ATE220714T1 - Verfahren zur herstellung von proteinen - Google Patents

Verfahren zur herstellung von proteinen

Info

Publication number
ATE220714T1
ATE220714T1 AT94306587T AT94306587T ATE220714T1 AT E220714 T1 ATE220714 T1 AT E220714T1 AT 94306587 T AT94306587 T AT 94306587T AT 94306587 T AT94306587 T AT 94306587T AT E220714 T1 ATE220714 T1 AT E220714T1
Authority
AT
Austria
Prior art keywords
desired protein
producing proteins
producing
recovering
culture
Prior art date
Application number
AT94306587T
Other languages
English (en)
Inventor
Kazuaki Furukawa
Keijiro Sugimura
Kazuhiro Ohsuye
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of ATE220714T1 publication Critical patent/ATE220714T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT94306587T 1993-09-08 1994-09-07 Verfahren zur herstellung von proteinen ATE220714T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5257881A JPH0775593A (ja) 1993-09-08 1993-09-08 蛋白質の製造方法

Publications (1)

Publication Number Publication Date
ATE220714T1 true ATE220714T1 (de) 2002-08-15

Family

ID=17312486

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94306587T ATE220714T1 (de) 1993-09-08 1994-09-07 Verfahren zur herstellung von proteinen

Country Status (7)

Country Link
US (1) US5834249A (de)
EP (1) EP0649900B1 (de)
JP (1) JPH0775593A (de)
AT (1) ATE220714T1 (de)
CA (1) CA2131659A1 (de)
DE (1) DE69430975T2 (de)
ES (1) ES2176224T3 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001017514A1 (en) * 1999-09-03 2001-03-15 The Salk Institute For Biological Studies Modulation of gene expression by modulating histone acetylation
US6544957B2 (en) 2000-01-04 2003-04-08 The Johns Hopkins University Methods and reagents for facilitating transcription
GB0023983D0 (en) * 2000-09-29 2000-11-15 Prolifix Ltd Therapeutic compounds
JP4975941B2 (ja) * 2000-09-29 2012-07-11 トポターゲット ユーケー リミテッド （ｅ）−ｎ−ヒドロキシ−３−（３−スルファモイル−フェニル）アクリルアミド化合物及びその治療用途
JP2004509941A (ja) * 2000-09-29 2004-04-02 プロリフィクス　リミテッド Ｈｄａｃインヒビターとしてのアミド結合を含むカルバミン酸化合物
AU2002348474A1 (en) * 2001-10-18 2003-04-28 The Salk Institute For Biological Studies Methods of using deacetylase inhibitors to promote cell differentiation and regeneration
ATE399012T1 (de) * 2002-04-03 2008-07-15 Topotarget Uk Ltd Carbaminsäurederivate enthaltend eine piperazin verknüpfung als hdac-inhibitoren
WO2004065354A1 (en) 2003-01-17 2004-08-05 Topotarget Uk Limited Carbamic acid compounds comprising an ester or ketone linkage as hdac inhibitors
WO2004076386A2 (en) * 2003-02-25 2004-09-10 Topotarget Uk Limited Carbamic acid compounds comprising a bicyclic heteroaryl group as hdac inhibitors
US20070026012A1 (en) 2005-08-01 2007-02-01 Cornell Research Foundation, Inc. Compositions and methods for monitoring and altering protein folding and solubility
EP1917347B1 (de) 2005-08-22 2015-10-07 Cornell Research Foundation, Inc. Zusammensetzungen und verfahren zur analyse von proteinwechselwirkungen
EP2548030B1 (de) 2010-03-18 2015-05-27 Cornell University Engineering korrekt gefalteter antikörper mit membraninterner anzeige von twin-arginin-translokations-zwischenprodukten
US9051901B2 (en) 2011-06-07 2015-06-09 Ford Global Technologies, Llc Exhaust gas recirculation (EGR) system

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS215108B2 (en) * 1977-07-15 1982-07-30 Wellcome Found Method of making the interferrone
US4218478A (en) * 1979-01-05 1980-08-19 Ruiko Oiwa Trichostatin as an antiprotozoal agent
JPS5917960B2 (ja) * 1979-09-25 1984-04-24 住友ゴム工業株式会社 刻印用電気ごて
JPS5774093A (en) * 1980-10-27 1982-05-10 Ajinomoto Co Inc Method of increasing interferon production
JPS6018398B2 (ja) * 1982-10-29 1985-05-10 工業技術院長 インタ−フエロンの効率的生産法
JPS6018398A (ja) * 1984-06-12 1985-01-30 松下電器産業株式会社 電気鉛筆削り機
JPS61176523A (ja) * 1985-01-30 1986-08-08 Teruhiko Beppu 制癌剤
DE3767629D1 (de) * 1986-09-20 1991-02-28 Tasuku Honjo Menschlicher b-zellen-differenzierungsfaktor und verfahren zu dessen herstellung.
JPH01257492A (ja) * 1987-03-05 1989-10-13 Green Cross Corp:The 異種蛋白質の生産増強方法
JP2598050B2 (ja) * 1987-07-17 1997-04-09 サントリー株式会社 Ｃ−末端α−アミド化酵素
JPH01224381A (ja) * 1988-03-04 1989-09-07 Japan Tobacco Inc トリコスタチン酸、トリコスタチンａの新規な合成中間体、及びトリコスタチン酸、トリコスタチンａの製造方法。
JP2535398B2 (ja) * 1989-01-17 1996-09-18 サントリー株式会社 アミド化ペプチドの製造方法
JPH047648A (ja) * 1990-04-24 1992-01-13 Mitsubishi Electric Corp マイクロコンピュータ
JPH0532031A (ja) * 1991-05-23 1993-02-09 Tokyo Electric Co Ltd インクリボンカートリツジ
AU4190893A (en) * 1992-07-17 1994-01-20 Suntory Limited Megakaryocyte differentiation factor

Also Published As

Publication number Publication date
DE69430975D1 (de) 2002-08-22
CA2131659A1 (en) 1995-03-09
EP0649900A2 (de) 1995-04-26
JPH0775593A (ja) 1995-03-20
DE69430975T2 (de) 2003-01-23
ES2176224T3 (es) 2002-12-01
EP0649900A3 (de) 1996-07-03
US5834249A (en) 1998-11-10
EP0649900B1 (de) 2002-07-17

Similar Documents

Publication Publication Date Title
ATE406435T1 (de) Methoden zur züchtung von tierzellen
ATE189476T1 (de) Material und verfahren zur stark vermehrter sekretion von aminosäuren
DE59610898D1 (de) Verfahren zur herstellung von erythropoietin frei von tierischen proteinen
DE68925138D1 (de) Verfahren zur Herstellung von Proteinen durch Verwendung von CKS-Fusionsproteinen
DE69530242D1 (de) Verfahren zur Herstellung von Glutaminsäure durch Fermentation
ATE372383T1 (de) Verfahren zur herstellung von l-aminosäuren
DE59608743D1 (de) Verfahren zur herstellung von rekombinanten proteinen in e. coli mittels hochzelldichte-fermentation
DE19681532T1 (de) Verfahren zur Herstellung von L-Glutaminsäure durch Fermentation
DE69935978D1 (de) Kulturmedium zur kultivierung tierischer zellen und verfahren zur herstellung von proteinen durch dessen verwendung
ATE220714T1 (de) Verfahren zur herstellung von proteinen
DE3688336D1 (de) Verfahren zur herstellung von organischen saeuren unter verwendung von mikroorganismen.
DE69011880D1 (de) Verfahren zur Herstellung von L-Aminosäuren durch Fermentation.
DE69027098D1 (de) Verfahren zur fermentativen Herstellung von Diacetyl und Acetoin unter Verwendung von Milchsäurebakterien
DE3485336D1 (de) Verfahren zur expression von alpha-1-antitrypsin in bakterien und dessen verwendung in therapeutischen zusammensetzungen sowie vektoren und bakterien fuer ein solches verfahren und deren herstellung.
DE3862306D1 (de) Verfahren zur elektrochemischen herstellung von carbonsaeuren.
ATE204283T1 (de) Verfahren zur herstellung von 2,2- difluorketensilylacetalen und alpha,alpha-difluor-beta -silyloxy-1,3-dioxolan-4-propansäureestern
ATE154393T1 (de) Verfahren zur herstellung von trans-l-hydroxy- prolin
DE3575743D1 (de) Verfahren zur gewinnung von phenylalanin-dehydrogenase enthaltenden mikroorganismen und deren verwendung zur herstellung von l-alpha-aminosaeuren.
DE59606567D1 (de) Neuer Mikroorganismus, dessen Verwendung und Verfahren zur Herstellung von L-Alpha-Aminosäuren
DE59108128D1 (de) Verfahren zur Herstellung von Fremdproteinen in Streptomyceten
ATE180837T1 (de) Verfahren zur herstellung von häm-proteinen
DE68926922D1 (de) Verfahren zur Herstellung von L-alpha-Aminosäuren
DE3678552D1 (de) Verfahren zur herstellung von proteinen unter verwendung von transformierten milchsaeurebakterien.
DE59008683D1 (de) Verfahren zur hochzelldichte-fermentation von escherichia coli in einem rührkesselfermentor.
DE3677421D1 (de) Mikrobiologisches verfahren zur herstellung von menschlichem lysozym.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0649900

Country of ref document: EP

EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee