ATE102610T1 - Imidazolderivate, verfahren zu deren herstellung und diese enthaltende antiulkusmittel. - Google Patents

Imidazolderivate, verfahren zu deren herstellung und diese enthaltende antiulkusmittel.

Info

Publication number
ATE102610T1
ATE102610T1 AT90115236T AT90115236T ATE102610T1 AT E102610 T1 ATE102610 T1 AT E102610T1 AT 90115236 T AT90115236 T AT 90115236T AT 90115236 T AT90115236 T AT 90115236T AT E102610 T1 ATE102610 T1 AT E102610T1
Authority
AT
Austria
Prior art keywords
carbon atoms
antiulcic
preparation
alkyl group
agents containing
Prior art date
Application number
AT90115236T
Other languages
English (en)
Inventor
Susumu - Shingoryouguchi Okabe
Mitsuo Masaki
Tomio Yamakawa
Hitoshi Matsukura
Yustaka Nomura
Original Assignee
Nippon Chemiphar Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co filed Critical Nippon Chemiphar Co
Application granted granted Critical
Publication of ATE102610T1 publication Critical patent/ATE102610T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16C—SHAFTS; FLEXIBLE SHAFTS; ELEMENTS OR CRANKSHAFT MECHANISMS; ROTARY BODIES OTHER THAN GEARING ELEMENTS; BEARINGS
    • F16C33/00—Parts of bearings; Special methods for making bearings or parts thereof
    • F16C33/72—Sealings
    • F16C33/76—Sealings of ball or roller bearings
    • F16C33/78—Sealings of ball or roller bearings with a diaphragm, disc, or ring, with or without resilient members
    • F16C33/7816—Details of the sealing or parts thereof, e.g. geometry, material
    • F16C33/782—Details of the sealing or parts thereof, e.g. geometry, material of the sealing region
    • F16C33/7823—Details of the sealing or parts thereof, e.g. geometry, material of the sealing region of sealing lips
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16C—SHAFTS; FLEXIBLE SHAFTS; ELEMENTS OR CRANKSHAFT MECHANISMS; ROTARY BODIES OTHER THAN GEARING ELEMENTS; BEARINGS
    • F16C33/00—Parts of bearings; Special methods for making bearings or parts thereof
    • F16C33/72—Sealings
    • F16C33/76—Sealings of ball or roller bearings
    • F16C33/78—Sealings of ball or roller bearings with a diaphragm, disc, or ring, with or without resilient members
    • F16C33/784—Sealings of ball or roller bearings with a diaphragm, disc, or ring, with or without resilient members mounted to a groove in the inner surface of the outer race and extending toward the inner race
    • F16C33/7843—Sealings of ball or roller bearings with a diaphragm, disc, or ring, with or without resilient members mounted to a groove in the inner surface of the outer race and extending toward the inner race with a single annular sealing disc
    • F16C33/7853—Sealings of ball or roller bearings with a diaphragm, disc, or ring, with or without resilient members mounted to a groove in the inner surface of the outer race and extending toward the inner race with a single annular sealing disc with one or more sealing lips to contact the inner race
    • F16C33/7856—Sealings of ball or roller bearings with a diaphragm, disc, or ring, with or without resilient members mounted to a groove in the inner surface of the outer race and extending toward the inner race with a single annular sealing disc with one or more sealing lips to contact the inner race with a single sealing lip
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16C—SHAFTS; FLEXIBLE SHAFTS; ELEMENTS OR CRANKSHAFT MECHANISMS; ROTARY BODIES OTHER THAN GEARING ELEMENTS; BEARINGS
    • F16C33/00—Parts of bearings; Special methods for making bearings or parts thereof
    • F16C33/72—Sealings
    • F16C33/76—Sealings of ball or roller bearings
    • F16C33/78—Sealings of ball or roller bearings with a diaphragm, disc, or ring, with or without resilient members
    • F16C33/7869—Sealings of ball or roller bearings with a diaphragm, disc, or ring, with or without resilient members mounted with a cylindrical portion to the inner surface of the outer race and having a radial portion extending inward
    • F16C33/7873—Sealings of ball or roller bearings with a diaphragm, disc, or ring, with or without resilient members mounted with a cylindrical portion to the inner surface of the outer race and having a radial portion extending inward with a single sealing ring of generally L-shaped cross-section
    • F16C33/7876—Sealings of ball or roller bearings with a diaphragm, disc, or ring, with or without resilient members mounted with a cylindrical portion to the inner surface of the outer race and having a radial portion extending inward with a single sealing ring of generally L-shaped cross-section with sealing lips
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16J—PISTONS; CYLINDERS; SEALINGS
    • F16J15/00—Sealings
    • F16J15/16—Sealings between relatively-moving surfaces
    • F16J15/32—Sealings between relatively-moving surfaces with elastic sealings, e.g. O-rings
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16J—PISTONS; CYLINDERS; SEALINGS
    • F16J15/00—Sealings
    • F16J15/16—Sealings between relatively-moving surfaces
    • F16J15/32—Sealings between relatively-moving surfaces with elastic sealings, e.g. O-rings
    • F16J15/3204—Sealings between relatively-moving surfaces with elastic sealings, e.g. O-rings with at least one lip
    • F16J15/322—Sealings between relatively-moving surfaces with elastic sealings, e.g. O-rings with at least one lip supported in a direction perpendicular to the surfaces
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16J—PISTONS; CYLINDERS; SEALINGS
    • F16J15/00—Sealings
    • F16J15/16—Sealings between relatively-moving surfaces
    • F16J15/32—Sealings between relatively-moving surfaces with elastic sealings, e.g. O-rings
    • F16J15/3268—Mounting of sealing rings
    • F16J15/3276—Mounting of sealing rings with additional static sealing between the sealing, or its casing or support, and the surface on which it is mounted
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16C—SHAFTS; FLEXIBLE SHAFTS; ELEMENTS OR CRANKSHAFT MECHANISMS; ROTARY BODIES OTHER THAN GEARING ELEMENTS; BEARINGS
    • F16C19/00—Bearings with rolling contact, for exclusively rotary movement
    • F16C19/22—Bearings with rolling contact, for exclusively rotary movement with bearing rollers essentially of the same size in one or more circular rows, e.g. needle bearings
    • F16C19/24—Bearings with rolling contact, for exclusively rotary movement with bearing rollers essentially of the same size in one or more circular rows, e.g. needle bearings for radial load mainly
    • F16C19/26—Bearings with rolling contact, for exclusively rotary movement with bearing rollers essentially of the same size in one or more circular rows, e.g. needle bearings for radial load mainly with a single row of rollers
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16C—SHAFTS; FLEXIBLE SHAFTS; ELEMENTS OR CRANKSHAFT MECHANISMS; ROTARY BODIES OTHER THAN GEARING ELEMENTS; BEARINGS
    • F16C2361/00—Apparatus or articles in engineering in general
    • F16C2361/61—Toothed gear systems, e.g. support of pinion shafts
AT90115236T 1989-08-10 1990-08-08 Imidazolderivate, verfahren zu deren herstellung und diese enthaltende antiulkusmittel. ATE102610T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP20919289 1989-08-10

Publications (1)

Publication Number Publication Date
ATE102610T1 true ATE102610T1 (de) 1994-03-15

Family

ID=16568877

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90115236T ATE102610T1 (de) 1989-08-10 1990-08-08 Imidazolderivate, verfahren zu deren herstellung und diese enthaltende antiulkusmittel.

Country Status (18)

Country Link
US (1) US5091403A (de)
EP (1) EP0412529B1 (de)
JP (1) JP2794640B2 (de)
KR (1) KR960011377B1 (de)
AT (1) ATE102610T1 (de)
AU (1) AU630839B2 (de)
CA (1) CA2022903A1 (de)
DD (1) DD297159A5 (de)
DE (1) DE69007203T2 (de)
DK (1) DK0412529T3 (de)
ES (1) ES2062223T3 (de)
FI (1) FI903967A0 (de)
HU (1) HU206686B (de)
MX (1) MX171158B (de)
NO (1) NO179004C (de)
PL (1) PL163654B1 (de)
RU (2) RU2026293C1 (de)
ZA (1) ZA906247B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2614756B2 (ja) * 1988-08-10 1997-05-28 日本ケミファ株式会社 イミダゾール誘導体およびその製造法ならびにこれを含有する抗潰瘍剤
JPH0770083A (ja) * 1993-07-05 1995-03-14 Nippon Chemiphar Co Ltd イミダゾール誘導体を有効成分とする血圧降下剤
JP3046924B2 (ja) * 1995-03-27 2000-05-29 株式会社アラクス イミダゾリン誘導体又はそれらの可能な互変異性体及びそれらの製造方法並びにそれらを有効成分とする創傷治療薬
JP6086865B2 (ja) 2011-08-03 2017-03-01 協和発酵キリン株式会社 ジベンゾオキセピン誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0251536A1 (de) * 1986-06-24 1988-01-07 FISONS plc Benzimidazole, ihre Herstellung, Formulierung und Verwendung als Magensäuresekretionshemmer
IT1222412B (it) * 1987-07-31 1990-09-05 Chiesi Farma Spa Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono
JP2614756B2 (ja) * 1988-08-10 1997-05-28 日本ケミファ株式会社 イミダゾール誘導体およびその製造法ならびにこれを含有する抗潰瘍剤

Also Published As

Publication number Publication date
PL286432A1 (en) 1991-04-22
DE69007203T2 (de) 1994-07-28
DE69007203D1 (de) 1994-04-14
MX171158B (de) 1993-10-05
NO903514D0 (no) 1990-08-09
JP2794640B2 (ja) 1998-09-10
ES2062223T3 (es) 1994-12-16
KR960011377B1 (ko) 1996-08-22
PL163654B1 (pl) 1994-04-29
HU206686B (en) 1992-12-28
NO179004B (no) 1996-04-09
NO179004C (no) 1996-07-17
EP0412529B1 (de) 1994-03-09
FI903967A0 (fi) 1990-08-10
NO903514L (no) 1991-02-11
RU2069212C1 (ru) 1996-11-20
AU6085190A (en) 1991-02-14
HUT54663A (en) 1991-03-28
EP0412529A1 (de) 1991-02-13
DK0412529T3 (da) 1994-04-05
DD297159A5 (de) 1992-01-02
JPH03163065A (ja) 1991-07-15
CA2022903A1 (en) 1991-02-11
ZA906247B (en) 1991-06-26
US5091403A (en) 1992-02-25
AU630839B2 (en) 1992-11-05
KR910004573A (ko) 1991-03-28
HU904946D0 (en) 1991-01-28
RU2026293C1 (ru) 1995-01-09

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee