ATE416761T1 - Prävention und behandlung von durch entzündung ausgelöstem und/oder immunvermitteltem knochenschwund - Google Patents
Prävention und behandlung von durch entzündung ausgelöstem und/oder immunvermitteltem knochenschwundInfo
- Publication number
- ATE416761T1 ATE416761T1 AT04765458T AT04765458T ATE416761T1 AT E416761 T1 ATE416761 T1 AT E416761T1 AT 04765458 T AT04765458 T AT 04765458T AT 04765458 T AT04765458 T AT 04765458T AT E416761 T1 ATE416761 T1 AT E416761T1
- Authority
- AT
- Austria
- Prior art keywords
- immune
- prevention
- treatment
- inflammatory
- bone loss
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50471703P | 2003-09-22 | 2003-09-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE416761T1 true ATE416761T1 (de) | 2008-12-15 |
Family
ID=34375537
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04765458T ATE416761T1 (de) | 2003-09-22 | 2004-09-21 | Prävention und behandlung von durch entzündung ausgelöstem und/oder immunvermitteltem knochenschwund |
Country Status (15)
Country | Link |
---|---|
US (2) | US20100087413A1 (de) |
EP (2) | EP2036548A1 (de) |
JP (1) | JP2007533625A (de) |
AT (1) | ATE416761T1 (de) |
AU (1) | AU2004273610B2 (de) |
CA (1) | CA2539741A1 (de) |
CY (1) | CY1111246T1 (de) |
DE (1) | DE602004018338D1 (de) |
DK (1) | DK1663185T3 (de) |
ES (1) | ES2317029T3 (de) |
NZ (1) | NZ546062A (de) |
PL (1) | PL1663185T3 (de) |
PT (1) | PT1663185E (de) |
SI (1) | SI1663185T1 (de) |
WO (1) | WO2005027882A1 (de) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2579089A1 (en) * | 2004-08-30 | 2006-03-09 | Government Of The United States Of America As Represented By The Secreta Ry Department Of Health And Human Services | Inhibition of viruses using rnase h inhibitors |
WO2006105127A2 (en) | 2005-03-31 | 2006-10-05 | Takeda San Diego, Inc. | Hydroxysteroid dehydrogenase inhibitors |
DE102005026231A1 (de) * | 2005-06-07 | 2006-12-14 | Origenis Ag | Peptid-Deformylase (PDF) Inhibitoren 3 |
ES2399976T3 (es) * | 2006-06-01 | 2013-04-04 | Novagali Pharma S.A. | Uso de profármacos para la administración intravítrea ocular |
MX2009000117A (es) | 2006-07-06 | 2009-01-23 | Glaxo Group Ltd | N-fenilmetil-5-oxo-prolin-2-amidas sustituidas como antagonistas de receptores p2x7 y sus metodos de uso. |
WO2008055945A1 (en) | 2006-11-09 | 2008-05-15 | Probiodrug Ag | 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases |
GB0706072D0 (en) * | 2007-03-28 | 2007-05-09 | Sterix Ltd | Compound |
KR101022809B1 (ko) * | 2008-02-05 | 2011-03-17 | 재단법인서울대학교산학협력재단 | 면역조절에 의한 캔디다알비칸스 기인성 질환의 치료 |
EP2336109A4 (de) * | 2008-09-25 | 2012-05-02 | Shionogi & Co | Neues pyrrolinonderivat und medizinische zusammensetzung damit |
US20110319416A1 (en) * | 2009-01-28 | 2011-12-29 | Emory University | Subunit Selective NMDA Receptor Antagonists For The Treatment Of Neurological Conditions |
CU24130B1 (es) | 2009-12-22 | 2015-09-29 | Novartis Ag | Isoquinolinonas y quinazolinonas sustituidas |
US8440693B2 (en) | 2009-12-22 | 2013-05-14 | Novartis Ag | Substituted isoquinolinones and quinazolinones |
JP2012041291A (ja) * | 2010-08-18 | 2012-03-01 | Institute Of Physical & Chemical Research | 歯周病の治療または予防剤 |
ITRM20100614A1 (it) * | 2010-11-24 | 2012-05-25 | D M G Italia S R L | Preparazioni farmaceutiche dell acido 18 beta glicirretico e/o di suoi derivati per infiltrazioni intrarticolari per il trattamento delle artropatie infiammatorie |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
ES2885523T3 (es) | 2011-11-23 | 2021-12-14 | Therapeuticsmd Inc | Formulaciones y terapias de reposición hormonal de combinación naturales |
US9365576B2 (en) | 2012-05-24 | 2016-06-14 | Novartis Ag | Pyrrolopyrrolidinone compounds |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
WO2014115077A1 (en) | 2013-01-22 | 2014-07-31 | Novartis Ag | Substituted purinone compounds |
US9556180B2 (en) | 2013-01-22 | 2017-01-31 | Novartis Ag | Pyrazolo[3,4-d]pyrimidinone compounds as inhibitors of the P53/MDM2 interaction |
MX2015016344A (es) | 2013-05-27 | 2016-03-01 | Novartis Ag | Derivados de imidazo-pirrolidinona y su uso en el tratamiento de enfermedades. |
PL3004112T3 (pl) | 2013-05-28 | 2018-02-28 | Novartis Ag | Pochodne pirazolo-pirolidyn-4-onu oraz ich zastosowanie w leczeniu choroby |
MX2015016421A (es) | 2013-05-28 | 2016-03-03 | Novartis Ag | Derivados de pirazolo-pirrolidin-4-ona como inhibidores de bet y su uso en el tratamiento de enfermedades. |
EP3071571A1 (de) | 2013-11-21 | 2016-09-28 | Novartis AG | Pyrrolopyrrolonderivate und deren verwendung als bet-inhibitoren |
CN104873520A (zh) * | 2014-02-27 | 2015-09-02 | 天津药物研究院 | 一种11β-羟基类固醇脱氢酶抑制剂、药用组合物及其用途 |
CN104873521A (zh) * | 2014-02-27 | 2015-09-02 | 天津药物研究院 | 一种11β-羟基类固醇脱氢酶抑制剂、药用组合物及其应用 |
AU2015264003A1 (en) | 2014-05-22 | 2016-11-17 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
WO2017173071A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
WO2019060051A1 (en) | 2017-08-04 | 2019-03-28 | Ardelyx, Inc. | GLYCYRRHETINIC ACID DERIVATIVES FOR THE TREATMENT OF HYPERKALIEMIA |
GB201805100D0 (en) * | 2018-03-28 | 2018-05-09 | Benevolentai Bio Ltd | Treatment of sarcopenic diseases |
WO2020163642A1 (en) * | 2019-02-07 | 2020-08-13 | Ardelyx, Inc. | Glycyrrhetinic acid derivatives for use in treating hyperkalemia |
Family Cites Families (19)
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US3262851A (en) * | 1958-06-26 | 1966-07-26 | Biorex Laboratories Ltd | Pharmacological compositions containing glycyrrhetinic acid derivative |
DE2050072C3 (de) * | 1970-10-12 | 1975-01-30 | Inverni Della Beffa S.P.A., Mailand (Italien) | Aluminium-tri-3-acetyl-18 betaglycyrrthetinat, Verfahren zu seiner Herstellung und dieses enthaltende pharmazeutische Zubereitungen |
US3934027A (en) * | 1973-05-03 | 1976-01-20 | Pfizer Inc. | 18β-Glycyrrhetinic acid amides useful as antiulcer agents |
EP0496520A1 (de) * | 1991-01-22 | 1992-07-29 | Merck & Co. Inc. | Knochenaktive Verbindungen |
GB2261672A (en) * | 1991-11-18 | 1993-05-26 | Michael Braden | The use of biomaterials for tissue repair |
JPH07291857A (ja) * | 1994-04-27 | 1995-11-07 | Suntory Ltd | グリチルレチン酸化合物を有効成分とする骨疾患の予防及び治療剤 |
DE19951970A1 (de) * | 1999-10-28 | 2001-05-03 | Bionetworks Gmbh | Arzneimittel für die Toleranzinduktion |
US20050048007A1 (en) * | 2000-11-02 | 2005-03-03 | Inobys Ltd. | Plaque reducing composition |
GB0105772D0 (en) * | 2001-03-08 | 2001-04-25 | Sterix Ltd | Use |
GB0107383D0 (en) * | 2001-03-23 | 2001-05-16 | Univ Edinburgh | Lipid profile modulation |
CN1649855A (zh) | 2001-11-22 | 2005-08-03 | 比奥维特罗姆股份公司 | 11-β-羟基类固醇脱氢酶1型抑制剂 |
AU2002353718B2 (en) | 2001-11-22 | 2007-05-10 | Biovitrum Ab | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 |
WO2003065983A2 (en) | 2002-02-01 | 2003-08-14 | Merck & Co., Inc. | 11-beta-hydroxysteroid dehydrogenase 1 inhibitors useful for the treatment of diabetes, obesity and dyslipidemia |
AR040241A1 (es) | 2002-06-10 | 2005-03-23 | Merck & Co Inc | Inhibidores de la 11-beta-hidroxiesteroide deshidrogrenasa 1 para el tratamiento de la diabetes obesidad y dislipidemia |
EP1546183A4 (de) | 2002-09-23 | 2008-06-18 | Du Pont | Isolierung und verwendung von ryanodinrezeptoren |
JO2397B1 (en) | 2002-12-20 | 2007-06-17 | ميرك شارب اند دوم كوربوريشن | Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors |
WO2004056744A1 (en) | 2002-12-23 | 2004-07-08 | Janssen Pharmaceutica N.V. | Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors |
US20030148349A1 (en) * | 2003-01-03 | 2003-08-07 | Shyam Ramakrishnan | Regulation of human 11 beta-hydroxysteroid dehydrogenase 1-like enzyme |
TW200503994A (en) | 2003-01-24 | 2005-02-01 | Novartis Ag | Organic compounds |
-
2004
- 2004-09-21 EP EP08169750A patent/EP2036548A1/de not_active Withdrawn
- 2004-09-21 JP JP2006527336A patent/JP2007533625A/ja active Pending
- 2004-09-21 WO PCT/EP2004/010582 patent/WO2005027882A1/en active Search and Examination
- 2004-09-21 ES ES04765458T patent/ES2317029T3/es active Active
- 2004-09-21 AT AT04765458T patent/ATE416761T1/de active
- 2004-09-21 PT PT04765458T patent/PT1663185E/pt unknown
- 2004-09-21 DE DE602004018338T patent/DE602004018338D1/de active Active
- 2004-09-21 DK DK04765458T patent/DK1663185T3/da active
- 2004-09-21 EP EP04765458A patent/EP1663185B1/de not_active Not-in-force
- 2004-09-21 AU AU2004273610A patent/AU2004273610B2/en not_active Ceased
- 2004-09-21 PL PL04765458T patent/PL1663185T3/pl unknown
- 2004-09-21 CA CA002539741A patent/CA2539741A1/en not_active Abandoned
- 2004-09-21 NZ NZ546062A patent/NZ546062A/en unknown
- 2004-09-21 SI SI200431023T patent/SI1663185T1/sl unknown
- 2004-09-21 US US10/572,795 patent/US20100087413A1/en not_active Abandoned
-
2009
- 2009-03-06 CY CY20091100259T patent/CY1111246T1/el unknown
-
2011
- 2011-05-11 US US13/105,434 patent/US20110275584A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20110275584A1 (en) | 2011-11-10 |
AU2004273610B2 (en) | 2010-07-01 |
AU2004273610A1 (en) | 2005-03-31 |
US20100087413A1 (en) | 2010-04-08 |
CY1111246T1 (el) | 2015-06-11 |
ES2317029T3 (es) | 2009-04-16 |
DE602004018338D1 (de) | 2009-01-22 |
EP1663185B1 (de) | 2008-12-10 |
SI1663185T1 (sl) | 2009-04-30 |
CA2539741A1 (en) | 2005-03-31 |
PT1663185E (pt) | 2009-02-16 |
EP2036548A1 (de) | 2009-03-18 |
JP2007533625A (ja) | 2007-11-22 |
DK1663185T3 (da) | 2009-04-06 |
PL1663185T3 (pl) | 2009-06-30 |
WO2005027882A1 (en) | 2005-03-31 |
EP1663185A1 (de) | 2006-06-07 |
NZ546062A (en) | 2009-09-25 |
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