ATE414519T1 - Kombination aus einem nmda-antagonist und acetylcholinesterase-hemmern zur behandlung der alzheimer-krankheit - Google Patents
Kombination aus einem nmda-antagonist und acetylcholinesterase-hemmern zur behandlung der alzheimer-krankheitInfo
- Publication number
- ATE414519T1 ATE414519T1 AT03724895T AT03724895T ATE414519T1 AT E414519 T1 ATE414519 T1 AT E414519T1 AT 03724895 T AT03724895 T AT 03724895T AT 03724895 T AT03724895 T AT 03724895T AT E414519 T1 ATE414519 T1 AT E414519T1
- Authority
- AT
- Austria
- Prior art keywords
- alzheimer
- disease
- treatment
- combination
- acetylcholinesterase inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38446702P | 2002-05-31 | 2002-05-31 | |
DKPA200200844 | 2002-05-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE414519T1 true ATE414519T1 (de) | 2008-12-15 |
Family
ID=29713304
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03724895T ATE414519T1 (de) | 2002-05-31 | 2003-05-22 | Kombination aus einem nmda-antagonist und acetylcholinesterase-hemmern zur behandlung der alzheimer-krankheit |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP1509232B1 (de) |
JP (1) | JP2005528431A (de) |
AT (1) | ATE414519T1 (de) |
AU (1) | AU2003227516B2 (de) |
BR (1) | BR0311375A (de) |
CY (1) | CY1108725T1 (de) |
DE (1) | DE60324788D1 (de) |
DK (1) | DK1509232T3 (de) |
ES (1) | ES2314200T3 (de) |
IL (1) | IL165255A0 (de) |
MX (1) | MXPA04011762A (de) |
NO (1) | NO332754B1 (de) |
NZ (1) | NZ536603A (de) |
PL (1) | PL373903A1 (de) |
PT (1) | PT1509232E (de) |
SI (1) | SI1509232T1 (de) |
WO (1) | WO2003101458A1 (de) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA04006900A (es) * | 2002-10-24 | 2004-10-15 | Merz Pharma Gmbh & Co Kgaa | Politerapia que utiliza derivados de 1-aminociclohexano e inhibidores de acetilcolinesterasa. |
US20060020042A1 (en) * | 2004-01-05 | 2006-01-26 | Forest Laboratories, Inc. | Memantine for the treatment of mild and mild to moderate Alzheimer's disease |
EP1708707A1 (de) * | 2004-01-22 | 2006-10-11 | Neurosearch A/S | Pharmazeutische zusammensetzung mit einem monoamin-neurotransmitter-wiederaufnahmehemmer und einem n-methyl-d-aspartat (nmda)-rezeptorantagonisten |
TW200531680A (en) * | 2004-03-03 | 2005-10-01 | Merz Pharma Gmbh & Co Kgaa | Therapy using 1-aminocyclohexane derivatives for the treatment of behavioral disorders associated with alzheimer's disease |
WO2005092009A2 (en) * | 2004-03-19 | 2005-10-06 | Axonyx, Inc. | Acetylcholinesterase inhibitors and n-methyl-d-aspartate antagonists useful in the treatment of cognitive disorders |
EP1827385B1 (de) * | 2004-11-23 | 2013-03-27 | Adamas Pharmaceuticals, Inc. | Pharmazeutische zusammensetzung enthaltend memantin in verzögerter freisetzungs-form zur behandlung von dementia |
US7619007B2 (en) | 2004-11-23 | 2009-11-17 | Adamas Pharmaceuticals, Inc. | Method and composition for administering an NMDA receptor antagonist to a subject |
JP5666087B2 (ja) | 2005-04-06 | 2015-02-12 | アダマス・ファーマシューティカルズ・インコーポレーテッド | Cns関連疾患の治療のための方法及び組成物 |
EP1878444B1 (de) * | 2005-04-28 | 2015-09-09 | Eisai R&D Management Co., Ltd. | Zusammensetzung mit einem arzneimittel gegen demenz |
TWI389709B (zh) * | 2005-12-01 | 2013-03-21 | Novartis Ag | 經皮治療系統 |
WO2008055945A1 (en) | 2006-11-09 | 2008-05-15 | Probiodrug Ag | 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases |
WO2008065141A1 (en) | 2006-11-30 | 2008-06-05 | Probiodrug Ag | Novel inhibitors of glutaminyl cyclase |
ZA200905537B (en) | 2007-03-01 | 2010-10-27 | Probiodrug Ag | New use of glutaminyl cyclase inhibitors |
JP5667440B2 (ja) | 2007-04-18 | 2015-02-12 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのチオ尿素誘導体 |
MX2012002993A (es) | 2009-09-11 | 2012-04-19 | Probiodrug Ag | Derivados heterociclicos como inhibidores de ciclasa glutaminilo. |
CA2782556C (en) | 2009-12-02 | 2018-03-27 | Adamas Pharmaceuticals, Inc. | Amantadine compositions and methods of use |
CA2789014C (en) | 2010-02-09 | 2019-01-15 | Michela Gallagher | Methods and compositions for improving cognitive function |
JP6026284B2 (ja) | 2010-03-03 | 2016-11-16 | プロビオドルグ エージー | グルタミニルシクラーゼの阻害剤 |
MX2012010470A (es) | 2010-03-10 | 2012-10-09 | Probiodrug Ag | Inhibidores heterociclicos d ciclasa de glutaminilo (qc, ec .3 2. 5). |
US8541596B2 (en) | 2010-04-21 | 2013-09-24 | Probiodrug Ag | Inhibitors |
AU2011276036B2 (en) | 2010-07-05 | 2014-05-22 | Gambro Lundia Ab | An ambulatory ultrafiltration device, related methods and a computer program product |
TR201007110A2 (tr) | 2010-08-25 | 2012-03-21 | Bi̇lgi̇ç Mahmut | Sinerjik etki gösteren kombinasyonlar |
WO2012048871A1 (en) | 2010-10-12 | 2012-04-19 | Merz Pharma Gmbh & Co. Kgaa | Memantine for improving cognitive performance in subjects |
WO2012123563A1 (en) | 2011-03-16 | 2012-09-20 | Probiodrug Ag | Benz imidazole derivatives as inhibitors of glutaminyl cyclase |
FR2983732B1 (fr) * | 2011-12-09 | 2013-11-22 | Servier Lab | Nouvelle association entre le 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}pharmaceutiques qui la contiennent |
WO2013160728A1 (en) * | 2012-04-26 | 2013-10-31 | Alma Mater Studiorum - Universita' Di Bologna | Dual targeting compounds for the treatment of alzheimer's disease |
WO2014035355A1 (en) * | 2012-08-31 | 2014-03-06 | Mahmut Bilgic | Pharmaceutical combination comprising idebenone and memantine |
WO2014055047A1 (en) * | 2012-08-31 | 2014-04-10 | Mahmut Bilgic | Combination of idebenone and donezepil |
JP6440625B2 (ja) | 2012-11-14 | 2018-12-19 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 精神***病を処置するための方法および組成物 |
AP2015008498A0 (en) * | 2012-12-13 | 2015-05-31 | Lundbeck & Co As H | Compositions comprising vortioxetine and donepezil |
WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
CA2904767C (en) | 2013-03-15 | 2022-06-21 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
WO2014204933A1 (en) | 2013-06-17 | 2014-12-24 | Adamas Pharmaceuticals, Inc. | Amantadine compositions and methods of use |
WO2016191288A1 (en) | 2015-05-22 | 2016-12-01 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
MA45002B1 (fr) * | 2016-05-18 | 2020-10-28 | Suven Life Sciences Ltd | Triple combinaison d'antagonistes purs du récepteurs 5-ht6, d'inhibiteurs de l'acétylcholinestérase et d'antagonistes du récepteur nmda |
GB201614834D0 (en) * | 2016-09-01 | 2016-10-19 | Wista Lab Ltd | Treatment of dementia |
KR101938872B1 (ko) * | 2016-09-30 | 2019-01-16 | 주식회사 바이오파마티스 | 도네페질 또는 그의 약학적으로 허용 가능한 염 및 메만틴 또는 그의 약학적으로 허용 가능한 염을 함유하는 치매 및 인지기능 장애 예방 또는 치료용 약학 조성물 및 이의 제조방법 |
US20190269627A1 (en) * | 2016-10-28 | 2019-09-05 | Chase Pharmaceuticals Corporation | Memantine combinations and use |
TR201619184A2 (tr) | 2016-12-22 | 2018-07-23 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Donepezi̇l ve memanti̇n i̇çeren kapsül bi̇leşi̇mleri̇ |
EP3461819B1 (de) | 2017-09-29 | 2020-05-27 | Probiodrug AG | Hemmer der glutaminylcyclase |
PT3843702T (pt) | 2019-05-31 | 2023-10-13 | Tecnimede Soc Tecnico Medicinal Lda | Combinação de dose fixa de libertação imediata de memantina e donepezilo |
-
2003
- 2003-05-22 MX MXPA04011762A patent/MXPA04011762A/es active IP Right Grant
- 2003-05-22 JP JP2004508815A patent/JP2005528431A/ja active Pending
- 2003-05-22 ES ES03724895T patent/ES2314200T3/es not_active Expired - Lifetime
- 2003-05-22 SI SI200331469T patent/SI1509232T1/sl unknown
- 2003-05-22 PT PT03724895T patent/PT1509232E/pt unknown
- 2003-05-22 DE DE60324788T patent/DE60324788D1/de not_active Expired - Lifetime
- 2003-05-22 PL PL03373903A patent/PL373903A1/xx not_active Application Discontinuation
- 2003-05-22 IL IL16525503A patent/IL165255A0/xx unknown
- 2003-05-22 DK DK03724895T patent/DK1509232T3/da active
- 2003-05-22 BR BR0311375-2A patent/BR0311375A/pt not_active IP Right Cessation
- 2003-05-22 NZ NZ536603A patent/NZ536603A/en not_active IP Right Cessation
- 2003-05-22 AT AT03724895T patent/ATE414519T1/de active
- 2003-05-22 AU AU2003227516A patent/AU2003227516B2/en not_active Ceased
- 2003-05-22 WO PCT/DK2003/000342 patent/WO2003101458A1/en active Application Filing
- 2003-05-22 EP EP03724895A patent/EP1509232B1/de not_active Revoked
-
2004
- 2004-12-13 NO NO20045434A patent/NO332754B1/no not_active IP Right Cessation
-
2009
- 2009-01-21 CY CY20091100080T patent/CY1108725T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
NO20045434L (no) | 2004-12-13 |
DE60324788D1 (de) | 2009-01-02 |
CY1108725T1 (el) | 2014-04-09 |
EP1509232B1 (de) | 2008-11-19 |
SI1509232T1 (sl) | 2009-04-30 |
NZ536603A (en) | 2007-06-29 |
DK1509232T3 (da) | 2009-02-23 |
WO2003101458A1 (en) | 2003-12-11 |
MXPA04011762A (es) | 2005-03-31 |
AU2003227516A1 (en) | 2003-12-19 |
IL165255A0 (en) | 2005-12-18 |
BR0311375A (pt) | 2005-03-15 |
ES2314200T3 (es) | 2009-03-16 |
PL373903A1 (en) | 2005-09-19 |
JP2005528431A (ja) | 2005-09-22 |
NO332754B1 (no) | 2013-01-07 |
AU2003227516B2 (en) | 2008-03-20 |
EP1509232A1 (de) | 2005-03-02 |
PT1509232E (pt) | 2009-01-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE414519T1 (de) | Kombination aus einem nmda-antagonist und acetylcholinesterase-hemmern zur behandlung der alzheimer-krankheit | |
ATE443043T1 (de) | Phenylcarboxamide als beta-sekretase-hemmer zur behandlung von alzheimer | |
BR0308243A (pt) | Composto, formulação farmacêutica, e, métodos de tratar diabetes, doença de alzheimer, e de inibir gsk-3 em um mamìfero | |
ATE430555T1 (de) | Pharmazeutische zusammensetzungen zur behandlung von asthma | |
MA25809A1 (fr) | Derives d'arylmethylamine pour usage comme inhibiteurs de tryptase | |
GEP20053600B (en) | 3-(4-Amidopyrrol-2-Ylmethlidene)-2- Indolinone Derivatives as Protein Kinase Inhibitors | |
ATE371656T1 (de) | Heteroaryl-pyrimidinderivate als jak-inhibitoren | |
ATE416761T1 (de) | Prävention und behandlung von durch entzündung ausgelöstem und/oder immunvermitteltem knochenschwund | |
BR0316350A (pt) | Diaminotriazóis úteis como inibidores de proteìna cinases | |
ATE512163T1 (de) | Verabreichung von mitteln zur behandlung von entzündungen | |
ATE334668T1 (de) | Pharmazeutische zusammensetzung zur behandlung von neurologischen und neuropsychiatrischen erkrankungen | |
MXPA04002167A (es) | Inhibidores de la 17 beta-hidroxiesteroide deshidrogenasa tipo 3 para el tratamiento de enfermedades androgeno-dependientes. | |
GB0223040D0 (en) | Therapeutic compounds | |
CY1106927T1 (el) | Φαρμακευτικη συνθεση ενος pde4 ή pde3/4 αναστολεα και ανταγωνιστη υποδοχεα ισταμινης | |
EA200201276A1 (ru) | Производные арилметиламина для использования в качестве ингибиторов триптазы | |
ATE357438T1 (de) | 1,2,4-triaminobenzolderivate zur behandlung von erkrankungen des zentralnervensystems | |
IS6087A (is) | N-(2-fenýl-4-amínó-bútýl)-1-naftamíð sem virka á móti taugakínín-1 viðtaka | |
DE60134735D1 (de) | Neue neurokinin-antagonisten zum gebrauch als arzneimittel | |
DE69917005D1 (de) | Substituierte pyrrolobenzimidazolderivate zur entzündungshemmung | |
ATE425756T1 (de) | Verwendung von carbamazepinderivaten zur behandlung von agitatio in demenspatienten | |
ATE308513T1 (de) | Naphthamid-neurokinin antagonisten zur verwendung als medikamente | |
ATE420860T1 (de) | N-substituierte amide als nk1 rezeptor antagonisten | |
NO20033634L (no) | GLyT-1-inhibitorer | |
EA200401617A1 (ru) | Комбинация nmda-антагониста и ингибиторов ацетилхолинэстеразы для лечения болезни альцгеймера | |
DE60122764D1 (de) | Verwendung von cortisol-sequestriermitteln zur behandlung von hypercortisolaemie-verwandten erkrankungen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1509232 Country of ref document: EP |