AT333277B - Verfahren zur herstellung von neuen oxazolpyridinen und deren n-oxiden und quaternaren pyridiniumsalzen - Google Patents
Verfahren zur herstellung von neuen oxazolpyridinen und deren n-oxiden und quaternaren pyridiniumsalzenInfo
- Publication number
- AT333277B AT333277B AT508673A AT508673A AT333277B AT 333277 B AT333277 B AT 333277B AT 508673 A AT508673 A AT 508673A AT 508673 A AT508673 A AT 508673A AT 333277 B AT333277 B AT 333277B
- Authority
- AT
- Austria
- Prior art keywords
- quaternar
- pyridines
- oxides
- preparation
- pyridinium salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26289872A | 1972-06-14 | 1972-06-14 | |
BE147896A BE819177R (fr) | 1972-06-14 | 1974-08-26 | Oxazolo- et thiazolopyridines |
Publications (2)
Publication Number | Publication Date |
---|---|
ATA508673A ATA508673A (de) | 1976-03-15 |
AT333277B true AT333277B (de) | 1976-11-10 |
Family
ID=25648082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT508673A AT333277B (de) | 1972-06-14 | 1973-06-08 | Verfahren zur herstellung von neuen oxazolpyridinen und deren n-oxiden und quaternaren pyridiniumsalzen |
Country Status (17)
Country | Link |
---|---|
JP (1) | JPS5943475B2 (fr) |
AR (1) | AR208500A1 (fr) |
AT (1) | AT333277B (fr) |
AU (1) | AU472528B2 (fr) |
BE (2) | BE800868A (fr) |
CA (1) | CA1019741A (fr) |
CS (1) | CS178889B2 (fr) |
DD (1) | DD105237A5 (fr) |
DE (1) | DE2330109A1 (fr) |
DK (1) | DK152050C (fr) |
FI (1) | FI57417C (fr) |
FR (1) | FR2187356B1 (fr) |
GB (1) | GB1421619A (fr) |
LU (1) | LU67786A1 (fr) |
NL (1) | NL184836C (fr) |
SE (2) | SE401675B (fr) |
ZA (1) | ZA733760B (fr) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2527321A1 (de) * | 1975-06-19 | 1976-12-23 | Merck & Co Inc | Oxazol eckige klammer auf 4,5-b eckige klammer zu pyridine |
JPS527992A (en) * | 1975-07-04 | 1977-01-21 | Merck & Co Inc | Oxazolo *4*55b* pyridines |
NL187021C (nl) * | 1975-07-15 | 1991-05-01 | Merck & Co Inc | Werkwijze ter bereiding van een farmaceutisch preparaat met anti-inflammatoire werking, alsmede werkwijze ter bereiding van voor toepassing daarbij geschikte anti-inflammatoir werkzame 2-fenyl-oxazolo-(4,5-b)pyridinederivaten. |
US4011326A (en) * | 1975-07-29 | 1977-03-08 | Merck & Co., Inc. | 2-Substituted oxazolo[4,5-b]pyridine anti-inflammatory agents |
US4753673A (en) * | 1977-07-22 | 1988-06-28 | The Dow Chemical Company | Trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanoic acids and propanols and derivatives thereof and methods of herbicidal use |
EP0001473B1 (fr) * | 1977-08-12 | 1988-07-27 | Imperial Chemical Industries Plc | Acides halogénométhyl-pyridyloxy-phénoxy-alcanecarboxyliques herbicides et dérivés; procédés pour contrôler la croissance de plantes indésirées |
JPS5461182A (en) * | 1977-10-20 | 1979-05-17 | Ishihara Sangyo Kaisha Ltd | 2-phenoxy-5-trifluoromethylpyridine compounds |
JPS5461183A (en) * | 1977-10-21 | 1979-05-17 | Ishihara Sangyo Kaisha Ltd | 2-substituted-5-trifluoromethyl pyridine compounds |
EP0003877B1 (fr) * | 1978-02-15 | 1988-02-03 | Imperial Chemical Industries Plc | Dérivés herbicides du 2-(4(2-pyridyloxy)phénoxy)propane, procédés pour leur préparation, et herbicides les contenant |
JPS55130840U (fr) * | 1979-03-12 | 1980-09-16 | ||
JPS55124763A (en) * | 1979-03-19 | 1980-09-26 | Ishihara Sangyo Kaisha Ltd | 5-trifluoromethyl-2-pyridone derivative |
GB8333514D0 (en) * | 1983-12-16 | 1984-01-25 | Erba Farmitalia | Tetrahydrothiazolo(5 4-c)pyridine derivatives |
FR2652085A1 (fr) * | 1989-09-20 | 1991-03-22 | Science Organisation | Nouveau procede de synthese de derives d'oxazolopyridines. |
PT937075E (pt) * | 1996-11-11 | 2004-05-31 | Altana Pharma Ag | Novas imidazo- e oxazolo-piridinas como inibidores da fosfodiesterese |
SK18542000A3 (sk) * | 1998-06-04 | 2001-12-03 | Abbott Laboratories | Protizápalové zlúčeniny inhibujúce bunkovú adhéziu |
US6232320B1 (en) | 1998-06-04 | 2001-05-15 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
WO2000075145A1 (fr) * | 1999-06-03 | 2000-12-14 | Abbott Laboratories | Composes anti-inflammatoires inhibant l'adhesion cellulaire |
AU2002216649A1 (en) * | 2000-10-31 | 2002-05-15 | Lynn Bonham | Benzoxazole lpaat- beta inhibitors and uses thereof |
US7855289B2 (en) | 2005-08-04 | 2010-12-21 | Sirtris Pharmaceuticals, Inc. | Sirtuin modulating compounds |
US8093401B2 (en) | 2005-08-04 | 2012-01-10 | Sirtris Pharmaceuticals, Inc. | Sirtuin modulating compounds |
US8088928B2 (en) | 2005-08-04 | 2012-01-03 | Sirtris Pharmaceuticals, Inc. | Sirtuin modulating compounds |
WO2007019345A1 (fr) * | 2005-08-04 | 2007-02-15 | Sirtris Pharmaceuticals, Inc. | Dérivés de l’imidazopyridine en tant qu’agents modulant la sirtuine |
TW200916472A (en) | 2007-06-20 | 2009-04-16 | Sirtris Pharmaceuticals Inc | Sirtuin modulating compounds |
US8795630B2 (en) * | 2008-08-29 | 2014-08-05 | Treventis Corporation | Butyrylcholinesterase ligands as diagnostic tools and treatment for diseases of the nervous system |
PE20120057A1 (es) | 2008-12-19 | 2012-02-24 | Sirtris Pharmaceuticals Inc | Compuestos de tiazolopiridina moduladores de sirtuina |
EP2482660A4 (fr) * | 2009-09-30 | 2013-04-17 | Sumitomo Chemical Co | Composition et procédé permettant de lutter contre les arthropodes nuisibles |
KR20130051507A (ko) | 2010-09-15 | 2013-05-20 | 에프. 호프만-라 로슈 아게 | 아자벤조티아졸 화합물, 조성물 및 사용 방법 |
BR112013016022B1 (pt) | 2010-12-24 | 2019-05-07 | Sumitomo Chemical Company, Limited | Composto heterocíclico fundido e uso do mesmo para controle de peste. |
WO2015200650A1 (fr) * | 2014-06-25 | 2015-12-30 | Epizyme, Inc. | Composés hétéroaryles bicycliques fusionnés en 6,5 ou benzènes substitués |
JP2017537909A (ja) | 2014-12-02 | 2017-12-21 | バイエル・クロップサイエンス・アクチェンゲゼルシャフト | 有害生物防除剤としての二環式化合物 本出願は、新規二環式化合物、それら化合物を含んでいる組成物、害虫(animal pest)を防除するためのそれらの使用、並びに、それらを調製するための方法及び中間体に関する。 |
WO2017127627A1 (fr) * | 2016-01-21 | 2017-07-27 | The University Of North Carolina At Chapel Hill | Composés pour traiter les trypanosomes et les pathogènes neurologiques et leurs utilisations |
KR102440762B1 (ko) * | 2016-07-07 | 2022-09-05 | 호도가야 가가쿠 고교 가부시키가이샤 | 벤조아졸 고리 구조를 가지는 화합물 및 유기 일렉트로루미네센스 소자 |
-
1973
- 1973-03-12 AR AR248527A patent/AR208500A1/es active
- 1973-05-22 FI FI1657/73A patent/FI57417C/fi active
- 1973-05-24 DK DK284973A patent/DK152050C/da not_active IP Right Cessation
- 1973-05-25 SE SE7307412A patent/SE401675B/xx unknown
- 1973-05-30 NL NLAANVRAGE7307582,A patent/NL184836C/xx not_active IP Right Cessation
- 1973-06-04 ZA ZA00733760A patent/ZA733760B/xx unknown
- 1973-06-04 AU AU56511/73A patent/AU472528B2/en not_active Expired
- 1973-06-05 CA CA173,275A patent/CA1019741A/en not_active Expired
- 1973-06-08 AT AT508673A patent/AT333277B/de active
- 1973-06-11 GB GB2763273A patent/GB1421619A/en not_active Expired
- 1973-06-12 CS CS7300004243A patent/CS178889B2/cs unknown
- 1973-06-12 DD DD171559A patent/DD105237A5/xx unknown
- 1973-06-13 LU LU67786A patent/LU67786A1/xx unknown
- 1973-06-13 BE BE132231A patent/BE800868A/fr not_active IP Right Cessation
- 1973-06-13 FR FR7321443A patent/FR2187356B1/fr not_active Expired
- 1973-06-13 DE DE2330109A patent/DE2330109A1/de not_active Withdrawn
- 1973-06-14 JP JP48066453A patent/JPS5943475B2/ja not_active Expired
-
1974
- 1974-08-26 BE BE147896A patent/BE819177R/fr not_active IP Right Cessation
-
1976
- 1976-04-14 SE SE7604385A patent/SE432767B/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NL184836B (nl) | 1989-06-16 |
SE7604385L (sv) | 1976-04-14 |
DK152050B (da) | 1988-01-25 |
FI57417B (fi) | 1980-04-30 |
GB1421619A (en) | 1976-01-21 |
LU67786A1 (fr) | 1973-08-16 |
SE432767B (sv) | 1984-04-16 |
AR208500A1 (es) | 1977-02-15 |
BE800868A (fr) | 1973-12-13 |
JPS4961195A (fr) | 1974-06-13 |
FR2187356A1 (fr) | 1974-01-18 |
ZA733760B (en) | 1975-01-29 |
FR2187356B1 (fr) | 1977-01-28 |
AU472528B2 (en) | 1976-05-27 |
JPS5943475B2 (ja) | 1984-10-22 |
ATA508673A (de) | 1976-03-15 |
CS178889B2 (en) | 1977-10-31 |
DK152050C (da) | 1988-07-18 |
NL184836C (nl) | 1989-11-16 |
DD105237A5 (fr) | 1974-04-12 |
CA1019741A (en) | 1977-10-25 |
BE819177R (fr) | 1975-02-26 |
AU5651173A (en) | 1974-12-05 |
NL7307582A (fr) | 1973-12-18 |
FI57417C (fi) | 1980-08-11 |
DE2330109A1 (de) | 1974-01-03 |
SE401675B (sv) | 1978-05-22 |
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