US20060148725A1
(en)
*
|
2001-12-21 |
2006-07-06 |
The Miriam Hospital |
Selective 11beta HSD inhibitors and methods of use thereof
|
EP1587574A4
(en)
*
|
2001-12-21 |
2009-03-18 |
Rhode Island Hospital |
11b-HSD SELECTIVE INHIBITORS AND METHODS OF USE
|
DE60317631T2
(de)
*
|
2002-02-01 |
2008-09-25 |
Merck & Co., Inc. |
11-beta-hydroxysteroid-dehydrogenase-1-hemmer zur behandlung von diabetes, adipositas und dyslipidämie
|
JO2397B1
(en)
*
|
2002-12-20 |
2007-06-17 |
ميرك شارب اند دوم كوربوريشن |
Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors
|
WO2004065380A1
(en)
|
2003-01-14 |
2004-08-05 |
Arena Pharmaceuticals Inc. |
1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prpphylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
|
EP1624876A2
(en)
*
|
2003-04-29 |
2006-02-15 |
The Miriam Hospital |
Selective testicular 11beta-hsd inhibitors and methods of use thereof
|
WO2004110375A2
(en)
*
|
2003-06-06 |
2004-12-23 |
Merck & Co., Inc. |
Combination therapy for the treatment of diabetes
|
GB0315111D0
(en)
|
2003-06-27 |
2003-07-30 |
Cancer Rec Tech Ltd |
Substituted 5-membered ring compounds and their use
|
EP2036548A1
(en)
|
2003-09-22 |
2009-03-18 |
onepharm Research & Development GmbH |
Prevention and treatment of inflammation-induced and/or immune-mediated bone loss
|
AU2004286836A1
(en)
|
2003-10-28 |
2005-05-19 |
Amgen Inc. |
Triazole compounds and uses related thereto
|
US20050137209A1
(en)
*
|
2003-12-18 |
2005-06-23 |
Agy Therapeutics, Inc. |
Treatment of neurologic disorders with inhibitors of 11beta-HSD1
|
US7745630B2
(en)
|
2003-12-22 |
2010-06-29 |
Justin Stephen Bryans |
Triazolyl piperidine arginine vasopressin receptor modulators
|
EP1711477A4
(en)
*
|
2004-01-26 |
2009-06-10 |
Merck & Co Inc |
NOVEL CRYSTALLINE FORMS OF AN INHIBITOR OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1
|
US7354938B2
(en)
|
2004-03-23 |
2008-04-08 |
Amgen Inc. |
Pyrazole compounds and uses related thereto
|
AU2005230864A1
(en)
|
2004-03-29 |
2005-10-20 |
Merck Sharp & Dohme Corp. |
Diaryltriazoles as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
|
US20050261302A1
(en)
*
|
2004-04-29 |
2005-11-24 |
Hoff Ethan D |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their therapeutic application
|
TWI350168B
(en)
|
2004-05-07 |
2011-10-11 |
Incyte Corp |
Amido compounds and their use as pharmaceuticals
|
AU2005240784C1
(en)
|
2004-05-07 |
2011-12-22 |
Janssen Pharmaceutica N.V. |
Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
|
US7687644B2
(en)
*
|
2004-05-07 |
2010-03-30 |
Janssen Pharmaceutica Nv |
Adamantyl pyrrolidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
|
WO2005121132A1
(ja)
*
|
2004-06-11 |
2005-12-22 |
Shionogi & Co., Ltd. |
抗hcv作用を有する縮合ヘテロ環化合物
|
US20060025445A1
(en)
*
|
2004-08-02 |
2006-02-02 |
Xiang Jason S |
11-Beta HSD1 inhibitors
|
GB0418877D0
(en)
*
|
2004-08-24 |
2004-09-29 |
Univ Edinburgh |
Heart
|
WO2006024628A1
(en)
|
2004-08-30 |
2006-03-09 |
Janssen Pharmaceutica N.V. |
Tricyclic lactam derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
|
DE602005017159D1
(de)
|
2004-08-30 |
2009-11-26 |
Janssen Pharmaceutica Nv |
Oxysteroid-dehydrogenase-inhibitoren
|
EA012263B1
(ru)
|
2004-08-30 |
2009-08-28 |
Янссен Фармацевтика Н.В. |
Производные n-2-адамантанил-2-феноксиацетамида в качестве ингибиторов 11-бета-гидроксистероид-дегидрогеназы
|
JP4882748B2
(ja)
*
|
2004-09-16 |
2012-02-22 |
アステラス製薬株式会社 |
トリアゾール誘導体またはその塩
|
US7759339B2
(en)
|
2005-03-31 |
2010-07-20 |
Takeda San Diego, Inc. |
Hydroxysteroid dehydrogenase inhibitors
|
KR100931411B1
(ko)
|
2005-04-05 |
2009-12-10 |
에프. 호프만-라 로슈 아게 |
1h-피라졸 4-카복실아미드, 이의 제조 방법, 및 이의 11베타-하이드록시스테로이드 탈수소효소로서의 용도
|
US7737155B2
(en)
|
2005-05-17 |
2010-06-15 |
Schering Corporation |
Nitrogen-containing heterocyclic compounds and methods of use thereof
|
US8952176B2
(en)
*
|
2005-06-07 |
2015-02-10 |
Shionogi & Co., Ltd. |
Heterocyclic compound having type I 11 β hydroxysteroid dehydrogenase inhibitory activity
|
US7572807B2
(en)
|
2005-06-09 |
2009-08-11 |
Bristol-Myers Squibb Company |
Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
|
US7579360B2
(en)
*
|
2005-06-09 |
2009-08-25 |
Bristol-Myers Squibb Company |
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
US7622492B2
(en)
|
2005-08-31 |
2009-11-24 |
Hoffmann-La Roche Inc. |
Pyrazolones as inhibitors of 11β-hydroxysteroid dehydrogenase
|
CN101374523B
(zh)
|
2005-09-14 |
2012-04-11 |
武田药品工业株式会社 |
用于治疗糖尿病的二肽基肽酶抑制剂
|
JP5122462B2
(ja)
|
2005-09-16 |
2013-01-16 |
武田薬品工業株式会社 |
ジペプチジルペプチダーゼ阻害剤
|
RU2302066C1
(ru)
*
|
2005-09-22 |
2007-06-27 |
Научный центр волоконной оптики при Институте общей физики им. А.М. Прохорова Российской академии наук |
Волоконный световод для оптического усиления излучения на длине волны в диапазоне 1000-1700 нм, способы его изготовления и волоконный лазер
|
JP4879988B2
(ja)
|
2005-09-29 |
2012-02-22 |
メルク・シャープ・エンド・ドーム・コーポレイション |
メラノコルチン−4受容体モジュレーターとしてのアシル化スピロピペリジン誘導体
|
AU2006316087B2
(en)
*
|
2005-11-21 |
2011-03-10 |
Shionogi & Co., Ltd. |
Heterocyclic compound having inhibitory activity on 11-beta-hydroxysteroid dehydrogenase type I
|
US7998959B2
(en)
|
2006-01-12 |
2011-08-16 |
Incyte Corporation |
Modulators of 11-β hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
|
CN101370796B
(zh)
|
2006-01-18 |
2012-10-10 |
霍夫曼-拉罗奇有限公司 |
作为11β-HSD1抑制剂的噻唑类
|
WO2007088895A1
(ja)
*
|
2006-01-31 |
2007-08-09 |
Mochida Pharmaceutical Co., Ltd. |
3-アリールアミノ-1,2,4-トリアゾール誘導体
|
US7834178B2
(en)
|
2006-03-01 |
2010-11-16 |
Bristol-Myers Squibb Company |
Triazine 11-beta hydroxysteroid dehydrogenase type 1 inhibitors
|
BRPI0708782A2
(pt)
|
2006-03-16 |
2011-06-14 |
Astellas Pharma Inc |
derivado de triazol ou um sal deste
|
WO2007112347A1
(en)
|
2006-03-28 |
2007-10-04 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
PE20110235A1
(es)
|
2006-05-04 |
2011-04-14 |
Boehringer Ingelheim Int |
Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
|
BRPI0715160A2
(pt)
|
2006-08-08 |
2013-06-11 |
Sanofi Aventis |
imidazolidina-2,4-dionas substituÍdas por arilamimoaril-alquil-, processo para preparÁ-las, medicamentos compeendendo estes compostos, e seu uso
|
AU2007287070C1
(en)
|
2006-08-24 |
2013-02-14 |
University Of Tennessee Research Foundation |
Substituted acylanilides and methods of use thereof
|
US8324383B2
(en)
|
2006-09-13 |
2012-12-04 |
Takeda Pharmaceutical Company Limited |
Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
|
CA2770486C
(en)
|
2006-09-22 |
2014-07-15 |
Merck Sharp & Dohme Corp. |
Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer
|
TW200838536A
(en)
|
2006-11-29 |
2008-10-01 |
Takeda Pharmaceutical |
Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
|
UY30820A1
(es)
*
|
2006-12-21 |
2008-07-03 |
Centocor Inc |
Uso de agonistas del receptor de glp-1 de accion prolongada para mejorar la sensibilidad a la insulina y los perfiles lipidicos
|
DE102007005045B4
(de)
|
2007-01-26 |
2008-12-18 |
Sanofi-Aventis |
Phenothiazin Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
US8093236B2
(en)
|
2007-03-13 |
2012-01-10 |
Takeda Pharmaceuticals Company Limited |
Weekly administration of dipeptidyl peptidase inhibitors
|
AU2008233662B2
(en)
|
2007-04-02 |
2012-08-23 |
Msd K.K. |
Indoledione derivative
|
DK2163543T3
(en)
|
2007-05-18 |
2015-04-27 |
Shionogi & Co |
Nitrogenholdigt heterocyklisk derivat med 11beta-hydroxysteroiddehydrogenase-type 1-inhibitorisk aktivitet
|
JP5223864B2
(ja)
|
2007-06-27 |
2013-06-26 |
大正製薬株式会社 |
11β−HSD1阻害活性を有する化合物
|
EP2025674A1
(de)
|
2007-08-15 |
2009-02-18 |
sanofi-aventis |
Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
US8119658B2
(en)
|
2007-10-01 |
2012-02-21 |
Bristol-Myers Squibb Company |
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
WO2009126861A2
(en)
*
|
2008-04-11 |
2009-10-15 |
Bristol-Myers Squibb Company |
Triazolopyridine compounds useful as dgat1 inhibitors
|
WO2009126624A1
(en)
*
|
2008-04-11 |
2009-10-15 |
Bristol-Myers Squibb Company |
Triazolo compounds useful as dgat1 inhibitors
|
CA2729408C
(en)
*
|
2008-07-03 |
2016-05-10 |
Astellas Pharma Inc. |
Triazole derivative or salt thereof
|
EP2310372B1
(en)
|
2008-07-09 |
2012-05-23 |
Sanofi |
Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
|
NZ592544A
(en)
|
2008-10-30 |
2013-01-25 |
Merck Sharp & Dohme |
Isonicotinamide orexin receptor antagonists
|
JO2870B1
(en)
|
2008-11-13 |
2015-03-15 |
ميرك شارب اند دوهم كورب |
Amino Tetra Hydro Pirans as Inhibitors of Peptide Dipeptide IV for the Treatment or Prevention of Diabetes
|
JP5514831B2
(ja)
|
2008-11-17 |
2014-06-04 |
メルク・シャープ・アンド・ドーム・コーポレーション |
糖尿病の治療のための置換二環式アミン
|
WO2010068601A1
(en)
|
2008-12-08 |
2010-06-17 |
Sanofi-Aventis |
A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
|
CN102395567A
(zh)
*
|
2009-02-12 |
2012-03-28 |
埃克塞利希斯股份有限公司 |
在治疗糖尿病和肥胖症中用作的tgr5激动剂的***和咪唑衍生物
|
ES2350077B1
(es)
|
2009-06-04 |
2011-11-04 |
Laboratorios Salvat, S.A. |
Compuestos inhibidores de 11beta-hidroxiesteroide deshidrogenasa de tipo 1.
|
WO2011011506A1
(en)
|
2009-07-23 |
2011-01-27 |
Schering Corporation |
Spirocyclic oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors
|
US20120220567A1
(en)
|
2009-07-23 |
2012-08-30 |
Shipps Jr Gerald W |
Benzo-fused oxazepine compounds as stearoyl-coenzyme a delta-9 desaturase inhibitors
|
EP2464228B1
(en)
|
2009-08-13 |
2017-12-06 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment
|
BR112012003973A2
(pt)
|
2009-08-26 |
2015-09-08 |
Sanofi Sa |
hidratos de fluoroglicosídeo heteroaromático cristalinos, produtos farmacêuticos compreendendo estes compostos e seu uso
|
WO2011028455A1
(en)
|
2009-09-02 |
2011-03-10 |
Merck Sharp & Dohme Corp. |
Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
WO2011071957A1
(en)
|
2009-12-07 |
2011-06-16 |
Sea Lane Biotechnologies, Llc |
Conjugates comprising an antibody surrogate scaffold with improved pharmacokinetic properties
|
TW201120027A
(en)
*
|
2009-12-11 |
2011-06-16 |
Exelixis Inc |
TGR5 agonists
|
US8853212B2
(en)
|
2010-02-22 |
2014-10-07 |
Merck Sharp & Dohme Corp |
Substituted aminotetrahydrothiopyrans and derivatives thereof as dipeptidyl peptidase-IV inhibitors for the treatment of diabetes
|
WO2011107494A1
(de)
|
2010-03-03 |
2011-09-09 |
Sanofi |
Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
EP2571876B1
(en)
|
2010-05-21 |
2016-09-07 |
Merck Sharp & Dohme Corp. |
Substituted seven-membered heterocyclic compounds as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes
|
WO2011157827A1
(de)
|
2010-06-18 |
2011-12-22 |
Sanofi |
Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
|
US8530413B2
(en)
|
2010-06-21 |
2013-09-10 |
Sanofi |
Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
|
TW201215387A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Aventis |
Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
|
TW201215388A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Sa |
(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
EP2605658B1
(en)
|
2010-08-18 |
2016-03-23 |
Merck Sharp & Dohme Corp. |
Spiroxazolidinone compounds
|
UA112418C2
(uk)
|
2010-09-07 |
2016-09-12 |
Астеллас Фарма Інк. |
Терапевтичний болезаспокійливий засіб
|
PE20131371A1
(es)
|
2010-09-22 |
2013-11-25 |
Arena Pharm Inc |
Moduladores del receptor gpr119 y el tratamiento de trastornos relacionados con este
|
WO2012120053A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
US8846666B2
(en)
|
2011-03-08 |
2014-09-30 |
Sanofi |
Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
|
EP2683705B1
(de)
|
2011-03-08 |
2015-04-22 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
EP2683698B1
(de)
|
2011-03-08 |
2017-10-04 |
Sanofi |
Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
US8710050B2
(en)
|
2011-03-08 |
2014-04-29 |
Sanofi |
Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
|
US8895547B2
(en)
|
2011-03-08 |
2014-11-25 |
Sanofi |
Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
|
US8809324B2
(en)
|
2011-03-08 |
2014-08-19 |
Sanofi |
Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
|
US8901114B2
(en)
|
2011-03-08 |
2014-12-02 |
Sanofi |
Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
|
WO2012120056A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
EP2693882B1
(en)
|
2011-04-08 |
2017-06-28 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment
|
ES2617215T3
(es)
*
|
2011-04-19 |
2017-06-15 |
Daiichi Sankyo Company, Limited |
Derivado de tetrahirotiazepina
|
CA2837517A1
(en)
|
2011-06-02 |
2012-12-06 |
Intervet International B.V. |
Imidazole derivatives
|
EP2720544B1
(en)
|
2011-06-16 |
2016-12-21 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds, and methods of treatment
|
WO2013037390A1
(en)
|
2011-09-12 |
2013-03-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
WO2013045413A1
(en)
|
2011-09-27 |
2013-04-04 |
Sanofi |
6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
WO2013048916A1
(en)
|
2011-09-30 |
2013-04-04 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment
|
AR088352A1
(es)
|
2011-10-19 |
2014-05-28 |
Merck Sharp & Dohme |
Antagonistas del receptor de 2-piridiloxi-4-nitrilo orexina
|
WO2013062838A1
(en)
|
2011-10-24 |
2013-05-02 |
Merck Sharp & Dohme Corp. |
Substituted piperidinyl compounds useful as gpr119 agonists
|
WO2013068328A1
(en)
|
2011-11-07 |
2013-05-16 |
Intervet International B.V. |
Bicyclo [2.2.2] octan-1-ylcarboxylic acid compounds as dgat-1 inhibitors
|
WO2013068439A1
(en)
|
2011-11-09 |
2013-05-16 |
Intervet International B.V. |
4-amino-5-oxo-7,8-dihydropyrimido[5, 4 -f] [1, 4] oxazepine compounds as dgat1 inhibitors
|
US9018224B2
(en)
|
2011-11-15 |
2015-04-28 |
Merck Sharp & Dohme Corp. |
Substituted cyclopropyl compounds useful as GPR119 agonists
|
EP2814485A4
(en)
|
2012-02-17 |
2015-08-26 |
Merck Sharp & Dohme |
DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
|
KR20140145624A
(ko)
|
2012-04-16 |
2014-12-23 |
카네크 파마 인코포레이티드 |
Ptp-1b 억제제에 대한 전구체로서의 융합된 방향족 포스포네이트 유도체
|
US10314807B2
(en)
|
2012-07-13 |
2019-06-11 |
Gtx, Inc. |
Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
|
KR102122941B1
(ko)
|
2012-07-13 |
2020-06-15 |
지티엑스, 인코포레이티드 |
선택적 안드로겐 수용체 조절자(sarms)를 이용한 안드로겐 수용체(ar) 양성 유방암의 치료 방법
|
US9622992B2
(en)
|
2012-07-13 |
2017-04-18 |
Gtx, Inc. |
Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
|
US9744149B2
(en)
|
2012-07-13 |
2017-08-29 |
Gtx, Inc. |
Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
|
US9969683B2
(en)
|
2012-07-13 |
2018-05-15 |
Gtx, Inc. |
Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS)
|
US10987334B2
(en)
|
2012-07-13 |
2021-04-27 |
University Of Tennessee Research Foundation |
Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs)
|
US10258596B2
(en)
|
2012-07-13 |
2019-04-16 |
Gtx, Inc. |
Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
|
EP2874622A4
(en)
|
2012-07-23 |
2015-12-30 |
Merck Sharp & Dohme |
TREATMENT OF DIABETES WITH DIPEPTIDYLPEPTIDASE IV INHIBITORS
|
JP2015525782A
(ja)
|
2012-08-02 |
2015-09-07 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
抗糖尿病性三環式化合物
|
WO2014099578A1
(en)
|
2012-12-17 |
2014-06-26 |
Merck Sharp & Dohme Corp. |
Novel glucokinase activator compounds, compositions containing such compounds, and methods of treatment
|
WO2015051496A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
WO2015089809A1
(en)
|
2013-12-19 |
2015-06-25 |
Merck Sharp & Dohme Corp. |
Antidiabetic substituted heteroaryl compounds
|
EP3097101B1
(en)
|
2014-01-24 |
2020-12-23 |
Merck Sharp & Dohme Corp. |
Isoquinoline derivatives as mgat2 inhibitors
|
JP6553094B2
(ja)
*
|
2014-06-12 |
2019-07-31 |
ユニヴェルシテ・ドゥ・リール・2・ドロワ・エ・サンテ |
イミダゾール−または1,2,4−トリアゾール−誘導体及びその使用
|
WO2016022742A1
(en)
|
2014-08-08 |
2016-02-11 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
WO2016022446A1
(en)
|
2014-08-08 |
2016-02-11 |
Merck Sharp & Dohme Corp. |
[5,6]-fused bicyclic antidiabetic compounds
|
EP3177282B1
(en)
|
2014-08-08 |
2021-10-06 |
Merck Sharp & Dohme Corp. |
Antidiabetic bicyclic compounds
|
KR101996739B1
(ko)
|
2014-10-24 |
2019-10-01 |
머크 샤프 앤드 돔 코포레이션 |
글루카곤 및 glp-1 수용체의 공-효능제
|
NZ730054A
(en)
|
2014-10-31 |
2023-11-24 |
Ngm Biopharmaceuticals Inc |
Compositions and methods of use for treating metabolic disorders
|
TW201625635A
(zh)
|
2014-11-21 |
2016-07-16 |
默沙東藥廠 |
作為可溶性鳥苷酸環化酶活化劑之***并吡基衍生物
|
KR20230151072A
(ko)
|
2015-01-06 |
2023-10-31 |
아레나 파마슈티칼스, 인크. |
S1p1 수용체와 관련된 상태의 치료 방법
|
WO2016191334A1
(en)
|
2015-05-27 |
2016-12-01 |
Merck Sharp & Dohme Corp. |
Imidazo-pyrazinyl derivatives useful as soluble guanylate cyclase activators
|
US10213429B2
(en)
|
2015-05-28 |
2019-02-26 |
Merck Sharp & Dohme Corp. |
Imidazo-pyrazinyl derivatives useful as soluble guanylate cyclase activators
|
CA3002551A1
(en)
|
2015-06-22 |
2016-12-29 |
Arena Pharmaceuticals, Inc. |
Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(com pound 1)for use in s1p1 receptor-associated disorders
|
US10800826B2
(en)
|
2015-10-05 |
2020-10-13 |
Merck Sharp & Dohme Corp. |
Antibody peptide conjugates that have agonist activity at both the glucagon and glucagon-like peptide 1 receptors
|
WO2017107052A1
(en)
|
2015-12-22 |
2017-06-29 |
Merck Sharp & Dohme Corp. |
Soluble guanylate cyclase stimulators
|
EP3235813A1
(en)
|
2016-04-19 |
2017-10-25 |
Cidqo 2012, S.L. |
Aza-tetra-cyclo derivatives
|
WO2017197555A1
(en)
|
2016-05-16 |
2017-11-23 |
Merck Sharp & Dohme Corp. |
Fused pyrazine derivatives useful as soluble guanylate cyclase stimulators
|
WO2017201683A1
(en)
|
2016-05-25 |
2017-11-30 |
Merck Sharp & Dohme Corp. |
Substituted tetrahydroisoquinoline compounds useful as gpr120 agonists
|
WO2018034917A1
(en)
|
2016-08-15 |
2018-02-22 |
Merck Sharp & Dohme Corp. |
Compounds useful for altering the levels of bile acids for the treatment of diabetes and cardiometabolic disease
|
WO2018034918A1
(en)
|
2016-08-15 |
2018-02-22 |
Merck Sharp & Dohme Corp. |
Compounds useful for altering the levels of bile acids for the treatment of diabetes and cardiometabolic disease
|
US11008313B2
(en)
|
2016-09-20 |
2021-05-18 |
Merck Sharp & Dohme Corp. |
Substituted 1-methyl-1,2,3,4-tetrahydroisoquinoline molecules as PCSK9 allosteric binders
|
RU2019117958A
(ru)
|
2016-11-18 |
2020-12-18 |
Мерк Шарп И Доум Корп. |
Производные индола, полезные в качестве ингибиторов диацилглицерид-о-ацилтрансферазы 2
|
WO2018107415A1
(en)
|
2016-12-15 |
2018-06-21 |
Merck Sharp & Dohme Corp. |
Hydroxy isoxazole compounds useful as gpr120 agonists
|
MA47504A
(fr)
|
2017-02-16 |
2019-12-25 |
Arena Pharm Inc |
Composés et méthodes de traitement de l'angiocholite biliaire primitive
|
JOP20190150A1
(ar)
|
2018-06-21 |
2019-12-21 |
Merck Sharp & Dohme |
مركبات مناهضة لـ pcsk9
|
WO2020167706A1
(en)
|
2019-02-13 |
2020-08-20 |
Merck Sharp & Dohme Corp. |
5-alkyl pyrrolidine orexin receptor agonists
|
US20220177465A1
(en)
|
2019-04-04 |
2022-06-09 |
Merck Sharp & Dohme Corp. |
Inhibitors of histone deacetylase-3 useful for the treatment of cancer, inflammation, neurodegeneration diseases and diabetes
|
WO2021026047A1
(en)
|
2019-08-08 |
2021-02-11 |
Merck Sharp & Dohme Corp. |
Heteroaryl pyrrolidine and piperidine orexin receptor agonists
|
US11484565B2
(en)
|
2019-08-30 |
2022-11-01 |
Merck Sharp & Dohme Llc |
PCSK9 antagonist compounds
|
EP3842061A1
(en)
|
2019-12-23 |
2021-06-30 |
Merck Sharp & Dohme Corp. |
Stapled triazole co-agonists of the glucagon and glp-1 receptors
|
EP3842060A1
(en)
|
2019-12-23 |
2021-06-30 |
Merck Sharp & Dohme Corp. |
Stapled lactam co-agonists of the glucagon and glp-1 receptors
|
EP3842449A1
(en)
|
2019-12-23 |
2021-06-30 |
Merck Sharp & Dohme Corp. |
Stapled olefin co-agonists of the glucagon and glp-1 receptors
|
US11787810B2
(en)
|
2020-05-18 |
2023-10-17 |
Merck Sharp & Dohme Llc |
Diacylglyceride O-acyltransferase 2 inhibitors
|
AU2021329805B2
(en)
|
2020-08-18 |
2024-02-29 |
Merck Sharp & Dohme Llc |
Bicycloheptane pyrrolidine orexin receptor agonists
|
KR102445638B1
(ko)
|
2020-09-03 |
2022-09-20 |
충남대학교산학협력단 |
11 알파 하이드록시프로게스테론을 포함하는 당뇨병 예방 또는 치료용 조성물
|
KR20230084258A
(ko)
|
2020-10-08 |
2023-06-12 |
머크 샤프 앤드 돔 엘엘씨 |
신규 디아실글리세리드 o-아실트랜스퍼라제 2 억제제로서의 벤즈이미다졸론 유도체의 제조
|
WO2023023245A1
(en)
|
2021-08-19 |
2023-02-23 |
Merck Sharp & Dohme Llc |
Compounds for treating conditions related to pcsk9 activity
|
CN116003279A
(zh)
*
|
2022-06-13 |
2023-04-25 |
苏州大学 |
一种绿色的n-甲基酰胺化合物的制备方法
|
US20230406885A1
(en)
|
2022-06-15 |
2023-12-21 |
Merck Sharp & Dohme Llc |
Cyclic peptides for trapping interleukin-1 beta
|