ATE528310T1 - Verfahren zur synthese von alkylphosphinsäuren durch initiierung eines amins und eines aminoxids - Google Patents

Verfahren zur synthese von alkylphosphinsäuren durch initiierung eines amins und eines aminoxids

Info

Publication number: ATE528310T1
Authority: AT; Austria
Prior art keywords: amine; synthesis; acids; alkylphosphic; initiating
Prior art date: 2007-05-04

Application number

AT08779297T

Other languages

English (en)

Inventor

Daniel Finnhult

Roger Sohlberg

Fredrik Stalfors

Carina Svensson

Johanna Wachtmeister

Thomas Waennman

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-05-04

Filing date

2008-04-30

Publication date

2011-10-15

2008-04-30 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2011-10-15 Application granted granted Critical

2011-10-15 Publication of ATE528310T1 publication Critical patent/ATE528310T1/de

Links

239000002253 acid Substances 0.000 title abstract 2
150000007513 acids Chemical class 0.000 title abstract 2
230000015572 biosynthetic process Effects 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
238000003786 synthesis reaction Methods 0.000 title abstract 2
230000000977 initiatory effect Effects 0.000 title 1
SBOJXQVPLKSXOG-UHFFFAOYSA-N o-amino-hydroxylamine Chemical compound NON SBOJXQVPLKSXOG-UHFFFAOYSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 1
150000001350 alkyl halides Chemical class 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
238000005859 coupling reaction Methods 0.000 abstract 1
ACVYVLVWPXVTIT-UHFFFAOYSA-N phosphinic acid Chemical class O[PH2]=O ACVYVLVWPXVTIT-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/48—Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof
- C07F9/4808—Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof the acid moiety containing a substituent or structure which is considered as characteristic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/48—Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof
- C07F9/4808—Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof the acid moiety containing a substituent or structure which is considered as characteristic
- C07F9/4816—Acyclic saturated acids or derivatices which can have further substituents on alkyl

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

AT08779297T 2007-05-04 2008-04-30 Verfahren zur synthese von alkylphosphinsäuren durch initiierung eines amins und eines aminoxids ATE528310T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US91597907P	2007-05-04	2007-05-04
PCT/SE2008/050496 WO2008136746A1 (en)	2007-05-04	2008-04-30	Process for the synthesis of alkyl phosphinic acids by initiation of an amine and an amineoxide

Publications (1)

Publication Number	Publication Date
ATE528310T1 true ATE528310T1 (de)	2011-10-15

Family

ID=39943754

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT08779297T ATE528310T1 (de)	2007-05-04	2008-04-30	Verfahren zur synthese von alkylphosphinsäuren durch initiierung eines amins und eines aminoxids

Country Status (8)

Country	Link
US (1)	US8026384B2 (de)
EP (1)	EP2155762B1 (de)
JP (1)	JP5520816B2 (de)
CN (1)	CN101675064B (de)
AT (1)	ATE528310T1 (de)
ES (1)	ES2373255T3 (de)
HK (1)	HK1141030A1 (de)
WO (1)	WO2008136746A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5500343B2 (ja) *	2009-11-18	2014-05-21	セントラル硝子株式会社	光学活性３−ｔｅｒｔ−ブトキシカルボニルアミノ−２−フルオロ−１−プロパノールの製造方法
CN110726801A (zh) *	2019-10-31	2020-01-24	山东泰星新材料股份有限公司	一种监测烷基次膦酸反应状态的方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL145897B (nl) *	1948-04-12		Union Carbide Corp	Werkwijze voor het bereiden van korrelvormige wasmiddelen.
US4632741A (en) *	1984-09-06	1986-12-30	Economics Laboratory, Inc.	Synthesis of alkyl phosphinate salts and bis(alkyl) phosphinate salts
EP0343307A1 (de)	1988-05-26	1989-11-29	Fabrica Espanola De Productos Quimicos Y Farmaceuticos, S.A.	4-Piperidinalkanamin-Derivate
DE4234295A1 (de) *	1992-10-12	1994-04-14	Thomae Gmbh Dr K	Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
CA2243445A1 (en) *	1996-11-19	1998-05-28	Nisshin Flour Milling Co. Ltd.	Pyridinecarboxamide derivatives
FR2788272B1 (fr) *	1999-01-08	2001-03-16	Atochem Elf Sa	Procede de preparation de nitroxydes
DE19923619C2 (de)	1999-05-25	2001-08-23	Clariant Gmbh	Verfahren zur Herstellung von Dialkylphosphinsäuren und deren Salzen
SE9904508D0 (sv) *	1999-12-09	1999-12-09	Astra Ab	New compounds
SE9904507D0 (sv)	1999-12-09	1999-12-09	Astra Ab	New compounds
JP2005508907A (ja)	2001-09-14	2005-04-07	ノボ　ノルディスク　アクティーゼルスカブ	ヒスタミンｈ３受容体に選択的に結合する置換されたピペリジン
US6673829B2 (en) *	2001-09-14	2004-01-06	Novo Nordisk A/S	Aminoazetidine,-pyrrolidine and -piperidine derivatives
US7064135B2 (en) *	2001-10-12	2006-06-20	Novo Nordisk Inc.	Substituted piperidines
AU2003274053A1 (en)	2002-10-22	2004-05-13	Glaxo Group Limited	Aryloxyalkylamine derivates as h3 receptor ligands
US7332508B2 (en)	2002-12-18	2008-02-19	Novo Nordisk A/S	Substituted homopiperidine, piperidine or pyrrolidine derivatives
US7547693B2 (en)	2003-09-22	2009-06-16	Banyu Pharmaceutical Co. Ltd.	Piperidine derivative
US8097747B2 (en) *	2004-04-23	2012-01-17	ICL-IP America Inc	Process for the alkylation of phosphorus-containing compounds
SE0402462D0 (sv)	2004-10-08	2004-10-08	Astrazeneca Ab	New process

2008
- 2008-04-30 US US12/598,782 patent/US8026384B2/en not_active Expired - Fee Related
- 2008-04-30 WO PCT/SE2008/050496 patent/WO2008136746A1/en active Application Filing
- 2008-04-30 JP JP2010506139A patent/JP5520816B2/ja not_active Expired - Fee Related
- 2008-04-30 CN CN2008800147954A patent/CN101675064B/zh not_active Expired - Fee Related
- 2008-04-30 ES ES08779297T patent/ES2373255T3/es active Active
- 2008-04-30 EP EP08779297A patent/EP2155762B1/de not_active Not-in-force
- 2008-04-30 AT AT08779297T patent/ATE528310T1/de not_active IP Right Cessation
2010
- 2010-08-04 HK HK10107443.6A patent/HK1141030A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
US8026384B2 (en)	2011-09-27
CN101675064B (zh)	2012-11-14
EP2155762A4 (de)	2011-02-09
JP2010526061A (ja)	2010-07-29
WO2008136746A1 (en)	2008-11-13
HK1141030A1 (en)	2010-10-29
EP2155762B1 (de)	2011-10-12
US20100130773A1 (en)	2010-05-27
CN101675064A (zh)	2010-03-17
EP2155762A1 (de)	2010-02-24
JP5520816B2 (ja)	2014-06-11
ES2373255T3 (es)	2012-02-01

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Legal Events

Date	Code	Title	Description
2012-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties