US6586388B2
(en)
|
1988-04-08 |
2003-07-01 |
Stryker Corporation |
Method of using recombinant osteogenic protein to repair bone or cartilage defects
|
US5266683A
(en)
*
|
1988-04-08 |
1993-11-30 |
Stryker Corporation |
Osteogenic proteins
|
US6919308B2
(en)
|
1988-04-08 |
2005-07-19 |
Stryker Corporation |
Osteogenic devices
|
US5354557A
(en)
*
|
1988-04-08 |
1994-10-11 |
Stryker Corporation |
Osteogenic devices
|
US5693615A
(en)
*
|
1991-06-05 |
1997-12-02 |
The Procter & Gamble Company |
Therapeutic compositions for osteoinduction
|
KR100255415B1
(ko)
*
|
1991-06-25 |
2000-05-01 |
브루스 엠. 에이센 |
비엠피-9 조성물
|
ATE238417T1
(de)
*
|
1991-11-04 |
2003-05-15 |
Inst Genetics Llc |
Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung
|
KR100231640B1
(ko)
*
|
1993-05-12 |
1999-12-01 |
토마스 제이 데스로저 |
Bmp-10 조성물
|
EP2272959A1
(de)
*
|
1993-05-12 |
2011-01-12 |
Genetics Institute, LLC |
BMP-11 Zusammenstellungen
|
US5399677A
(en)
*
|
1993-12-07 |
1995-03-21 |
Genetics Institute, Inc. |
Mutants of bone morphogenetic proteins
|
US6027919A
(en)
*
|
1993-12-07 |
2000-02-22 |
Genetics Institute, Inc. |
BMP-12 and BMP-13 proteins and DNA encoding them
|
WO1995016035A2
(en)
*
|
1993-12-07 |
1995-06-15 |
Genetics Institute, Inc. |
Bmp-12, bmp-13 and tendon-inducing compositions thereof
|
US5906827A
(en)
*
|
1994-06-03 |
1999-05-25 |
Creative Biomolecules, Inc. |
Matrix for the manufacture of autogenous replacement body parts
|
US5846770A
(en)
*
|
1994-11-22 |
1998-12-08 |
Genetics Institute, Inc. |
DNA molecules encoding human chordin
|
US5645084A
(en)
*
|
1995-06-07 |
1997-07-08 |
Danek Medical, Inc. |
Method for spinal fusion without decortication
|
US5635372A
(en)
*
|
1995-05-18 |
1997-06-03 |
Genetics Institute, Inc. |
BMP-15 compositions
|
HU222664B1
(hu)
|
1995-06-05 |
2003-09-29 |
Genetics Institute, Llc |
Csont morfogenetikus protein (BMP) alkalmazása csont és ín vagy szalag funkcionális összeköttetésének regenerálására
|
US5902785A
(en)
*
|
1995-06-06 |
1999-05-11 |
Genetics Institute, Inc. |
Cartilage induction by bone morphogenetic proteins
|
EP0885308A4
(de)
*
|
1996-02-28 |
2002-02-27 |
Univ Vanderbilt |
Verbindungen und methoden zur herstellung embryonaler stammzellen
|
US5700774A
(en)
*
|
1996-03-26 |
1997-12-23 |
Genetics Institute, Inc. |
Compositions comprising bone morphogenic proteins and truncated parathyroid hormone related peptide, and methods of inducing cartilage by administration of same
|
US6498142B1
(en)
|
1996-05-06 |
2002-12-24 |
Curis, Inc. |
Morphogen treatment for chronic renal failure
|
US5965403A
(en)
*
|
1996-09-18 |
1999-10-12 |
Genetics Institute, Inc. |
Nucleic acids encoding bone morphogenic protein-16 (BMP-16)
|
DE69814352T3
(de)
|
1997-02-07 |
2009-08-13 |
Stryker Corp., Kalamazoo |
Matrixlose osteogene vorrichtungen und implantate und verfahren zu deren verwendung
|
US20010016646A1
(en)
|
1998-03-20 |
2001-08-23 |
David C. Rueger |
Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects
|
US7041641B2
(en)
|
1997-03-20 |
2006-05-09 |
Stryker Corporation |
Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
|
EP0980252B1
(de)
|
1997-05-05 |
2004-10-06 |
Curis, Inc. |
Therapien zur behandlung von akutem nierenversagen
|
EP0985149A1
(de)
|
1997-05-30 |
2000-03-15 |
Creative Biomolecules, Inc. |
Verfahren zur bestimmung der gewebemorphogenese und morphogenesische tätigkeit
|
US20020052026A1
(en)
|
1997-10-08 |
2002-05-02 |
Steven M. Vicik |
Methods of refolding proteins
|
US6027917A
(en)
|
1997-12-10 |
2000-02-22 |
Genetics Institute, Inc. |
Bone morphogenetic protein (BMP)-17 and BMP-18 compositions
|
US7147839B2
(en)
|
1998-05-29 |
2006-12-12 |
Curis, Inc. |
Methods for evaluating tissue morphogenesis and activity
|
US6849255B2
(en)
|
1998-08-18 |
2005-02-01 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Methods and compositions for enhancing cartilage repair
|
US7572440B2
(en)
|
1999-07-30 |
2009-08-11 |
Stryker Corporation |
Method for repairing a defect in an intervertebral disc
|
EP2374870B1
(de)
|
1998-10-06 |
2014-04-23 |
Stryker Corporation |
Zusammensetzung enthaltend ein osteogenes Protein ausgewählt aus OP-2, OP-3, BMP-2, BMP-3, BMP-4, BMP-5, BMP-6, BMP-9, BMP-10, BMP-11, BMP-15, BMP-3B, DPP, Vg-1, Vgr-1, 60A Protein, GDF-1, GDF-2, GDF-3, GDF-6, GDF-7, GDF-8, GDF-9, GDF-10 und GDF-11 zur Verwendung zur Wiederherstellung eines defekten Locus in einem Nicht-Gelenkknorpelgewebe
|
US6958149B2
(en)
|
1998-10-06 |
2005-10-25 |
Stryker Corporation |
Repair of larynx, trachea, and other fibrocartilaginous tissues
|
US6727224B1
(en)
|
1999-02-01 |
2004-04-27 |
Genetics Institute, Llc. |
Methods and compositions for healing and repair of articular cartilage
|
DE19906096A1
(de)
|
1999-02-13 |
2000-08-17 |
Walter Sebald |
Protein mit einem Heparin-bindenden Epitop
|
JP4703926B2
(ja)
|
1999-10-15 |
2011-06-15 |
ジェネティクス インスティテュート,エルエルシー |
骨形成蛋白をデリバリーするためのヒアルロン酸の処方
|
TW200526779A
(en)
|
2001-02-08 |
2005-08-16 |
Wyeth Corp |
Modified and stabilized GDF propeptides and uses thereof
|
TWI267378B
(en)
|
2001-06-08 |
2006-12-01 |
Wyeth Corp |
Calcium phosphate delivery vehicles for osteoinductive proteins
|
KR20050010778A
(ko)
|
2002-05-03 |
2005-01-28 |
밀레늄 바이올로직스 인코포레이티드 |
결합조직 자극 펩티드
|
EP1529061B1
(de)
|
2002-08-06 |
2008-02-13 |
Sanofi-Aventis Deutschland GmbH |
Verfahren zur isolierung eines intestilanen cholesterin bindenproteins
|
CA2504768A1
(en)
*
|
2002-11-14 |
2004-05-27 |
Adherex Technologies, Inc. |
Compounds and methods for modulating functions of classical cadherins
|
EP1675608B1
(de)
|
2003-09-12 |
2007-03-21 |
Wyeth |
Injizierbare feste calciumphosphat-stäbe zur abgabe von osteogenen proteinen
|
US7575751B2
(en)
|
2004-04-27 |
2009-08-18 |
Research Development Foundation |
Activin-A mutants
|
CA2567405A1
(en)
|
2004-05-25 |
2005-12-08 |
Stryker Corporation |
Use of morphogenic proteins for treating cartilage defects
|
US7473678B2
(en)
|
2004-10-14 |
2009-01-06 |
Biomimetic Therapeutics, Inc. |
Platelet-derived growth factor compositions and methods of use thereof
|
US8506646B2
(en)
|
2005-04-29 |
2013-08-13 |
Warsaw Orthopedic, Inc. |
Multi-purpose medical implant devices
|
US8147860B2
(en)
|
2005-12-06 |
2012-04-03 |
Etex Corporation |
Porous calcium phosphate bone material
|
WO2007092622A2
(en)
|
2006-02-09 |
2007-08-16 |
Biomimetic Therapeutics, Inc. |
Compositions and methods for treating bone
|
US9011930B2
(en)
|
2006-05-01 |
2015-04-21 |
Zycal Bioceuticals Healthcare Company, Inc. |
Nutritional supplement and use thereof
|
US20090298761A1
(en)
|
2006-05-17 |
2009-12-03 |
Donald Engelman |
Methods of treating cartilage defects using a soluble morphogenic protein complex
|
US9161967B2
(en)
|
2006-06-30 |
2015-10-20 |
Biomimetic Therapeutics, Llc |
Compositions and methods for treating the vertebral column
|
JP5484047B2
(ja)
|
2006-06-30 |
2014-05-07 |
バイオミメティック セラピューティクス, エルエルシー |
回旋筋腱板傷害を処置するためのpdgf−生体マトリックス組成物および方法
|
US8524265B2
(en)
|
2006-08-17 |
2013-09-03 |
Warsaw Orthopedic, Inc. |
Medical implant sheets useful for tissue regeneration
|
AU2007234612B2
(en)
|
2006-12-14 |
2013-06-27 |
Johnson & Johnson Regenerative Therapeutics, Llc |
Protein stabilization formulations
|
CA2674384C
(en)
*
|
2007-01-22 |
2016-11-15 |
Acologix, Inc. |
A peptide composition and a method of promoting cartilage formation
|
US7678764B2
(en)
|
2007-06-29 |
2010-03-16 |
Johnson & Johnson Regenerative Therapeutics, Llc |
Protein formulations for use at elevated temperatures
|
EP2187932B1
(de)
|
2007-08-07 |
2015-01-28 |
DePuy Synthes Products, LLC |
Proteinformulierungen mit gdf-5 in wässriger saurer lösung
|
CA2720845A1
(en)
|
2008-04-14 |
2009-10-22 |
Advanced Technologies And Regenerative Medicine, Llc |
Liquid buffered gdf-5 formulations
|
BRPI0918611B8
(pt)
|
2008-09-09 |
2021-06-22 |
Biomimetic Therapeutics Inc |
composição que compreende uma matriz biocompatível e um fator de crescimento derivado de plaqueta e kit
|
US8609127B2
(en)
|
2009-04-03 |
2013-12-17 |
Warsaw Orthopedic, Inc. |
Medical implant with bioactive material and method of making the medical implant
|
WO2010144696A1
(en)
|
2009-06-11 |
2010-12-16 |
Burnham Institute For Medical Research |
Directed differentiation of stem cells
|
CN107080834A
(zh)
|
2010-02-22 |
2017-08-22 |
生物模拟治疗有限责任公司 |
用于治疗腱病的血小板衍生生长因子组合物和方法
|
US10034945B2
(en)
|
2012-07-13 |
2018-07-31 |
Trustees Of Tufts College |
Silk powder compaction for production of constructs with high mechanical strength and stiffness
|
JP2016204292A
(ja)
*
|
2015-04-21 |
2016-12-08 |
国立大学法人 熊本大学 |
Bmp7変異体とアルブミンとの融合体、及び該融合体を含む腎疾患治療剤
|
US11578110B2
(en)
|
2015-08-25 |
2023-02-14 |
Histide Ag |
Compounds for inducing tissue formation and uses thereof
|
EP3349777A2
(de)
*
|
2015-09-17 |
2018-07-25 |
Histide AG |
Pharmazeutische assoziation mit einem an einen bioaktiven träger konjugierten wachstumsfaktorrezeptoragonisten zur umwandlung einer neoplastischen zelle in eine nicht-neoplastische zelle und deren verwendungen
|
US10780171B2
(en)
|
2015-10-26 |
2020-09-22 |
President And Fellows Of Harvard College |
Reduced and oxidized polysaccharides and methods of use thereof
|