ATE294162T1 - Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid - Google Patents

Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid

Info

Publication number
ATE294162T1
ATE294162T1 AT02767318T AT02767318T ATE294162T1 AT E294162 T1 ATE294162 T1 AT E294162T1 AT 02767318 T AT02767318 T AT 02767318T AT 02767318 T AT02767318 T AT 02767318T AT E294162 T1 ATE294162 T1 AT E294162T1
Authority
AT
Austria
Prior art keywords
lercanidipine hydrochloride
solvates
crystalline forms
lercanidipine
hydrochloride
Prior art date
Application number
AT02767318T
Other languages
English (en)
Inventor
Amedeo Leonardi
Iasi Gianluca De
Fausto Bonifacio
Original Assignee
Recordati Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Ireland Ltd filed Critical Recordati Ireland Ltd
Application granted granted Critical
Publication of ATE294162T1 publication Critical patent/ATE294162T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02767318T 2001-08-06 2002-08-05 Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid ATE294162T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001MI001727A ITMI20011727A1 (it) 2001-08-06 2001-08-06 Solvati della lercanidipina cloridrato e nuove forme cristalline della lercanidipina cloridrato ottenute da essi
PCT/EP2002/008700 WO2003014085A1 (en) 2001-08-06 2002-08-05 Solvates of lercanidipine hydrochloride and new crystalline forms of lercanidipine hydrochloride

Publications (1)

Publication Number Publication Date
ATE294162T1 true ATE294162T1 (de) 2005-05-15

Family

ID=11448246

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02767318T ATE294162T1 (de) 2001-08-06 2002-08-05 Solvate von lercanidipin-hydrochlorid und kristalline formen von lercanidipin-hydrochlorid

Country Status (21)

Country Link
EP (1) EP1423367B1 (de)
JP (1) JP2005502648A (de)
KR (1) KR100912664B1 (de)
CN (1) CN100494175C (de)
AR (1) AR037230A1 (de)
AT (1) ATE294162T1 (de)
AU (1) AU2002331390B2 (de)
BR (1) BR0211738A (de)
DE (1) DE60203919D1 (de)
EA (1) EA200400279A1 (de)
ES (1) ES2209684T1 (de)
HR (1) HRP20040157A2 (de)
HU (1) HUP0401161A3 (de)
IL (2) IL153916A0 (de)
IT (1) ITMI20011727A1 (de)
MX (1) MXPA04001073A (de)
NO (1) NO20040479L (de)
PE (1) PE20030350A1 (de)
PL (1) PL369449A1 (de)
UY (1) UY27409A1 (de)
WO (1) WO2003014085A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100651212B1 (ko) 2004-10-27 2006-12-01 제일약품주식회사 무정형 레르카니디핀의 제조방법
AR052918A1 (es) 2005-02-25 2007-04-11 Recordati Ireland Ltd Clorhidrato de lercanidipina amorfo
BRPI0616169B8 (pt) 2005-09-16 2021-05-25 Glenmark Pharmaceuticals Ltd cloridrato de lercanidipina na forma polimorfa v, composição farmacêutica compreendendo dito composto e processos para preparação de cloridrato de lercanidipina
WO2008107797A2 (en) * 2007-03-05 2008-09-12 Actavis Group Ptc Ehf Lercanidipine hydrochloride polymorphs and an improved process for preparation of 1,1,n-trimethyl-n-(3,3-diphenylpropyl)-2-aminoethyl acetoacetate
WO2008136394A1 (ja) * 2007-04-27 2008-11-13 Ajinomoto Co., Inc. ラクタム化合物の製造方法及びその製造中間体
EP2585051B2 (de) 2010-06-23 2020-04-08 KRKA, tovarna zdravil, d.d., Novo mesto Pharmazeutische orale dosierformen mit lercandipin und enalapril und ihren pharmazeutisch akzeptablen salzen
WO2012085249A2 (en) 2010-12-24 2012-06-28 Krka, D.D., Novo Mesto Homogenous pharmaceutical oral dosage forms comprising lercanidipine and enalapril or their pharmaceutically acceptable salts

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8403866D0 (en) * 1984-02-14 1984-03-21 Recordati Chem Pharm Diphenylalkylaminoalkyl esters
US5912351A (en) * 1995-05-12 1999-06-15 Recordati, S.A. Chemical And Pharmaceutical Company Anhydrous 1,4-Dihydropyridines and salts thereof

Also Published As

Publication number Publication date
PL369449A1 (en) 2005-04-18
UY27409A1 (es) 2003-03-31
NO20040479L (no) 2004-02-03
ITMI20011727A1 (it) 2003-02-06
MXPA04001073A (es) 2005-02-17
JP2005502648A (ja) 2005-01-27
KR20040030932A (ko) 2004-04-09
EA200400279A1 (ru) 2004-06-24
AR037230A1 (es) 2004-11-03
KR100912664B1 (ko) 2009-08-17
CN100494175C (zh) 2009-06-03
HRP20040157A2 (en) 2004-08-31
EP1423367A1 (de) 2004-06-02
HUP0401161A3 (en) 2009-04-28
EP1423367B1 (de) 2005-04-27
AU2002331390B2 (en) 2008-06-05
PE20030350A1 (es) 2003-06-06
ES2209684T1 (es) 2004-07-01
WO2003014085A1 (en) 2003-02-20
BR0211738A (pt) 2004-09-28
ITMI20011727A0 (it) 2001-08-06
IL153916A0 (en) 2003-07-31
DE60203919D1 (de) 2005-06-02
HUP0401161A2 (hu) 2004-09-28
IL153916A (en) 2008-07-08
CN1538958A (zh) 2004-10-20

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties