DE69837606D1 - Cystein-reiche rezeptoren-train - Google Patents
Cystein-reiche rezeptoren-trainInfo
- Publication number
- DE69837606D1 DE69837606D1 DE69837606T DE69837606T DE69837606D1 DE 69837606 D1 DE69837606 D1 DE 69837606D1 DE 69837606 T DE69837606 T DE 69837606T DE 69837606 T DE69837606 T DE 69837606T DE 69837606 D1 DE69837606 D1 DE 69837606D1
- Authority
- DE
- Germany
- Prior art keywords
- train
- cystein rich
- receptors
- rich receptors
- cystein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153 or CD154
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5863197P | 1997-09-12 | 1997-09-12 | |
US58631P | 1997-09-12 | ||
US8442298P | 1998-05-06 | 1998-05-06 | |
US84422P | 1998-05-06 | ||
PCT/US1998/019030 WO1999013078A1 (en) | 1997-09-12 | 1998-09-11 | Cysteine rich receptors-train |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69837606D1 true DE69837606D1 (de) | 2007-05-31 |
DE69837606T2 DE69837606T2 (de) | 2008-02-14 |
Family
ID=26737837
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69837606T Expired - Lifetime DE69837606T2 (de) | 1997-09-12 | 1998-09-11 | Cystein-reiche rezeptoren-train |
Country Status (10)
Country | Link |
---|---|
US (4) | US7223852B2 (de) |
EP (2) | EP1012282B1 (de) |
JP (1) | JP4357738B2 (de) |
AT (1) | ATE360032T1 (de) |
AU (2) | AU9386398A (de) |
CA (1) | CA2301173C (de) |
DE (1) | DE69837606T2 (de) |
ES (1) | ES2286856T3 (de) |
HK (1) | HK1028417A1 (de) |
WO (2) | WO1999013078A1 (de) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7528239B1 (en) | 1997-02-13 | 2009-05-05 | Immunex Corporation | Receptor that binds trail |
US6072047A (en) | 1997-02-13 | 2000-06-06 | Immunex Corporation | Receptor that binds trail |
PT990703E (pt) * | 1997-02-27 | 2008-08-27 | Ono Pharmaceutical Co | Novo polipéptido, o adn que codifica o mesmo e a sua utilização |
US6342369B1 (en) | 1997-05-15 | 2002-01-29 | Genentech, Inc. | Apo-2-receptor |
WO1999013078A1 (en) | 1997-09-12 | 1999-03-18 | Biogen, Inc. | Cysteine rich receptors-train |
JP2002508934A (ja) * | 1997-12-29 | 2002-03-26 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Tnfレセプターに対して相同性を有する、新規な核酸およびポリペプチド |
JP2002528046A (ja) * | 1998-01-27 | 2002-09-03 | ミレニアム・フアーマシユーチカルズ・インコーポレーテツド | 新規レセプタースーパーファミリー分子およびそれについての用途 |
EP1710299A3 (de) * | 1998-12-30 | 2007-01-10 | Millennium Pharmaceuticals, Inc. | Sekretierte Proteine und dafür kodierende Polynukleotide |
AU2574200A (en) * | 1999-02-19 | 2000-09-04 | Toshio Kitamura | Novel tnf receptor-like proteins |
EP1210425B2 (de) | 1999-08-17 | 2015-06-17 | Biogen MA Inc. | Baff rezeptor (bcma), ein immunoregulatorisches mittel |
JP2003507064A (ja) * | 1999-08-25 | 2003-02-25 | ゲノム セラピューティックス コーポレーション | 膜結合タンパク質単離用膜貫通トラップ |
WO2001030850A1 (en) | 1999-10-22 | 2001-05-03 | Zymogenetics, Inc. | Umlr polypeptides |
GB9927681D0 (en) * | 1999-11-23 | 2000-01-19 | Glaxo Group Ltd | Protein |
WO2001058954A2 (en) * | 2000-02-11 | 2001-08-16 | Genetics Institute, Llc. | Trade molecules and uses related thereto |
US6900185B1 (en) | 2000-04-12 | 2005-05-31 | University Of Iowa Research Foundation | Method of inducing tumor cell apoptosis using trail/Apo-2 ligand gene transfer |
US7476383B2 (en) | 2000-05-02 | 2009-01-13 | The Uab Research Foundation | Antibody selective for DR4 and uses thereof |
TWI318983B (en) | 2000-05-02 | 2010-01-01 | Uab Research Foundation | An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof |
US7279160B2 (en) | 2000-05-02 | 2007-10-09 | The Uab Research Foundation | Combinations of DR5 antibodies and other therapeutic agents |
AU2001297702A1 (en) * | 2000-11-08 | 2002-10-15 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to trail receptors |
AU2002309647C1 (en) | 2001-05-25 | 2008-09-11 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to trail receptors |
US20190357827A1 (en) | 2003-08-01 | 2019-11-28 | Dexcom, Inc. | Analyte sensor |
CA2560742A1 (en) | 2004-03-23 | 2005-10-06 | Biogen Idec Ma Inc. | Receptor coupling agents and therapeutic uses thereof |
JP5060293B2 (ja) | 2004-08-03 | 2012-10-31 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 神経機能におけるtaj |
US8129124B2 (en) | 2005-02-02 | 2012-03-06 | The Uab Research Foundation | Agents and methods related to reducing resistance to apoptosis-inducing death receptor agonists |
JP4898126B2 (ja) * | 2005-02-28 | 2012-03-14 | 中外製薬株式会社 | Troyシグナルが阻害されたトランスジェニック非ヒト動物 |
PE20071101A1 (es) | 2005-08-31 | 2007-12-21 | Amgen Inc | Polipeptidos y anticuerpos |
US7888044B2 (en) | 2006-04-10 | 2011-02-15 | Trustees Of Boston University | Melanoma biomarker and methods of uses |
US9527915B2 (en) | 2009-11-05 | 2016-12-27 | The Uab Research Foundation | Treating basal-like genotype cancers |
US8703712B2 (en) | 2010-03-18 | 2014-04-22 | The Uab Research Foundation | Targeting cancer stem cells with DR5 agonists |
ES2675847T3 (es) | 2010-10-29 | 2018-07-13 | Daiichi Sankyo Company, Limited | Nuevo anticuerpo anti-DR5 |
JP6141827B2 (ja) | 2011-04-15 | 2017-06-07 | デックスコム・インコーポレーテッド | 検体を測定するシステムの作動方法及び該方法を実施するべく構成されたセンサシステム |
US9700253B2 (en) | 2012-03-16 | 2017-07-11 | Dexcom, Inc. | Systems and methods for processing analyte sensor data |
US20190120785A1 (en) | 2017-10-24 | 2019-04-25 | Dexcom, Inc. | Pre-connected analyte sensors |
US11331022B2 (en) | 2017-10-24 | 2022-05-17 | Dexcom, Inc. | Pre-connected analyte sensors |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5225538A (en) | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
US5965388A (en) | 1996-07-09 | 1999-10-12 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
WO2002000690A2 (en) | 2000-06-23 | 2002-01-03 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
WO1998030693A2 (en) * | 1997-01-14 | 1998-07-16 | Human Genome Sciences, Inc. | Tumor necrosis factor receptor 5 |
US6072047A (en) * | 1997-02-13 | 2000-06-06 | Immunex Corporation | Receptor that binds trail |
PT990703E (pt) * | 1997-02-27 | 2008-08-27 | Ono Pharmaceutical Co | Novo polipéptido, o adn que codifica o mesmo e a sua utilização |
ES2281126T3 (es) * | 1997-03-17 | 2007-09-16 | Human Genome Sciences, Inc. | Receptor 5 que contiene un dominio de muerte. |
WO1999011791A2 (en) | 1997-09-05 | 1999-03-11 | University Of Washington | Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents |
WO1999013078A1 (en) * | 1997-09-12 | 1999-03-18 | Biogen, Inc. | Cysteine rich receptors-train |
US20030027272A1 (en) * | 1997-09-18 | 2003-02-06 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
JP2001520033A (ja) | 1997-10-18 | 2001-10-30 | ジェネティックス・インスチチュート・インコーポレーテッド | 分泌蛋白およびそれらをコードするポリヌクレオチド |
JP2002508934A (ja) | 1997-12-29 | 2002-03-26 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Tnfレセプターに対して相同性を有する、新規な核酸およびポリペプチド |
WO1999033980A2 (en) | 1997-12-30 | 1999-07-08 | Chiron Corporation | Members of tnf and tnfr families |
JP2002528046A (ja) | 1998-01-27 | 2002-09-03 | ミレニアム・フアーマシユーチカルズ・インコーポレーテツド | 新規レセプタースーパーファミリー分子およびそれについての用途 |
EP1093516A2 (de) | 1998-07-06 | 2001-04-25 | Schering Corporation | Säugergenen; dendritische zellen prostaglandin- förmigen transporterprotein (dc-pgt), hdtea84, hsljd37r und rankl, hcc5 chemokine, deubiquitine 11 und 12 (dub11, dub12), md-1, md2 und cyclin e2, zugehörige reagenzien und verfahren |
JP2000098232A (ja) * | 1998-09-25 | 2000-04-07 | Canon Inc | 光学素子及びそれを用いた光学系 |
AU2574200A (en) | 1999-02-19 | 2000-09-04 | Toshio Kitamura | Novel tnf receptor-like proteins |
JP2004516227A (ja) | 1999-03-08 | 2004-06-03 | ジェネンテック・インコーポレーテッド | 免疫関連疾患を治療するための組成物と方法 |
GB9927681D0 (en) | 1999-11-23 | 2000-01-19 | Glaxo Group Ltd | Protein |
WO2001058954A2 (en) | 2000-02-11 | 2001-08-16 | Genetics Institute, Llc. | Trade molecules and uses related thereto |
AU6802801A (en) | 2000-03-01 | 2001-09-24 | Genentech Inc | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
AU6531101A (en) | 2000-06-02 | 2001-12-17 | Genentech Inc | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP1354040A2 (de) | 2000-07-20 | 2003-10-22 | Genentech, Inc. | Ausgeschiedene und transmembran-polypeptide und nukleinsäuren, welche für diese kodieren |
CA2416538A1 (en) | 2000-07-20 | 2002-01-31 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
AU2002328173A1 (en) | 2001-08-07 | 2003-02-24 | Genset S.A. | Omoxin agonists and antagonists for use in the treatment of metabolic disorders |
US8067664B2 (en) | 2003-12-16 | 2011-11-29 | Genentech, Inc. | PRO224 gene disruptions, and methods related thereto |
JP5060293B2 (ja) | 2004-08-03 | 2012-10-31 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 神経機能におけるtaj |
WO2007092777A2 (en) | 2006-02-02 | 2007-08-16 | Wyeth | Cloning, characterization, and application of tnfrsf19 in neurological disorders |
-
1998
- 1998-09-11 WO PCT/US1998/019030 patent/WO1999013078A1/en active IP Right Grant
- 1998-09-11 ES ES98944859T patent/ES2286856T3/es not_active Expired - Lifetime
- 1998-09-11 JP JP2000510863A patent/JP4357738B2/ja not_active Expired - Fee Related
- 1998-09-11 WO PCT/US1998/019029 patent/WO1999012963A2/en not_active Application Discontinuation
- 1998-09-11 AU AU93863/98A patent/AU9386398A/en not_active Abandoned
- 1998-09-11 EP EP98944859A patent/EP1012282B1/de not_active Expired - Lifetime
- 1998-09-11 EP EP98946966A patent/EP1012179A2/de not_active Withdrawn
- 1998-09-11 AT AT98944859T patent/ATE360032T1/de active
- 1998-09-11 CA CA2301173A patent/CA2301173C/en not_active Expired - Lifetime
- 1998-09-11 AU AU92303/98A patent/AU738688B2/en not_active Ceased
- 1998-09-11 DE DE69837606T patent/DE69837606T2/de not_active Expired - Lifetime
-
2000
- 2000-12-01 HK HK00107730A patent/HK1028417A1/xx not_active IP Right Cessation
-
2002
- 2002-11-22 US US10/303,502 patent/US7223852B2/en not_active Expired - Fee Related
-
2006
- 2006-04-04 US US11/396,907 patent/US7402658B2/en not_active Expired - Fee Related
-
2008
- 2008-05-30 US US12/130,740 patent/US7838639B2/en not_active Expired - Fee Related
-
2010
- 2010-11-22 US US12/951,761 patent/US20110158993A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1012282A1 (de) | 2000-06-28 |
US20030219860A1 (en) | 2003-11-27 |
WO1999013078A1 (en) | 1999-03-18 |
US20060233792A1 (en) | 2006-10-19 |
HK1028417A1 (en) | 2001-02-16 |
JP4357738B2 (ja) | 2009-11-04 |
AU738688B2 (en) | 2001-09-27 |
JP2002505843A (ja) | 2002-02-26 |
WO1999012963A3 (en) | 1999-05-06 |
ATE360032T1 (de) | 2007-05-15 |
US7402658B2 (en) | 2008-07-22 |
US7838639B2 (en) | 2010-11-23 |
CA2301173A1 (en) | 1999-03-18 |
CA2301173C (en) | 2015-04-14 |
EP1012282B1 (de) | 2007-04-18 |
US20110158993A1 (en) | 2011-06-30 |
US7223852B2 (en) | 2007-05-29 |
AU9230398A (en) | 1999-03-29 |
WO1999012963A2 (en) | 1999-03-18 |
AU9386398A (en) | 1999-03-29 |
DE69837606T2 (de) | 2008-02-14 |
ES2286856T3 (es) | 2007-12-01 |
EP1012179A2 (de) | 2000-06-28 |
US20090004188A1 (en) | 2009-01-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |