ATE132504T1 - Immunotestreagenzien und verfahren zur bestimmung von cyclosporin - Google Patents

Immunotestreagenzien und verfahren zur bestimmung von cyclosporin

Info

Publication number
ATE132504T1
ATE132504T1 AT91113328T AT91113328T ATE132504T1 AT E132504 T1 ATE132504 T1 AT E132504T1 AT 91113328 T AT91113328 T AT 91113328T AT 91113328 T AT91113328 T AT 91113328T AT E132504 T1 ATE132504 T1 AT E132504T1
Authority
AT
Austria
Prior art keywords
cyclosporine
cyclosporin
determining
test reagents
amino acid
Prior art date
Application number
AT91113328T
Other languages
English (en)
Inventor
Marjorie A Morrison
Victoria P Meucci
Steven E Lunetta
Mariola B Zajac
Elizabeth A Simpson
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE132504T1 publication Critical patent/ATE132504T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT91113328T 1990-08-15 1991-08-08 Immunotestreagenzien und verfahren zur bestimmung von cyclosporin ATE132504T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56784290A 1990-08-15 1990-08-15

Publications (1)

Publication Number Publication Date
ATE132504T1 true ATE132504T1 (de) 1996-01-15

Family

ID=24268868

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91113328T ATE132504T1 (de) 1990-08-15 1991-08-08 Immunotestreagenzien und verfahren zur bestimmung von cyclosporin

Country Status (10)

Country Link
US (2) US5489668A (de)
EP (1) EP0473961B1 (de)
JP (1) JP3171460B2 (de)
AT (1) ATE132504T1 (de)
AU (1) AU642035B2 (de)
CA (1) CA2049089C (de)
DE (1) DE69116034T2 (de)
DK (1) DK0473961T3 (de)
ES (1) ES2084069T3 (de)
GR (1) GR3019512T3 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69133095T2 (de) * 1990-11-20 2003-03-27 Dade Behring Marburg Gmbh Cyclosporin-Immunoassay
EP0649533B1 (de) * 1992-03-30 2000-05-10 Abbott Laboratories Reagenzien und verfahren zum nachweis und zur quantifizierung von thyroxin in flüssigen proben
US5352803A (en) * 1992-03-30 1994-10-04 Abbott Laboratories 5(6)-methyl substituted fluorescein derivatives
GB9307491D0 (en) * 1993-04-08 1993-06-02 Sandoz Ltd Organic compounds
USRE40596E1 (en) * 1993-04-08 2008-12-02 Novartis Ag Rapamycin assay
DE69430060T2 (de) 1993-04-23 2002-11-07 Abbott Lab Antikörper von rapamycinen mit offenem ring
US5504091A (en) * 1993-04-23 1996-04-02 American Home Products Corporation Biotin esters of rapamycin
US7279561B1 (en) 1993-04-23 2007-10-09 Wyeth Anti-rapamycin monoclonal antibodies
US5393891A (en) * 1993-06-08 1995-02-28 The Du Pont Merck Pharmaceutical Company Immunoassay reagents and methods for detecting brequinar and analogs
US5650288A (en) * 1995-07-14 1997-07-22 Macfarlane; Gordon D. Immunophilin-bound immunosuppressant assay
US20030220234A1 (en) * 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
EP0991660B8 (de) 1997-10-08 2006-04-05 Isotechnika,Inc. DEUTERIERtE und undeuterierte CYCLOSPORIN-ANALOGA UND IHRE VERWENDUNG ALS IMMUNMODULIERENDE AGENtIEN
US5990274A (en) * 1997-11-25 1999-11-23 Dade Behring Inc. Cyclosporine derivatives and uses thereof
US6972339B2 (en) * 2001-09-07 2005-12-06 Epoch Biosciences, Inc. Compounds and methods for fluorescent labeling
US8569516B2 (en) 2001-09-07 2013-10-29 Elitech Holding B.V. Compounds and methods for fluorescent labeling
PT1436321E (pt) 2001-10-19 2006-10-31 Isotechnika Inc Sintese de analogos de ciclosporina
KR100444698B1 (ko) * 2001-11-08 2004-08-21 한국과학기술연구원 면역복합체 단일검출시약, 그의 제조방법 및 그를 이용한농약의 검출방법
US8022188B2 (en) * 2006-04-24 2011-09-20 Abbott Laboratories Immunosuppressant binding antibodies and methods of obtaining and using same
US7883855B2 (en) * 2006-07-21 2011-02-08 Abbott Laboratories Immunosuppressant drug extraction reagent for immunoassays
US7576057B2 (en) 2006-11-20 2009-08-18 Scynexis, Inc. Cyclic peptides
JP5319549B2 (ja) 2006-12-29 2013-10-16 アボット・ラボラトリーズ 溶液内捕捉イムノアッセイで使用する非変性細胞溶解試薬
EP2118654B1 (de) * 2006-12-29 2013-03-27 Abbott Laboratories Diagnostischer test zum nachweis eines moleküls oder arzneistoffs in vollblut
CA2673296C (en) 2006-12-29 2012-10-16 Abbott Laboratories Improved assay for immunosuppressant drugs
US7914999B2 (en) * 2006-12-29 2011-03-29 Abbott Laboratories Non-denaturing lysis reagent
ES2377167T3 (es) 2007-05-24 2012-03-23 Abbott Laboratories Inmunoensayos que muestran reactividad cruzada reducida con metabolitos de analito de fármacos hidrófobos
ES2559311T3 (es) * 2007-12-19 2016-02-11 Abbott Laboratories Reactivo de extracción de fármacos inmunosupresores para inmunoanálisis
US20090170218A1 (en) * 2008-01-02 2009-07-02 Dade Behring Inc. Methods for detection of cyclosporin a
CN110320364B (zh) * 2018-03-30 2023-03-31 洛阳普泰生物技术有限公司 一种双抗夹心胶体金检测试剂盒、及其制备方法与应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1023287A (en) * 1972-12-08 1977-12-27 Boehringer Mannheim G.M.B.H. Process for the preparation of carrier-bound proteins
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
DE2819094A1 (de) * 1977-05-10 1978-11-23 Sandoz Ag Cyclosporin-derivate, ihre verwendung und herstellung
ATE92501T1 (de) * 1984-10-04 1993-08-15 Sandoz Ag Monoklonale antikoerper gegen zyklosporine.
US5169773A (en) * 1984-10-04 1992-12-08 Sandoz Ltd. Monoclonal antibodies to cyclosporins
US4727035A (en) * 1984-11-14 1988-02-23 Mahoney Walter C Immunoassay for cyclosporin
US5124457A (en) * 1986-05-21 1992-06-23 Abbott Laboratories Phencyclidine and phencyclidine metabolites assay, tracers, immunogens and antibodies
US4939264A (en) * 1986-07-14 1990-07-03 Abbott Laboratories Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies
US5239057A (en) * 1987-03-27 1993-08-24 Abbott Laboratories Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies
EP0283801A3 (de) * 1987-03-27 1990-05-30 Abbott Laboratories Fluoreszenz-Polarisations-Test für Cyclosporin A und Metaboliten und verwandte Immunogene und Antikörper
US5427960A (en) * 1987-03-27 1995-06-27 Abbott Laboratories Fluorescence polarization assay for cyclosporin A and metabolites and related immunogens and antibodies
EP0329184A3 (de) * 1988-02-19 1990-05-23 Neorx Corporation Antimere und antimere Konjugation

Also Published As

Publication number Publication date
GR3019512T3 (en) 1996-07-31
EP0473961A3 (en) 1993-04-14
DE69116034T2 (de) 1996-06-20
US5750413A (en) 1998-05-12
CA2049089C (en) 2002-09-03
ES2084069T3 (es) 1996-05-01
AU642035B2 (en) 1993-10-07
US5489668A (en) 1996-02-06
JPH04253999A (ja) 1992-09-09
DK0473961T3 (da) 1996-07-01
CA2049089A1 (en) 1992-02-16
AU8247191A (en) 1992-02-20
EP0473961A2 (de) 1992-03-11
EP0473961B1 (de) 1996-01-03
DE69116034D1 (de) 1996-02-15
JP3171460B2 (ja) 2001-05-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee