JPS5774093A - Method of increasing interferon production - Google Patents
Method of increasing interferon productionInfo
- Publication number
- JPS5774093A JPS5774093A JP55150440A JP15044080A JPS5774093A JP S5774093 A JPS5774093 A JP S5774093A JP 55150440 A JP55150440 A JP 55150440A JP 15044080 A JP15044080 A JP 15044080A JP S5774093 A JPS5774093 A JP S5774093A
- Authority
- JP
- Japan
- Prior art keywords
- dimethylsulfoxide
- cultivation
- cultured
- medium
- butyric acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE: Cells continuously producing interferon are cultured in a medium for mammalian cell culture containing glucocorticoid, butyric acid or dimethylsulfoxide to increase the production of the titled substance.
CONSTITUTION: A cell strain continuously producing interferon, obtained by transforming lymphocytes originating from human fetus or neonate with Epstein-Barr virus, such as UNCL is cultured in a medium for mammalian cell culture to which glucocorticoid, butyric acid or dimethylsulfoxide is added. The addition may be before the start of te cultivation, however, preferably 2 or 3 days after the start. The cultivation and isolation of the objective substance from the culture mixture are conducted in usual manners.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55150440A JPS5774093A (en) | 1980-10-27 | 1980-10-27 | Method of increasing interferon production |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55150440A JPS5774093A (en) | 1980-10-27 | 1980-10-27 | Method of increasing interferon production |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5774093A true JPS5774093A (en) | 1982-05-10 |
Family
ID=15496971
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55150440A Pending JPS5774093A (en) | 1980-10-27 | 1980-10-27 | Method of increasing interferon production |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5774093A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6062997A (en) * | 1983-09-17 | 1985-04-11 | Mochida Pharmaceut Co Ltd | Preparation of interferon |
JPS63503273A (en) * | 1986-03-14 | 1988-12-02 | セルテック リミテッド | Protein production by cell culture |
US5378612A (en) * | 1990-05-11 | 1995-01-03 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Culture medium for production of recombinant protein |
EP0649900A3 (en) * | 1993-09-08 | 1996-07-03 | Suntory Ltd | Process for production of protein. |
US5681718A (en) * | 1986-03-14 | 1997-10-28 | Celltech Limited | Methods for enhanced production of tissue plasminogen activator in cell culture using alkanoic acids or salts thereof |
-
1980
- 1980-10-27 JP JP55150440A patent/JPS5774093A/en active Pending
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6062997A (en) * | 1983-09-17 | 1985-04-11 | Mochida Pharmaceut Co Ltd | Preparation of interferon |
JPH0358717B2 (en) * | 1983-09-17 | 1991-09-06 | Mochida Pharm Co Ltd | |
JPS63503273A (en) * | 1986-03-14 | 1988-12-02 | セルテック リミテッド | Protein production by cell culture |
US5681718A (en) * | 1986-03-14 | 1997-10-28 | Celltech Limited | Methods for enhanced production of tissue plasminogen activator in cell culture using alkanoic acids or salts thereof |
US6228618B1 (en) | 1986-03-14 | 2001-05-08 | Alusuisse Holdings A.G. | Methods for enhanced production of tissue plasminogen activator in cell culture using alkanoic acids or salts thereof |
US6413746B1 (en) | 1986-03-14 | 2002-07-02 | Lonza Group, Ag | Production of proteins by cell culture |
US6660501B2 (en) | 1986-03-14 | 2003-12-09 | Lonza Group, Ag | Production of proteins by cell culture |
US5378612A (en) * | 1990-05-11 | 1995-01-03 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Culture medium for production of recombinant protein |
EP0649900A3 (en) * | 1993-09-08 | 1996-07-03 | Suntory Ltd | Process for production of protein. |
US5834249A (en) * | 1993-09-08 | 1998-11-10 | Suntory Limited | Process for production of protein |
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