ATE307621T1 - Mit zellen beschichtete träger - Google Patents

Mit zellen beschichtete träger

Info

Publication number
ATE307621T1
ATE307621T1 AT98915561T AT98915561T ATE307621T1 AT E307621 T1 ATE307621 T1 AT E307621T1 AT 98915561 T AT98915561 T AT 98915561T AT 98915561 T AT98915561 T AT 98915561T AT E307621 T1 ATE307621 T1 AT E307621T1
Authority
AT
Austria
Prior art keywords
cell
wounds
enclosure
cells
coated supports
Prior art date
Application number
AT98915561T
Other languages
English (en)
Inventor
Riley S Rees
Cynthia Marcelo
Belinda Adamson
Lenore Rhodes
Berverly Marchant
William Lindblad
Robert Gilmont
Warren Garner
Cynthia Zuccaro
Thomas E Taddonio
Original Assignee
Univ Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan filed Critical Univ Michigan
Application granted granted Critical
Publication of ATE307621T1 publication Critical patent/ATE307621T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813Epithelial cells, e.g. keratinocytes, urothelial cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60Materials for use in artificial skin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0625Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0629Keratinocytes; Whole skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2531/00Microcarriers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • C12N2533/54Collagen; Gelatin
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T442/00Fabric [woven, knitted, or nonwoven textile or cloth, etc.]
    • Y10T442/20Coated or impregnated woven, knit, or nonwoven fabric which is not [a] associated with another preformed layer or fiber layer or, [b] with respect to woven and knit, characterized, respectively, by a particular or differential weave or knit, wherein the coating or impregnation is neither a foamed material nor a free metal or alloy layer
    • Y10T442/2525Coating or impregnation functions biologically [e.g., insect repellent, antiseptic, insecticide, bactericide, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Botany (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Fuel Cell (AREA)
AT98915561T 1997-04-16 1998-04-15 Mit zellen beschichtete träger ATE307621T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/840,804 US5972332A (en) 1997-04-16 1997-04-16 Wound treatment with keratinocytes on a solid support enclosed in a porous material
PCT/US1998/007480 WO1998046082A1 (en) 1997-04-16 1998-04-15 Cell-coated supports

Publications (1)

Publication Number Publication Date
ATE307621T1 true ATE307621T1 (de) 2005-11-15

Family

ID=25283281

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98915561T ATE307621T1 (de) 1997-04-16 1998-04-15 Mit zellen beschichtete träger

Country Status (7)

Country Link
US (6) US5972332A (de)
EP (2) EP0975226B1 (de)
AT (1) ATE307621T1 (de)
AU (1) AU6971198A (de)
DE (2) DE69832054T2 (de)
ES (2) ES2292034T3 (de)
WO (1) WO1998046082A1 (de)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6528483B2 (en) 1995-06-07 2003-03-04 André Beaulieu Method of producing concentrated non-buffered solutions of fibronectin
US20030105007A1 (en) * 1995-06-07 2003-06-05 Andre Beaulieu PDGF-betabeta and fibronectin combined in a solid wound dressing for the treatment of wounds
US20020037566A1 (en) * 1997-04-16 2002-03-28 Rees Riley S. Cell-coated supports
US5972332A (en) * 1997-04-16 1999-10-26 The Regents Of The University Of Michigan Wound treatment with keratinocytes on a solid support enclosed in a porous material
US7056503B2 (en) * 1999-08-19 2006-06-06 Regents Of The University Of Michigan Enclosures housing cell-coated supports for treating tumors
US7700660B2 (en) * 2000-05-31 2010-04-20 Encelle, Inc. Method of treating chronic ulcers
US7144729B2 (en) 2000-09-01 2006-12-05 Dfb Pharmaceuticals, Inc. Methods and compositions for tissue regeneration
EP1345602B1 (de) 2000-11-30 2010-07-21 Novodermix International Limited Heilung von wunden
US6890343B2 (en) 2000-12-14 2005-05-10 Ensure Medical, Inc. Plug with detachable guidewire element and methods for use
US8083768B2 (en) * 2000-12-14 2011-12-27 Ensure Medical, Inc. Vascular plug having composite construction
US6730509B2 (en) * 2001-01-17 2004-05-04 Bioverse, Inc. Controlled release dispenser
US20080086792A1 (en) 2006-10-13 2008-04-17 Thomas Charles Kuracina Method and apparatus for diverting sweat, liquid, moisture or the like from an eye
NZ535136A (en) 2002-02-21 2006-03-31 Encelle Inc Immobilized bioactive hydrogel matrices as surface coatings
ATE521697T1 (de) * 2002-03-29 2011-09-15 Singapore Eye Res Inst Verfahren zum wachstum von menschlichen bindehautgewebeäquivalenten für die forschung, die klinische augenoberflächentransplantation und die geweberekonstruktion
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
SG172478A1 (en) * 2002-10-25 2011-07-28 Revance Therapeutics Inc Modulation of zinc levels to improve tissue properties
EP1845107B1 (de) 2003-03-28 2019-05-29 FUJIFILM Manufacturing Europe B.V. Wirkstofffreisetzungssystem umfassend RGD-angereicherte gelatineähnliche Proteine mit verstärkter Zellbindung
US7352036B2 (en) 2004-08-03 2008-04-01 Fairchild Semiconductor Corporation Semiconductor power device having a top-side drain using a sinker trench
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
US8673640B2 (en) * 2005-09-20 2014-03-18 National Institute For Materials Science Porous scaffold, method of producing the same and method of using the porous scaffold
US20070142762A1 (en) * 2005-12-16 2007-06-21 Eastman Kodak Company Wound dressing
CA2810522A1 (en) 2006-05-04 2007-11-15 Boehringer Ingelheim International Gmbh Polymorphs
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
EP1852108A1 (de) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG Zusammensetzungen von DPP-IV-Inhibitoren
US7319256B1 (en) 2006-06-19 2008-01-15 Fairchild Semiconductor Corporation Shielded gate trench FET with the shield and gate electrodes being connected together
US8685421B2 (en) * 2006-07-07 2014-04-01 Surmodics, Inc. Beaded wound spacer device
EP2082030A2 (de) * 2006-10-20 2009-07-29 Keracure, Inc. Vorrichtungen mit auf biegsamen trägern kultivierten zellen
KR100866577B1 (ko) * 2007-09-28 2008-11-03 삼성전기주식회사 인쇄회로기판의 층간 도통방법
US20090202609A1 (en) * 2008-01-06 2009-08-13 Keough Steven J Medical device with coating composition
EP2077118A1 (de) * 2008-01-07 2009-07-08 Gwo Rei Biomedical Technology Corp. Gerinnungsfähiges Konzentrat von Plättchenwachstumsfaktoren und Herstellungsverfahren dafür
AR071175A1 (es) 2008-04-03 2010-06-02 Boehringer Ingelheim Int Composicion farmaceutica que comprende un inhibidor de la dipeptidil-peptidasa-4 (dpp4) y un farmaco acompanante
BRPI0916997A2 (pt) 2008-08-06 2020-12-15 Boehringer Ingelheim International Gmbh Inibidor de dpp-4 e seu uso
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
JP2012512848A (ja) 2008-12-23 2012-06-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 有機化合物の塩の形態
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
BR112012012641A2 (pt) 2009-11-27 2020-08-11 Boehringer Ingelheim International Gmbh TRATAMENTO DE PACIENTES DIABÉTICOS GENOTIPADOS COM INIBIDORES DE DPP-lVTAL COMO LINAGLIPTINA
WO2011084925A2 (en) 2010-01-05 2011-07-14 Cell Constructs, Inc. Biomaterials made from human hair
CA2797310C (en) 2010-05-05 2020-03-31 Boehringer Ingelheim International Gmbh Glp-1 receptor agonist and dpp-4 inhibitor combination therapy
AU2011268940B2 (en) 2010-06-24 2015-05-21 Boehringer Ingelheim International Gmbh Diabetes therapy
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
US8962636B2 (en) 2011-07-15 2015-02-24 Boehringer Ingelheim International Gmbh Substituted quinazolines, the preparation thereof and the use thereof in pharmaceutical compositions
KR20140097256A (ko) 2011-11-02 2014-08-06 할사이온, 인크. 상처 치료를 위한 방법들 및 조성물들
KR101335176B1 (ko) * 2011-12-12 2013-11-29 테고사이언스 (주) 상처 치유용 드레싱재제
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
EP2849755A1 (de) 2012-05-14 2015-03-25 Boehringer Ingelheim International GmbH Xanthinderivat als dpp-4-hemmer zur verwendung bei der behandlung von durch podozyten vermittelten erkrankungen und/oder des nephrotischen syndroms
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
EP2854824A1 (de) * 2012-05-25 2015-04-08 Boehringer Ingelheim International GmbH Verwendung von keratinozyten als einer biologisch aktive substanz in der behandlung von wunden wie diabätische wunden, gegebenenfalls in kombination mit einem dpp-4-hemmer
EP2908870B1 (de) 2012-10-16 2018-05-23 SurModics, Inc. Wundverpackungsvorrichtung und -verfahren
WO2015128453A1 (en) 2014-02-28 2015-09-03 Boehringer Ingelheim International Gmbh Medical use of a dpp-4 inhibitor
US10201457B2 (en) 2014-08-01 2019-02-12 Surmodics, Inc. Wound packing device with nanotextured surface
EP3132809A1 (de) * 2015-08-21 2017-02-22 Bioskinco GmbH Zusammensetzung und produkte mit alterungszellen zur geweberegeneration
EP4233840A3 (de) 2016-06-10 2023-10-18 Boehringer Ingelheim International GmbH Kombinationen aus linagliptin und metformin

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4576715A (en) * 1981-02-13 1986-03-18 Dresser Industries, Inc Membrane pack and method of making
US4997443A (en) * 1985-08-26 1991-03-05 Hana Biologics, Inc. Transplantable artificial tissue and process
CA1340581C (en) * 1986-11-20 1999-06-08 Joseph P. Vacanti Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices
US5015584A (en) * 1987-10-14 1991-05-14 Board Of Regents, The University Of Texas System Epidermal graft system
US5418154A (en) * 1987-11-17 1995-05-23 Brown University Research Foundation Method of preparing elongated seamless capsules containing biological material
IL94611A (en) * 1989-06-05 1994-12-29 Organogenesis Inc Medium for cell cultures containing insulin or growth factor similar to insulin, transferrin or iron ion, triiodothyronine or thyroxine and method of use
US5763266A (en) * 1989-06-15 1998-06-09 The Regents Of The University Of Michigan Methods, compositions and devices for maintaining and growing human stem and/or hematopoietics cells
WO1991001720A1 (en) * 1989-08-07 1991-02-21 Herman Wade Schlameus Composition and method of promoting hard tissue healing
US5529914A (en) * 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
BG51904A1 (en) * 1991-04-16 1993-11-15 Serdev Method foe epithelium cell covering of open wounds
RU2010028C1 (ru) * 1991-06-28 1994-03-30 Васильев Андрей Валентинович Способ восстановления кожного покрова у тяжелообожженных
US5545423A (en) * 1991-11-25 1996-08-13 Vivorx, Inc. Cytoprotective, biocompatible, retrievable macrocapsule containment systems for biologically active materials
US5269917A (en) * 1992-02-28 1993-12-14 Millipore Corporation Filtration apparatus having stress relief groove
GB9210574D0 (en) * 1992-05-18 1992-07-01 Ca Nat Research Council Biotherapeutic cell-coated microspheres for wound/burn and prothesis implant applications
US5512474A (en) * 1992-05-29 1996-04-30 Bsi Corporation Cell culture support containing a cell adhesion factor and a positively-charged molecule
EP0648264A4 (de) * 1992-06-03 1997-10-01 Univ Case Western Reserve Permanenter verband zur verabreichung von biologischen produkten.
IT231279Y1 (it) 1993-10-13 1999-08-02 Abate Luigi Elemento tubolare per la formazione di sacchetti per il confezionamento di prodotti sottovuoto
US5563068A (en) * 1994-04-21 1996-10-08 Genetic Therapy, Inc. Bioreactor
IL115728A0 (en) * 1994-10-25 1996-01-19 Boehringer Mannheim Gmbh Biomaterial containing epithelial cells and use thereof as a transplant
US5741685A (en) * 1995-06-07 1998-04-21 Children's Medical Center Corporation Parenchymal cells packaged in immunoprotective tissue for implantation
US5693332C1 (en) * 1995-08-11 2001-01-09 Univ California Human keratinocytes supported on a hydrophilic membrane and methods of using same to effect wound closure
US5972332A (en) * 1997-04-16 1999-10-26 The Regents Of The University Of Michigan Wound treatment with keratinocytes on a solid support enclosed in a porous material

Also Published As

Publication number Publication date
US20030124173A1 (en) 2003-07-03
DE69832054D1 (de) 2005-12-01
EP0975226A1 (de) 2000-02-02
EP1640024B1 (de) 2007-08-29
ES2292034T3 (es) 2008-03-01
EP0975226A4 (de) 2000-11-08
AU6971198A (en) 1998-11-11
DE69832054T2 (de) 2006-07-20
EP1640024A2 (de) 2006-03-29
ES2252830T3 (es) 2006-05-16
EP0975226B1 (de) 2005-10-26
EP1640024A3 (de) 2006-04-05
DE69838356T2 (de) 2008-05-21
US6197330B1 (en) 2001-03-06
US20010001039A1 (en) 2001-05-10
WO1998046082A1 (en) 1998-10-22
US20020015725A1 (en) 2002-02-07
US6299898B2 (en) 2001-10-09
US5972332A (en) 1999-10-26
US20010014674A1 (en) 2001-08-16
US6890552B2 (en) 2005-05-10
DE69838356D1 (de) 2007-10-11
US6440452B2 (en) 2002-08-27

Similar Documents

Publication Publication Date Title
ATE307621T1 (de) Mit zellen beschichtete träger
ATE380559T1 (de) Konjugate enthaltend ein antitumorales mittel und deren verwendung
DE69427716D1 (de) Klebeverband zur Blutstillung
PT1222941E (pt) Dispositivo medico flexivel
MX170492B (es) Vendaje adhesivo absorbente
DE69505176D1 (de) Poly(meth)acrylate-Hydrogelklebmittel
HU0001175D0 (en) Multilayered analytical device
NO20025608L (no) Kombinert SIS- og vakuumbandasje og fremgangsmåte
NO960724D0 (no) Middel for transdermal applisering inneholdende gestodenestere
BR9305783A (pt) Processo para preparar grânulos dispersiveis em água e grânulos dispersíveis em água
LU79534A1 (de) Mehrkanalsystem zur handhabung von immobilisierten biologisch-aktiven substanzen
DE69411030D1 (de) Osmotische und kapillare absorbierstruktur unterschiedlicher dichte und verfahren zu ihrer herstellung
NO984627L (no) Implanterbare, agarose-kollagenperler inneholdende celler som produserer et diffuserbart biologisk produkt og anvendelser derav
IT230274Y1 (it) Pannolone assorbente sagomato per incontinenza
IT1309588B1 (it) Cerotto con spessore sottile contenente betametasone ed acidoialuronico per il trattamento di psoriasi, dermatite, dermatosi.
DE69800433D1 (de) PSA Verfahren unter Verwendung eines Adsorptionmittels mit heterogener Kapazität und/oder Selektivität
FR2711056B1 (fr) Pansement adhésif absorbant.
ES2132027A1 (es) Desarrollo de una piel artificial mediante cultivo de queratinocitos sobre una base de fibrina y fibroblastos humanos y metodo de preparacion de esta piel para trasplante.
DE69807402D1 (de) Killer-T-Zell Aktivator und dessen Verwendung
ATE243252T1 (de) Pharmazeutische zusammensetzung enthaltend durch pim aktivierten nkt zellen, und ihr verwendung in der therapie
FI943441A (fi) Tris-karbamiinihapon estereitä: kolesterolin absorption ehkäisyaineita
DK407189D0 (da) Materiale, som indeholder formamidgruppeholdige (meth)acrylsyreestere, dets fremstilling og anvendelse
AU2003288363A1 (en) Support for receiving molecules having an activity and method for ensuring the presence of said molecules on said support
DE59712215D1 (de) Transdermales therapeutisches system mit einer östriol enthaltenden bisphosphatekombination
FR2634357B1 (fr) Pantoufle souple, lavable et sterilisable

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties