ATE402699T1 - Verwendung von substituierten pyrazolen zur behandlung von allergien - Google Patents
Verwendung von substituierten pyrazolen zur behandlung von allergienInfo
- Publication number
- ATE402699T1 ATE402699T1 AT01968487T AT01968487T ATE402699T1 AT E402699 T1 ATE402699 T1 AT E402699T1 AT 01968487 T AT01968487 T AT 01968487T AT 01968487 T AT01968487 T AT 01968487T AT E402699 T1 ATE402699 T1 AT E402699T1
- Authority
- AT
- Austria
- Prior art keywords
- substituted pyrazoles
- treat allergies
- allergies
- treat
- pyrazoles
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23040700P | 2000-09-06 | 2000-09-06 | |
US09/927,188 US6635633B2 (en) | 2000-08-14 | 2001-08-10 | Substituted pyrazoles |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE402699T1 true ATE402699T1 (de) | 2008-08-15 |
Family
ID=26924202
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01968487T ATE402699T1 (de) | 2000-09-06 | 2001-09-05 | Verwendung von substituierten pyrazolen zur behandlung von allergien |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP1315492B1 (de) |
JP (1) | JP4129391B2 (de) |
CN (1) | CN1321641C (de) |
AT (1) | ATE402699T1 (de) |
AU (2) | AU8873101A (de) |
CA (1) | CA2421510A1 (de) |
DE (1) | DE60135130D1 (de) |
DK (1) | DK1315492T3 (de) |
ES (1) | ES2309088T3 (de) |
HK (1) | HK1052881B (de) |
MX (1) | MXPA03001962A (de) |
NZ (1) | NZ524682A (de) |
PT (1) | PT1315492E (de) |
WO (1) | WO2002020013A2 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2421493A1 (en) * | 2000-09-06 | 2002-03-14 | Ortho-Mcneil Pharmaceutical, Inc. | A method for treating allergies using substituted pyrazoles |
ES2201899B1 (es) | 2002-04-01 | 2005-06-01 | Almirall Prodesfarma, S.A. | Derivados de la azaindolilpiperidina como agentes antihistaminicos y antialergicos. |
ES2201907B1 (es) | 2002-05-29 | 2005-06-01 | Almirall Prodesfarma, S.A. | Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos. |
KR20070034049A (ko) | 2004-06-09 | 2007-03-27 | 글락소 그룹 리미티드 | 피롤로피리딘 유도체 |
DK3141252T3 (en) | 2009-06-17 | 2018-11-19 | Vertex Pharma | INHIBITORS OF INFLUENZA VIRUS REPLICATION |
CA2822057A1 (en) | 2010-12-16 | 2012-06-21 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
CA2838784A1 (en) | 2011-08-12 | 2013-02-21 | F. Hoffmann-La Roche Ag | Pyrazolo[3,4-c]pyridine compounds and methods of use |
MX2016006199A (es) | 2013-11-13 | 2016-08-08 | Vertex Pharma | Inhibidores de replicacion del virus de influenza. |
EP3421468B1 (de) | 2013-11-13 | 2020-11-04 | Vertex Pharmaceuticals Incorporated | Verfahren zur herstellung von inhibitoren der influenzavirenreplikation |
MA42422A (fr) | 2015-05-13 | 2018-05-23 | Vertex Pharma | Inhibiteurs de la réplication des virus de la grippe |
JP6704416B2 (ja) | 2015-05-13 | 2020-06-03 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | インフルエンザウイルスの複製の阻害剤を調製する方法 |
AU2019353144B2 (en) | 2018-10-05 | 2023-11-16 | Annapurna Bio, Inc. | Compounds and compositions for treating conditions associated with APJ receptor activity |
CN111518019B (zh) * | 2019-02-01 | 2023-10-24 | 江苏豪森药业集团有限公司 | 一种棕榈酸帕里哌酮中间体的制备方法 |
CN112142744A (zh) * | 2019-06-28 | 2020-12-29 | 上海瑛派药业有限公司 | 取代的稠合杂芳双环化合物作为激酶抑制剂及其应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE789948A (fr) * | 1971-10-13 | 1973-04-11 | Sandoz Sa | Nouveaux derives du pyrazole, leur preparation et leur application comme medicaments |
JPH0615542B2 (ja) * | 1986-07-22 | 1994-03-02 | 吉富製薬株式会社 | ピラゾロピリジン化合物 |
JP3907220B2 (ja) * | 1994-06-30 | 2007-04-18 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 複素環含有化合物 |
JP3964478B2 (ja) * | 1995-06-30 | 2007-08-22 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ヘテロ環含有カルボン酸誘導体及びそれを含有する医薬 |
WO1998056785A1 (fr) * | 1997-06-12 | 1998-12-17 | Sumitomo Pharmaceuticals Co., Ltd. | Derives de pyrazole |
-
2001
- 2001-09-05 JP JP2002524497A patent/JP4129391B2/ja not_active Expired - Fee Related
- 2001-09-05 CN CNB018185045A patent/CN1321641C/zh not_active Expired - Lifetime
- 2001-09-05 PT PT01968487T patent/PT1315492E/pt unknown
- 2001-09-05 AU AU8873101A patent/AU8873101A/xx active Pending
- 2001-09-05 AU AU2001288731A patent/AU2001288731B8/en not_active Expired
- 2001-09-05 NZ NZ524682A patent/NZ524682A/en unknown
- 2001-09-05 DK DK01968487T patent/DK1315492T3/da active
- 2001-09-05 AT AT01968487T patent/ATE402699T1/de not_active IP Right Cessation
- 2001-09-05 ES ES01968487T patent/ES2309088T3/es not_active Expired - Lifetime
- 2001-09-05 EP EP01968487A patent/EP1315492B1/de not_active Expired - Lifetime
- 2001-09-05 CA CA002421510A patent/CA2421510A1/en not_active Abandoned
- 2001-09-05 MX MXPA03001962A patent/MXPA03001962A/es active IP Right Grant
- 2001-09-05 DE DE60135130T patent/DE60135130D1/de not_active Expired - Lifetime
- 2001-09-05 WO PCT/US2001/027480 patent/WO2002020013A2/en active IP Right Grant
-
2003
- 2003-07-17 HK HK03105185.1A patent/HK1052881B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU2001288731B2 (en) | 2005-12-15 |
DE60135130D1 (de) | 2008-09-11 |
MXPA03001962A (es) | 2004-03-26 |
AU8873101A (en) | 2002-03-22 |
CN1321641C (zh) | 2007-06-20 |
JP4129391B2 (ja) | 2008-08-06 |
WO2002020013A2 (en) | 2002-03-14 |
ES2309088T3 (es) | 2008-12-16 |
CN1505509A (zh) | 2004-06-16 |
AU2001288731B8 (en) | 2006-04-13 |
WO2002020013A3 (en) | 2002-06-20 |
HK1052881B (zh) | 2009-01-30 |
NZ524682A (en) | 2004-11-26 |
HK1052881A1 (en) | 2003-10-03 |
DK1315492T3 (da) | 2008-10-13 |
EP1315492A2 (de) | 2003-06-04 |
PT1315492E (pt) | 2008-10-01 |
CA2421510A1 (en) | 2002-03-14 |
JP2004508330A (ja) | 2004-03-18 |
EP1315492B1 (de) | 2008-07-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60136546D1 (de) | Methode zum bekämpfen der allergien durch verwendung von substituierten pyrazolen | |
ATE402699T1 (de) | Verwendung von substituierten pyrazolen zur behandlung von allergien | |
DE60219793D1 (de) | Methode zur behandlung von zytokinvermittelten erkrankungen | |
DE602004017736D1 (de) | Verwendung von rapamycin und dessen derivaten zur behandlung von knochenverlust | |
DE60325770D1 (de) | Verwendung von rimexolon zur behandlung von augentrockenheit | |
ATE254461T1 (de) | Behandlung von augenschmerzen | |
ATE552842T1 (de) | Verwendung von plasminogen zur wundheilung | |
DE60130661D1 (de) | Verwendung der 13-cis retinsäure zur behandlung von emphysemen | |
NO20025405D0 (no) | Modulatorer for TNF-alfa-signalisering | |
DE602004022035D1 (de) | Verwendung von pthalide derivativen zur behandlung | |
ATE353667T1 (de) | Verwendung von proteasom-inhibitoren zur behandlung des trockenen auges | |
DE60328603D1 (de) | Prodrugs von imidazol-derivaten, zur verwendung als protonenpumpen-hemmer zur behandlung von z.b. peptischen magengeschwüren | |
ATE359283T1 (de) | Substituierte pyrazinonverbindungen zur behandlung von entzündungen | |
ATE273276T1 (de) | Cyclobutendion-derivate zur behandlung von artherosclerose | |
EA200701584A1 (ru) | Органические соединения, применяемые для лечения болезни альцгеймера, их применение и способ получения | |
DE60131968D1 (de) | PYRANOÄ2,3-cÜIMIDAZOÄ1,2-aÜPYRIDIN-DERIVATE ZUR BEHANDLUNG VON GASTROINTESTINALEN ERKRANKUNGEN | |
ATE333869T1 (de) | Verwendung von mglur5 antagonisten zur behandlung von pruritischen zuständen | |
ATE267608T1 (de) | Verwendung von fsh zur behandlung von infertilität | |
DE60220825D1 (de) | Verwendung von norepinephrinwiederaufnahmehemmern zur behandlung von ticks | |
DE502004011486D1 (de) | Antioxidationsmittel für organisches material und verfahren zur behandlung desselben | |
DE60122171D1 (de) | Verwendung von substituierten pyrazolen zur herstellung eines medikaments zur behandlung von allergien | |
ATE423780T1 (de) | Makrozyclen zur behandlung von krebserkrankungen | |
ATE359088T1 (de) | Verwendung von interleukin-18 zur behandlung von uv-assoziierten hautkrankheiten | |
DE60203882D1 (de) | Verwendung von 2-amino-1-(4-hydroxy-3-methanesulphonamidophenyl)ethanol zur behandlung von harninkontinenz |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1315492 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |