ATE99543T1 - Pulverfoermige zubereitungen zur intranasalen verabreichung von polypeptiden. - Google Patents

Pulverfoermige zubereitungen zur intranasalen verabreichung von polypeptiden.

Info

Publication number
ATE99543T1
ATE99543T1 AT88117029T AT88117029T ATE99543T1 AT E99543 T1 ATE99543 T1 AT E99543T1 AT 88117029 T AT88117029 T AT 88117029T AT 88117029 T AT88117029 T AT 88117029T AT E99543 T1 ATE99543 T1 AT E99543T1
Authority
AT
Austria
Prior art keywords
polypeptides
intranasal administration
powdered preparations
biologically active
powdered
Prior art date
Application number
AT88117029T
Other languages
English (en)
Inventor
Brian H Vickery
Cherng-Chyi Fu
Eric J Benjamin
Lynda M Sanders
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Application granted granted Critical
Publication of ATE99543T1 publication Critical patent/ATE99543T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Otolaryngology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
AT88117029T 1987-10-15 1988-10-13 Pulverfoermige zubereitungen zur intranasalen verabreichung von polypeptiden. ATE99543T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10967887A 1987-10-15 1987-10-15
EP88117029A EP0312052B1 (de) 1987-10-15 1988-10-13 Pulverförmige Zubereitungen zur intranasalen Verabreichung von Polypeptiden

Publications (1)

Publication Number Publication Date
ATE99543T1 true ATE99543T1 (de) 1994-01-15

Family

ID=22328950

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88117029T ATE99543T1 (de) 1987-10-15 1988-10-13 Pulverfoermige zubereitungen zur intranasalen verabreichung von polypeptiden.

Country Status (11)

Country Link
US (3) US6521597B1 (de)
EP (1) EP0312052B1 (de)
JP (1) JP2851627B2 (de)
KR (1) KR890006252A (de)
AT (1) ATE99543T1 (de)
AU (1) AU623609B2 (de)
CA (1) CA1336401C (de)
DE (1) DE3886880T2 (de)
ES (1) ES2061591T3 (de)
NZ (1) NZ226557A (de)
ZA (1) ZA887658B (de)

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AU758679B2 (en) 1998-07-24 2003-03-27 Seo Hong Yoo Preparation of aqueous clear solution dosage forms with bile acids
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US20050014681A1 (en) * 2001-11-26 2005-01-20 Yoshiharu Minamitake Medicinal compositions for nasal absorption
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CN1758930B (zh) 2003-03-27 2010-06-09 株式会社新日本科学 鼻腔用粉末药剂喷药装置
US7145125B2 (en) 2003-06-23 2006-12-05 Advanced Optical Technologies, Llc Integrating chamber cone light using LED sources
BRPI0507169A (pt) * 2004-02-02 2007-06-26 Ambrx Inc polipeptìdeos do hormÈnio de crescimento humano modificados e seu usos
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EP1869082B1 (de) * 2005-03-04 2011-04-13 The Board Of Trustees Of The University Of Illinois Modulator von coagulationskaskaden und fibrinolytischen kaskaden
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US20080184618A1 (en) * 2005-08-03 2008-08-07 Amcol International Virus-Interacting Layered Phyllosilicates and Methods of Use
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JP5276982B2 (ja) 2005-08-26 2013-08-28 ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ オキシトシンの投与による頭痛の処置のための方法
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EP2429495A4 (de) * 2009-05-15 2014-01-22 Shin Nippon Biomedical Lab Ltd Intranasale pharmazeutische zusammensetzung mit verbesserter pharmakokinetik
US8827946B2 (en) * 2009-07-31 2014-09-09 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator
US10806770B2 (en) 2014-10-31 2020-10-20 Monash University Powder formulation
EP3242676B1 (de) 2015-01-07 2023-10-04 Tonix Pharmaceuticals Holding Corp. Magnesiumhaltige oxytocinformulierungen und verfahren zur verwendung
US20160361253A1 (en) * 2015-06-13 2016-12-15 Noveome Biotherapeutics, Inc. Novel Methods for Delivering Therapeutic Agents to the Eye via Nasal Passages
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
CN110279656B (zh) * 2019-07-11 2021-11-09 温州医科大学 一种用于缓解鼻腔干燥的组合物及其制备方法和使用方法

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Also Published As

Publication number Publication date
DE3886880T2 (de) 1994-07-14
EP0312052A1 (de) 1989-04-19
ES2061591T3 (es) 1994-12-16
JP2851627B2 (ja) 1999-01-27
AU2375188A (en) 1989-06-01
NZ226557A (en) 1990-07-26
US20030181387A1 (en) 2003-09-25
US20050089480A1 (en) 2005-04-28
JPH01132532A (ja) 1989-05-25
AU623609B2 (en) 1992-05-21
US6815424B2 (en) 2004-11-09
US6521597B1 (en) 2003-02-18
ZA887658B (en) 1990-06-27
EP0312052B1 (de) 1994-01-05
CA1336401C (en) 1995-07-25
DE3886880D1 (de) 1994-02-17
KR890006252A (ko) 1989-06-12

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Legal Events

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UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
EEIH Change in the person of patent owner
EELA Cancelled due to lapse of time