ATE145201T1 - Dihydro-isoquinolinderivate - Google Patents

Dihydro-isoquinolinderivate

Info

Publication number
ATE145201T1
ATE145201T1 AT91810954T AT91810954T ATE145201T1 AT E145201 T1 ATE145201 T1 AT E145201T1 AT 91810954 T AT91810954 T AT 91810954T AT 91810954 T AT91810954 T AT 91810954T AT E145201 T1 ATE145201 T1 AT E145201T1
Authority
AT
Austria
Prior art keywords
dihydro
isoquinoline derivatives
4alkoxy
acid addition
addition salts
Prior art date
Application number
AT91810954T
Other languages
English (en)
Inventor
Reto Naef
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Application granted granted Critical
Publication of ATE145201T1 publication Critical patent/ATE145201T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT91810954T 1990-12-13 1991-12-09 Dihydro-isoquinolinderivate ATE145201T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909027055A GB9027055D0 (en) 1990-12-13 1990-12-13 Organic compounds

Publications (1)

Publication Number Publication Date
ATE145201T1 true ATE145201T1 (de) 1996-11-15

Family

ID=10686945

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91810954T ATE145201T1 (de) 1990-12-13 1991-12-09 Dihydro-isoquinolinderivate

Country Status (25)

Country Link
US (1) US5177085A (de)
EP (1) EP0490823B1 (de)
JP (1) JPH0764820B2 (de)
KR (1) KR920012040A (de)
AT (1) ATE145201T1 (de)
AU (1) AU643575B2 (de)
CA (1) CA2057524A1 (de)
CZ (1) CZ281669B6 (de)
DE (1) DE69123124T2 (de)
DK (1) DK0490823T3 (de)
ES (1) ES2093694T3 (de)
FI (1) FI915844A (de)
GB (1) GB9027055D0 (de)
GR (1) GR3022034T3 (de)
HU (1) HUT61729A (de)
IE (1) IE914325A1 (de)
IL (1) IL100328A (de)
MX (1) MX9102502A (de)
MY (1) MY129941A (de)
NZ (1) NZ240936A (de)
PL (1) PL168329B1 (de)
PT (1) PT99775B (de)
RU (1) RU2060992C1 (de)
TW (1) TW201736B (de)
ZA (1) ZA919858B (de)

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US5786354A (en) * 1994-06-21 1998-07-28 Celltech Therapeutics, Limited Tri-substituted phenyl derivatives and processes for their preparation
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US5948820A (en) 1994-08-22 1999-09-07 Yoshitomi Pharmaceutical Industries, Ltd. Benzene compound and pharmaceutical use thereof
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IT1296985B1 (it) 1997-12-19 1999-08-03 Zambon Spa Derivati benzazinici inibitori della fosfodiesterasi 4
IT1302677B1 (it) 1998-10-15 2000-09-29 Zambon Spa Derivati benzazinici inibitori della fosfodiesterasi 4
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WO2002096888A1 (de) * 2001-05-29 2002-12-05 Schering Aktiengesellschaft Cdk inhibitorische pyrimidine, deren herstellung und verwendung als arzneimittel
PL211954B1 (pl) * 2002-01-11 2012-07-31 Sankyo Co Związek, kompozycja farmaceutyczna oraz zastosowanie kompozycji farmaceutycznej
US7745180B2 (en) * 2002-04-24 2010-06-29 Hitachi Chemical Co., Ltd. Device and method for high-throughput quantification of mRNA from whole blood
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US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
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HU196758B (en) * 1986-05-21 1989-01-30 Gyogyszerkutato Intezet Process for production of 3-hidroxi-methil-quinolines and medical compositions containing them
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GB8800397D0 (en) * 1988-01-08 1988-02-10 Sandoz Ltd Improvements in/relating to organic compounds

Also Published As

Publication number Publication date
HUT61729A (en) 1993-03-01
HU913760D0 (en) 1992-02-28
GB9027055D0 (en) 1991-02-06
KR920012040A (ko) 1992-07-25
ES2093694T3 (es) 1997-01-01
PT99775A (pt) 1992-11-30
DK0490823T3 (de) 1997-02-17
PL168329B1 (pl) 1996-02-29
CZ281669B6 (cs) 1996-12-11
JPH0764820B2 (ja) 1995-07-12
IL100328A (en) 1995-12-08
IL100328A0 (en) 1992-09-06
EP0490823B1 (de) 1996-11-13
NZ240936A (en) 1993-09-27
US5177085A (en) 1993-01-05
RU2060992C1 (ru) 1996-05-27
PT99775B (pt) 1999-05-31
DE69123124D1 (de) 1996-12-19
IE914325A1 (en) 1992-06-17
TW201736B (de) 1993-03-11
AU643575B2 (en) 1993-11-18
FI915844A (fi) 1992-06-14
MX9102502A (es) 1992-06-01
EP0490823A1 (de) 1992-06-17
JPH04275276A (ja) 1992-09-30
CA2057524A1 (en) 1992-06-14
PL292738A1 (en) 1992-12-14
AU8898591A (en) 1992-06-18
CS375791A3 (en) 1992-06-17
DE69123124T2 (de) 1997-05-15
GR3022034T3 (en) 1997-03-31
MY129941A (en) 2007-05-31
FI915844A0 (fi) 1991-12-11
ZA919858B (en) 1993-06-14

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEFA Change of the company name
REN Ceased due to non-payment of the annual fee