ATE301673T1 - Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand - Google Patents

Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand

Info

Publication number
ATE301673T1
ATE301673T1 AT99972682T AT99972682T ATE301673T1 AT E301673 T1 ATE301673 T1 AT E301673T1 AT 99972682 T AT99972682 T AT 99972682T AT 99972682 T AT99972682 T AT 99972682T AT E301673 T1 ATE301673 T1 AT E301673T1
Authority
AT
Austria
Prior art keywords
protein
known ligand
receptor coupled
rup3 receptor
human rup3
Prior art date
Application number
AT99972682T
Other languages
English (en)
Inventor
Ruoping Chen
Huong T Dang
Chen W Liaw
I-Lin Lin
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Application granted granted Critical
Publication of ATE301673T1 publication Critical patent/ATE301673T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99972682T 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand ATE301673T1 (de)

Applications Claiming Priority (24)

Application Number Priority Date Filing Date Title
US10921398P 1998-11-20 1998-11-20
US12041699P 1999-02-16 1999-02-16
US12185299P 1999-02-26 1999-02-26
US12394699P 1999-03-12 1999-03-12
US12394999P 1999-03-12 1999-03-12
US13656799P 1999-05-28 1999-05-28
US13713199P 1999-05-28 1999-05-28
US13643699P 1999-05-28 1999-05-28
US13643799P 1999-05-28 1999-05-28
US13712799P 1999-05-28 1999-05-28
US13643999P 1999-05-28 1999-05-28
US14144899P 1999-06-29 1999-06-29
US15655599P 1999-09-29 1999-09-29
US15665399P 1999-09-29 1999-09-29
US15663399P 1999-09-29 1999-09-29
US15663499P 1999-09-29 1999-09-29
US15728199P 1999-10-01 1999-10-01
US15728099P 1999-10-01 1999-10-01
US15728299P 1999-10-01 1999-10-01
US15729399P 1999-10-01 1999-10-01
US15729499P 1999-10-01 1999-10-01
US41704499A 1999-10-12 1999-10-12
US41676099A 1999-10-12 1999-10-12
PCT/US1999/023687 WO2000031258A2 (en) 1998-11-20 1999-10-13 Human orphan g protein-coupled receptors

Publications (1)

Publication Number Publication Date
ATE301673T1 true ATE301673T1 (de) 2005-08-15

Family

ID=27586698

Family Applications (3)

Application Number Title Priority Date Filing Date
AT05003040T ATE366815T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand
AT99972682T ATE301673T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand
AT07008841T ATE396400T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelte rezeptor rup3 ohne bekannte ligand

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT05003040T ATE366815T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT07008841T ATE396400T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelte rezeptor rup3 ohne bekannte ligand

Country Status (13)

Country Link
EP (8) EP2295574A1 (de)
JP (5) JP2003534767A (de)
KR (5) KR100926208B1 (de)
AT (3) ATE366815T1 (de)
AU (2) AU770056B2 (de)
CA (2) CA2645717A1 (de)
DK (3) DK1849866T3 (de)
ES (3) ES2289610T3 (de)
HK (2) HK1037675A1 (de)
IL (2) IL142538A0 (de)
NZ (3) NZ527622A (de)
PT (3) PT1584683E (de)
WO (1) WO2000031258A2 (de)

Families Citing this family (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69938015T2 (de) 1998-03-12 2009-01-15 Astellas Pharma Inc. Neue G Protein-gekoppelte Rezeptorproteine
US6071722A (en) * 1998-04-24 2000-06-06 Smithkline Beecham Corporation Nucleic acids encoding a G-protein coupled 7TM receptor (AXOR-1)
JP2002512780A (ja) * 1998-04-24 2002-05-08 スミスクライン ビーチャム コーポレーション 新規7tm受容体axor−2のクローニング
EP1155031A4 (de) * 1998-11-03 2002-11-27 Smithkline Beecham Corp Axor14, ein g-protein gekoppelter rezeptor
US7816492B2 (en) 1998-11-20 2010-10-19 Arena Pharmaceuticals, Inc. Human G protein-coupled receptors
USRE42190E1 (en) 1998-11-20 2011-03-01 Arena Pharmaceuticals, Inc. Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors
US20030017528A1 (en) 1998-11-20 2003-01-23 Ruoping Chen Human orphan G protein-coupled receptors
US6221660B1 (en) 1999-02-22 2001-04-24 Synaptic Pharmaceutical Corporation DNA encoding SNORF25 receptor
EP1157038A4 (de) * 1999-02-26 2005-01-19 Smithkline Beecham Corp KLONIERUNG EINES P2Y-äHNLICHEN 7TM-REZEPTORS (AXOR17)
US6620615B1 (en) 1999-04-23 2003-09-16 Curagen Corporation G-protein coupled receptor—encoding nucleic acids
WO2000078809A1 (en) * 1999-06-21 2000-12-28 Smithkline Beecham Corporation Axor16, a g protein coupled receptor
JP2003504054A (ja) * 1999-07-13 2003-02-04 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング G−タンパク質共役型受容体およびそのdna配列
CA2381437A1 (en) * 1999-07-30 2001-02-08 Merck Patent Gesellschaft Mit Beschraenkter Haftung G-protein coupled receptor and dna sequences thereof
CA2382889A1 (en) * 1999-08-27 2001-03-08 Takuya Watanabe Novel g protein-coupled receptor protein and dna thereof
US6998255B1 (en) 1999-09-24 2006-02-14 Solvay Pharmaceuticals B.V. Human G-protein coupled receptor
GB9923177D0 (en) * 1999-09-30 1999-12-01 Pfizer Ltd Novel polypeptide
US6204017B1 (en) 1999-10-07 2001-03-20 Schering Corporation Polynucleotide encoding a histamine receptor
GB9923890D0 (en) * 1999-10-08 1999-12-08 Pfizer Ltd Novel polypeptide
GB9923893D0 (en) * 1999-10-08 1999-12-08 Pfizer Ltd Novel polypeptide
GB9924956D0 (en) * 1999-10-21 1999-12-22 Pfizer Ltd Novel polypeptide
GB9924960D0 (en) * 1999-10-21 1999-12-22 Pfizer Ltd Novel polypeptide
CA2386509A1 (en) * 1999-10-27 2001-05-03 Pharmacia & Upjohn Company G protein-coupled receptors expressed in human brain
ES2291177T3 (es) * 1999-10-29 2008-03-01 Pfizer Inc. Polipeptido de tipo receptor acoplado a proteina g.
WO2001032864A2 (en) * 1999-11-03 2001-05-10 Merck Patent Gmbh Gpcr-kd5 polypeptides and dna sequences thereof
US6461836B1 (en) * 1999-11-05 2002-10-08 Smithkline Beecham Corporation Molecular cloning of a 7TM receptor (AxOR34) and screening methods thereof
CA2388865A1 (en) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Novel g protein-coupled receptors
US7029857B1 (en) 1999-12-17 2006-04-18 H. Lundbeck A/S Processes for obtaining compounds employing SNORF72 receptors
AU2398501A (en) * 1999-12-20 2001-07-03 Banyu Pharmaceutical Co., Ltd. Novel guanosine triphosphate-binding protein-coupled receptor protein, bg26
WO2001046454A1 (en) 1999-12-23 2001-06-28 Cor Therapeutics, Inc. P2y12 receptor
AU2230401A (en) * 1999-12-28 2001-07-09 Helix Research Institute Novel guanosine triphosphate-binding protein-coupled receptors, genes thereof and production and use of the same
GB0001700D0 (en) * 2000-01-25 2000-03-15 Glaxo Group Ltd Novel protein
US7138249B2 (en) 2000-02-04 2006-11-21 Takeda Pharmaceutical Company Limited Screening method
ES2283403T3 (es) * 2000-03-14 2007-11-01 Bayer Healthcare Ag Regulacion de la proteina similar al receptor de la lipoxina a4 humana.
US20040091863A1 (en) * 2000-03-17 2004-05-13 Shyam Ramakrishnan Regulation of human leukotriene b4-like g protein-coupled receptor
EP1270589A4 (de) * 2000-03-21 2004-09-29 Yamanouchi Pharma Co Ltd Neuer leukotrienb4 rezeptor
US20030087287A1 (en) * 2000-03-28 2003-05-08 Masanori Miwa Novel g-protein-coupled receptor protein and dna thereof
AU4467301A (en) * 2000-03-31 2001-10-08 Helix Research Institute Novel guanosine triphosphate-binding protein-coupled receptor gprv53, gene thereof and production and use of the same
WO2001077326A1 (fr) * 2000-04-12 2001-10-18 Takeda Chemical Industries, Ltd. Proteine receptrice couplee a la proteine g et son adn
EP1178110A1 (de) * 2000-08-01 2002-02-06 Aventis Pharma Deutschland GmbH EDG8 Rezeptor für Sphingosine 1-Phosphate , dessen Herstellung und Anwendung
PT1287133E (pt) * 2000-05-18 2007-03-30 Bayer Healthcare Ag Regulação do receptor acoplado à proteína g tipo dopamina humano
WO2002000719A2 (en) * 2000-06-23 2002-01-03 Tularik Inc. Human and mouse g-protein couipled receptors
WO2002000725A2 (en) * 2000-06-26 2002-01-03 Akzo Nobel N.V. G-protein coupled receptor org10
AU2001281933A1 (en) * 2000-06-30 2002-01-14 Ingenium Pharmaceuticals Ag Human g protein-coupled receptor igpcr17, and uses therof
AU2001271838A1 (en) 2000-07-06 2002-01-21 Bayer Corporation Human neuropeptide y-like g protein-coupled receptor
AU2001279232A1 (en) * 2000-08-09 2002-02-18 Millennium Pharmaceuticals, Inc. Methods for using 14266, a human g protein-coupled receptor
US6790608B2 (en) * 2000-09-20 2004-09-14 The Regents Of The University Of California Methods of identifying and ADP-glucose receptor ligand, agonist or antagonist
EP1331228B1 (de) 2000-11-01 2007-03-21 Astellas Pharma Inc. VERFAHREN ZUM SCREENEN EINES PLäTTCHENHEMMERS
CA2426037A1 (en) * 2000-11-07 2002-05-16 Paradigm Therapeutics Limited A "bach" g protein coupled receptor polypeptide and polynucleotide encoding this receptor
CN1549858A (zh) * 2000-11-27 2004-11-24 阿伦纳药品公司 内源和非内源型人g蛋白偶联受体
DE60125227T2 (de) 2000-12-01 2007-09-20 Astellas Pharma Inc. Verfahren zum screening von diabetes-heilverfahren
WO2002057311A2 (en) 2000-12-22 2002-07-25 University Of South Florida Sphingosine 1-phosphate receptor gene, sppr
WO2002052047A2 (en) * 2000-12-22 2002-07-04 Mergen Ltd. Methods for identifying g-protein coupled receptors associated with diseases
GB0100782D0 (en) * 2001-01-11 2001-02-21 Glaxo Group Ltd Assay
JPWO2002088355A1 (ja) * 2001-04-25 2004-08-19 藤沢薬品工業株式会社 新規なグアノシン三リン酸結合タンパク質共役型の受容体place6002312およびその遺伝子、並びにそれらの製造および用途
US20030096299A1 (en) 2001-07-09 2003-05-22 Valerie Wittamer Natural ligand of G protein coupled receptor ChemR23 and uses thereof
US7419658B2 (en) 2001-07-09 2008-09-02 Euroscreen S.A. Isolated ligand of ChemerinR
US7858755B2 (en) 2001-07-09 2010-12-28 Euroscreen S.A. Monoclonal antibodies that bind Chemerin polypeptide
US6946244B2 (en) 2001-08-07 2005-09-20 Euroscreen, S.A. Methods of identifying a ligand, an agonist, and an antagonist of G protein coupled receptor GPR86 (P2Y13)
CA2481508A1 (en) 2002-04-12 2003-10-23 Schering Corporation G-protein coupled receptor ligands and methods
AU2003261874A1 (en) * 2002-09-02 2004-03-29 Takeda Pharmaceutical Company Limited Adrenocortical hormone secretion controller
WO2004033687A1 (ja) * 2002-10-11 2004-04-22 Yamanouchi Pharmaceutical Co., Ltd. 腎不全治療薬をスクリーニングする方法
US7056685B1 (en) 2002-11-05 2006-06-06 Amgen Inc. Receptor ligands and methods of modulating receptors
WO2004058149A2 (en) 2002-12-20 2004-07-15 Merck & Co., Inc. 1-(amino)indanes and (1,2-dihydro-3-amino)-benzofurans, benzothiophenes and indoles
EP1599468B1 (de) 2003-01-14 2007-10-03 Arena Pharmaceuticals, Inc. 1,2,3-trisubstituierte aryl- und heteroarylderivate als modulatoren des metabolismus zur vorbeugung und behandlung von metabolismus-bedingten krankheiten wie diabetes oder hyperglykämie
US7083933B1 (en) 2003-05-09 2006-08-01 Prosidion Limited Methods for identification of modulators of OSGPR116 activity
EP1648488A4 (de) * 2003-06-27 2007-01-24 Tanox Inc In menschlichen mastzellen exprimiertes membranprotein
US7524638B1 (en) 2003-06-27 2009-04-28 Osi Pharmaceuticals, Inc. Methods for identification of modulators of OSGPR114 or OSGPR78 activity, and their use in the treatment of disease
DOP2006000008A (es) * 2005-01-10 2006-08-31 Arena Pharm Inc Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
GB0508990D0 (en) * 2005-05-03 2005-06-08 Novartis Ag Organic compounds
EP1971862B1 (de) 2006-04-11 2010-11-10 Arena Pharmaceuticals, Inc. Verfahren zur verwendung des gpr119-rezeptors zur identifizierung von verbindungen zur erhöhung der knochenmasse bei einer person
US7638541B2 (en) 2006-12-28 2009-12-29 Metabolex Inc. 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine
AU2008279447A1 (en) 2007-07-19 2009-01-29 Metabolex, Inc. N-azacyclic substituted pyrrole, pyrazole, imidazole, triazole and tetrazole derivatives as agonists of the RUP3 or GPR119 receptor for the treatment of diabetes and metabolic disorders
ES2499018T3 (es) 2007-09-20 2014-09-26 Irm Llc Compuestos y composiciones como moduladores de la actividad de GPR119
EP2146210A1 (de) 2008-04-07 2010-01-20 Arena Pharmaceuticals, Inc. Verfahren zur Verwendung eines AG-Protein-gekoppelten Rezeptors zur Identifikation von Peptid-YY (PPY)-Sekretagogen sowie Verbindungen zur Behandlung durch PYY modulierter Leiden
AR077642A1 (es) 2009-07-09 2011-09-14 Arena Pharm Inc Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo
ES2497566T3 (es) 2009-10-01 2014-09-23 Cymabay Therapeutics, Inc. Sales de tetrazol-1-il-fenoximetil-tiazol-2-il-piperidinil-pirimidina sustituida
US8791100B2 (en) 2010-02-02 2014-07-29 Novartis Ag Aryl benzylamine compounds
EP2556056A1 (de) 2010-04-06 2013-02-13 Arena Pharmaceuticals, Inc. Modulatoren des gpr119-rezeptors und behandlung von damit assoziierten erkrankungen
EP2585048B1 (de) 2010-06-23 2018-04-11 CymaBay Therapeutics, Inc. Zusammensetzungen von 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidin
KR101871011B1 (ko) 2010-09-22 2018-06-25 아레나 파마슈티칼스, 인크. Gpr119 수용체의 조절제 및 그와 관련된 장애의 치료
WO2012135570A1 (en) 2011-04-01 2012-10-04 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2012145361A1 (en) 2011-04-19 2012-10-26 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2012145603A1 (en) 2011-04-22 2012-10-26 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2012145604A1 (en) 2011-04-22 2012-10-26 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2012170702A1 (en) 2011-06-08 2012-12-13 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2013055910A1 (en) 2011-10-12 2013-04-18 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2014074668A1 (en) 2012-11-08 2014-05-15 Arena Pharmaceuticals, Inc. Modulators of gpr119 and the treatment of disorders related thereto
MX2017008925A (es) 2015-01-06 2017-10-11 Arena Pharm Inc Metodos de condiciones de tratamiento relacionadas con el receptor s1p1.
PT3310760T (pt) 2015-06-22 2022-11-10 Arena Pharm Inc Sal cristalino de l-arginina de ácido (r)-2-(7-(4-ciclopentil-3-(trifluorometil)benziloxi)-1,2,3,4-tetrahidrociclo-penta[b]indol-3-il)acético para utilização em distúrbios associados a recetores de s1p1
CN109862896A (zh) 2016-08-03 2019-06-07 西玛贝医药公司 用于治疗炎症性胃肠疾病或胃肠病症的氧亚甲基芳基化合物
JP2020524181A (ja) 2017-06-19 2020-08-13 アリーナ ファーマシューティカルズ, インコーポレイテッド Nafldおよびnashの治療のための化合物および方法

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000500658A (ja) * 1995-11-15 2000-01-25 シーオーアール・セラピューティックス・インコーポレーテッド 新規プリン受容体
JP2000505644A (ja) * 1996-01-11 2000-05-16 ヒューマン ジノーム サイエンシーズ,インコーポレイテッド ヒトgタンパク質結合レセプター
AU6017098A (en) * 1997-01-21 1998-08-07 Schering Corporation Mammalian chemokines; receptors; reagents; uses
US6221627B1 (en) * 1997-02-24 2001-04-24 Smithkline Beecham Corporation cDNA clone HDPB130 that encodes a novel human 7-transmembrane receptor
US5955303A (en) * 1997-03-06 1999-09-21 Incyte Pharmaceuticals, Inc. Human chemokine receptor-like protein
US6555339B1 (en) * 1997-04-14 2003-04-29 Arena Pharmaceuticals, Inc. Non-endogenous, constitutively activated human protein-coupled receptors
US6060272A (en) * 1997-05-07 2000-05-09 Human Genome Sciences, Inc. Human G-protein coupled receptors
EP0899332A3 (de) * 1997-08-15 2000-07-05 Smithkline Beecham Corporation G-Protein gekoppelter Rezeptor HFIAO41
CA2239255A1 (en) * 1997-10-23 1999-04-23 Smithkline Beecham Corporation Cdna clone hneaa81 that encodes a human 7-transmembrane receptor
US5932445A (en) * 1997-11-07 1999-08-03 Incyte Pharmaceuticals, Inc. Signal peptide-containing proteins
US6252056B1 (en) * 1997-11-11 2001-06-26 Ono Pharmaceutical Co., Ltd. Human lysophosphatidic acid receptor and use thereof
US6207412B1 (en) * 1997-11-13 2001-03-27 The Regents Of The University Of California Identification of a G protein-coupled receptor transcriptionally regulated by protein tyrosine kinase signaling in hematopoietic cells
WO1999042484A1 (en) * 1998-02-20 1999-08-26 Smithkline Beecham Corporation Fishboy, a g-protein coupled receptor
DE69938015T2 (de) * 1998-03-12 2009-01-15 Astellas Pharma Inc. Neue G Protein-gekoppelte Rezeptorproteine
WO1999052945A2 (en) * 1998-04-16 1999-10-21 Millenium Pharmaceuticals, Inc. NOVEL MOLECULES OF THE BGCKr-RELATED PROTEIN FAMILY AND USES THEREOF
SE9801455D0 (sv) * 1998-04-24 1998-04-24 Astra Pharma Inc New receptor
JP2002512780A (ja) * 1998-04-24 2002-05-08 スミスクライン ビーチャム コーポレーション 新規7tm受容体axor−2のクローニング
US6071722A (en) * 1998-04-24 2000-06-06 Smithkline Beecham Corporation Nucleic acids encoding a G-protein coupled 7TM receptor (AXOR-1)
CA2340334A1 (en) * 1998-08-19 2000-03-02 Millenium Pharmaceuticals, Inc. 14274 receptor, a g-protein coupled receptor related to the edg receptor family
CA2340457A1 (en) * 1998-08-20 2000-03-02 Millenium Pharmaceuticals, Inc. 14400 receptor, a g-protein coupled receptor
JP2002537757A (ja) * 1998-08-24 2002-11-12 アルファジーン・インコーポレイテッド 分泌タンパク質及びそれらをコードするポリヌクレオチド
AU5801099A (en) * 1998-09-02 2000-03-21 Millennium Pharmaceuticals, Inc. 14926 receptor, a novel g-protein coupled receptor
IL142153A0 (en) * 1998-10-13 2002-03-10 Arena Pharm Inc Non-endogenous, constitutively activated human g protein-coupled receptors
CA2344605A1 (en) * 1998-10-16 2000-04-27 Millennium Pharmaceuticals, Inc. G-protein coupled receptors
AU1242800A (en) * 1998-11-04 2000-05-22 Chiron Corporation Isolated vshk-1 receptor polypeptides and methods of use thereof
AU1712200A (en) * 1998-11-06 2000-05-29 Millennium Pharmaceuticals, Inc. G-protein coupled receptors, homologous to ebv-induced gpcr 2 (ebi-2). methods to seek for ligands thereof
US6221660B1 (en) * 1999-02-22 2001-04-24 Synaptic Pharmaceutical Corporation DNA encoding SNORF25 receptor
US6689866B1 (en) * 1999-03-09 2004-02-10 Curagen Corporation Polynucleotides and proteins encoded thereby
US6590938B1 (en) * 1999-09-30 2003-07-08 Conexant Systems, Inc. DCT domain conversion of a higher definition signal to lower definition signal
GB9923177D0 (en) * 1999-09-30 1999-12-01 Pfizer Ltd Novel polypeptide

Also Published As

Publication number Publication date
WO2000031258A3 (en) 2000-10-05
KR20070097564A (ko) 2007-10-04
KR100926208B1 (ko) 2009-11-09
ATE396400T1 (de) 2008-06-15
AU770056B2 (en) 2004-02-12
EP2295574A1 (de) 2011-03-16
ES2289610T3 (es) 2008-02-01
ATE366815T1 (de) 2007-08-15
EP1580271A2 (de) 2005-09-28
JP2008133300A (ja) 2008-06-12
DK1849866T3 (da) 2008-09-08
KR100963367B1 (ko) 2010-06-14
JP2007209352A (ja) 2007-08-23
AU2004202147A1 (en) 2004-06-10
EP1580271A3 (de) 2006-01-18
EP1780280A1 (de) 2007-05-02
EP2295572A1 (de) 2011-03-16
JP2003534767A (ja) 2003-11-25
KR20080104062A (ko) 2008-11-28
CA2348377C (en) 2008-12-02
EP1849866B1 (de) 2008-05-21
CA2645717A1 (en) 2000-06-02
PT1133559E (pt) 2005-10-31
PT1849866E (pt) 2008-08-28
EP2295573A1 (de) 2011-03-16
JP2004267216A (ja) 2004-09-30
JP2009298791A (ja) 2009-12-24
NZ511087A (en) 2004-01-30
KR20080024233A (ko) 2008-03-17
DK1133559T3 (da) 2006-04-10
EP1849866A2 (de) 2007-10-31
ES2243095T3 (es) 2005-11-16
ES2308759T3 (es) 2008-12-01
IL142538A0 (en) 2002-03-10
EP1584683B1 (de) 2007-07-11
PT1584683E (pt) 2007-10-17
EP1133559A2 (de) 2001-09-19
AU3790400A (en) 2000-06-13
IL142538A (en) 2010-11-30
EP1849866A3 (de) 2007-11-07
EP1584683A1 (de) 2005-10-12
KR100765039B1 (ko) 2007-10-09
EP1133559B1 (de) 2005-08-10
KR20010086040A (ko) 2001-09-07
KR100926209B1 (ko) 2009-11-09
CA2348377A1 (en) 2000-06-02
NZ527622A (en) 2005-03-24
HK1103763A1 (en) 2007-12-28
KR20080024234A (ko) 2008-03-17
DK1584683T3 (da) 2007-10-29
WO2000031258A2 (en) 2000-06-02
HK1037675A1 (en) 2002-02-15
NZ537625A (en) 2006-08-31

Similar Documents

Publication Publication Date Title
ATE301673T1 (de) Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand
DE69837606D1 (de) Cystein-reiche rezeptoren-train
CY1107339T1 (el) Mu-1, μελος της οικογενειας υποδοχεα κυτοκινης
ATE312819T1 (de) 4,4-biarylpiperidinederivate mit opioid-receptor- wirkung
HK1066018A1 (en) Soluble t cell receptor.
DE69709561T2 (de) Östrogen-Rezeptor
TR199600359A2 (tr) Adezyon reseptörü antagonistleri.
WO2002068600A3 (en) Endogenous and non-endogenous versions of human g protein-coupled receptors
DE69939053D1 (de) 2-arylethyl-(piperidin-4-ylmethyl)amine derivatives als muskarin-rezeptor antagonisten
WO2000050563A3 (en) G protein-coupled receptor resembling galanin receptors
DE50008020D1 (de) Substituierte pyrrolidin-2,3,4-trion-derivate wirksam als nmda-rezeptor-antagonisten
SE9702794D0 (sv) New compounds
CY1108264T1 (el) Ανθρωπινος ορφανος συζευγμενος σε g πρωτεϊνη υποδοχεας rup3
EP0943685A3 (de) Neuer G-Protein-gekoppelter Rezeptor aus menschlichem Gehirn
AU2002367629A8 (en) A novel human g-protein coupled receptor, hgprbmy14, related to the orphan gpcr, gpr73
DE69936550D1 (de) Menschliche, an ein G-Protein gekoppelter Rezeptor RUP3 ohne bekannten Ligand
NO20011779L (no) Ureidopiperidinderivater som selektive humane NK3 reseptor antagonister
AU2003210382A8 (en) Diagnostic for diseases associated with g-protein coupled receptor 105 (gpr105)
ATE310732T1 (de) 7-phenyl-1,4-diazepanderivate als neurokininrezeptorantagonisten
NO20035670L (no) En ny G-proteinkoplet reseptor, GAVE 3
GB0107802D0 (en) Novel g-protein coupled receptor
EP1676861A3 (de) Nicht-endogene, konstitutiv aktivierte, menschliche, mit G-Proteinen gekoppelte Rezeptoren
EP1082450A4 (de) Neuer g-protein gekoppelter rezeptor
AU8393001A (en) Novel g-protein coupled receptor
DE69926650D1 (de) Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand

Legal Events

Date Code Title Description
EENE Nomination of inventor
UEP Publication of translation of european patent specification

Ref document number: 1133559

Country of ref document: EP