ATE20829T1 - Vorsaeule zum vorkonzentrieren von durch chromatographie zu trennenden stoffen, sowie vorrichtung fuer ein fluessigkeitschromatographiesystem und kupplungsstueck fuer diese vorrichtung. - Google Patents

Vorsaeule zum vorkonzentrieren von durch chromatographie zu trennenden stoffen, sowie vorrichtung fuer ein fluessigkeitschromatographiesystem und kupplungsstueck fuer diese vorrichtung.

Info

Publication number
ATE20829T1
ATE20829T1 AT83200476T AT83200476T ATE20829T1 AT E20829 T1 ATE20829 T1 AT E20829T1 AT 83200476 T AT83200476 T AT 83200476T AT 83200476 T AT83200476 T AT 83200476T AT E20829 T1 ATE20829 T1 AT E20829T1
Authority
AT
Austria
Prior art keywords
substances
column
separated
liquid chromatography
coupling piece
Prior art date
Application number
AT83200476T
Other languages
English (en)
Inventor
Henri M Ruijten
Bree Hans De
Amsterdam Peter H Van
Elbert Wiegers
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar Int Res filed Critical Duphar Int Res
Application granted granted Critical
Publication of ATE20829T1 publication Critical patent/ATE20829T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/12—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the preparation of the feed
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/08—Preparation using an enricher
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/08—Preparation using an enricher
    • G01N2030/085—Preparation using an enricher using absorbing precolumn
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6017—Fluid distributors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G01N30/6065—Construction of the column body with varying cross section

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT83200476T 1982-04-28 1983-04-01 Vorsaeule zum vorkonzentrieren von durch chromatographie zu trennenden stoffen, sowie vorrichtung fuer ein fluessigkeitschromatographiesystem und kupplungsstueck fuer diese vorrichtung. ATE20829T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8201757 1982-04-28
EP83200476A EP0092860B1 (de) 1982-04-28 1983-04-01 Vorsäule zum Vorkonzentrieren von durch Chromatographie zu trennenden Stoffen, sowie Vorrichtung für ein Flüssigkeitschromatographiesystem und Kupplungsstück für diese Vorrichtung

Publications (1)

Publication Number Publication Date
ATE20829T1 true ATE20829T1 (de) 1986-08-15

Family

ID=19839666

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83200476T ATE20829T1 (de) 1982-04-28 1983-04-01 Vorsaeule zum vorkonzentrieren von durch chromatographie zu trennenden stoffen, sowie vorrichtung fuer ein fluessigkeitschromatographiesystem und kupplungsstueck fuer diese vorrichtung.

Country Status (12)

Country Link
US (1) US4554071A (de)
EP (1) EP0092860B1 (de)
JP (1) JPS58196455A (de)
KR (1) KR900008957B1 (de)
AT (1) ATE20829T1 (de)
AU (1) AU558353B2 (de)
CA (2) CA1205751A (de)
DE (1) DE3364639D1 (de)
DK (1) DK163801C (de)
ES (2) ES279037Y (de)
IL (1) IL68480A0 (de)
ZA (1) ZA832902B (de)

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DE3606474A1 (de) * 1986-02-28 1987-09-17 Merck Patent Gmbh Chromatographievorsaeule
JPS6332368A (ja) * 1986-07-25 1988-02-12 Tosoh Corp 高密度充填型の濾過装置
JP2766869B2 (ja) * 1988-03-09 1998-06-18 扶桑薬品工業株式会社 体液材料中の低級カルボン酸の定量法
JP2625001B2 (ja) * 1988-06-23 1997-06-25 明文 山田 塩化物イオン置換カラム及びこれを用いたフローインジェクション分析装置
DE3842315A1 (de) * 1988-12-16 1990-06-21 Bodenseewerk Perkin Elmer Co Anordnung zur anreicherung von probensubstanz fuer spektroskopische zwecke
US5246577A (en) * 1990-05-29 1993-09-21 Millipore Corporation Apparatus for effecting capillary electrophoresis
DE4110730A1 (de) * 1991-04-03 1992-10-15 Fresenius Ag Vorrichtung zur auftrennung von zumindest zwei biologischen stoffen in loesung durch adsorption
US5338448A (en) * 1992-10-16 1994-08-16 Sarasep, Inc. Method of preventing contamination of a chromatography column
JPH07198701A (ja) * 1993-11-26 1995-08-01 Ngk Insulators Ltd 低圧高速液体クロマトグラフィー用カラム、低圧高速液体クロマトグラフィー用カラム装置及び同カラム装置の使用方法
US5462660A (en) * 1994-04-22 1995-10-31 The United States Of America As Represented By The Secretary Of Agriculture High performance liquid chromatography injection system for the simultaneous concentration and analysis of trace components
EP0686848A1 (de) * 1994-05-09 1995-12-13 Shiseido Company Limited Flüssigchromatograph mit Mikro- oder Halbmikrokolonne
ES2103224B1 (es) * 1994-05-18 1998-04-16 Univ Cordoba Analizador automatico para el tratamiento previo de muestras liquidas.
US6177008B1 (en) * 1996-08-01 2001-01-23 Merck & Co., Inc. Dual compartment solid phase extraction cartridge
JP3729738B2 (ja) * 1998-09-18 2005-12-21 エーザイ株式会社 試料中の成分濃縮用カラム
US6309541B1 (en) 1999-10-29 2001-10-30 Ontogen Corporation Apparatus and method for multiple channel high throughput purification
US6458273B1 (en) 1999-10-29 2002-10-01 Ontogen Corporation Sample separation apparatus and method for multiple channel high throughput purification
US20020008058A1 (en) * 1999-06-03 2002-01-24 Kerry D. Nugent Tapered bore column for high performance liquid chromatography
US6358414B1 (en) 1999-10-29 2002-03-19 Ontogen Corporation Pressure regulation apparatus and method for multiple channel high throughput purification
US6355164B1 (en) 1999-10-29 2002-03-12 Ontogen Corporation Sample collection apparatus and method for multiple channel high throughput purification
US6723236B2 (en) * 2002-03-19 2004-04-20 Waters Investments Limited Device for solid phase extraction and method for purifying samples prior to analysis
JP2006153850A (ja) * 2004-08-31 2006-06-15 Showa Denko Kk 化合物精製濃縮用具及びそれを用いた化合物の精製濃縮方法
DE102006028126A1 (de) * 2006-06-15 2007-12-20 Sls Micro Technology Gmbh Miniaturisierte gaschromatographische Analysevorrichtung mit Probenanreicherung
US9005417B1 (en) * 2008-10-01 2015-04-14 Sandia Corporation Devices, systems, and methods for microscale isoelectric fractionation
US8962346B2 (en) 2010-07-08 2015-02-24 Sandia Corporation Devices, systems, and methods for conducting assays with improved sensitivity using sedimentation
US8945914B1 (en) 2010-07-08 2015-02-03 Sandia Corporation Devices, systems, and methods for conducting sandwich assays using sedimentation
US9795961B1 (en) 2010-07-08 2017-10-24 National Technology & Engineering Solutions Of Sandia, Llc Devices, systems, and methods for detecting nucleic acids using sedimentation
WO2012118982A2 (en) 2011-03-02 2012-09-07 Sandia Corporation Axial flow heat exchanger devices and methods for heat transfer using axial flow devices
BR112013030965A2 (pt) * 2011-06-03 2016-11-29 Dow Global Technologies Llc aparelho para cromatografia de polímeros e método para cromatografia de polímeros
US9244065B1 (en) 2012-03-16 2016-01-26 Sandia Corporation Systems, devices, and methods for agglutination assays using sedimentation
US9803238B1 (en) 2013-11-26 2017-10-31 National Technology & Engineering Solutions Of Sandia, Llc Method and apparatus for purifying nucleic acids and performing polymerase chain reaction assays using an immiscible fluid
US9702871B1 (en) 2014-11-18 2017-07-11 National Technology & Engineering Solutions Of Sandia, Llc System and method for detecting components of a mixture including a valving scheme for competition assays
US10254298B1 (en) 2015-03-25 2019-04-09 National Technology & Engineering Solutions Of Sandia, Llc Detection of metabolites for controlled substances
US9804133B1 (en) * 2015-08-27 2017-10-31 Mark A. Stone Method to enable the use of larger injection volumes and to reduce extra-column effects in chromatographic separations
US10786755B2 (en) * 2015-08-27 2020-09-29 Mark A. Stone Low-retention pre-columns: a straightforward approach to enable larger injection volumes and reduce extra-column effects in HPLC
US10406528B1 (en) 2016-08-04 2019-09-10 National Technology & Engineering Solutions Of Sandia, Llc Non-contact temperature control system for microfluidic devices
US10981174B1 (en) 2016-08-04 2021-04-20 National Technology & Engineering Solutions Of Sandia, Llc Protein and nucleic acid detection for microfluidic devices
US10786811B1 (en) 2016-10-24 2020-09-29 National Technology & Engineering Solutions Of Sandia, Llc Detection of active and latent infections with microfluidic devices and systems thereof
WO2018110177A1 (ja) * 2016-12-13 2018-06-21 オルガノ株式会社 イオン交換体充填カートリッジ及び金属除去カラム

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US3578785A (en) * 1968-02-12 1971-05-18 Sondell Research & Dev Co Outlet plug and conduit for chromatograph
US3782078A (en) * 1972-02-14 1974-01-01 J Jerpe Apparatus for chromatographic separations
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JPS5233595A (en) * 1975-09-09 1977-03-14 Kusano Kagaku Kikai Seisakusho:Kk Pressure resistant column for liquid column chromatography
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FR2491215A1 (fr) * 1980-09-26 1982-04-02 Prolabo Sa Dispositif pour associer une precolonne et une colonne en chromatographie, emploi dudit dispositif pour la realisation d'un chromatographe automatique industriel

Also Published As

Publication number Publication date
AU1388983A (en) 1983-11-03
KR840004577A (ko) 1984-10-22
JPH0546499B2 (de) 1993-07-14
DK182383D0 (da) 1983-04-25
DK163801B (da) 1992-04-06
ES279037U (es) 1984-12-01
ES279037Y (es) 1985-06-01
EP0092860B1 (de) 1986-07-23
DE3364639D1 (en) 1986-08-28
IL68480A0 (en) 1983-07-31
ZA832902B (en) 1984-01-25
ES8402165A1 (es) 1984-01-16
EP0092860A1 (de) 1983-11-02
DK163801C (da) 1992-09-07
DK182383A (da) 1983-10-29
AU558353B2 (en) 1987-01-29
JPS58196455A (ja) 1983-11-15
KR900008957B1 (ko) 1990-12-15
ES521816A0 (es) 1984-01-16
CA1203224A (en) 1986-04-15
CA1205751A (en) 1986-06-10
US4554071A (en) 1985-11-19

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee