ATE257480T1 - Bicyclische pyrrolylamide als glycogenphosphorylase-inhibitoren - Google Patents
Bicyclische pyrrolylamide als glycogenphosphorylase-inhibitorenInfo
- Publication number
- ATE257480T1 ATE257480T1 AT00308131T AT00308131T ATE257480T1 AT E257480 T1 ATE257480 T1 AT E257480T1 AT 00308131 T AT00308131 T AT 00308131T AT 00308131 T AT00308131 T AT 00308131T AT E257480 T1 ATE257480 T1 AT E257480T1
- Authority
- AT
- Austria
- Prior art keywords
- pyrrolylamides
- bicyclic
- glycogen phosphorylase
- phosphorylase inhibitors
- prodrugs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15714899P | 1999-09-30 | 1999-09-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE257480T1 true ATE257480T1 (de) | 2004-01-15 |
Family
ID=22562529
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00308131T ATE257480T1 (de) | 1999-09-30 | 2000-09-18 | Bicyclische pyrrolylamide als glycogenphosphorylase-inhibitoren |
Country Status (10)
Country | Link |
---|---|
US (3) | US6399601B1 (de) |
EP (1) | EP1088824B1 (de) |
JP (1) | JP3489819B2 (de) |
AT (1) | ATE257480T1 (de) |
BR (1) | BR0004582A (de) |
CA (1) | CA2321379A1 (de) |
DE (1) | DE60007592T2 (de) |
DK (1) | DK1088824T3 (de) |
ES (1) | ES2211454T3 (de) |
PT (1) | PT1088824E (de) |
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7223725B1 (en) * | 1997-11-14 | 2007-05-29 | Amylin Pharmaceuticals, Inc. | Exendin agonist compounds |
EP1066314B1 (de) | 1997-11-14 | 2007-12-26 | Amylin Pharmaceuticals, Inc. | Neuartige exendin agonisten |
EP1220672B1 (de) * | 1999-10-12 | 2006-10-04 | Lilly Icos LLC | Arzneimittel zur behandlung von neuropathien |
CO5271699A1 (es) | 2000-01-24 | 2003-04-30 | Pfizer Prod Inc | Procedimiento para el tratamiento de cardiomiopatia utilizando inhibidores de la glucogeno fosforilasa |
WO2001068136A1 (fr) * | 2000-03-17 | 2001-09-20 | Ajinomoto Co., Inc. | Medicaments permettant de traiter les complications du diabete et des neuropathies et utilisation de ces medicaments |
EP1136071A3 (de) * | 2000-03-22 | 2003-03-26 | Pfizer Products Inc. | Verwendung von Glykogen-Phosphorylase-Hemmern |
US20020165237A1 (en) * | 2000-08-11 | 2002-11-07 | Fryburg David Albert | Treatment of the insulin resistance syndrome |
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GB0021831D0 (en) * | 2000-09-06 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
ES2347137T3 (es) | 2000-10-20 | 2010-10-26 | Amylin Pharmaceuticals, Inc. | Tratamiento de miocardio hibernante y cardiomiopatia diabetica con un peptido gpl-1. |
US6683080B2 (en) * | 2001-02-02 | 2004-01-27 | Pfizer Inc. | Treatment of diabetes mellitus |
US20040198774A1 (en) * | 2001-08-23 | 2004-10-07 | Shinichi Ishii | Preventive and/or remedial agent for disease attributable to arteriosclerotic activity |
EP1452526A1 (de) * | 2001-10-29 | 2004-09-01 | Japan Tobacco Inc. | Indolverbindung und deren medizinische verwendung |
WO2003059372A2 (en) * | 2001-12-29 | 2003-07-24 | Novo Nordisk A/S | Combined use of a glp-1 compound and a modulator of diabetic late complications |
GB0205175D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
GB0205162D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
GB0205166D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
GB0205170D0 (en) * | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
GB0205165D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
GB0205176D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
JPWO2003091213A1 (ja) * | 2002-04-25 | 2005-09-02 | アステラス製薬株式会社 | 新規なアミド誘導体又はその塩 |
US7057046B2 (en) | 2002-05-20 | 2006-06-06 | Bristol-Myers Squibb Company | Lactam glycogen phosphorylase inhibitors and method of use |
US20040038864A1 (en) * | 2002-06-27 | 2004-02-26 | Per Balschmidt | Use of dimethyl sulfone as isotonicity agent |
AU2003272285A1 (en) | 2002-09-06 | 2004-03-29 | Janssen Pharmaceutica, N.V. | Thienopyrrolyl and furanopyrrolyl compounds and their use as histamine h4 receptor ligands |
GB0222909D0 (en) | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
GB0222912D0 (en) | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
EP1562899A2 (de) * | 2002-11-07 | 2005-08-17 | Pfizer Products Inc. | N-(indol-2-carbonyl)amide als antidiabetika |
US20060058310A1 (en) * | 2002-11-14 | 2006-03-16 | Yoshifumi Takenobu | Remedies for vertebral canal stenosis |
US7098235B2 (en) | 2002-11-14 | 2006-08-29 | Bristol-Myers Squibb Co. | Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds |
AU2003283216A1 (en) * | 2002-12-03 | 2004-06-23 | Novo Nordisk A/S | Combination treatment using exendin-4 and thiazolidinediones |
CN1964630A (zh) * | 2003-02-13 | 2007-05-16 | 耶希瓦大学艾伯塔·爱恩斯坦医学院 | 通过控制下丘脑的长链脂肪酰基-辅酶A(LC-CoA)的水平来调控食物摄取和葡萄糖产生 |
AU2004230316A1 (en) * | 2003-04-15 | 2004-10-28 | Pfizer Inc. | Alpha substituted carboxylic acid as PPAR modulators |
EP1620427A1 (de) * | 2003-04-17 | 2006-02-01 | Pfizer Products Inc. | Carbonsäureamid-derivate als antidiabetika |
MXPA05011702A (es) * | 2003-04-30 | 2006-01-23 | Pfizer Prod Inc | Agentes antidiabeticos. |
EA009215B1 (ru) * | 2003-05-21 | 2007-12-28 | Прозидион Лимитед | Ингибиторы гликогенфосфорилазы, представляющие собой амиды пирролопиридин-2-карбоновых кислот |
US7405210B2 (en) * | 2003-05-21 | 2008-07-29 | Osi Pharmaceuticals, Inc. | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase |
WO2004113345A1 (ja) * | 2003-06-20 | 2004-12-29 | Japan Tobacco Inc. | 縮合ピロール化合物及びその医薬用途 |
KR20060128976A (ko) | 2003-12-29 | 2006-12-14 | 세프라코 아이엔시. | 피롤 및 피라졸 디에이에이오 억제제 |
DE602005023965D1 (de) | 2004-03-08 | 2010-11-18 | Prosidion Ltd | Pyrrolopyridin-2-carbonsäurehydrazide als inhibitoren von glykogenphosphorylase |
US9737511B2 (en) * | 2004-05-24 | 2017-08-22 | Geoffrey C. GURTNER | Method of treating or preventing pathologic effects of acute increases in hyperglycemia and/or acute increases of free fatty acid flux |
WO2005115379A2 (en) * | 2004-05-24 | 2005-12-08 | New York University | Method of treating or preventing pathologic effects of acute increases in hyperglycemia and/or acute increases of free fatty acid flux |
WO2006041922A2 (en) * | 2004-10-08 | 2006-04-20 | Dara Biosciences, Inc. | Agents and methods for administration to the central nervous system |
US7365061B2 (en) | 2004-11-15 | 2008-04-29 | Bristol-Myers Squibb Company | 2-Amino-3-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors |
WO2006053274A2 (en) | 2004-11-15 | 2006-05-18 | Bristol-Myers Squibb Company | 2-amino-1-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors |
US7226942B2 (en) | 2004-11-15 | 2007-06-05 | Bristol-Myers Squibb Company | 2-amino-4-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors |
US7223786B2 (en) | 2004-11-15 | 2007-05-29 | Bristol-Myers Squibb Company | 2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors |
US20090298745A1 (en) * | 2004-12-02 | 2009-12-03 | Gerard Hugh Thomas | Treatment of Diabetes with Glycogen Phosphorylase Inhibitors |
JP4974057B2 (ja) * | 2005-01-31 | 2012-07-11 | 味の素株式会社 | 血糖降下剤を含有する、耐糖能異常、境界型糖尿病、インスリン抵抗性及び高インスリン血症の改善ないし治療用医薬組成物 |
US20070026079A1 (en) * | 2005-02-14 | 2007-02-01 | Louis Herlands | Intranasal administration of modulators of hypothalamic ATP-sensitive potassium channels |
EP1904066B1 (de) | 2005-07-06 | 2018-05-23 | Sunovion Pharmaceuticals Inc. | KOMBINATIONEN VON ESZOPICLON UND TRANS-4-(3,4-DICHLORPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE OR TRANS-4-(3,4-DICHLORPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPHTHALINAMIN ZUR BEHANDLUNG DER MENOPAUSE, Perimenopause UND VON KOGNITIVEN STÖRUNGEN |
JP5432526B2 (ja) | 2006-01-06 | 2014-03-05 | サノビオン ファーマシューティカルズ インク | モノアミン再取り込み阻害剤としてのシクロアルキルアミン |
WO2007081542A2 (en) | 2006-01-06 | 2007-07-19 | Sepracor Inc. | Tetralone-based monoamine reuptake inhibitors |
EP2013835B1 (de) | 2006-03-31 | 2015-11-04 | Sunovion Pharmaceuticals Inc. | Herstellung von chiralen amiden und aminen |
PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
WO2008005456A2 (en) * | 2006-06-30 | 2008-01-10 | Sepracor Inc. | Fused heterocyclic inhibitors of d-amino acid oxidase |
US20080058395A1 (en) * | 2006-06-30 | 2008-03-06 | Sepracor Inc. | Fused heterocyclic inhibitors of D-amino acid oxidase |
US7884124B2 (en) | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
US7579370B2 (en) * | 2006-06-30 | 2009-08-25 | Sepracor Inc. | Fused heterocycles |
WO2008047821A1 (fr) | 2006-10-18 | 2008-04-24 | Takeda Pharmaceutical Company Limited | Composé hétérocyclique fusionné |
US7902252B2 (en) | 2007-01-18 | 2011-03-08 | Sepracor, Inc. | Inhibitors of D-amino acid oxidase |
AU2008206039A1 (en) * | 2007-01-18 | 2008-07-24 | Sepracor Inc. | Inhibitors of D-amino acid oxidase |
CN103936605B (zh) | 2007-05-31 | 2017-09-01 | 赛诺维信制药公司 | 苯基取代的环烷胺作为一元胺再摄取抑制剂 |
WO2010017418A1 (en) * | 2008-08-07 | 2010-02-11 | Sepracor Inc. | Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase |
US10098857B2 (en) | 2008-10-10 | 2018-10-16 | The Board Of Trustees Of The Leland Stanford Junior University | Topical and transdermal delivery of HIF-1 modulators to prevent and treat chronic wounds |
US20100152200A1 (en) * | 2008-11-17 | 2010-06-17 | The Regents Of The University Of Michigan | Alphavirus inhibitors and uses thereof |
WO2011017634A2 (en) * | 2009-08-07 | 2011-02-10 | Sepracore Inc. | Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase |
US20150050371A1 (en) | 2012-03-09 | 2015-02-19 | Biotropics Malaysia Berhad | Extract Formulations of Rhodamnia Cinerea And Uses Thereof |
WO2017168174A1 (en) | 2016-04-02 | 2017-10-05 | N4 Pharma Uk Limited | New pharmaceutical forms of sildenafil |
WO2019055490A1 (en) | 2017-09-14 | 2019-03-21 | The Board Of Trustees Of The Leland Stanford Junior University | PACKAGING OF IRRADIED FABRIC FOR FAT GREETING RETENTION |
WO2019221192A1 (ja) | 2018-05-15 | 2019-11-21 | 旭化成株式会社 | アミノ酸アミノアルキルエステル又はその無機酸塩の製造方法 |
CN111468183A (zh) * | 2019-11-25 | 2020-07-31 | 天津大学 | 多氟代三芳基手性螺环磷酸催化剂及其制备方法、用途 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0031088A1 (de) * | 1979-12-19 | 1981-07-01 | Hoechst Aktiengesellschaft | Benzolsulfonylharnstoffe, Verfahren zu ihrer Herstellung, pharmazeutische Präparate auf Basis dieser Verbindungen sowie ihre Verwendung |
ES2081747B1 (es) * | 1993-09-07 | 1997-01-16 | Esteve Labor Dr | Amidas derivadas de tienopirroles, su preparacion y su aplicacion como medicamentos. |
FR2733750B1 (fr) * | 1995-05-03 | 1997-06-13 | Synthelabo | Derives de l'acide gamma-oxo-alpha-(phenylmethyl)-5,6- dihydro-4h-thieno(3,4-c)pyrrole-5-butanoique, leur preparation et leur application en therapeutique |
CA2223625C (en) * | 1995-06-06 | 2003-06-03 | Pfizer Inc. | Substituted n-(indole-2-carbonyl-) amides and derivatives as glycogen phosphorylase inhibitors |
US5952322A (en) * | 1996-12-05 | 1999-09-14 | Pfizer Inc. | Method of reducing tissue damage associated with non-cardiac ischemia using glycogen phosphorylase inhibitors |
DK0901786T3 (da) * | 1997-08-11 | 2007-10-08 | Pfizer Prod Inc | Faste farmaceutiske dispersioner med foröget biotilgængelighed |
US5939417A (en) * | 1998-10-19 | 1999-08-17 | Cell Pathways Inc | 1,3,6-trihydro-6-aza-3-oxapentalen-2-one derivatives for the treatment of neoplasia |
-
2000
- 2000-09-18 EP EP00308131A patent/EP1088824B1/de not_active Expired - Lifetime
- 2000-09-18 DE DE60007592T patent/DE60007592T2/de not_active Expired - Fee Related
- 2000-09-18 DK DK00308131T patent/DK1088824T3/da active
- 2000-09-18 ES ES00308131T patent/ES2211454T3/es not_active Expired - Lifetime
- 2000-09-18 AT AT00308131T patent/ATE257480T1/de not_active IP Right Cessation
- 2000-09-18 PT PT00308131T patent/PT1088824E/pt unknown
- 2000-09-20 JP JP2000285363A patent/JP3489819B2/ja not_active Expired - Fee Related
- 2000-09-27 US US09/670,759 patent/US6399601B1/en not_active Expired - Fee Related
- 2000-09-28 CA CA002321379A patent/CA2321379A1/en not_active Abandoned
- 2000-10-02 BR BR0004582-9A patent/BR0004582A/pt not_active IP Right Cessation
-
2002
- 2002-04-05 US US10/117,370 patent/US6576653B2/en not_active Expired - Fee Related
-
2003
- 2003-02-14 US US10/367,002 patent/US6828343B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1088824B1 (de) | 2004-01-07 |
JP3489819B2 (ja) | 2004-01-26 |
EP1088824A3 (de) | 2001-06-27 |
CA2321379A1 (en) | 2001-03-30 |
US6399601B1 (en) | 2002-06-04 |
JP2001131181A (ja) | 2001-05-15 |
PT1088824E (pt) | 2004-04-30 |
US6576653B2 (en) | 2003-06-10 |
US20030195361A1 (en) | 2003-10-16 |
DK1088824T3 (da) | 2004-04-13 |
ES2211454T3 (es) | 2004-07-16 |
DE60007592D1 (de) | 2004-02-12 |
US20020183369A1 (en) | 2002-12-05 |
US6828343B2 (en) | 2004-12-07 |
EP1088824A2 (de) | 2001-04-04 |
DE60007592T2 (de) | 2004-09-16 |
BR0004582A (pt) | 2001-04-17 |
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Legal Events
Date | Code | Title | Description |
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UEP | Publication of translation of european patent specification |
Ref document number: 1088824 Country of ref document: EP |
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REN | Ceased due to non-payment of the annual fee |