ATE452147T1 - Antikörper mit korrigierten cdr - Google Patents
Antikörper mit korrigierten cdrInfo
- Publication number
- ATE452147T1 ATE452147T1 AT05723312T AT05723312T ATE452147T1 AT E452147 T1 ATE452147 T1 AT E452147T1 AT 05723312 T AT05723312 T AT 05723312T AT 05723312 T AT05723312 T AT 05723312T AT E452147 T1 ATE452147 T1 AT E452147T1
- Authority
- AT
- Austria
- Prior art keywords
- antibodies
- cdr
- corrected
- selection
- present application
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
- C07K16/464—Igs containing CDR-residues from one specie grafted between FR-residues from another
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
- C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54584004P | 2004-02-19 | 2004-02-19 | |
| PCT/US2005/005270 WO2005080432A2 (en) | 2004-02-19 | 2005-02-18 | Cdr-repaired antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE452147T1 true ATE452147T1 (de) | 2010-01-15 |
Family
ID=34886204
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05723312T ATE452147T1 (de) | 2004-02-19 | 2005-02-18 | Antikörper mit korrigierten cdr |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20060122377A1 (de) |
| EP (3) | EP1716181B1 (de) |
| AT (1) | ATE452147T1 (de) |
| AU (1) | AU2005214382B2 (de) |
| CA (1) | CA2555820C (de) |
| DE (1) | DE602005018325D1 (de) |
| DK (1) | DK1716181T3 (de) |
| ES (1) | ES2337473T3 (de) |
| WO (1) | WO2005080432A2 (de) |
Families Citing this family (37)
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| WO2003105782A2 (en) | 2002-06-17 | 2003-12-24 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Specificity grafting of a murine antibody onto a human framework |
| AU2003248744C1 (en) * | 2002-06-28 | 2009-12-24 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Humanized anti-TAG-72 CC49 for diagnosis and therapy of human tumors |
| PT1517921E (pt) * | 2002-06-28 | 2006-09-29 | Domantis Ltd | Ligandos duplamente especificos com semi-vida no soro aumentada |
| CN104013957B (zh) | 2003-12-23 | 2016-06-29 | 泰勒公司 | 用新的抗il13单克隆抗体治疗癌症 |
| CA2619654A1 (en) | 2005-08-24 | 2007-03-01 | Cell Matrix | Combination therapies for inhibiting integrin-extracellular matrix interactions |
-
2005
- 2005-02-18 DK DK05723312.4T patent/DK1716181T3/da active
- 2005-02-18 US US11/061,841 patent/US20060122377A1/en not_active Abandoned
- 2005-02-18 DE DE602005018325T patent/DE602005018325D1/de active Active
- 2005-02-18 AT AT05723312T patent/ATE452147T1/de not_active IP Right Cessation
- 2005-02-18 WO PCT/US2005/005270 patent/WO2005080432A2/en active Application Filing
- 2005-02-18 CA CA2555820A patent/CA2555820C/en active Active
- 2005-02-18 EP EP05723312A patent/EP1716181B1/de not_active Revoked
- 2005-02-18 AU AU2005214382A patent/AU2005214382B2/en active Active
- 2005-02-18 ES ES05723312T patent/ES2337473T3/es active Active
- 2005-02-18 EP EP19195877.6A patent/EP3653641A1/de not_active Withdrawn
- 2005-02-18 EP EP09179091A patent/EP2168986A3/de not_active Withdrawn
-
2010
- 2010-11-16 US US12/947,714 patent/US8580928B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005214382A1 (en) | 2005-09-01 |
| DE602005018325D1 (de) | 2010-01-28 |
| US20110237779A1 (en) | 2011-09-29 |
| WO2005080432A3 (en) | 2006-02-16 |
| WO2005080432A2 (en) | 2005-09-01 |
| EP3653641A1 (de) | 2020-05-20 |
| US8580928B2 (en) | 2013-11-12 |
| EP2168986A3 (de) | 2010-07-28 |
| DK1716181T3 (da) | 2010-03-01 |
| EP2168986A2 (de) | 2010-03-31 |
| EP1716181B1 (de) | 2009-12-16 |
| ES2337473T3 (es) | 2010-04-26 |
| CA2555820C (en) | 2016-01-19 |
| CA2555820A1 (en) | 2005-09-01 |
| AU2005214382B2 (en) | 2011-08-04 |
| US20060122377A1 (en) | 2006-06-08 |
| EP1716181A2 (de) | 2006-11-02 |
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