ATE478559T1 - Nachweis von protease und protease-aktivität mithilfe einer einzel-nanosteigerungs-sers-sonde - Google Patents
Nachweis von protease und protease-aktivität mithilfe einer einzel-nanosteigerungs-sers-sondeInfo
- Publication number
- ATE478559T1 ATE478559T1 AT07835744T AT07835744T ATE478559T1 AT E478559 T1 ATE478559 T1 AT E478559T1 AT 07835744 T AT07835744 T AT 07835744T AT 07835744 T AT07835744 T AT 07835744T AT E478559 T1 ATE478559 T1 AT E478559T1
- Authority
- AT
- Austria
- Prior art keywords
- protease
- detection
- peptide
- single nano
- sers probe
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- G01N33/587—Nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96466—Cysteine endopeptidases (3.4.22)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/974—Thrombin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Nanotechnology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Detergent Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79752506P | 2006-05-03 | 2006-05-03 | |
PCT/US2007/010722 WO2008018933A2 (en) | 2006-05-03 | 2007-05-02 | Detection of protease and protease activity using a single nanocrescent sers probe |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE478559T1 true ATE478559T1 (de) | 2010-09-15 |
Family
ID=39033446
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07835744T ATE478559T1 (de) | 2006-05-03 | 2007-05-02 | Nachweis von protease und protease-aktivität mithilfe einer einzel-nanosteigerungs-sers-sonde |
Country Status (10)
Country | Link |
---|---|
US (2) | US8361932B2 (de) |
EP (1) | EP2019587B1 (de) |
JP (1) | JP2009535060A (de) |
KR (1) | KR20090009302A (de) |
CN (1) | CN101484002B (de) |
AT (1) | ATE478559T1 (de) |
AU (1) | AU2007282164A1 (de) |
CA (1) | CA2679707A1 (de) |
DE (1) | DE602007008716D1 (de) |
WO (1) | WO2008018933A2 (de) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100041016A1 (en) | 2005-10-17 | 2010-02-18 | Sword Diagnostics, Inc. | Methods for detecting organisms and enzymatic reactions using raman spectroscopy and aromatic compounds comprising phosphate |
PL1946083T3 (pl) | 2005-10-17 | 2012-04-30 | Sword Diagnostics Inc | Sposób wykrywania organizmów biologicznych wykorzystujący rozpraszanie ramanowskie |
US7947437B2 (en) * | 2005-10-17 | 2011-05-24 | Sword Diagnostics, Inc. | Methods for detecting organisms and enzymatic reactions using raman spectroscopy |
ATE478559T1 (de) | 2006-05-03 | 2010-09-15 | Univ California | Nachweis von protease und protease-aktivität mithilfe einer einzel-nanosteigerungs-sers-sonde |
KR100857770B1 (ko) * | 2007-04-11 | 2008-09-09 | 한국과학기술연구원 | 단백질 분해효소 검출 및 생체 내 영상화를 위한 금속 나노입자 및 그것의 용도 |
CN104155282A (zh) | 2007-11-02 | 2014-11-19 | 加利福尼亚大学董事会 | 纳米等离子体激元共振器 |
JP5620154B2 (ja) * | 2009-10-15 | 2014-11-05 | 公益財団法人神奈川科学技術アカデミー | 中空微小体およびその作製方法 |
US20130029360A1 (en) * | 2009-12-11 | 2013-01-31 | Snu R&Db Foundation | Dimeric core-shell nanostructure labeled with raman active molecule localized at interparticle junction, use thereof, and method for preparing the same |
EP2547732B1 (de) * | 2010-03-15 | 2018-02-28 | Purdue Research Foundation | Farbstoffe mit strukturen höherer ordnung und verbesserten optischen merkmalen |
CN102175705B (zh) * | 2011-03-11 | 2012-08-22 | 中国科学院半导体研究所 | 双新月对结构的化学传感*** |
KR101361652B1 (ko) * | 2011-05-29 | 2014-02-14 | 한국화학연구원 | 라만 분석 기반 고속 다중 약물 고속 스크리닝 장치 |
CN102590509A (zh) * | 2012-03-20 | 2012-07-18 | 湖南大学 | 基于无修饰抗体介导纳米金组装检测组蛋白修饰酶活性及筛选其抑制剂的生物传感方法 |
AU2013329110B2 (en) | 2012-10-12 | 2017-05-04 | Sage Science, Inc. | Side-eluting molecular fractionator |
WO2014080519A1 (ja) * | 2012-11-26 | 2014-05-30 | 独立行政法人産業技術総合研究所 | ナノカーボンを用いた臨床検査 |
CN107076724B (zh) * | 2013-03-29 | 2020-03-03 | 国立大学法人三重大学 | 生物体染色剂 |
CN105021819B (zh) * | 2014-04-28 | 2017-05-03 | 中国科学院苏州纳米技术与纳米仿生研究所 | 荧光纳米磁性粒子‑多肽底物复合体及其制备方法 |
CN104122248A (zh) * | 2014-07-03 | 2014-10-29 | 上海师范大学 | 一种具有表面增强拉曼效应的Fe3+的拉曼探针及其制备方法和应用 |
EP3207163B1 (de) | 2014-10-15 | 2020-05-27 | Sage Science, Inc. | Vorrichtungen, verfahren und systeme zur automatisierten verarbeitung von nukleinsäuren und elektrophoretischen probenvorbereitung |
CN104892541A (zh) * | 2015-05-28 | 2015-09-09 | 中国科学院化学研究所 | 一种用于γ-谷氨酰转肽酶检测的荧光探针及其制备方法与应用 |
CN105199422B (zh) * | 2015-10-20 | 2017-05-10 | 北京科技大学 | 含巯基基团的联噻吩苯并吲哚盐染料及其制备方法和应用 |
WO2017087835A1 (en) * | 2015-11-19 | 2017-05-26 | Howard University | Composition, method of manufacture, and use of site-specific delivery of bruceolides for treatment of cancer and other diseases |
JP7054678B2 (ja) | 2015-11-20 | 2022-04-14 | ワシントン・ユニバーシティ | ゲノムdna断片の標的化された精製のための調製用電気泳動方法 |
FR3044415B1 (fr) * | 2015-11-27 | 2017-12-01 | Biomerieux Sa | Procede de determination de la reaction d'un microorganisme a son exposition a un antibiotique |
WO2017139669A1 (en) * | 2016-02-11 | 2017-08-17 | Sage Science, Inc. | Workflows for enzymatic nucleic acid modification |
CN106290873B (zh) * | 2016-07-28 | 2018-03-30 | 江南大学 | 一种基于具有拉曼和荧光双重信号的金‑上转换空间四面体结构的制备及应用 |
CN106290898B (zh) * | 2016-07-29 | 2017-11-28 | 江南大学 | 一种金‑上转换纳米粒子三聚体的制备方法及其应用 |
CA3037767A1 (en) * | 2016-09-28 | 2018-04-05 | Georgia Tech Research Corporation | Methods and compositions for noninvasive detection of organ transplant rejection |
JP2017032580A (ja) * | 2016-10-05 | 2017-02-09 | ヒューレット−パッカード デベロップメント カンパニー エル.ピー.Hewlett‐Packard Development Company, L.P. | 化学的な検知器 |
CA3055306A1 (en) | 2017-04-07 | 2018-10-11 | Sage Science, Inc. | Systems and methods for detection of genetic structural variation using integrated electrophoretic dna purification |
US10156658B1 (en) * | 2017-06-06 | 2018-12-18 | Saudi Arabian Oil Company | Detecting a tracer in a hydrocarbon reservoir |
GB201710401D0 (en) * | 2017-06-29 | 2017-08-16 | Vib Vzw | Label free detection of protease activity |
CN107727632B (zh) * | 2017-08-22 | 2020-08-04 | 陕西专壹知识产权运营有限公司 | 一种sers增强的可控链状组装体检测凝血酶的方法 |
EP3460472A1 (de) * | 2017-09-22 | 2019-03-27 | Nokia Technologies Oy | Funktionalisierte partikel |
EP3593708A1 (de) * | 2018-07-13 | 2020-01-15 | Nokia Technologies Oy | Künstliche haut |
KR102230533B1 (ko) * | 2019-03-05 | 2021-03-19 | 서강대학교산학협력단 | 전도성 고분자 나노 구조체 및 금속 나노입자 복합체를 이용한 표면증강 라만분광 기반 단백질 분해 효소 검출용 센서 |
JP7479051B2 (ja) | 2019-09-27 | 2024-05-08 | 国立大学法人広島大学 | プラスチック粒子の検出方法およびプラスチック粒子の検出キット |
CN110726710A (zh) * | 2019-10-28 | 2020-01-24 | 山东师范大学 | 基于Au-Se界面的SERS传感器用于超灵敏高保真生物分子定量检测 |
US11785734B2 (en) * | 2020-05-04 | 2023-10-10 | Panduit Corp. | Data center cabinet and top caps for a data center cabinet |
WO2022056313A2 (en) | 2020-09-11 | 2022-03-17 | Glympse Bio, Inc. | Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment |
US11796517B2 (en) | 2021-11-09 | 2023-10-24 | Saudi Arabian Oil Company | Multifunctional magnetic tags for mud logging |
US11999855B2 (en) | 2021-12-13 | 2024-06-04 | Saudi Arabian Oil Company | Fluorescent dye molecules having hydrophilicity and hydrophobicity for tracer applications |
US11725139B2 (en) | 2021-12-13 | 2023-08-15 | Saudi Arabian Oil Company | Manipulating hydrophilicity of conventional dye molecules for water tracer applications |
US12000278B2 (en) | 2021-12-16 | 2024-06-04 | Saudi Arabian Oil Company | Determining oil and water production rates in multiple production zones from a single production well |
CN114384032B (zh) * | 2022-01-17 | 2023-07-14 | 云南大学 | 诺如病毒检测探针和非诊断目的检测诺如病毒的方法 |
CN115746091A (zh) * | 2022-07-29 | 2023-03-07 | 胶原蛋白(武汉)生物科技有限公司 | 一种高稳定性的胶原蛋白靶向sers多肽探针及其在肝纤维化诊断中的应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5306403A (en) * | 1992-08-24 | 1994-04-26 | Martin Marietta Energy Systems, Inc. | Raman-based system for DNA sequencing-mapping and other separations |
JP2005501545A (ja) * | 2001-09-04 | 2005-01-20 | イエダ リサーチ アンド ディベロップメント カンパニー リミテッド | カスパーゼ結合タンパク質、その調製物および使用 |
US8697029B2 (en) * | 2002-04-18 | 2014-04-15 | The Regents Of The University Of Michigan | Modulated physical and chemical sensors |
US7429472B2 (en) * | 2003-01-31 | 2008-09-30 | Promega Corporation | Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule |
US20050148100A1 (en) * | 2003-12-30 | 2005-07-07 | Intel Corporation | Methods and devices for using Raman-active probe constructs to assay biological samples |
US7425436B2 (en) * | 2004-07-30 | 2008-09-16 | Promega Corporation | Covalent tethering of functional groups to proteins and substrates therefor |
ATE478559T1 (de) * | 2006-05-03 | 2010-09-15 | Univ California | Nachweis von protease und protease-aktivität mithilfe einer einzel-nanosteigerungs-sers-sonde |
CN104155282A (zh) * | 2007-11-02 | 2014-11-19 | 加利福尼亚大学董事会 | 纳米等离子体激元共振器 |
AU2008346794A1 (en) * | 2007-12-31 | 2009-07-16 | The Regents Of The University Of California | SERS-based, single step, real-time detection of protein kinase and/or phosphatase activity |
-
2007
- 2007-05-02 AT AT07835744T patent/ATE478559T1/de not_active IP Right Cessation
- 2007-05-02 US US12/299,284 patent/US8361932B2/en active Active
- 2007-05-02 EP EP20070835744 patent/EP2019587B1/de not_active Not-in-force
- 2007-05-02 CN CN200780024900.8A patent/CN101484002B/zh not_active Expired - Fee Related
- 2007-05-02 DE DE200760008716 patent/DE602007008716D1/de active Active
- 2007-05-02 WO PCT/US2007/010722 patent/WO2008018933A2/en active Application Filing
- 2007-05-02 JP JP2009509709A patent/JP2009535060A/ja active Pending
- 2007-05-02 CA CA 2679707 patent/CA2679707A1/en not_active Abandoned
- 2007-05-02 KR KR20087029616A patent/KR20090009302A/ko not_active Application Discontinuation
- 2007-05-02 AU AU2007282164A patent/AU2007282164A1/en not_active Abandoned
-
2013
- 2013-01-28 US US13/752,069 patent/US9145575B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP2019587A2 (de) | 2009-02-04 |
US8361932B2 (en) | 2013-01-29 |
WO2008018933A2 (en) | 2008-02-14 |
DE602007008716D1 (de) | 2010-10-07 |
CN101484002B (zh) | 2014-04-30 |
US20100048412A1 (en) | 2010-02-25 |
JP2009535060A (ja) | 2009-10-01 |
WO2008018933A3 (en) | 2008-10-09 |
KR20090009302A (ko) | 2009-01-22 |
US20140011705A1 (en) | 2014-01-09 |
EP2019587B1 (de) | 2010-08-25 |
CN101484002A (zh) | 2009-07-15 |
US9145575B2 (en) | 2015-09-29 |
AU2007282164A1 (en) | 2008-02-14 |
CA2679707A1 (en) | 2008-02-14 |
EP2019587A4 (de) | 2009-06-10 |
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