ATE548467T1 - Verfahren zur identifizierung von biomarkern mit eignung bei der diagnose biologischer zustände - Google Patents
Verfahren zur identifizierung von biomarkern mit eignung bei der diagnose biologischer zuständeInfo
- Publication number
- ATE548467T1 ATE548467T1 AT06814191T AT06814191T ATE548467T1 AT E548467 T1 ATE548467 T1 AT E548467T1 AT 06814191 T AT06814191 T AT 06814191T AT 06814191 T AT06814191 T AT 06814191T AT E548467 T1 ATE548467 T1 AT E548467T1
- Authority
- AT
- Austria
- Prior art keywords
- biomarkers
- biological conditions
- identifying
- biomarkers useful
- identifying biomarkers
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71413805P | 2005-09-02 | 2005-09-02 | |
| US71362805P | 2005-09-02 | 2005-09-02 | |
| US71362905P | 2005-09-02 | 2005-09-02 | |
| PCT/US2006/034594 WO2007028161A2 (en) | 2005-09-02 | 2006-09-05 | Methods and compositions for identifying biomarkers useful in diagnosis and/or treatment of biological states |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE548467T1 true ATE548467T1 (de) | 2012-03-15 |
Family
ID=37809661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06814191T ATE548467T1 (de) | 2005-09-02 | 2006-09-05 | Verfahren zur identifizierung von biomarkern mit eignung bei der diagnose biologischer zustände |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20070092892A1 (de) |
| EP (2) | EP1934377B1 (de) |
| JP (2) | JP2009506778A (de) |
| AT (1) | ATE548467T1 (de) |
| AU (2) | AU2006287191A1 (de) |
| CA (2) | CA2620521A1 (de) |
| WO (2) | WO2007028161A2 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030186246A1 (en) * | 2002-03-28 | 2003-10-02 | Willey James C. | Multiplex standardized reverse transcriptase-polymerase chain reacton method for assessment of gene expression in small biological samples |
| AU2003223367A1 (en) * | 2002-03-28 | 2003-10-13 | Medical College Of Ohio | Method and compositions for the diagnosis and treatment of non-small cell lung cancer using gene expression profiles |
| CA3084542A1 (en) * | 2003-06-10 | 2005-01-06 | The Trustees Of Boston University | Gene expression analysis of airway epithelial cells for diagnosing lung cancer |
| EP1851334A4 (de) * | 2005-01-21 | 2010-05-26 | Gene Express Inc | Datenbanken zur beurteilung von nukleinsäuren |
| EP2360278A1 (de) * | 2005-04-14 | 2011-08-24 | Trustees Of Boston University | Diagnose für Lungenerkrankungen mittels Klassenvorhersage |
| EP1934377B1 (de) * | 2005-09-02 | 2012-03-07 | The University of Toledo | Verfahren zur identifizierung von biomarkern mit eignung bei der diagnose biologischer zustände |
| WO2009039190A1 (en) * | 2007-09-17 | 2009-03-26 | Gene Express, Inc. | Cancer risk biomarker |
| WO2009039457A1 (en) | 2007-09-19 | 2009-03-26 | The Trustees Of Boston University | Identification of novel pathways for drug development for lung disease |
| WO2009121070A1 (en) * | 2008-03-28 | 2009-10-01 | The Trustees Of Boston University | Multifactorial methods for detecting lung disorders |
| WO2009123990A1 (en) * | 2008-03-31 | 2009-10-08 | The University Of Toledo | Cancer risk biomarker |
| US8348856B1 (en) | 2008-12-16 | 2013-01-08 | Zanetta Malanowska-Stega | Simultaneous multiple method out-patient uterus biopsy device and method |
| US8320655B2 (en) | 2009-10-16 | 2012-11-27 | General Electric Company | Process and system for analyzing the expression of biomarkers in cells |
| US8824769B2 (en) | 2009-10-16 | 2014-09-02 | General Electric Company | Process and system for analyzing the expression of biomarkers in a cell |
| JP2012193121A (ja) * | 2011-03-15 | 2012-10-11 | Kose Corp | マトリックスメタロプロテアーゼ活性阻害剤 |
| CN102435734A (zh) * | 2011-09-08 | 2012-05-02 | 大连医科大学 | 卵巢癌原发化疗敏感性测评试剂盒及其应用 |
| US9944973B2 (en) | 2012-11-26 | 2018-04-17 | The University Of Toledo | Methods for standardized sequencing of nucleic acids and uses thereof |
| EP3626308A1 (de) | 2013-03-14 | 2020-03-25 | Veracyte, Inc. | Verfahren zur bewertung eines copd-status |
| CN103617256B (zh) * | 2013-11-29 | 2018-01-02 | 北京诺禾致源科技股份有限公司 | 待变异检测文件的处理方法及装置 |
| US20170335396A1 (en) | 2014-11-05 | 2017-11-23 | Veracyte, Inc. | Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data |
| WO2017043647A1 (ja) * | 2015-09-11 | 2017-03-16 | 国立研究開発法人理化学研究所 | 転写因子結合部位特異的なｄｎａ脱メチル化方法 |
| US10927417B2 (en) | 2016-07-08 | 2021-02-23 | Trustees Of Boston University | Gene expression-based biomarker for the detection and monitoring of bronchial premalignant lesions |
| KR20190104148A (ko) | 2016-12-09 | 2019-09-06 | 자네타 말라노브스카-스테가 | 브러시 생검 장치, 키트 및 방법 |
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| US5302509A (en) * | 1989-08-14 | 1994-04-12 | Beckman Instruments, Inc. | Method for sequencing polynucleotides |
| AU7547491A (en) * | 1990-03-02 | 1991-09-18 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | An immortalized human bronchial epithelial cell line |
| US5876978A (en) * | 1993-04-06 | 1999-03-02 | Medical College Of Ohio | Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction |
| US5643765A (en) * | 1993-04-06 | 1997-07-01 | University Of Rochester | Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction |
| US5639606A (en) * | 1993-04-06 | 1997-06-17 | The University Of Rochester | Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction |
| WO1995024223A1 (en) * | 1994-03-08 | 1995-09-14 | Thomas Jefferson University | Inhibition of cell proliferation by e2f-1 antisense oligonucleotides |
| US7625697B2 (en) * | 1994-06-17 | 2009-12-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for constructing subarrays and subarrays made thereby |
| US5840506A (en) * | 1996-06-05 | 1998-11-24 | Thomas Jefferson University | Methods for the diagnosis and prognosis of cancer |
| US6303301B1 (en) * | 1997-01-13 | 2001-10-16 | Affymetrix, Inc. | Expression monitoring for gene function identification |
| US7541141B2 (en) * | 1997-02-27 | 2009-06-02 | Wisconsin Alumni Research Foundation | Method of using estrogen-related receptor alpha (ERRα) status to determine prognosis, treatment strategy and predisposition to breast cancer, and method of using ERRα as a therapeutic target for the treatment of breast cancer |
| WO1999032660A1 (en) * | 1997-12-19 | 1999-07-01 | Affymetrix | Exploiting genomics in the search for new drugs |
| US6194038B1 (en) * | 1998-03-20 | 2001-02-27 | Applied Materials, Inc. | Method for deposition of a conformal layer on a substrate |
| US6020135A (en) * | 1998-03-27 | 2000-02-01 | Affymetrix, Inc. | P53-regulated genes |
| US6821724B1 (en) * | 1998-09-17 | 2004-11-23 | Affymetrix, Inc. | Methods of genetic analysis using nucleic acid arrays |
| US6340565B1 (en) * | 1998-11-03 | 2002-01-22 | Affymetrix, Inc. | Determining signal transduction pathways |
| US6177248B1 (en) * | 1999-02-24 | 2001-01-23 | Affymetrix, Inc. | Downstream genes of tumor suppressor WT1 |
| US20030064072A9 (en) * | 1999-03-12 | 2003-04-03 | Rosen Craig A. | Nucleic acids, proteins and antibodies |
| US7056661B2 (en) * | 1999-05-19 | 2006-06-06 | Cornell Research Foundation, Inc. | Method for sequencing nucleic acid molecules |
| US6841348B1 (en) * | 1999-10-21 | 2005-01-11 | Affymetrix, Inc. | Methods for identifying and using maintenance genes |
| AU2001245489A1 (en) * | 2000-03-07 | 2001-09-17 | Whitehead Institute For Biomedical Research | Human single nucleotide polymorphisms |
| DE60136277D1 (de) * | 2000-07-19 | 2008-12-04 | Takara Bio Inc | Verfahren zum nachweis von krebs |
| JP4139085B2 (ja) * | 2001-02-15 | 2008-08-27 | 三星エスディアイ株式会社 | 有機ｅｌデバイスおよびこの製造方法 |
| US20040197785A1 (en) * | 2001-03-14 | 2004-10-07 | Willey James C. | Method for quantitative measurement of gene expression for indentifying individuals at risk for bronchogenic carcinoma |
| WO2003020894A2 (en) * | 2001-08-31 | 2003-03-13 | Joslin Diabetes Center, Inc. | Insulin related transcription factor and uses thereof |
| US7295350B2 (en) * | 2001-09-10 | 2007-11-13 | Transpacific Ip Ltd | Photographic film scanning device |
| US20030144799A1 (en) * | 2001-09-17 | 2003-07-31 | Volker Nowotny | Regulatory single nucleotide polymorphisms and methods therefor |
| WO2003029273A2 (en) * | 2001-09-28 | 2003-04-10 | Whitehead Institute For Biomedical Research | Classification of lung carcinomas using gene expression analysis |
| WO2004001371A2 (en) * | 2001-11-02 | 2003-12-31 | Hybrizyme Corporation | Receptor capture assay |
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| AU2003225573A1 (en) * | 2002-02-13 | 2003-09-04 | The Government Of The United States Of America As Represented By The Secretary, Department Of He | Identification of ovarian cancer tumor markers and therapeutic targets |
| AU2003223367A1 (en) * | 2002-03-28 | 2003-10-13 | Medical College Of Ohio | Method and compositions for the diagnosis and treatment of non-small cell lung cancer using gene expression profiles |
| US20030186246A1 (en) * | 2002-03-28 | 2003-10-02 | Willey James C. | Multiplex standardized reverse transcriptase-polymerase chain reacton method for assessment of gene expression in small biological samples |
| US7222140B2 (en) * | 2002-08-28 | 2007-05-22 | International Business Machines Corporation | Method for improving the recovery time from a lost database in a VTS automation system |
| US7459273B2 (en) * | 2002-10-04 | 2008-12-02 | Affymetrix, Inc. | Methods for genotyping selected polymorphism |
| US20040161779A1 (en) * | 2002-11-12 | 2004-08-19 | Affymetrix, Inc. | Methods, compositions and computer software products for interrogating sequence variations in functional genomic regions |
| US20040146921A1 (en) * | 2003-01-24 | 2004-07-29 | Bayer Pharmaceuticals Corporation | Expression profiles for colon cancer and methods of use |
| US20050042654A1 (en) * | 2003-06-27 | 2005-02-24 | Affymetrix, Inc. | Genotyping methods |
| WO2005003100A2 (en) * | 2003-07-03 | 2005-01-13 | Myriad Genetics, Inc. | 4-arylamino-quinazolines as activators of caspases and inducers of apoptosis |
| WO2005017113A2 (en) * | 2003-08-11 | 2005-02-24 | Lovelace Respiratory Research Institute, Et Al. | Metalloproteinase gene polymorphism in copd |
| AU2005220746A1 (en) * | 2004-03-05 | 2005-09-22 | Medical College Of Ohio | Methods and compositions for assessing nucleic acids and alleles |
| EP1745157A4 (de) * | 2004-04-12 | 2008-06-11 | Ohio Med College | Verfahren und zusammensetzungen zum testen von analyten |
| EP1851334A4 (de) * | 2005-01-21 | 2010-05-26 | Gene Express Inc | Datenbanken zur beurteilung von nukleinsäuren |
| EP1934377B1 (de) * | 2005-09-02 | 2012-03-07 | The University of Toledo | Verfahren zur identifizierung von biomarkern mit eignung bei der diagnose biologischer zustände |
-
2006
- 2006-09-05 EP EP06814191A patent/EP1934377B1/de active Active
- 2006-09-05 US US11/470,185 patent/US20070092892A1/en not_active Abandoned
- 2006-09-05 US US11/470,192 patent/US20070092893A1/en not_active Abandoned
- 2006-09-05 CA CA002620521A patent/CA2620521A1/en not_active Abandoned
- 2006-09-05 US US11/470,159 patent/US20070092891A1/en not_active Abandoned
- 2006-09-05 WO PCT/US2006/034594 patent/WO2007028161A2/en active Application Filing
- 2006-09-05 AT AT06814191T patent/ATE548467T1/de active
- 2006-09-05 EP EP06814192A patent/EP1940860B1/de active Active
- 2006-09-05 AU AU2006287191A patent/AU2006287191A1/en not_active Abandoned
- 2006-09-05 WO PCT/US2006/034595 patent/WO2007028162A2/en active Application Filing
- 2006-09-05 JP JP2008529374A patent/JP2009506778A/ja active Pending
- 2006-09-05 AU AU2006287190A patent/AU2006287190A1/en not_active Abandoned
- 2006-09-05 JP JP2008529373A patent/JP2009507229A/ja active Pending
- 2006-09-05 CA CA002620528A patent/CA2620528A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1940860B1 (de) | 2012-08-08 |
| CA2620528A1 (en) | 2007-03-08 |
| EP1934377B1 (de) | 2012-03-07 |
| AU2006287191A1 (en) | 2007-03-08 |
| JP2009506778A (ja) | 2009-02-19 |
| JP2009507229A (ja) | 2009-02-19 |
| WO2007028161A3 (en) | 2008-10-16 |
| EP1940860A2 (de) | 2008-07-09 |
| US20070092892A1 (en) | 2007-04-26 |
| EP1934377A2 (de) | 2008-06-25 |
| US20070092891A1 (en) | 2007-04-26 |
| WO2007028162A3 (en) | 2007-07-05 |
| EP1940860A4 (de) | 2009-04-22 |
| EP1934377A4 (de) | 2009-04-22 |
| CA2620521A1 (en) | 2007-03-08 |
| WO2007028161A2 (en) | 2007-03-08 |
| US20070092893A1 (en) | 2007-04-26 |
| WO2007028162A2 (en) | 2007-03-08 |
| AU2006287190A1 (en) | 2007-03-08 |
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