) FR2137900B1 (fr)
GB (1) GB1399086A (fr)
HK (1) HK66078A (fr)
IE (1) IE38172B1 (fr)
IL (1) IL39429A (fr)
KE (1) KE2895A (fr)
MY (1) MY7800466A (fr)
NL (1) NL166688C (fr)
NO (1) NO154797C (fr)
PH (1) PH11205A (fr)
SE (1) SE457795B (fr)
YU (2) YU41807B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000053609A1 (fr) * 1999-03-09 2000-09-14 Ranbaxy Laboratories Limited Procede de preparation de cefuroxime

Families Citing this family (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4033950A (en) * 1971-05-14 1977-07-05 Glaxo Laboratories Limited 3-Hydroxymethyl-7β-(2-alkoxy-or benzyloxyimino-2-arylacetamido)ceph-3-em-4-carboxylic acids and salts thereof
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
US4079178A (en) * 1971-05-14 1978-03-14 Glaxo Laboratories Limited Cephalosporins having (α-etherified oximino) acylamido groups at the 7-position
GB1445979A (en) * 1972-10-25 1976-08-11 Glaxo Lab Ltd Cephalosporin derivatives
US4138555A (en) 1971-05-14 1979-02-06 Glaxo Laboratories, Limited (6R,7R)-7-[2-aryl-2-(etherified oximino)acetamido]-3-carbamoyloxymethylceph-3-em-4-carboxylic acid 1-oxides
US4064346A (en) * 1971-05-14 1977-12-20 Glaxo Laboratories Limited 3-Acetoxymethyl-7β-(2-carboxy-methoxyimino-2-arylacetamido)ceph-3-em-4-carboxylic acids and salts thereof
AR208283A1 (es) * 1973-03-15 1976-12-20 Fujisawa Pharmaceutical Co Un procedimiento para la preparacion de derivados de acido 2-alquil-2-o 3-fefem-4-carboxilico
HU172234B (hu) * 1973-12-21 1978-07-28 Glaxo Lab Ltd Sposob poluchenija novykh proizvodnykh 7-beta-acilamido-cef-3-em-4-karbonovojj kisloty
US4095021A (en) 1973-12-21 1978-06-13 Glaxo Laboratories Limited 3-Carbamoyloxymethyl or N-methyl-carbamoyloxymethyl-7-[2-carboxymethoxyimino-2-(fur-2-yl or thien-2-yl)acetamido]ceph-3-em-4-carboxylic acids and derivatives thereof
US4144392A (en) 1973-12-21 1979-03-13 Glaxo Laboratories Limited Cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyimino-arylacetamido group and at position-3 the residue of a sulphur nucleophile
GB1512957A (en) * 1974-08-23 1978-06-01 Glaxo Lab Ltd Gephalosporin antibiotics
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
US4200746A (en) 1974-12-20 1980-04-29 Glaxo Laboratories, Ltd. Cephalosporins
GB1522140A (en) * 1974-12-20 1978-08-23 Glaxo Lab Ltd Syn-7-(2-hydroxyiminoacetamido)-3-pyridiniummethyl cephalosporins methods for their preparation and compositions containing them
PH15487A (en) * 1975-02-04 1983-01-31 Fujisawa Pharmaceutical Co 7((2-hydroxyamino-2-disubstituted phenyl-acetamido)-)3-heterocyclithio-3-cephem-4-carboxylic acids
GB1555471A (en) * 1975-06-19 1979-11-14 Glaxo Lab Ltd 7 carbamoylalkoxyimino acetamido 3 em 4 carboxylic acidsand derivatives thereof
SE440655B (sv) * 1976-01-23 1985-08-12 Roussel Uclaf Sett att framstella nya oximderivat av 7-amino-tiazolyl-acetamido-cefalosporansyra
DE2760123C2 (de) 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
IE44888B1 (en) * 1976-03-09 1982-05-05 Fujisawa Pharmaceutical Co 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation theroef
GB1575803A (en) 1976-03-09 1980-10-01 Fujisawa Pharmaceutical Co 3,7 disubstituted 3 cephem 4 carboxylic acid compounds andprocesses for the preparation thereof
US4165430A (en) 1976-03-19 1979-08-21 Glaxo Laboratories Limited Cephalosporins having a 7-carboxy substituted α-etherified oximinoarylacetamido) group
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
DE2715385A1 (de) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
US4066762A (en) * 1976-07-12 1978-01-03 Smithkline Corporation Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid
US4278670A (en) * 1976-07-12 1981-07-14 Smithkline Corporation 7-Alpha-oxyiminoacylcephalosporins
FR2361895A1 (fr) * 1976-08-20 1978-03-17 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-carbamoyloxymethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
GB1592149A (en) * 1976-10-08 1981-07-01 Fujisawa Pharmaceutical Co 3 7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for preparation thereof
FR2381053A1 (fr) * 1977-02-18 1978-09-15 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
JPS53103493A (en) * 1977-02-18 1978-09-08 Takeda Chem Ind Ltd Cephalosporin derivatives and process for their preparation
PH17188A (en) 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
FR2384779A1 (fr) * 1977-03-25 1978-10-20 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-chloro ou 3-methoxy 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
SE439312B (sv) * 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
DE2716677C2 (de) 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
NL7805715A (nl) * 1977-06-03 1978-12-05 Hoffmann La Roche Werkwijze voor het bereiden van acylderivaten.
IT1192287B (it) * 1977-11-14 1988-03-31 Fujisawa Pharmaceutical Co Derivati di acido cefalosporanico ad azione farmaceutica e relativo procedimento di preparazione
FR2438051A2 (fr) * 1978-10-05 1980-04-30 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-azidomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
SE445350B (sv) * 1978-04-14 1986-06-16 Roussel Uclaf Oximderivat av 3-azidometyl-7-amino-tiazolyl-acetamido-cefalosporansyra och dess anvendning som antibiotika
DE2822860A1 (de) * 1978-05-26 1979-11-29 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
AR229883A1 (es) 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
DE2822861A1 (de) * 1978-05-26 1979-11-29 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
US4268509A (en) * 1978-07-10 1981-05-19 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
ES485938A1 (es) * 1978-11-15 1980-07-01 Glaxo Group Ltd Un procedimiento para la preparacion de antibioticos de ce- falosporina
DE2914327A1 (de) * 1979-04-09 1980-10-30 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
EP0088454B1 (fr) * 1979-09-03 1986-03-05 Fujisawa Pharmaceutical Co., Ltd. Produits de départ pour préparer des dérivés de céphalosporines et procédés pour les préparer
US4341777A (en) * 1979-09-10 1982-07-27 Glaxo Group Limited Cephalosporin antibiotic
EP0027599B1 (fr) * 1979-10-12 1984-10-03 Fujisawa Pharmaceutical Co., Ltd. Dérivés de céphalosporine, leur préparation et compositions pharmaceutiques les contenant
EP0104671B1 (fr) * 1980-02-18 1990-05-23 Roussel-Uclaf Nouvelles oximes dérivées de l'acide 3-alkyloxy ou 3-alkylthiométhyl-7 amino thiazolylacétamido céphalosporaniques, leur préparation, leur application comme médicaments et les compositions les renfermant
FR2476087A1 (fr) * 1980-02-18 1981-08-21 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkyl-thiomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
EP0037797A3 (fr) * 1980-03-11 1981-12-16 Ciba-Geigy Ag Dérivés de céphalosporine, procédés de préparation, compositions pharmaceutiques les contenant et leur application
ZA813787B (en) * 1980-06-18 1982-07-28 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
GR75644B (fr) * 1980-06-18 1984-08-02 Fujisawa Pharmaceutical Co
IL63207A (en) * 1980-07-24 1985-09-29 Lonza Ag Process for the preparation of 2-(2-aminothiazole-4-yl)-2-(syn)-methoxyiminoacetic acid esters
US4443444A (en) * 1980-08-11 1984-04-17 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
EP0156118A1 (fr) * 1980-08-29 1985-10-02 Fujisawa Pharmaceutical Co., Ltd. Produits de départ pour la préparation de composés céphem et procédés pour leur préparation
US4416879A (en) * 1980-09-08 1983-11-22 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
NZ198350A (en) * 1980-09-25 1985-02-28 Toyama Chemical Co Ltd Cephalosporins and intermediates;pharmaceutical compositions
IL63965A (en) * 1980-10-10 1985-01-31 Sparamedica Ag 7-(2-(2-amino-4-selenazoyl)acetamido)cephalosporin derivatives,and intermediates therefor,their preparation and pharmaceutical compositions containing them
FR2494274A2 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouvelles thiovinyl-3 cephalosporines, leur preparation et les medicaments qui les contiennent
FR2494279A1 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouvelles oxacephalosporines, leur preparation et les medicaments qui les contiennent
FR2494280A1 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouveaux derives de la cephalosporine et leur preparation
FR2494276A2 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouvelles vinyl-3 cephalosporines, et leur preparation
FR2494275A2 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouveaux derives de vinyl-3 cephalosporines et leur preparation
GR76342B (fr) * 1981-02-02 1984-08-06 Fujisawa Pharmaceutical Co
FR2499995A1 (fr) * 1981-02-13 1982-08-20 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkylthiomethyl 7-amino thiazolylacetamido cephalosporanique, leur preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
JPS6011917B2 (ja) * 1981-04-09 1985-03-28 山之内製薬株式会社 新規なセファロスポリン化合物
FR2505338A1 (fr) * 1981-05-11 1982-11-12 Rhone Poulenc Sante Nouvelles oxacephalosporines et leur preparation
FR2505339A1 (fr) * 1981-05-11 1982-11-12 Rhone Poulenc Sante Nouvelles oxacephalosporines et leur preparation
EP0070803A3 (fr) * 1981-07-16 1984-05-02 Ciba-Geigy Ag Dérivés d'aminotriazolylcéphalosporine antibiotiques et leur préparation
GR76701B (fr) * 1981-09-08 1984-08-29 Lilly Co Eli
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
JPS5859992A (ja) * 1981-09-14 1983-04-09 Fujisawa Pharmaceut Co Ltd 新規セフエム化合物およびその製造法、並びに細菌感染症予防・治療剤
MA19602A1 (fr) * 1981-09-30 1983-04-01 Ciba Geigy Ag Composes d'amino-oxazolyle, procede pour leur preparation, preparations pharmaceutiques qui contiennent ces composes, et leur application
US4401668A (en) * 1981-10-02 1983-08-30 Eli Lilly And Company Pyrazinium substituted cephalosporins
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US4394503A (en) 1981-12-07 1983-07-19 Bristol-Myers Company Cephalosporin derivatives
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DK155187B (da) 1989-02-27
SE457795B (sv) 1989-01-30
ES402651A1 (es) 1975-11-01
DE2223375A1 (de) 1972-11-23
JPS6324993B2 (fr) 1988-05-23
IL39429A (en) 1978-04-30
FR2137900A1 (fr) 1972-12-29
GB1399086A (en) 1975-06-25
ES430104A1 (es) 1976-10-01
YU41807B (en) 1988-02-29
NL166688C (nl) 1985-01-16
DE2265234C2 (de) 1983-02-10
NO154797C (no) 1986-12-29
CY971A (en) 1978-12-22
FR2137899A1 (fr) 1972-12-29
DK155187C (da) 1989-07-17
YU321379A (en) 1982-02-28
CS245754B2 (en) 1986-10-16
KE2895A (en) 1978-11-10
YU126772A (en) 1982-02-28
NL7206403A (fr) 1972-11-16
CA1027554A (fr) 1978-03-07
JPS54135792A (en) 1979-10-22
NO154797B (no) 1986-09-15
HK66078A (en) 1978-11-24
DE2223375C2 (de) 1985-05-15
NL166688B (nl) 1981-04-15
IL39429A0 (en) 1972-07-26
CH591497A5 (fr) 1977-09-30
MY7800466A (en) 1978-12-31
IE38172B1 (en) 1978-01-18
PH11205A (en) 1977-10-28
CS245753B2 (en) 1986-10-16
FR2137899B1 (fr) 1976-08-20
JPS531280B1 (fr) 1978-01-17
IE38172L (en) 1972-11-14
AT336786B (de) 1977-05-25
DE2265234A1 (de) 1976-12-30
ATA420872A (de) 1976-09-15
JPS5328141A (en) 1978-03-16
FR2137900B1 (fr) 1976-04-16

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