ATE382619T1 - 4-hydroxy-4-methylpiperidin-1-carbonsäure-(4- methoxy-7-morpholin-4-ylbenzothiazol-2-yl)-amid - Google Patents

4-hydroxy-4-methylpiperidin-1-carbonsäure-(4- methoxy-7-morpholin-4-ylbenzothiazol-2-yl)-amid

Info

Publication number
ATE382619T1
ATE382619T1 AT05741185T AT05741185T ATE382619T1 AT E382619 T1 ATE382619 T1 AT E382619T1 AT 05741185 T AT05741185 T AT 05741185T AT 05741185 T AT05741185 T AT 05741185T AT E382619 T1 ATE382619 T1 AT E382619T1
Authority
AT
Austria
Prior art keywords
ylbenzothiazole
methylpiperidine
morpholine
methoxy
amide
Prior art date
Application number
AT05741185T
Other languages
English (en)
Inventor
Alexander Flohr
Jean-Luc Moreau
Sonia Poli
Claus Riemer
Lucinda Steward
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34967309&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE382619(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE382619T1 publication Critical patent/ATE382619T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT05741185T 2004-05-24 2005-05-17 4-hydroxy-4-methylpiperidin-1-carbonsäure-(4- methoxy-7-morpholin-4-ylbenzothiazol-2-yl)-amid ATE382619T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04102262 2004-05-24

Publications (1)

Publication Number Publication Date
ATE382619T1 true ATE382619T1 (de) 2008-01-15

Family

ID=34967309

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05741185T ATE382619T1 (de) 2004-05-24 2005-05-17 4-hydroxy-4-methylpiperidin-1-carbonsäure-(4- methoxy-7-morpholin-4-ylbenzothiazol-2-yl)-amid

Country Status (39)

Country Link
US (1) US7368446B2 (de)
EP (1) EP1753760B1 (de)
JP (1) JP4668265B2 (de)
CN (1) CN1956983B (de)
AR (1) AR048973A1 (de)
AT (1) ATE382619T1 (de)
AU (1) AU2005247567B2 (de)
BR (1) BRPI0511543B1 (de)
CA (1) CA2567703C (de)
CR (1) CR8703A (de)
CY (1) CY1108104T1 (de)
DE (1) DE602005004142T2 (de)
DK (1) DK1753760T3 (de)
DO (1) DOP2005000091A (de)
EA (1) EA011279B1 (de)
EC (1) ECSP067018A (de)
ES (1) ES2297710T3 (de)
GT (1) GT200500124A (de)
HK (1) HK1105199A1 (de)
HN (1) HN2005000238A (de)
HR (1) HRP20080027T3 (de)
IL (1) IL179364A (de)
MA (1) MA28601B1 (de)
MX (1) MXPA06013417A (de)
MY (1) MY140011A (de)
NO (1) NO336939B1 (de)
NZ (1) NZ550763A (de)
PA (1) PA8633901A1 (de)
PE (1) PE20060274A1 (de)
PL (1) PL1753760T3 (de)
PT (1) PT1753760E (de)
RS (1) RS50574B (de)
SI (1) SI1753760T1 (de)
SV (1) SV2006002125A (de)
TN (1) TNSN06371A1 (de)
TW (1) TWI358297B (de)
UA (1) UA87142C2 (de)
WO (1) WO2005116026A1 (de)
ZA (1) ZA200609136B (de)

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SE521512C2 (sv) * 2001-06-25 2003-11-11 Niconovum Ab Anordning för administrering av en substans till främre delen av en individs munhåla
EP1578422B1 (de) 2002-12-20 2007-04-11 NicoNovum AB Chemisch und physikalisch stabiles teilchenförmiges material enthaltend nikotin und microcrystalline cellulose
US9402809B2 (en) 2006-03-16 2016-08-02 Niconovum Usa, Inc. Snuff composition
NZ583191A (en) * 2007-07-23 2012-06-29 Biotie Therapies Inc 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide for the treatment of post-traumatic stress disorder
BRPI1006128A2 (pt) 2009-01-12 2016-11-01 Cagen Inc derivados de sulfonamida
US8168785B2 (en) 2009-06-17 2012-05-01 Biotie Therapies, Inc. Benzothiazole derivatives
WO2011101861A1 (en) 2010-01-29 2011-08-25 Msn Laboratories Limited Process for preparation of dpp-iv inhibitors
US9145407B2 (en) 2010-07-09 2015-09-29 Pfizer Limited Sulfonamide compounds
WO2012060844A1 (en) * 2010-11-05 2012-05-10 Biotie Therapies, Inc A2a antagonists as cognition and motor function enhancers
JP6042968B2 (ja) * 2012-04-20 2016-12-14 ユセベ ファルマ ソシエテ アノニム パーキンソン病の処置方法
CA2988918A1 (en) 2015-06-19 2016-12-22 Biotie Therapies, Inc. Controlled-release tozadenant formulations
WO2018059531A1 (zh) * 2016-09-30 2018-04-05 苏州晶云药物科技有限公司 一种腺苷a2a受体拮抗剂药物的晶型及其制备方法和用途
ES2964026T3 (es) * 2017-08-21 2024-04-03 Merck Patent Gmbh Derivados de quinoxalina como antagonistas de receptores de adenosina
JP7287952B2 (ja) * 2017-08-21 2023-06-06 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング アデノシン受容体アンタゴニストとしてのベンズイミダゾール誘導体
WO2019141096A1 (zh) * 2018-01-19 2019-07-25 四川科伦博泰生物医药股份有限公司 取代脲类化合物及其制备方法和用途
US20220088024A1 (en) 2018-12-20 2022-03-24 Biotie Therapies, Inc. Methods for treating cancer using tozadenant
DE102019110904B4 (de) 2019-04-26 2022-01-20 Helmholtz-Zentrum Dresden - Rossendorf E. V. N-(4-methoxy-7-morpholinobenzo[d]thiazol-2-yl)-acetamid-Derivate und deren Verwendung

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UA71587C2 (uk) 1998-11-10 2004-12-15 Шерінг Акцієнгезелльшафт Аміди антранілової кислоти та їхнє застосування як лікарських засобів
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Also Published As

Publication number Publication date
TW200612937A (en) 2006-05-01
EA011279B1 (ru) 2009-02-27
CA2567703A1 (en) 2005-12-08
WO2005116026A1 (en) 2005-12-08
AR048973A1 (es) 2006-06-14
DE602005004142D1 (de) 2008-02-14
MY140011A (en) 2009-11-30
RS50574B (sr) 2010-05-07
HN2005000238A (es) 2008-07-14
DE602005004142T2 (de) 2009-01-02
AU2005247567B2 (en) 2010-09-02
SV2006002125A (es) 2006-02-15
MXPA06013417A (es) 2007-01-23
CN1956983B (zh) 2010-05-26
ES2297710T3 (es) 2008-05-01
HK1105199A1 (en) 2008-02-06
NZ550763A (en) 2010-07-30
PL1753760T3 (pl) 2008-06-30
EP1753760B1 (de) 2008-01-02
DOP2005000091A (es) 2005-06-29
NO336939B1 (no) 2015-11-30
MA28601B1 (fr) 2007-05-02
PA8633901A1 (es) 2006-05-16
JP4668265B2 (ja) 2011-04-13
BRPI0511543A (pt) 2008-01-02
TNSN06371A1 (fr) 2008-02-22
IL179364A (en) 2013-01-31
BRPI0511543B1 (pt) 2022-05-10
TWI358297B (en) 2012-02-21
IL179364A0 (en) 2007-03-08
CY1108104T1 (el) 2014-02-12
JP2008500295A (ja) 2008-01-10
PT1753760E (pt) 2008-02-12
EP1753760A1 (de) 2007-02-21
CA2567703C (en) 2013-03-05
US20050261289A1 (en) 2005-11-24
AU2005247567A1 (en) 2005-12-08
UA87142C2 (en) 2009-06-25
ZA200609136B (en) 2008-07-30
EA200602048A1 (ru) 2007-06-29
ECSP067018A (es) 2006-12-29
CN1956983A (zh) 2007-05-02
US7368446B2 (en) 2008-05-06
SI1753760T1 (sl) 2008-04-30
NO20065732L (no) 2006-12-22
HRP20080027T3 (en) 2008-05-31
PE20060274A1 (es) 2006-04-14
GT200500124A (es) 2005-12-26
CR8703A (es) 2007-10-04
DK1753760T3 (da) 2008-04-14

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