ATE532507T1 - Neramexane zur behandlung von subakuten tinnitus - Google Patents
Neramexane zur behandlung von subakuten tinnitusInfo
- Publication number
- ATE532507T1 ATE532507T1 AT08801987T AT08801987T ATE532507T1 AT E532507 T1 ATE532507 T1 AT E532507T1 AT 08801987 T AT08801987 T AT 08801987T AT 08801987 T AT08801987 T AT 08801987T AT E532507 T1 ATE532507 T1 AT E532507T1
- Authority
- AT
- Austria
- Prior art keywords
- neramexane
- treatment
- subacute
- tinnitus
- subacute tinnitus
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99339607P | 2007-09-12 | 2007-09-12 | |
EP07253630 | 2007-09-12 | ||
US6702608P | 2008-02-25 | 2008-02-25 | |
US6708308P | 2008-02-25 | 2008-02-25 | |
US6693108P | 2008-02-25 | 2008-02-25 | |
EP08004776 | 2008-03-14 | ||
EP08004777 | 2008-03-14 | ||
EP08004778 | 2008-03-14 | ||
PCT/EP2008/007421 WO2009033652A1 (en) | 2007-09-12 | 2008-09-10 | 1-amino-alkylcyclohexane derivatives for the treatment of cochlear tinnitus |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE532507T1 true ATE532507T1 (de) | 2011-11-15 |
Family
ID=40451596
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT08801987T ATE532507T1 (de) | 2007-09-12 | 2008-09-10 | Neramexane zur behandlung von subakuten tinnitus |
Country Status (21)
Country | Link |
---|---|
US (6) | US9468610B2 (de) |
EP (6) | EP2200600B1 (de) |
JP (6) | JP5613053B2 (de) |
KR (4) | KR20100052556A (de) |
CN (4) | CN101795679A (de) |
AR (3) | AR070026A1 (de) |
AT (1) | ATE532507T1 (de) |
AU (4) | AU2008298016B2 (de) |
BR (2) | BRPI0816690A2 (de) |
CA (4) | CA2699209A1 (de) |
DK (1) | DK2200600T3 (de) |
ES (5) | ES2562709T3 (de) |
HR (1) | HRP20120046T1 (de) |
MX (4) | MX2010002736A (de) |
PL (1) | PL2200600T3 (de) |
PT (1) | PT2200600E (de) |
RU (1) | RU2011137131A (de) |
SI (1) | SI2200600T1 (de) |
TW (3) | TW200918042A (de) |
WO (4) | WO2009033650A1 (de) |
ZA (4) | ZA201001262B (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101795679A (zh) * | 2007-09-12 | 2010-08-04 | 莫茨药物股份两合公司 | 用于治疗耳蜗性耳鸣的1-氨基-烷基环己烷衍生物 |
US20110294890A1 (en) | 2010-05-28 | 2011-12-01 | Merz Pharma Gmbh & Co. Kgaa | Neramexane for the treatment or prevention of inner ear disorders |
JP2013529604A (ja) * | 2010-06-24 | 2013-07-22 | メルツ ファーマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディト ゲゼルシャフト アウフ アクティーン | ネラメキサン複数単位剤形 |
WO2012098000A1 (en) | 2011-01-20 | 2012-07-26 | Merz Pharma Gmbh & Co. Kgaa | Neramexane for the treatment or prevention of tinnitus related with stress or acute hearing loss |
WO2014138502A1 (en) * | 2013-03-06 | 2014-09-12 | Acorda Therapeutics, Inc. | Therapeutic dosing of a neuregulin or a fragment thereof for treatment or prophylaxis of heart failure |
JP5978472B2 (ja) * | 2014-04-28 | 2016-08-24 | 杏林製薬株式会社 | 耳鳴患者の治療用の薬剤 |
BR112016024918A2 (pt) * | 2014-04-28 | 2017-08-15 | Kyorin Seiyaku Kk | ?uso de uma droga? |
CA2999467C (en) * | 2014-10-23 | 2023-10-10 | Arena Pharmaceuticals, Inc. | Method of treating conditions related to the pgi2 receptor |
ES2882602T3 (es) * | 2015-05-18 | 2021-12-02 | Sensorion | Azasetrón para usar en el tratamiento de la pérdida auditiva |
KR101893604B1 (ko) | 2015-08-27 | 2018-08-30 | 경희대학교 산학협력단 | 칸디다 유틸리스 추출물을 포함하는 난청의 예방 또는 치료용 조성물 |
CN105924362B (zh) * | 2016-02-05 | 2018-08-17 | 上海龙翔生物医药开发有限公司 | 芳香环丙基胺类化合物、其药学上可接受的盐、其制备方法及其用途 |
CN110582271B (zh) | 2017-03-01 | 2022-06-14 | 阿瑞那制药公司 | 包含pgi2受体激动剂的组合物及其制备方法 |
KR102268893B1 (ko) | 2020-01-16 | 2021-06-24 | 경북대학교 산학협력단 | 림노트릭스 속 knua002 균주를 포함하는 난청의 예방 또는 치료용 조성물 |
CN111477199B (zh) * | 2020-04-02 | 2021-11-30 | 北京瑞迪欧文化传播有限责任公司 | 一种嵌入式音乐控制*** |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5811128A (en) | 1986-10-24 | 1998-09-22 | Southern Research Institute | Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor |
US4849222A (en) | 1987-03-24 | 1989-07-18 | The Procter & Gamble Company | Mixtures for treating hypercholesterolemia |
JP2670680B2 (ja) | 1988-02-24 | 1997-10-29 | 株式会社ビーエムジー | 生理活性物質含有ポリ乳酸系微小球およびその製造法 |
US5288502A (en) | 1991-10-16 | 1994-02-22 | The University Of Texas System | Preparation and uses of multi-phase microspheres |
JPH09504027A (ja) | 1993-10-22 | 1997-04-22 | ジェネンテク,インコーポレイテッド | ワクチンとしての使用のための抗原のマイクロカプセル化のための方法および組成物 |
DE19528388A1 (de) * | 1995-08-02 | 1997-02-06 | Hans Peter Prof Dr Med Zenner | Verwendung von Adamantan-Derivaten zur Behandlung von Erkrankungen des Innenohrs |
AU4424697A (en) | 1996-09-11 | 1998-04-02 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | The use of functional n-methyl-d-aspartate antagonists to ameliorate or prevent aminoglycoside-induced ototoxicity |
US6071966A (en) | 1997-06-30 | 2000-06-06 | Merz + Co. Gmbh & Co. | 1-amino-alkylcyclohexane NMDA receptor antagonists |
PL193237B1 (pl) * | 1997-06-30 | 2007-01-31 | Merz Pharma Gmbh & Co Kgaa | Pochodne 1-aminoalkilocykloheksanu, kompozycja farmaceutyczna je zawierająca oraz ich zastosowanie |
CA2406272A1 (en) | 2000-04-26 | 2001-11-01 | Warner Lambert Company | Cyclohexylamine derivative as subtype selective nmda receptor antagonists |
DE10048969A1 (de) * | 2000-08-23 | 2002-03-14 | Mueller Schwefe Gerhard | Verwendung von Flupirtin zur Tinnitusbehandlung |
US20030236288A1 (en) * | 2002-02-28 | 2003-12-25 | Karl Schoenafinger | Use of substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadizol-2-ones for inhibiting pancreatic lipase |
JP2004021734A (ja) | 2002-06-18 | 2004-01-22 | Nokia Corp | キーパッドおよびキーパッドシステム |
US7086532B2 (en) * | 2003-07-16 | 2006-08-08 | Allergan, Inc. | Titration/compliance pack with increasing doses |
JP2006502158A (ja) * | 2002-09-06 | 2006-01-19 | デュレクト コーポレーション | グルタメート媒介神経伝達のモジュレーターの内耳への送達 |
DE10252665A1 (de) * | 2002-11-11 | 2004-06-03 | Grünenthal GmbH | 4-Aminomethyl-1-aryl-cyclohexylamin-Derivate |
JP2007500238A (ja) | 2003-05-27 | 2007-01-11 | フォーレスト ラボラトリーズ, インコーポレイテッド | うつ病及びその他の気分障害のために、nmda受容体アンタゴニストと選択的セロトニン再取り込み阻害薬の併用 |
AR046314A1 (es) | 2003-11-05 | 2005-11-30 | Merz Pharma Gmbh & Co Kgaa | Composiciones que comprenden ciclohexilaminas y aminoadamantanos |
EP2397122B1 (de) * | 2004-06-17 | 2014-05-14 | Merz Pharma GmbH & Co. KGaA | Formulierungen aus Neramexan-Dosierformen |
US20060002999A1 (en) * | 2004-06-17 | 2006-01-05 | Forest Laboratories, Inc. | Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane |
US20060205822A1 (en) * | 2004-12-22 | 2006-09-14 | Forest Laboratories, Inc. | 1-Aminocyclohexane derivatives for the treatment of multiple sclerosis, emotional lability and pseudobulbar affect |
WO2006079055A2 (en) * | 2005-01-24 | 2006-07-27 | Neurosystec Corporation | Apparatus and method for delivering therapeutic and/or other agents to the inner ear and to other tissues |
CN101163481A (zh) * | 2005-03-04 | 2008-04-16 | 纽罗赛斯特克公司 | 改进的加环利定制剂 |
TWI265036B (en) * | 2005-04-29 | 2006-11-01 | Guo-Ming Huang | Safety injector and method of operating the same |
CN101175458B (zh) * | 2005-05-18 | 2010-08-18 | Gt泌尿学公司 | 可植入失禁用设备的药物洗脱 |
CN1896729A (zh) | 2005-07-15 | 2007-01-17 | 复旦大学附属中山医院 | 纳米药物自组装双稳态量子线阵列及其制备方法 |
US20070141148A1 (en) | 2005-11-30 | 2007-06-21 | Merz Pharma Gmbh & Co. Kgaa | Neramexane MR matrix tablet |
TW200819458A (en) * | 2006-06-23 | 2008-05-01 | Merz Pharma Gmbh & Co Kgaa | Metabotropic glutamate receptor modulators |
CN101795679A (zh) * | 2007-09-12 | 2010-08-04 | 莫茨药物股份两合公司 | 用于治疗耳蜗性耳鸣的1-氨基-烷基环己烷衍生物 |
TW201010691A (en) * | 2008-06-12 | 2010-03-16 | Merz Pharma Gmbh & Co Kgaa | 1-amino-alkylcyclohexane derivatives for the treatment of sleep disorders |
TW201006463A (en) * | 2008-06-26 | 2010-02-16 | Merz Pharma Gmbh & Co Kgaa | Pharmaceutical compositions comprising aminocyclohexane derivatives |
RU2011113733A (ru) * | 2008-09-10 | 2012-10-20 | Мерц Фарма Гмбх Унд Ко. Кгаа (De) | Производные 1-амино-алкилциклогексана для лечения когнитивного нарушения при шуме в ушах |
US20110294890A1 (en) * | 2010-05-28 | 2011-12-01 | Merz Pharma Gmbh & Co. Kgaa | Neramexane for the treatment or prevention of inner ear disorders |
WO2012098000A1 (en) * | 2011-01-20 | 2012-07-26 | Merz Pharma Gmbh & Co. Kgaa | Neramexane for the treatment or prevention of tinnitus related with stress or acute hearing loss |
-
2008
- 2008-09-10 CN CN200880106975A patent/CN101795679A/zh active Pending
- 2008-09-10 CA CA2699209A patent/CA2699209A1/en not_active Abandoned
- 2008-09-10 AR ARP080103937A patent/AR070026A1/es not_active Application Discontinuation
- 2008-09-10 TW TW097134699A patent/TW200918042A/zh unknown
- 2008-09-10 DK DK08801987.2T patent/DK2200600T3/da active
- 2008-09-10 CA CA2699207A patent/CA2699207A1/en not_active Abandoned
- 2008-09-10 AR ARP080103938A patent/AR071728A1/es not_active Application Discontinuation
- 2008-09-10 CA CA2699210A patent/CA2699210A1/en not_active Abandoned
- 2008-09-10 EP EP08801987A patent/EP2200600B1/de active Active
- 2008-09-10 WO PCT/EP2008/007419 patent/WO2009033650A1/en active Application Filing
- 2008-09-10 KR KR1020107007786A patent/KR20100052556A/ko not_active Application Discontinuation
- 2008-09-10 ES ES12006826.7T patent/ES2562709T3/es active Active
- 2008-09-10 EP EP08801985.6A patent/EP2200599B1/de active Active
- 2008-09-10 AR ARP080103936A patent/AR070025A1/es not_active Application Discontinuation
- 2008-09-10 AU AU2008298016A patent/AU2008298016B2/en not_active Ceased
- 2008-09-10 ES ES08801986.4T patent/ES2510565T3/es active Active
- 2008-09-10 JP JP2010524392A patent/JP5613053B2/ja not_active Expired - Fee Related
- 2008-09-10 US US12/733,582 patent/US9468610B2/en not_active Expired - Fee Related
- 2008-09-10 EP EP12006826.7A patent/EP2548552B1/de active Active
- 2008-09-10 AU AU2008298015A patent/AU2008298015B2/en not_active Ceased
- 2008-09-10 ES ES08801985.6T patent/ES2604945T3/es active Active
- 2008-09-10 US US12/733,577 patent/US20110086916A1/en not_active Abandoned
- 2008-09-10 CN CN200880106973A patent/CN101801366A/zh active Pending
- 2008-09-10 MX MX2010002736A patent/MX2010002736A/es not_active Application Discontinuation
- 2008-09-10 AU AU2008298017A patent/AU2008298017B2/en not_active Ceased
- 2008-09-10 US US12/733,646 patent/US9498450B2/en not_active Expired - Fee Related
- 2008-09-10 EP EP08801984A patent/EP2200598A1/de not_active Withdrawn
- 2008-09-10 BR BRPI0816690A patent/BRPI0816690A2/pt not_active IP Right Cessation
- 2008-09-10 WO PCT/EP2008/007420 patent/WO2009033651A1/en active Application Filing
- 2008-09-10 MX MX2010002734A patent/MX2010002734A/es not_active Application Discontinuation
- 2008-09-10 EP EP08801986.4A patent/EP2203163B1/de active Active
- 2008-09-10 CA CA2699213A patent/CA2699213A1/en not_active Abandoned
- 2008-09-10 JP JP2010524395A patent/JP5563461B2/ja not_active Expired - Fee Related
- 2008-09-10 ES ES11005567.0T patent/ES2596262T3/es active Active
- 2008-09-10 WO PCT/EP2008/007421 patent/WO2009033652A1/en active Application Filing
- 2008-09-10 JP JP2010524394A patent/JP5563460B2/ja not_active Expired - Fee Related
- 2008-09-10 PL PL08801987T patent/PL2200600T3/pl unknown
- 2008-09-10 MX MX2010002733A patent/MX2010002733A/es not_active Application Discontinuation
- 2008-09-10 SI SI200830530T patent/SI2200600T1/sl unknown
- 2008-09-10 US US12/733,645 patent/US8877814B2/en not_active Expired - Fee Related
- 2008-09-10 EP EP11005567.0A patent/EP2386299B1/de active Active
- 2008-09-10 TW TW097134705A patent/TW200922544A/zh unknown
- 2008-09-10 AU AU2008298018A patent/AU2008298018C1/en not_active Ceased
- 2008-09-10 AT AT08801987T patent/ATE532507T1/de active
- 2008-09-10 ES ES08801987T patent/ES2377253T3/es active Active
- 2008-09-10 CN CN200880106925A patent/CN101801365A/zh active Pending
- 2008-09-10 JP JP2010524393A patent/JP5612473B2/ja not_active Expired - Fee Related
- 2008-09-10 CN CN200880106404A patent/CN101835469A/zh active Pending
- 2008-09-10 BR BRPI0816712A patent/BRPI0816712A2/pt not_active IP Right Cessation
- 2008-09-10 KR KR1020107007787A patent/KR20100052557A/ko not_active Application Discontinuation
- 2008-09-10 TW TW097134701A patent/TW200927087A/zh unknown
- 2008-09-10 WO PCT/EP2008/007418 patent/WO2009033649A1/en active Application Filing
- 2008-09-10 KR KR1020107007793A patent/KR20100052558A/ko not_active Application Discontinuation
- 2008-09-10 PT PT08801987T patent/PT2200600E/pt unknown
- 2008-09-10 KR KR1020107007795A patent/KR20100052559A/ko not_active Application Discontinuation
- 2008-09-10 MX MX2010002735A patent/MX2010002735A/es unknown
-
2010
- 2010-02-22 ZA ZA2010/01262A patent/ZA201001262B/en unknown
- 2010-02-22 ZA ZA2010/01261A patent/ZA201001261B/en unknown
- 2010-02-22 ZA ZA2010/01264A patent/ZA201001264B/en unknown
- 2010-02-22 ZA ZA2010/01263A patent/ZA201001263B/en unknown
-
2011
- 2011-09-08 RU RU2011137131/15A patent/RU2011137131A/ru not_active Application Discontinuation
-
2012
- 2012-01-16 HR HR20120046T patent/HRP20120046T1/hr unknown
-
2014
- 2014-06-12 JP JP2014121269A patent/JP5784189B2/ja not_active Expired - Fee Related
- 2014-06-12 JP JP2014121268A patent/JP5784188B2/ja not_active Expired - Fee Related
- 2014-09-30 US US14/501,438 patent/US20150018425A1/en not_active Abandoned
-
2016
- 2016-10-12 US US15/291,527 patent/US20170027885A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE532507T1 (de) | Neramexane zur behandlung von subakuten tinnitus | |
ATE434620T1 (de) | Dihydrothienopyrimidine zur behandlung von entzündlichen erkrankungen | |
BRPI0920104A2 (pt) | tratamento de soluções ou de águas residuais | |
ATE545418T1 (de) | Zusammensetzungen und kits zur behandlung von influenza | |
ATE429218T1 (de) | Pinolensäure zur behandlung von übergewicht | |
ATE550329T1 (de) | Heterobicyclische sulfonamidderivate zur behandlung von diabetes | |
LTC2330892I2 (lt) | Gydymo būdai panaudojant vaistus - amoniako gaudykles | |
ATE527241T1 (de) | Pyridiazinonderivate zur behandlung von tumoren | |
DK2504005T3 (da) | Anvendelse af 1,3-diphenylprop-2-en-1-on-derivater til behandling af lever-sygdomme | |
SE0702104L (sv) | Förfarande för behandling av avfall | |
ATE521365T1 (de) | Kinin-antagonisten zur behandlung von blasenfunktionsstörung | |
FI20085275A0 (fi) | Menetelmä biomassan käsittelemiseksi | |
ATE534633T1 (de) | Indazolderivate zur behandlung von hsp90- induzierten krankheiten | |
DK2330887T3 (da) | Behandlingsindretning | |
ATE502944T1 (de) | 2-amino-5,7-dihydro-6h-pyrroloä3,4- düpyrimidinderivate als hsp-90-inhibitoren zur behandlung von krebs | |
DE112010005017A5 (de) | Beta-carboline zur behandlung von hörschäden und schwindel | |
ATE525904T1 (de) | Behandlung von bananen | |
BRPI0912687A2 (pt) | uso de bactéria probiótica para o tratamento de hiperhomocisteinaemia | |
BRPI0916079A2 (pt) | tratamento de água marinha residual | |
DK2117565T3 (da) | Anvendelse af chitosaner til behandlingen af negleinflammatoriske sygdomme | |
ATE504297T1 (de) | Visnadin zur behandlung von kopfhautjucken | |
DE602005016141D1 (de) | S-mirtazapin zur behandlung von hitzewallungen | |
ATE516805T1 (de) | Medikament zur behandlung von endometriose | |
DK2297047T3 (da) | Indretning til rensning af spildevand | |
DK2293810T3 (da) | Muteret tat-oyi-protein til forebyggelse eller behandling af aids |