ATA900788A - Virushältiger impfstoff, rekombinantes virus und verfahren zum exprimieren eines genproduktes - Google Patents
Virushältiger impfstoff, rekombinantes virus und verfahren zum exprimieren eines genproduktesInfo
- Publication number
- ATA900788A ATA900788A AT0900788A AT900788A ATA900788A AT A900788 A ATA900788 A AT A900788A AT 0900788 A AT0900788 A AT 0900788A AT 900788 A AT900788 A AT 900788A AT A900788 A ATA900788 A AT A900788A
- Authority
- AT
- Austria
- Prior art keywords
- virus
- expressing
- gene product
- containing vaccine
- recombinant virus
- Prior art date
Links
- 108010008038 Synthetic Vaccines Proteins 0.000 title 1
- 241000700605 Viruses Species 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24041—Use of virus, viral particle or viral elements as a vector
- C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
- C12N2760/18122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/20011—Coronaviridae
- C12N2770/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9071187A | 1987-08-28 | 1987-08-28 | |
US11033587A | 1987-10-20 | 1987-10-20 | |
US18605488A | 1988-04-25 | 1988-04-25 | |
US23439088A | 1988-08-23 | 1988-08-23 | |
PCT/US1988/002816 WO1989003429A1 (en) | 1987-08-28 | 1988-08-24 | Recombinant avipox virus |
Publications (2)
Publication Number | Publication Date |
---|---|
ATA900788A true ATA900788A (de) | 1995-05-15 |
AT408549B AT408549B (de) | 2001-12-27 |
Family
ID=27492413
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT0900788A AT408549B (de) | 1987-08-28 | 1988-08-24 | Virushältiger impfstoff, rekombinantes virus und verfahren zum exprimieren eines genproduktes |
Country Status (17)
Country | Link |
---|---|
JP (3) | JP3348156B2 (de) |
KR (1) | KR970011149B1 (de) |
AR (1) | AR241939A1 (de) |
AT (1) | AT408549B (de) |
AU (2) | AU2427588A (de) |
BE (1) | BE1002134A5 (de) |
CH (2) | CH679933A5 (de) |
DE (4) | DE10399031I1 (de) |
DK (1) | DK175904B1 (de) |
FR (1) | FR2621487B1 (de) |
GB (1) | GB2217718B (de) |
IL (1) | IL87581A0 (de) |
IT (1) | IT1229484B (de) |
LU (2) | LU90951I2 (de) |
NL (4) | NL195051C (de) |
NZ (1) | NZ225970A (de) |
WO (1) | WO1989003429A1 (de) |
Families Citing this family (116)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5338683A (en) * | 1981-12-24 | 1994-08-16 | Health Research Incorporated | Vaccinia virus containing DNA sequences encoding herpesvirus glycoproteins |
US5505941A (en) * | 1981-12-24 | 1996-04-09 | Health Research, Inc. | Recombinant avipox virus and method to induce an immune response |
US7045313B1 (en) | 1982-11-30 | 2006-05-16 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant vaccinia virus containing a chimeric gene having foreign DNA flanked by vaccinia regulatory DNA |
DE10399031I1 (de) * | 1987-08-28 | 2004-01-29 | Health Research Inc | Rekombinante Viren. |
US5286639A (en) * | 1987-09-16 | 1994-02-15 | Nippon Zeon Co., Ltd. | Recombinant avipoxvirus |
DE3813093A1 (de) * | 1988-04-19 | 1989-11-09 | Immuno Ag | Rekombinantes plasmid, verfahren zum herstellen eines rekombinanten avipoxvirus, rekombinantes avipoxvirus und dessen verwendung |
US5631154A (en) * | 1988-06-10 | 1997-05-20 | Therion Biologics, Incorporated | Self assembled, defective, non-self-propagating lentivirus particles |
EP0353851B1 (de) * | 1988-06-24 | 1994-01-19 | Btg International Limited | Nichtessentielle Geflügelpockenvirus-Regionen |
US5093258A (en) * | 1988-08-26 | 1992-03-03 | Therion Biologics Corporation | Recombinant fowlpox virus and recombination vector |
CA2001001A1 (en) * | 1988-10-21 | 1990-04-21 | Matthew M. Binns | Fowlpox virus promoter |
US6248333B1 (en) | 1990-04-04 | 2001-06-19 | Health Research Inc. | Isolated nucleic acid sequence of equine herpesvirus type 1 glycoprotein D (EHV-1 gD) |
US5204243A (en) * | 1990-02-14 | 1993-04-20 | Health Research Incorporated | Recombinant poxvirus internal cores |
MY109299A (en) * | 1990-08-15 | 1996-12-31 | Virogenetics Corp | Recombinant pox virus encoding flaviviral structural proteins |
US5514375A (en) * | 1990-08-15 | 1996-05-07 | Virogenetics Corporation | Flavivirus recombinant poxvirus vaccine |
FR2668064B1 (fr) * | 1990-10-23 | 1994-12-16 | Transgene Sa | Composition pharmaceutique pour le traitement ou la prevention d'une tumeur maligne. |
US5759841A (en) * | 1990-11-20 | 1998-06-02 | Virogenetics Corporation | Immunological composition of measles virus utilizing recombinant poxvirus |
US5503834A (en) * | 1990-11-20 | 1996-04-02 | Virogenetics Corporation | Measles virus recombinant poxvirus vaccine |
IE68404B1 (en) * | 1990-11-20 | 1996-06-12 | Virogenetics Corp | Measles virus recombinant poxvirus vaccine |
US5756102A (en) * | 1990-11-20 | 1998-05-26 | Virogenetics Corporation | Poxvirus-canine distemper virus (CDV) recombinants and compositions and methods employing the recombinants |
US6309647B1 (en) | 1999-07-15 | 2001-10-30 | Aventis Pasteur | Poxvirus—canine dispemper virus (CDV) or measles virus recombinants and compositions and methods employing the recombinants |
US5338679A (en) * | 1991-01-08 | 1994-08-16 | Her Majesty The Queen In Right Of Canada, As Represented By National Research Council Canada And Forestry Canada | Vertebrate poxvoris expression vector under the control of entomopoxvirus spheroidin gene promoter |
KR100242671B1 (ko) * | 1991-03-07 | 2000-03-02 | 고돈 에릭 | 유전학적으로 처리한 백신 균주 |
US5766598A (en) * | 1991-03-07 | 1998-06-16 | Virogenetics Corporation | Recombinant attenuated ALVAC canarypoxvirus expression vectors containing heterologous DNA segments encoding lentiviral gene products |
AU672581B2 (en) * | 1991-03-07 | 1996-10-10 | Virogenetics Corporation | Immunodeficiency virus recombinant poxvirus vaccine |
US5863542A (en) * | 1991-03-07 | 1999-01-26 | Virogenetics Corporation | Recombinant attenuated ALVAC canaryopox virus containing heterologous HIV or SIV inserts |
US5756101A (en) * | 1991-07-01 | 1998-05-26 | Pasteur Merieux Serums Et Vaccins | Malaria recombinant poxvirus |
US5766597A (en) * | 1991-03-07 | 1998-06-16 | Virogenetics Corporation | Malaria recombinant poxviruses |
JPH06505397A (ja) * | 1991-03-20 | 1994-06-23 | ヴァイロジェネティクス コーポレイション | マラリア組換体ポックスウイルス |
JPH06509235A (ja) * | 1991-07-26 | 1994-10-20 | ヴァイロジェネティクス コーポレイション | 伝染性ファブリキウス嚢病ウイルス組換えポックスウイルスワクチン |
EP1380651A2 (de) * | 1991-08-26 | 2004-01-14 | Baxter Healthcare S.A. | Ein intaktes FPV-tk-Gen enthaltendes rekombinantes Virus der Vogelpocken |
US5443831A (en) * | 1991-10-29 | 1995-08-22 | University Of Delaware | Gene encoding glycoprotein B of Infectious Laryngotracheitis Virus |
US6497882B1 (en) | 1992-01-13 | 2002-12-24 | Syntro Corporation | Recombinant swinepox virus |
US6328975B1 (en) | 1992-01-13 | 2001-12-11 | Syntro Corporation | Recombinant swinepox virus |
ES2236684T3 (es) * | 1992-01-13 | 2005-07-16 | Virogenetics Corporation | Vacuna del virus vaccinia recombinante procedente del virus de la enfermedad de marek. |
US5869312A (en) * | 1992-01-13 | 1999-02-09 | Syntro Corporation | Recombinant swinepox virus |
US6033904A (en) * | 1992-01-13 | 2000-03-07 | Syntro Corporation | Recombinant swinepox virus |
US6251403B1 (en) | 1992-01-13 | 2001-06-26 | Syntro Corporation | Recombinant swinepox virus |
US6127163A (en) * | 1992-01-13 | 2000-10-03 | Syntro Corporation | Recombinant swinepox virus |
EP0662139A1 (de) * | 1992-09-21 | 1995-07-12 | Chiron Corporation | Rekombinierender retrovirus-vektor gegen felv und/oder fiv |
US6136318A (en) * | 1993-02-26 | 2000-10-24 | Cochran; Mark D. | Recombinant fowlpox viruses and uses thereof |
AU727278B2 (en) * | 1993-02-26 | 2000-12-07 | Syntro Corporation | Recombinant fowlpox viruses and uses thereof II |
US5925358A (en) * | 1993-02-26 | 1999-07-20 | Syntro Corporation | Recombinant fowlpox viruses and uses thereof |
AU6299594A (en) * | 1993-02-26 | 1994-09-14 | Nippon Zeon Co., Ltd. | Recombinant fowlpox virus s-fpv-043 and uses thereof |
US5496731A (en) * | 1993-03-25 | 1996-03-05 | Xu; Hong-Ji | Broad-spectrum tumor suppressor genes, gene products and methods for tumor suppressor gene therapy |
US5843742A (en) * | 1994-12-16 | 1998-12-01 | Avigen Incorporated | Adeno-associated derived vector systems for gene delivery and integration into target cells |
EP0753581A1 (de) | 1995-07-10 | 1997-01-15 | Immuno Ag | Verbesserte rekombinante eukaryotische zytoplasmatische Viren, Methode ihrer Herstellung und ihrer Verwendung als Impfstoffe |
US5858373A (en) * | 1995-12-01 | 1999-01-12 | Virogenetics Corporation | Recombinant poxvirus-feline infectious peritionitis virus, compositions thereof and methods for making and using them |
CA2261989C (en) | 1996-07-25 | 2008-09-30 | Therion Biologics Corporation | Recombinant pox virus for immunization against tumor-associated antigens |
US6106825A (en) * | 1997-05-07 | 2000-08-22 | University Of Florida | Entomopoxvirus-vertebrate gene delivery vector and method |
WO1999007869A1 (en) * | 1997-08-05 | 1999-02-18 | University Of Florida | Live recombinant vaccine comprising inefficiently or non-replicating virus |
US6248582B1 (en) * | 1997-10-08 | 2001-06-19 | Imran Khan | Gene deleted recombinant FeLV proviral DNA for production of vaccines against FeLV |
JPH11165762A (ja) | 1997-12-01 | 1999-06-22 | Lintec Corp | チップ体搬送用カバーテープおよび封止構造体 |
US20020147143A1 (en) | 1998-03-18 | 2002-10-10 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
US20030235557A1 (en) | 1998-09-30 | 2003-12-25 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US6200560B1 (en) | 1998-10-20 | 2001-03-13 | Avigen, Inc. | Adeno-associated virus vectors for expression of factor VIII by target cells |
US6221349B1 (en) | 1998-10-20 | 2001-04-24 | Avigen, Inc. | Adeno-associated vectors for expression of factor VIII by target cells |
US7935805B1 (en) | 1998-12-31 | 2011-05-03 | Novartis Vaccines & Diagnostics, Inc | Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof |
CA2360347C (en) | 1998-12-31 | 2013-05-07 | Chiron Corporation | Improved expression of hiv polypeptides and production of virus-like particles |
CN1379819A (zh) | 1999-06-28 | 2002-11-13 | 俄克拉荷马州医学研究基金会 | 具有催化活性的重组memapsin蛋白酶及其应用方法 |
CA2400842C (en) | 2000-02-23 | 2013-01-15 | Smithkline Beecham Biologicals S.A. | Novel compounds |
WO2002000174A2 (en) | 2000-06-28 | 2002-01-03 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
DE60239317D1 (de) | 2001-01-12 | 2011-04-14 | Novartis Vaccines & Diagnostic | Nukleinsäure mukosale immunisierung |
PT1370668E (pt) * | 2001-03-08 | 2006-06-30 | Akzo Nobel Nv | Vacinas de vector baseadas em leporipox |
JP4499311B2 (ja) * | 2001-04-27 | 2010-07-07 | シャープ株式会社 | 放送受信端末 |
EP1988097A1 (de) | 2001-05-09 | 2008-11-05 | Corixa Corporation | Zusammensetzungen und Verfahren zur Behandlung und Diagnose von Prostatakrebs |
AU2002320314A1 (en) | 2001-07-05 | 2003-01-21 | Chiron, Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
EP1409694A4 (de) | 2001-07-05 | 2006-02-08 | Chiron Corp | Antigene typ-b- und/oder typ-c-hiv-polypeptide codierende polynukleotide, polypeptide und deren verwendungen |
WO2003053220A2 (en) | 2001-12-17 | 2003-07-03 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of inflammatory bowel disease |
HUE026376T2 (en) | 2003-01-06 | 2016-05-30 | Corixa Corp | Certain aminoalkyl glucosamide phosphate compounds and their use |
US7960522B2 (en) | 2003-01-06 | 2011-06-14 | Corixa Corporation | Certain aminoalkyl glucosaminide phosphate compounds and their use |
US20070073048A1 (en) | 2003-05-15 | 2007-03-29 | Ying Lian | Hiv polynucleotides and polypeptides derived from botswana mj4 |
US7261882B2 (en) | 2003-06-23 | 2007-08-28 | Reagents Of The University Of Colorado | Methods for treating neuropathic pain by administering IL-10 polypeptides |
EP2305294B1 (de) | 2004-09-22 | 2015-04-01 | GlaxoSmithKline Biologicals SA | Immunogene Zusammensetzung zur Verwendung zur Impfung gegen Staphylokokken |
WO2007081447A2 (en) | 2005-11-22 | 2007-07-19 | Novartis Vaccines And Diagnostics, Inc. | Norovirus and sapovirus antigens |
CA2636424A1 (en) | 2006-01-09 | 2007-10-25 | The Regents Of The University Of California | Immunostimulatory combinations of tnfrsf, tlr, nlr, rhr, purinergic receptor, and cytokine receptor agonists for vaccines and tumor immunotherapy |
EP2397856B1 (de) | 2006-03-14 | 2013-11-13 | Oregon Health and Science University | Methoden zur Detektion einer Mycobakterium tuberculosis Infektion |
US8188214B2 (en) | 2007-02-28 | 2012-05-29 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Brachyury polypeptides and methods for use |
WO2009049351A1 (en) | 2007-10-15 | 2009-04-23 | The University Of Queensland | Construct system and uses therefor |
US8691502B2 (en) | 2008-10-31 | 2014-04-08 | Tremrx, Inc. | T-cell vaccination with viral vectors via mechanical epidermal disruption |
AU2010203223B9 (en) | 2009-01-05 | 2015-10-08 | Epitogenesis Inc. | Adjuvant compositions and methods of use |
WO2010099472A2 (en) | 2009-02-27 | 2010-09-02 | The U.S.A. Of America, As Represented By The Secretary, Department Of Health And Human Services | Spanx-b polypeptides and their use |
US8961989B2 (en) | 2009-11-20 | 2015-02-24 | Oregon Health & Science University | Methods for producing an immune response to tuberculosis |
WO2011106705A2 (en) | 2010-02-26 | 2011-09-01 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Dna-protein vaccination protocols |
US9795658B2 (en) | 2010-04-20 | 2017-10-24 | Admedus Vaccines Pty Ltd | Expression system for modulating an immune response |
US9428565B2 (en) | 2011-01-31 | 2016-08-30 | The General Hospital Corporation | Treatment and bioluminescent visualization using multimodal TRAIL molecules |
WO2012151272A2 (en) | 2011-05-02 | 2012-11-08 | Tremrx, Inc. | T-cell vaccination with viral vectors via mechanical epidermal disruption |
US20150030586A1 (en) | 2011-06-21 | 2015-01-29 | Sarah Ellen Warren | Compositions and methods for the therapy and diagnosis of cancer |
BR112013032410A2 (pt) | 2011-06-24 | 2017-01-17 | Epitogenesis Inc | composições farmacêuticas compreendendo uma combinação de veículos, vitaminas, taninos e flavonoides de seleção como imunomoduladores específicos de antígeno |
US20150004144A1 (en) | 2011-12-02 | 2015-01-01 | The General Hospital Corporation | Differentiation into brown adipocytes |
US9605074B2 (en) | 2012-08-30 | 2017-03-28 | The General Hospital Corporation | Multifunctional nanobodies for treating cancer |
WO2014043535A1 (en) | 2012-09-14 | 2014-03-20 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Compositions for the treatment of cancer |
ES2752190T3 (es) | 2012-09-14 | 2020-04-03 | Us Health | Proteína Brachyury, vectores adenovirales que codifican proteína Brachyury y su uso |
SG10201912901YA (en) | 2013-04-17 | 2020-02-27 | Genzyme Corp | Compositions and methods for treating and preventing macular degeneration |
AU2014268603B2 (en) | 2013-05-21 | 2018-03-22 | President And Fellows Of Harvard College | Engineered heme-binding compositions and uses thereof |
US10172916B2 (en) | 2013-11-15 | 2019-01-08 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of treating heart failure with agonists of hypocretin receptor 2 |
CA2938828A1 (en) | 2014-02-06 | 2015-08-13 | Genzyme Corporation | Compositions and methods for treating and preventing macular degeneration |
JP7095990B2 (ja) | 2014-09-18 | 2022-07-05 | シーダーズ-サイナイ メディカル センター | 線維症を治療するための組成物及び方法 |
JP2018511655A (ja) | 2015-03-20 | 2018-04-26 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | ボルデテラ属に対するワクチン接種における使用のための免疫原性組成物 |
EP3283529B1 (de) | 2015-04-17 | 2023-06-07 | The General Hospital Corporation | Wirkstoffe, systeme und verfahren zur behandlung von krebs |
CN107708718B (zh) | 2015-04-22 | 2022-01-11 | 西达-赛奈医疗中心 | 用于治疗2型糖尿病的肠内递送的苦味寡肽 |
EP4276106A3 (de) | 2015-05-13 | 2024-01-24 | The United States of America as represented by the Secretary of the Department of Health and Human Services | Methoden und zusammensetzungen beruhend auf konstruktenenthaltend konservierte elemente zur induktion einer immunantwort |
WO2016196366A1 (en) | 2015-05-29 | 2016-12-08 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Extension of replicative lifespan in diseases of premature aging using p53 isoforms |
EP3313863B1 (de) | 2015-06-29 | 2020-12-23 | The Board of Trustees of the Leland Stanford Junior University | Degronfusionskonstrukte und verfahren zur steuerung der proteinproduktion |
EP3386593A4 (de) | 2015-12-09 | 2019-07-24 | Admedus Vaccines Pty Ltd | Immunmodulierende zusammensetzung zur behandlung |
WO2018018082A1 (en) | 2016-07-26 | 2018-02-01 | The Australian National University | Immunostimulatory compositions and uses therefor |
US10917454B1 (en) | 2019-08-01 | 2021-02-09 | Rohde & Schwarz Gmbh & Co. Kg | System and method for ATC voice quality assurance |
WO2023070072A1 (en) | 2021-10-21 | 2023-04-27 | The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone | Retroelement-generated transcription factor decoys |
WO2023077147A2 (en) | 2021-11-01 | 2023-05-04 | Pellis Therapeutics, Inc. | T-cell vaccines for patients with reduced humoral immunity |
WO2023081756A1 (en) | 2021-11-03 | 2023-05-11 | The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone | Precise genome editing using retrons |
WO2023141602A2 (en) | 2022-01-21 | 2023-07-27 | Renagade Therapeutics Management Inc. | Engineered retrons and methods of use |
WO2023183589A1 (en) | 2022-03-25 | 2023-09-28 | The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone | Rt-dna fidelity and retron genome editing |
WO2023183588A1 (en) | 2022-03-25 | 2023-09-28 | The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone | Methods of assessing engineered retron activity, and uses thereof |
WO2023183627A1 (en) | 2022-03-25 | 2023-09-28 | The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone | Production of reverse transcribed dna (rt-dna) using a retron reverse transcriptase from exogenous rna |
WO2024020346A2 (en) | 2022-07-18 | 2024-01-25 | Renagade Therapeutics Management Inc. | Gene editing components, systems, and methods of use |
WO2024044673A1 (en) | 2022-08-24 | 2024-02-29 | The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone | Dual cut retron editors for genomic insertions and deletions |
WO2024044723A1 (en) | 2022-08-25 | 2024-02-29 | Renagade Therapeutics Management Inc. | Engineered retrons and methods of use |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK489481A (da) * | 1980-11-10 | 1982-05-11 | Searle & Co | Plasmidvektor og frmgangsmaade til fremstilling deraf |
US4603112A (en) * | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
JPH0795954B2 (ja) * | 1982-11-30 | 1995-10-18 | アメリカ合衆国 | 外来性遺伝子発現のためのポックスウイルス組換え体の製造方法 |
FR2563434B1 (fr) * | 1984-04-25 | 1986-07-25 | Transgene Sa | Vaccin contre la rage et procede pour sa preparation |
EP0190254A4 (de) * | 1984-07-05 | 1987-03-09 | Genex Corp | Kloniertes gen, verfahren zu dessen herstellung und seine verwendung. |
DD235669A1 (de) * | 1985-03-26 | 1986-05-14 | Akad Wissenschaften Ddr | Verfahren zur herstellung eines blv-kodierten huellproteins |
US5032520A (en) * | 1985-03-29 | 1991-07-16 | National Research Development Corporation | DNA sequences encoding infectious bronchitis virus spike protein |
EP0213894A3 (de) * | 1985-08-23 | 1987-10-21 | Advanced Genetics Research Institute | Defektive Viruspartikelimpfstoffe und Verfahren zur Anwendung derselben |
AU607399B2 (en) * | 1985-09-09 | 1991-03-07 | Cetus Corporation | Infectious recombinant virus vaccine for feline leukemia |
GR862412B (en) * | 1985-09-25 | 1987-01-23 | Oncogen | Vaccines and immuinoassays for acquired immune deficiency syndrome |
AU602875B2 (en) * | 1985-12-18 | 1990-11-01 | British Technology Group Limited | Newcastle disease virus gene clones |
AU8075787A (en) * | 1986-09-22 | 1988-04-07 | Australian National University, The | Recombinant poxviruses |
WO1988002022A1 (en) * | 1986-09-22 | 1988-03-24 | Commonwealth Scientific And Industrial Research Or | Recombinant poxviruses |
EP0261940A3 (de) * | 1986-09-23 | 1989-07-05 | Applied Biotechnology, Inc. | Pseudorabies-Impfstoffe und DNS-Vektoren zur Rekombination mit Poxviren |
EP0284416B1 (de) * | 1987-03-27 | 1995-02-22 | Nippon Zeon Co., Ltd. | Rekombinantes Avipoxvirus |
DE10399031I1 (de) * | 1987-08-28 | 2004-01-29 | Health Research Inc | Rekombinante Viren. |
GB8724885D0 (en) * | 1987-10-23 | 1987-11-25 | Binns M M | Fowlpox virus promotors |
FR2632863B2 (fr) * | 1987-10-29 | 1990-08-31 | Transgene Sa | Virus du fowlpox recombinant et vaccins derives de ces virus |
EP0353851B1 (de) * | 1988-06-24 | 1994-01-19 | Btg International Limited | Nichtessentielle Geflügelpockenvirus-Regionen |
DE4090351T1 (de) * | 1989-03-08 | 1997-07-24 | Health Research Inc | Rekombinantes Pockenvirus-Wirtsselektionssystem |
EP0550553B1 (de) * | 1990-09-25 | 2000-07-12 | Cantab Pharmaceuticals Research Limited | Bei einer transkomplementenden zellinie erzeugter defektiver virenimpfstoff |
-
1987
- 1987-08-24 DE DE2003199031 patent/DE10399031I1/de active Pending
- 1987-08-24 DE DE2003199032 patent/DE10399032I1/de active Pending
-
1988
- 1988-08-24 KR KR1019890700753A patent/KR970011149B1/ko not_active IP Right Cessation
- 1988-08-24 WO PCT/US1988/002816 patent/WO1989003429A1/en active Application Filing
- 1988-08-24 DE DE3890874A patent/DE3890874C5/de not_active Expired - Lifetime
- 1988-08-24 CH CH1652/89A patent/CH679933A5/de not_active IP Right Cessation
- 1988-08-24 AU AU24275/88A patent/AU2427588A/en not_active Abandoned
- 1988-08-24 DE DE2002199049 patent/DE10299049I1/de active Pending
- 1988-08-24 AT AT0900788A patent/AT408549B/de not_active IP Right Cessation
- 1988-08-24 CH CH1444/91A patent/CH679934A5/de not_active IP Right Cessation
- 1988-08-24 GB GB8908921A patent/GB2217718B/en not_active Expired - Lifetime
- 1988-08-24 NL NL8820679A patent/NL195051C/nl not_active IP Right Cessation
- 1988-08-24 JP JP50771588A patent/JP3348156B2/ja not_active Expired - Lifetime
- 1988-08-28 IL IL87581A patent/IL87581A0/xx not_active IP Right Cessation
- 1988-08-29 NZ NZ225970A patent/NZ225970A/xx unknown
- 1988-08-29 BE BE8800978A patent/BE1002134A5/fr not_active IP Right Cessation
- 1988-08-29 FR FR888811334A patent/FR2621487B1/fr not_active Expired - Lifetime
- 1988-08-29 IT IT8821772A patent/IT1229484B/it active
- 1988-08-29 AR AR88311787A patent/AR241939A1/es active
-
1989
- 1989-04-27 DK DK198902036A patent/DK175904B1/da active Protection Beyond IP Right Term
-
1995
- 1995-04-05 AU AU16288/95A patent/AU690210B2/en not_active Expired
-
2001
- 2001-10-09 JP JP2001311076A patent/JP2002186494A/ja active Pending
-
2002
- 2002-03-15 JP JP2002071416A patent/JP3826055B2/ja not_active Expired - Lifetime
- 2002-09-04 LU LU90951C patent/LU90951I2/fr unknown
-
2003
- 2003-07-09 NL NL300130C patent/NL300130I2/nl unknown
- 2003-09-05 LU LU91039C patent/LU91039I2/fr unknown
- 2003-11-25 NL NL300139C patent/NL300139I1/nl unknown
- 2003-11-25 NL NL300138C patent/NL300138I2/nl unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATA900788A (de) | Virushältiger impfstoff, rekombinantes virus und verfahren zum exprimieren eines genproduktes | |
DE3773974D1 (de) | Verfahren und apparat zum fuellen und verpacken. | |
DE3852234D1 (de) | Apparat zum Fördern von Bogen und Verfahren zum Fördern von Bogen. | |
DE68923569D1 (de) | Verfahren und Apparat zum Formatieren eines Dokumentes. | |
PT71296B (en) | Process for preparing non-passageable viruses and method for maintaining replicating and expressing at least a portion of the genome of an np-virus comprising | |
DE3854083D1 (de) | Apparat und verfahren zum ernten von feldfrüchten. | |
ATE69419T1 (de) | Verfahren und apparat zum vakuumverpacken. | |
DE68928068D1 (de) | Verfahren und Apparat zum Formatieren von Dokumenten | |
DE59007408D1 (de) | Verfahren zum kryptographischen Behandeln von Daten und kryptographisches System. | |
DE68926550D1 (de) | Artikel und Verfahren zum Saugen von verunreinigenden Produkten | |
ATE77321T1 (de) | Verfahren und vorrichtung zum keimfreien fuellen einer verpackung. | |
DE58902097D1 (de) | Verfahren zum vakuumdichten verschliessen eines keramikrohres. | |
ATA143190A (de) | Verfahren und vorrichtung zum entholzen und zum aufbereiten von flachs | |
DE3878495D1 (de) | Verfahren zum schuetzen und isolieren eines katalysator-blocks. | |
DE3669496D1 (de) | Verfahren zum formen eines pulverfoermigen materials. | |
DE69105317D1 (de) | System und Verfahren zum Verpacken von Petrischalen. | |
EP0292293A3 (en) | Newcastle disease virus vaccine and method for the applicaton thereof | |
DE3885138D1 (de) | Verfahren zum Kontrollieren und Auswechseln eines Wickelkörpers. | |
AT361367B (de) | Vorrichtung zum fuellen und entleeren sowie zum gleichzeitigen stapeln und entstapeln von kapseln fuer keramisches gut | |
DE3781468D1 (de) | Verfahren zum trocknen und zur aktivierung eines katalysators. | |
DK44788A (da) | Svaekket cytomegalovirus, vaccine indeholdende et saadant virus og dna-konstruktion | |
DE69011820D1 (de) | Verfahren und Vorrichtung zum Handhaben von Artikeln. | |
DE3862519D1 (de) | Einrichtung und verfahren zum zerteilen eines stapels von flachen gegenstaenden. | |
DE69116498D1 (de) | Verfahren und Vorrichtung zum Trennen des Herzens, der Lungen und der Leber von Geflügeleingeweide | |
DD295595A5 (de) | Verfahren und vorrichtung zum aufeinanderfolgenden foerdern von flachen produkten |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
SZA | Application filed for a certificate of protection |
Free format text: SZ 31/2002, 20020906 |
|
SZA | Application filed for a certificate of protection |
Free format text: ERZEUGNIS: INFLUENZA A/EQUI-2/KENTUCKY/94-REKOMBINANTE DES KANARIENPOCKENVIRUS IN KOMBINATION MIT INFLUENZA A/EQUI-2/NEWMARKET/2/93-REKOMBINATE DES KANARIENPOCKENVIRUS UND MIT CLOSTRIDIUM TETANI-TOXOID Spc suppl protection certif: SZ 26/2003 Filing date: 20030904 Free format text: ERZEUGNIS: INFLUENZA A/EQUI-2/KENTUCKY/94-REKOMBINANTE DES KANARIENPOCKENVIRUS IN KOMBINATION MIT INFLUENZA A/EQUI-2/NEWMARKET/2/93-REKOMBINATE DES KANARIENPOCKENVIRUS Spc suppl protection certif: SZ 27/2003 Filing date: 20030904 |
|
EZF | Grant of a certificate of protection |
Free format text: SZ 27/2003, 20030904, EXPIRES:20130824 Spc suppl protection certif: SZ 27/2003 Filing date: 20030904 Expiry date: 20130824 Free format text: SZ 31/2002, 20020906, EXPIRES:20130824 Spc suppl protection certif: SZ 31/2002 Filing date: 20020906 Expiry date: 20130824 Free format text: SZ 26/2003, 20030904, EXPIRES:20130824 Spc suppl protection certif: SZ 26/2003 Filing date: 20030904 Expiry date: 20130824 |
|
ELA | Expired due to lapse of time | ||
SPCX | Expiry of an spc |
Free format text: PRODUCT NAME: INFLUENZA A/EQUI-2/KENTUCKY/94 (H3N8) - REKOMBINANTE DES KANARIENPOCKENVIRUS UND INFLUENZA A/EQUI-2/NEWMARKET/2/93 (H3N8) -REKOMBINANTE DES KANARIENPOCKENVIRUS; REGISTRATION NO/DATE: EU/2/03/038/001-004 20030306 Spc suppl protection certif: 26/2003 Filing date: 20030904 Expiry date: 20080824 Extension date: 20130824 Effective date: 20130824 Free format text: PRODUCT NAME: INFLUENZA A/EQUI-2/KENTUCKY/94 (H3N8) -REKOMBINANTE DES KANARIENPOCKENVIRUS UND INFLUENZA A/EQUI-2/NEWMARKET/2/93 (H3N8) - REKOMBINANTE DES KANARIENPOCKENVIRUS; REGISTRATION NO/DATE: EU/2/03/037/001-004 20030306 Spc suppl protection certif: 27/2003 Filing date: 20030904 Expiry date: 20080824 Extension date: 20130824 Effective date: 20130824 Free format text: PRODUCT NAME: ENV- UND GAG-FELV UMFASSENDE REKOMBINANTEN DES KANARIENPOCKENVIRUS; NAT. REGISTRATIONNO/DATE: EU/2/02/031/001 UND EU/2/02/031/002 20020308; FIRST REGISTRATION: EU EU/2/02/031/001 UND 20020308 Spc suppl protection certif: 31/2002 Filing date: 20020906 Expiry date: 20080824 Extension date: 20130824 Effective date: 20130824 |