US5951974A
(en)
*
|
1993-11-10 |
1999-09-14 |
Enzon, Inc. |
Interferon polymer conjugates
|
JP2000507917A
(ja)
|
1995-11-02 |
2000-06-27 |
シェーリング コーポレイション |
持続的低用量サイトカイン注入治療
|
US5908621A
(en)
|
1995-11-02 |
1999-06-01 |
Schering Corporation |
Polyethylene glycol modified interferon therapy
|
TW517067B
(en)
*
|
1996-05-31 |
2003-01-11 |
Hoffmann La Roche |
Interferon conjugates
|
US6214966B1
(en)
*
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
US20030190307A1
(en)
*
|
1996-12-24 |
2003-10-09 |
Biogen, Inc. |
Stable liquid interferon formulations
|
US20050158273A1
(en)
*
|
1997-09-25 |
2005-07-21 |
Harris J. M. |
Soluble, degradable polyethylene glycol) derivatives for controllable release of bound molecules into solution
|
US5981709A
(en)
*
|
1997-12-19 |
1999-11-09 |
Enzon, Inc. |
α-interferon-polymer-conjugates having enhanced biological activity and methods of preparing the same
|
US5985263A
(en)
*
|
1997-12-19 |
1999-11-16 |
Enzon, Inc. |
Substantially pure histidine-linked protein polymer conjugates
|
FR2774687B1
(fr)
*
|
1998-02-06 |
2002-03-22 |
Inst Nat Sante Rech Med |
Lipopeptides contenant un fragment de l'interferon gamma, et leur utilisation dans des compositions pharmaceutiques
|
HU228877B1
(en)
*
|
1998-03-26 |
2013-06-28 |
Merck Sharp & Dohme |
Formulations for stabilization of peg-interferon alpha conjugates and method for preparation such formulations
|
US6180096B1
(en)
|
1998-03-26 |
2001-01-30 |
Schering Corporation |
Formulations for protection of peg-interferon alpha conjugates
|
PL200586B1
(pl)
*
|
1998-10-16 |
2009-01-30 |
Biogen Idec Inc |
Polipeptydy zawierające mutanty interferonu-beta-1a, kodujące je cząsteczki kwasów nukleinowych, komórki gospodarza transformowane tymi cząsteczkami, sposób wytwarzania polipeptydów, zawierające je kompozycje farmaceutyczne i zastosowania polipeptydów
|
EP1656952B1
(de)
|
1998-10-16 |
2013-12-18 |
Biogen Idec MA Inc. |
Polyalkylenglykol-Konjugate von Interferon beta-1A und ihre Verwendungen
|
US7169889B1
(en)
*
|
1999-06-19 |
2007-01-30 |
Biocon Limited |
Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin
|
IL147336A0
(en)
|
1999-07-07 |
2002-08-14 |
Zymogenetics Inc |
Human cytokine receptor
|
US7431921B2
(en)
*
|
2000-04-14 |
2008-10-07 |
Maxygen Aps |
Interferon beta-like molecules
|
US7144574B2
(en)
*
|
1999-08-27 |
2006-12-05 |
Maxygen Aps |
Interferon β variants and conjugates
|
CZ2002521A3
(cs)
*
|
1999-08-27 |
2002-05-15 |
Maxygen Aps |
Nové molekuly podobné interferonu beta
|
US6531122B1
(en)
*
|
1999-08-27 |
2003-03-11 |
Maxygen Aps |
Interferon-β variants and conjugates
|
EP1224939A4
(de)
*
|
1999-10-12 |
2005-01-12 |
Santen Pharmaceutical Co Ltd |
Interferon komplex und dessen medizinische verwendung
|
CA2390292A1
(en)
*
|
1999-11-12 |
2001-05-25 |
Maxygen Holdings Ltd. |
Interferon gamma conjugates
|
US7230081B1
(en)
|
1999-11-12 |
2007-06-12 |
Maxygen Holdings, Ltd. |
Interferon gamma conjugates
|
JP2003534773A
(ja)
|
1999-12-03 |
2003-11-25 |
ザイモジェネティクス,インコーポレイティド |
ヒトサイトカイン受容体
|
ATE435033T1
(de)
|
2000-01-10 |
2009-07-15 |
Maxygen Holdings Ltd |
G-csf konjugate
|
RU2278123C2
(ru)
|
2000-02-11 |
2006-06-20 |
Максиджен Холдингз Лтд. |
Молекулы, подобные фактору vii или viia
|
JP2003533537A
(ja)
*
|
2000-05-16 |
2003-11-11 |
リポクセン テクノロジーズ リミテッド |
タンパク質の誘導体化
|
US20030211094A1
(en)
|
2001-06-26 |
2003-11-13 |
Nelsestuen Gary L. |
High molecular weight derivatives of vitamin k-dependent polypeptides
|
GB2380482A
(en)
*
|
2000-07-07 |
2003-04-09 |
Gennady P Samokhin |
Biologically active protein conjugates formed by first protecting active site
|
KR20030005204A
(ko)
*
|
2000-12-25 |
2003-01-17 |
가부시키가이샤 시세이도 |
교감신경 활성화 향료 조성물
|
US6867183B2
(en)
*
|
2001-02-15 |
2005-03-15 |
Nobex Corporation |
Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
|
US7060675B2
(en)
*
|
2001-02-15 |
2006-06-13 |
Nobex Corporation |
Methods of treating diabetes mellitus
|
WO2002066516A2
(en)
|
2001-02-20 |
2002-08-29 |
Zymogenetics, Inc. |
Antibodies that bind both bcma and taci
|
BR0207576A
(pt)
|
2001-02-27 |
2004-04-27 |
Maxygen Aps |
Variante glicosilada de um polipeptìdeo de interferon beta precursor (ifnb), processos de aumentar a glicosilação in vivo de uma molécula de ifnb precursora, de produzir uma molécula de ifnb glicosilada, para preparar uma variante conjugada e de tratar um mamìfero com esclerose múltiplam composição farmacêutica, molécula de ifnb variante, sequência de nucleotìdeo, vetor de expressão, célula hospedeira de glicosilação conjugado, e, uso de um conjugado
|
WO2002070655A2
(en)
|
2001-03-02 |
2002-09-12 |
Zymogenetics, Inc. |
Mouse cytokine receptor
|
US7038015B2
(en)
*
|
2001-04-06 |
2006-05-02 |
Maxygen Holdings, Ltd. |
Interferon gamma polypeptide variants
|
US6958388B2
(en)
|
2001-04-06 |
2005-10-25 |
Maxygen, Aps |
Interferon gamma polypeptide variants
|
US6835802B2
(en)
*
|
2001-06-04 |
2004-12-28 |
Nobex Corporation |
Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
|
US7713932B2
(en)
|
2001-06-04 |
2010-05-11 |
Biocon Limited |
Calcitonin drug-oligomer conjugates, and uses thereof
|
US6828297B2
(en)
|
2001-06-04 |
2004-12-07 |
Nobex Corporation |
Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US6713452B2
(en)
*
|
2001-06-04 |
2004-03-30 |
Nobex Corporation |
Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US6858580B2
(en)
*
|
2001-06-04 |
2005-02-22 |
Nobex Corporation |
Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US6828305B2
(en)
*
|
2001-06-04 |
2004-12-07 |
Nobex Corporation |
Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US7166571B2
(en)
*
|
2001-09-07 |
2007-01-23 |
Biocon Limited |
Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
|
US7196059B2
(en)
*
|
2001-09-07 |
2007-03-27 |
Biocon Limited |
Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
|
US6913903B2
(en)
|
2001-09-07 |
2005-07-05 |
Nobex Corporation |
Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
|
US7030082B2
(en)
*
|
2001-09-07 |
2006-04-18 |
Nobex Corporation |
Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith
|
US6770625B2
(en)
|
2001-09-07 |
2004-08-03 |
Nobex Corporation |
Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
|
US7312192B2
(en)
*
|
2001-09-07 |
2007-12-25 |
Biocon Limited |
Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
|
KR100480430B1
(ko)
*
|
2001-12-04 |
2005-04-06 |
선바이오(주) |
인터페론-베타와 폴리에틸렌글리콜 유도체의 배합체
|
AU2002346686A1
(en)
*
|
2001-12-07 |
2003-06-23 |
Intermune, Inc. |
Compositions and method for treating hepatitis virus infection
|
EP1476181B1
(de)
*
|
2002-01-18 |
2016-03-23 |
Biogen MA Inc. |
Polyalkylen-polymerverbindungen und ihre verwendung
|
EP1496925A4
(de)
*
|
2002-04-11 |
2007-05-30 |
Zymogenetics Inc |
Verwendung von interleukin-24 zur behandlung des ovarialkarzinoms
|
EP1497415B1
(de)
|
2002-04-19 |
2010-12-29 |
ZymoGenetics, L.L.C. |
Verfahren zum nachweis oder zur modulierung der wechselwirkung eines cytokinrezeptors mit seinem ligand
|
UA86744C2
(en)
|
2002-06-21 |
2009-05-25 |
Ново Нордиск Хэлс Кеа Аг |
Pegylated factor vii glycoforms
|
DE14169110T1
(de)
|
2002-06-28 |
2022-05-12 |
Centre National De La Recherche Scientifique -Cnrs- |
Modifizierte 2'- und 3'-Nukleosid-Prodrugs zur Behandlung von Flaviridae-Infektionen
|
CA2491178A1
(en)
*
|
2002-07-03 |
2004-01-15 |
Maxygen Holdings Ltd. |
Full-length interferon gamma polypeptide variants
|
US20040062748A1
(en)
|
2002-09-30 |
2004-04-01 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
US8129330B2
(en)
*
|
2002-09-30 |
2012-03-06 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
|
US20040175359A1
(en)
*
|
2002-11-12 |
2004-09-09 |
Desjarlais John Rudolph |
Novel proteins with antiviral, antineoplastic, and/or immunomodulatory activity
|
TWI364295B
(en)
*
|
2002-12-26 |
2012-05-21 |
Mountain View Pharmaceuticals |
Polymer conjugates of cytokines, chemokines, growth factors, polypeptide hormones and antagonists thereof with preserved receptor-binding activity
|
AU2003303635B2
(en)
*
|
2002-12-26 |
2009-07-23 |
Mountain View Pharmaceuticals, Inc. |
Polymer conjugates of interferon-beta with enhanced biological potency
|
BRPI0408946A
(pt)
*
|
2003-03-28 |
2006-04-04 |
Biopolymed Inc |
material biologicamente ativo conjugado com polìmero biocompatìvel com complexo 1:1, seu processo de preparação e composição farmacêutica compreendendo o mesmo
|
US7429572B2
(en)
|
2003-05-30 |
2008-09-30 |
Pharmasset, Inc. |
Modified fluorinated nucleoside analogues
|
ES2303132T3
(es)
|
2003-08-07 |
2008-08-01 |
Zymogenetics, Inc. |
Preparaciones homogeneas de il-29.
|
DE602004029173D1
(de)
|
2003-10-10 |
2010-10-28 |
Novo Nordisk As |
Il-21-derivate
|
EP2641611A3
(de)
|
2003-10-17 |
2013-12-18 |
Novo Nordisk A/S |
Kombinationstherapie
|
CN103212084B
(zh)
|
2003-11-13 |
2018-07-13 |
韩美科学株式会社 |
含有免疫球蛋白fc区作为载体的药物组合物
|
JP2007519422A
(ja)
|
2004-02-02 |
2007-07-19 |
アンブレツクス・インコーポレイテツド |
修飾されたヒト四螺旋バンドルポリペプチド及びそれらの使用
|
WO2005084303A2
(en)
*
|
2004-03-01 |
2005-09-15 |
Enzon Pharmaceuticals, Inc. |
Interferon-beta polymer conjugates
|
MXPA06014684A
(es)
|
2004-06-18 |
2007-02-12 |
Ambrx Inc |
Novedosos polipeptidos de enlace antigeno y sus usos.
|
EP2626368B1
(de)
*
|
2004-07-19 |
2016-12-21 |
Biocon Limited |
Insulinoligomerkonjugate, Formulierungen und Verwendungen davon
|
CN101023094B
(zh)
*
|
2004-07-21 |
2011-05-18 |
法莫赛特股份有限公司 |
烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
|
WO2006012644A2
(en)
|
2004-07-29 |
2006-02-02 |
Zymogenetics, Inc. |
Use of il-28 and il-29 to treat cancer
|
JP4971160B2
(ja)
|
2004-08-12 |
2012-07-11 |
シェーリング コーポレイション |
安定するpeg化インターフェロン処方物
|
WO2006031725A2
(en)
|
2004-09-14 |
2006-03-23 |
Pharmasset, Inc. |
Preparation of 2'fluoro-2'- alkyl- substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives
|
ATE541934T1
(de)
|
2004-12-22 |
2012-02-15 |
Ambrx Inc |
Zusammensetzungen von aminoacyl-trna-synthetase und verwendungen davon
|
AU2005322019B2
(en)
|
2004-12-22 |
2010-08-26 |
Ambrx, Inc. |
Formulations of human growth hormone comprising a non-naturally encoded amino acid
|
BRPI0519430A2
(pt)
|
2004-12-22 |
2009-02-10 |
Ambrx Inc |
hormânio do crescimento humano modificado
|
SG161210A1
(en)
|
2004-12-22 |
2010-05-27 |
Ambrx Inc |
Methods for expression and purification of recombinant human growth hormone
|
US7365127B2
(en)
*
|
2005-02-04 |
2008-04-29 |
Enzon Pharmaceuticals, Inc. |
Process for the preparation of polymer conjugates
|
AU2006212807A1
(en)
|
2005-02-08 |
2006-08-17 |
Zymogenetics, Inc. |
Anti-IL-20, anti-IL-22 and anti-IL-22RA antibodies and binding partners and methods of using in inflammation
|
KR100754667B1
(ko)
|
2005-04-08 |
2007-09-03 |
한미약품 주식회사 |
비펩타이드성 중합체로 개질된 면역글로불린 Fc 단편 및이를 포함하는 약제학적 조성물
|
US20070054360A1
(en)
|
2005-05-12 |
2007-03-08 |
Zeren Gao |
Compositions and methods for modulating immune responses
|
KR20080026135A
(ko)
|
2005-06-03 |
2008-03-24 |
암브룩스, 인코포레이티드 |
개선된 인간 인터페론 분자 및 이의 용도
|
EP1893240A2
(de)
*
|
2005-06-13 |
2008-03-05 |
Nastech Pharmaceutical Company Inc. |
Transmukosale abgabe von peptid-derivaten
|
EP2360170A3
(de)
|
2005-06-17 |
2012-03-28 |
Novo Nordisk Health Care AG |
Selektive Reduktion und Derivatisierung von Proteinen die mindestens ein nicht-natives Cystein enthalten
|
CA2621623A1
(en)
|
2005-09-28 |
2007-04-05 |
Zymogenetics, Inc. |
Il-17a and il-17f antagonists and methods of using the same
|
EP2339014B1
(de)
|
2005-11-16 |
2015-05-27 |
Ambrx, Inc. |
Verfahren und Zusammensetzungen mit nichtnatürlichen Aminosäuren
|
WO2007093594A1
(en)
*
|
2006-02-14 |
2007-08-23 |
Novo Nordisk Health Care Ag |
Coupling of polypeptides at the c-terminus
|
CN103030801B
(zh)
|
2006-02-21 |
2015-07-22 |
尼克塔治疗公司 |
嵌段可降解聚合物及由其制备的轭合物
|
WO2007130453A2
(en)
|
2006-05-02 |
2007-11-15 |
Allozyne, Inc. |
Non-natural amino acid substituted polypeptides
|
US20080096819A1
(en)
*
|
2006-05-02 |
2008-04-24 |
Allozyne, Inc. |
Amino acid substituted molecules
|
US20090252720A1
(en)
|
2006-05-24 |
2009-10-08 |
Novo Nordisk Health Care Ag |
Prolonged FIX Analogues and Derivatives
|
AR078117A1
(es)
|
2006-06-20 |
2011-10-19 |
Protech Pharma S A |
Una muteina recombinante del interferon alfa humano glicosilado, un gen que codifica para dicha muteina, un metodo de produccion de dicho gen, un metodo para obtener una celula eucariota productora de dicha muteina, un metodo para producir dicha muteina, un procedimiento para purificar dicha muteina
|
EP2069396B1
(de)
|
2006-09-08 |
2015-10-21 |
Ambrx, Inc. |
Modifiziertes polypeptid oder fc-gerüste aus humanem plasma und ihre verwendung
|
US8420792B2
(en)
|
2006-09-08 |
2013-04-16 |
Ambrx, Inc. |
Suppressor tRNA transcription in vertebrate cells
|
NZ574721A
(en)
|
2006-09-08 |
2012-02-24 |
Ambrx Inc |
Hybrid suppressor trna for vertebrate cells
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
BRPI0809583B1
(pt)
|
2007-03-30 |
2022-02-22 |
Ambrx, Inc |
Polipeptídeo fgf-21 modificado, composição compreendendo o mesmo, método para produzir o referido polipetídeo fgf-21 e célula compreendendo um polinucleotídeo
|
CA2685596A1
(en)
|
2007-05-02 |
2008-11-13 |
Ambrx, Inc. |
Modified interferon beta polypeptides and their uses
|
US7625555B2
(en)
|
2007-06-18 |
2009-12-01 |
Novagen Holding Corporation |
Recombinant human interferon-like proteins
|
CA2707840A1
(en)
|
2007-08-20 |
2009-02-26 |
Allozyne, Inc. |
Amino acid substituted molecules
|
ES2629440T5
(es)
|
2007-10-04 |
2020-11-20 |
Zymogenetics Inc |
zB7H6 miembro de la familia B7 y composiciones y métodos relacionados
|
AU2008313248B2
(en)
*
|
2007-10-16 |
2012-04-26 |
Biocon Limited |
An orally administerable solid pharmaceutical composition and a process thereof
|
NZ603812A
(en)
|
2007-11-20 |
2014-06-27 |
Ambrx Inc |
Modified insulin polypeptides and their uses
|
SG188143A1
(en)
|
2008-02-08 |
2013-03-28 |
Ambrx Inc |
Modified leptin polypeptides and their uses
|
TW200946541A
(en)
|
2008-03-27 |
2009-11-16 |
Idenix Pharmaceuticals Inc |
Solid forms of an anti-HIV phosphoindole compound
|
KR20220035504A
(ko)
|
2008-04-30 |
2022-03-22 |
이뮤노젠 아이엔씨 |
가교제 및 그 용도
|
US8173621B2
(en)
*
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
JP2011526154A
(ja)
|
2008-06-27 |
2011-10-06 |
ザイモジェネティクス, インコーポレイテッド |
可溶性ハイブリッドFcγレセプターおよび関連する方法
|
EA020766B1
(ru)
|
2008-07-08 |
2015-01-30 |
Борд Оф Риджентс, Дзе Юниверсити Оф Техас Систем |
Ингибиторы пролиферации и активации переносчика сигнала и активатора транскрипции (stats)
|
JP5563572B2
(ja)
|
2008-07-23 |
2014-07-30 |
ハンミ サイエンス カンパニー リミテッド |
三末端官能基を有する非ペプチド性重合体を用いた生理活性ポリペプチド薬物結合体
|
NZ591235A
(en)
|
2008-07-23 |
2012-07-27 |
Ambrx Inc |
Modified bovine g-csf polypeptides comprising non natural amino acid and their uses treating infections such as mastitis
|
PL2342223T3
(pl)
|
2008-09-26 |
2017-09-29 |
Ambrx, Inc. |
Zmodyfikowane polipeptydy zwierzęcej erytropoetyny i ich zastosowania
|
TR201802361T4
(tr)
|
2008-09-26 |
2018-03-21 |
Ambrx Inc |
Doğal olmayan amino asit replikasyonuna bağımlı mikroorganizmalar ve aşılar.
|
EP2376088B1
(de)
|
2008-12-23 |
2017-02-22 |
Gilead Pharmasset LLC |
6-O-Substituierte-2-Amino-Purin-Nukleosid-Phosphoramidate
|
EA019295B1
(ru)
|
2008-12-23 |
2014-02-28 |
Джилид Фармассет, Ллс. |
Соединения пуриновых нуклеозидов и способ их получения
|
US8551973B2
(en)
|
2008-12-23 |
2013-10-08 |
Gilead Pharmasset Llc |
Nucleoside analogs
|
US8618076B2
(en)
|
2009-05-20 |
2013-12-31 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
TWI576352B
(zh)
|
2009-05-20 |
2017-04-01 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
CN102458479B
(zh)
|
2009-06-04 |
2016-07-13 |
诺华公司 |
识别IgG结合位点的方法
|
CN104017063A
(zh)
|
2009-12-21 |
2014-09-03 |
Ambrx公司 |
经过修饰的猪促生长素多肽和其用途
|
NZ600361A
(en)
|
2009-12-21 |
2014-06-27 |
Ambrx Inc |
Modified bovine somatotropin polypeptides and their uses
|
CN102188715A
(zh)
*
|
2010-03-03 |
2011-09-21 |
北京双鹭药业股份有限公司 |
一类蛋白质多肽的复合分子及应用
|
JP6148013B2
(ja)
|
2010-03-05 |
2017-06-14 |
リグショスピタレト |
補体活性化のキメラ抑制分子
|
JP2013527145A
(ja)
|
2010-03-31 |
2013-06-27 |
ギリード・ファーマセット・エルエルシー |
リン含有活性化剤の立体選択的合成
|
PL3290428T3
(pl)
|
2010-03-31 |
2022-02-07 |
Gilead Pharmasset Llc |
Tabletka zawierająca krystaliczny (S)-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-diokso-3,4-dihydropirymidyn-1(2H)-ylo)-4-fluoro-3-hydroksy-4-metylotetrahydrofuran-2-ylo)metoksy)(fenoksy)fosforylo)amino)propanian izopropylu
|
EP2569331A1
(de)
|
2010-05-10 |
2013-03-20 |
Perseid Therapeutics LLC |
Polypeptid-inhibitoren von vla4
|
US9567386B2
(en)
|
2010-08-17 |
2017-02-14 |
Ambrx, Inc. |
Therapeutic uses of modified relaxin polypeptides
|
MY162837A
(en)
|
2010-08-17 |
2017-07-31 |
Ambrx Inc |
Modified relaxin polypeptides and their uses
|
AR083006A1
(es)
|
2010-09-23 |
2013-01-23 |
Lilly Co Eli |
Formulaciones para el factor estimulante de colonias de granulocitos (g-csf) bovino y variantes de las mismas
|
JP2013542983A
(ja)
*
|
2010-11-19 |
2013-11-28 |
ヴィーナス・レメディーズ・リミテッド |
標的薬物送達のための新規コンジュゲート
|
AR084044A1
(es)
|
2010-11-30 |
2013-04-17 |
Pharmasset Inc |
Compuestos 2’-espiro-nucleosidos
|
CN103930440A
(zh)
|
2011-07-01 |
2014-07-16 |
拜耳知识产权有限责任公司 |
松弛素融合多肽及其用途
|
US8889159B2
(en)
|
2011-11-29 |
2014-11-18 |
Gilead Pharmasset Llc |
Compositions and methods for treating hepatitis C virus
|
EP2859017B1
(de)
|
2012-06-08 |
2019-02-20 |
Sutro Biopharma, Inc. |
Antikörper mit nichtnatürlichen stellenspezifischen aminosäureresten, verfahren zu deren herstellung und verfahren zu deren verwendung
|
DK2863955T3
(en)
|
2012-06-26 |
2017-01-23 |
Sutro Biopharma Inc |
MODIFIED FC PROTEINS, INCLUDING LOCATION-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES THEREOF, METHODS OF PRODUCING ITS AND PROCEDURES FOR USE THEREOF
|
EP3584255B1
(de)
|
2012-08-31 |
2022-02-16 |
Sutro Biopharma, Inc. |
Modifizierte aminosäuren mit einer azidogruppe
|
US9764039B2
(en)
|
2013-07-10 |
2017-09-19 |
Sutro Biopharma, Inc. |
Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use
|
PL3650014T3
(pl)
|
2013-08-27 |
2022-01-31 |
Gilead Pharmasset Llc |
Preparat złożony dwóch związków przeciwwirusowych
|
US9840493B2
(en)
|
2013-10-11 |
2017-12-12 |
Sutro Biopharma, Inc. |
Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use
|
UY36370A
(es)
|
2014-10-24 |
2016-04-29 |
Bristol Myers Squibb Company Una Corporación Del Estado De Delaware |
Polipéptidos fgf-21 modificados y sus usos
|
HRP20231732T1
(hr)
|
2014-11-06 |
2024-03-15 |
Pharmaessentia Corporation |
Režim doziranja pegiliranog interferona
|
CN107226858B
(zh)
*
|
2016-03-23 |
2020-12-29 |
清华大学 |
干扰素高分子结合体ifn-pmpc的制备及其应用
|
US20210308277A1
(en)
|
2016-11-14 |
2021-10-07 |
Hangzhou Dac Biotech Co., Ltd. |
Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers
|
ES2963839T3
(es)
|
2017-02-08 |
2024-04-02 |
Bristol Myers Squibb Co |
Polipéptidos de relaxina modificados que comprenden un potenciador farmacocinético y usos de los mismos
|
HRP20240016T1
(hr)
|
2018-09-11 |
2024-03-29 |
Ambrx, Inc. |
Konjugati polipeptida interleukina-2 i njihove uporabe
|
CN113366015A
(zh)
|
2018-10-19 |
2021-09-07 |
Ambrx公司 |
白细胞介素-10多肽缀合物、其二聚体及其用途
|
BR112021015832A2
(pt)
|
2019-02-12 |
2022-01-18 |
Ambrx Inc |
Composições que contêm conjugados de anticorpo-agonista de tlr, métodos e usos dos mesmos
|
WO2021183832A1
(en)
|
2020-03-11 |
2021-09-16 |
Ambrx, Inc. |
Interleukin-2 polypeptide conjugates and methods of use thereof
|
CA3128035A1
(en)
|
2020-08-13 |
2022-02-13 |
Bioasis Technologies, Inc. |
Combination therapies for delivery across the blood brain barrier
|
AU2021327396A1
(en)
|
2020-08-20 |
2023-03-23 |
Ambrx, Inc. |
Antibody-TLR agonist conjugates, methods and uses thereof
|
AU2022249223A1
(en)
|
2021-04-03 |
2023-10-12 |
Ambrx, Inc. |
Anti-her2 antibody-drug conjugates and uses thereof
|