DE60130661D1 - Verwendung der 13-cis retinsäure zur behandlung von emphysemen - Google Patents
Verwendung der 13-cis retinsäure zur behandlung von emphysemenInfo
- Publication number
- DE60130661D1 DE60130661D1 DE60130661T DE60130661T DE60130661D1 DE 60130661 D1 DE60130661 D1 DE 60130661D1 DE 60130661 T DE60130661 T DE 60130661T DE 60130661 T DE60130661 T DE 60130661T DE 60130661 D1 DE60130661 D1 DE 60130661D1
- Authority
- DE
- Germany
- Prior art keywords
- emphysemes
- treatment
- retinic acid
- cis retinic
- cis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000002253 acid Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/631,151 US6339107B1 (en) | 2000-08-02 | 2000-08-02 | Methods for treatment of Emphysema using 13-cis retinoic acid |
US631151 | 2000-08-02 | ||
PCT/EP2001/008484 WO2002009679A2 (en) | 2000-08-02 | 2001-07-23 | Use of 13-cis retinoic acid for the treatment of emphysema |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60130661D1 true DE60130661D1 (de) | 2007-11-08 |
DE60130661T2 DE60130661T2 (de) | 2008-07-03 |
Family
ID=24529991
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60130661T Expired - Fee Related DE60130661T2 (de) | 2000-08-02 | 2001-07-23 | Verwendung der 13-cis retinsäure zur behandlung von emphysemen |
Country Status (7)
Country | Link |
---|---|
US (2) | US6339107B1 (de) |
EP (1) | EP1307187B1 (de) |
JP (1) | JP2004505036A (de) |
AU (1) | AU2001289726A1 (de) |
DE (1) | DE60130661T2 (de) |
ES (1) | ES2292620T3 (de) |
WO (1) | WO2002009679A2 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6720001B2 (en) * | 1999-10-18 | 2004-04-13 | Lipocine, Inc. | Emulsion compositions for polyfunctional active ingredients |
US6339107B1 (en) * | 2000-08-02 | 2002-01-15 | Syntex (U.S.A.) Llc | Methods for treatment of Emphysema using 13-cis retinoic acid |
JP2005501810A (ja) * | 2001-03-22 | 2005-01-20 | バテル メモリアル インスティチュート | ポリマーおよび懸濁粒子を含有する電気流体力学的噴霧用の液体形成物 |
JP2005507934A (ja) * | 2001-10-30 | 2005-03-24 | ネクター セラピューティックス エイエル,コーポレイション | レチノイン酸の水溶性ポリマー結合体 |
US20030185762A1 (en) * | 2002-03-22 | 2003-10-02 | Cowan Siu Man L. | Highly aqueous liquid carrier formulations |
US20040122110A1 (en) * | 2002-09-06 | 2004-06-24 | Maccabee Mendy S. | Effect of vitamin A gel on paranasal sinus mucosal regeneration |
WO2006025395A1 (ja) * | 2004-08-31 | 2006-03-09 | Yasuhiko Shimizu | キャリアフリーの細胞増殖因子を用いた慢性閉塞性肺疾患に対する医薬および処置システム |
WO2006079209A1 (en) * | 2005-01-26 | 2006-08-03 | The University Of British Columbia | Pulmonary compositions comprising a vitamin a compound and a surfactant and uses thereof |
WO2007104030A1 (en) * | 2006-03-08 | 2007-09-13 | Kinemed, Inc. | Retinoids and related compounds for the treatment of neuroinflammatory conditions, diseases and disorders |
US20070254858A1 (en) * | 2006-04-27 | 2007-11-01 | Cronk Peter J | Contraceptive and Acne Medication Combination and Treatment of Acne and Other Diseases with Reduced Side Effects |
US20070254025A1 (en) * | 2006-04-27 | 2007-11-01 | Cronk Peter J | Oral contraceptive and acne medication combination and treatment of acne with reduced side effects |
EP2432553A2 (de) * | 2009-05-20 | 2012-03-28 | Ranbaxy Laboratories Limited | Flüssige dosierformen von isotretinoin |
US10022348B2 (en) | 2009-05-20 | 2018-07-17 | Sun Pharmaceutical Industries Limited | Topical solution of isotretinoin |
CN102458362A (zh) | 2009-05-20 | 2012-05-16 | 兰贝克赛实验室有限公司 | 外用类维生素a溶液 |
BR112015015421A2 (pt) * | 2012-12-27 | 2017-07-11 | Microdose Therapeutx Inc | métodos e composições para a administração de oxibutinina |
EP3348279B1 (de) * | 2015-09-10 | 2021-08-04 | National University Corporation Okayama University | Medizinische zusammensetzung zur prävention oder behandlung von entzündlichen atemwegserkrankungen |
CN113372368B (zh) * | 2020-03-09 | 2022-04-12 | 苏州爱科百发生物医药技术有限公司 | 一种弹性蛋白酶抑制剂前药及其用途 |
WO2023168608A1 (en) * | 2022-03-08 | 2023-09-14 | Mastery Biotech Co., Ltd. | Pharmaceutical composition including retinoic acid and carbohydrate and use thereof |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB334585A (en) * | 1929-06-06 | 1930-09-08 | British Glues And Chemicals Lt | Improvements in or relating to the separation of solids from liquids |
ZA791659B (en) | 1978-04-17 | 1980-04-30 | Ici Ltd | Process and apparatus for spraying liquid |
GB8504253D0 (en) | 1985-02-19 | 1985-03-20 | Ici Plc | Electrostatic spraying apparatus |
IL90069A (en) | 1988-04-26 | 1994-04-12 | Us Health | The use of 31 cysts of retinoic acid in the preparation of a drug for the treatment of congenital conjunctivitis |
DE3815221C2 (de) | 1988-05-04 | 1995-06-29 | Gradinger F Hermes Pharma | Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen |
GB9116909D0 (en) * | 1991-08-06 | 1991-09-18 | Salford Ultrafine Chem & Res | Morphine derivatives |
TW272187B (de) | 1992-05-20 | 1996-03-11 | Hoffmann La Roche | |
GB9225098D0 (en) | 1992-12-01 | 1993-01-20 | Coffee Ronald A | Charged droplet spray mixer |
GB9226717D0 (en) | 1992-12-22 | 1993-02-17 | Coffee Ronald A | Induction-operated electro-hydrodynamic spray device with means of modifying droplet trajectories |
GB9406255D0 (en) | 1994-03-29 | 1994-05-18 | Electrosols Ltd | Dispensing device |
GB9406171D0 (en) | 1994-03-29 | 1994-05-18 | Electrosols Ltd | Dispensing device |
GB9410658D0 (en) | 1994-05-27 | 1994-07-13 | Electrosols Ltd | Dispensing device |
ES2140069T3 (es) | 1995-03-14 | 2000-02-16 | Siemens Ag | Dispositivo atomizador ultrasonico con unidad dosificadora de precision desmontable. |
JP3142577B2 (ja) | 1995-03-14 | 2001-03-07 | シーメンス アクチエンゲゼルシヤフト | 着脱自在な精密計量供給ユニット |
WO1997039745A1 (en) | 1996-04-19 | 1997-10-30 | Sloan-Kettering Institute For Cancer Research | Use of inhaled retinoids in the prevention of cancer |
US6515022B2 (en) * | 1996-04-19 | 2003-02-04 | Sloan-Kettering Institute For Cancer Research | Use of inhaled retinoids in the treatment of lung diseases |
US5998486A (en) | 1997-07-08 | 1999-12-07 | Georgetown University School Of Medicine | Treatment of emphysema with retinoic acid or other retinoids by inducing formation of gas-exchange units (alveoli) |
US5954047A (en) | 1997-10-17 | 1999-09-21 | Systemic Pulmonary Development, Ltd. | Methods and apparatus for delivering aerosolized medication |
BR9908771A (pt) | 1998-03-16 | 2000-12-12 | Inhale Therapeutic Syst | Processos para a liberação de um agente ativo e de insulina para os pulmões de um paciente humano, dispositivo para aumentar a biodisponibilidade de um agente ativo, e, dispositivos para a liberação de um agente ativo e de insulina para os pulmões de um paciente humano |
US6339107B1 (en) * | 2000-08-02 | 2002-01-15 | Syntex (U.S.A.) Llc | Methods for treatment of Emphysema using 13-cis retinoic acid |
-
2000
- 2000-08-02 US US09/631,151 patent/US6339107B1/en not_active Expired - Fee Related
-
2001
- 2001-07-23 WO PCT/EP2001/008484 patent/WO2002009679A2/en active IP Right Grant
- 2001-07-23 EP EP01969477A patent/EP1307187B1/de not_active Expired - Lifetime
- 2001-07-23 JP JP2002515232A patent/JP2004505036A/ja active Pending
- 2001-07-23 AU AU2001289726A patent/AU2001289726A1/en not_active Abandoned
- 2001-07-23 ES ES01969477T patent/ES2292620T3/es not_active Expired - Lifetime
- 2001-07-23 DE DE60130661T patent/DE60130661T2/de not_active Expired - Fee Related
- 2001-09-26 US US09/966,202 patent/US6794416B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE60130661T2 (de) | 2008-07-03 |
US6794416B2 (en) | 2004-09-21 |
US20020049252A1 (en) | 2002-04-25 |
WO2002009679A2 (en) | 2002-02-07 |
WO2002009679A3 (en) | 2002-04-18 |
EP1307187A2 (de) | 2003-05-07 |
ES2292620T3 (es) | 2008-03-16 |
EP1307187B1 (de) | 2007-09-26 |
US6339107B1 (en) | 2002-01-15 |
AU2001289726A1 (en) | 2002-02-13 |
JP2004505036A (ja) | 2004-02-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |