AR241159A2 - Un procedimiento para preparar un compuesto de 2-oxindol-1-carboxamida y compuesto obtenido - Google Patents
Un procedimiento para preparar un compuesto de 2-oxindol-1-carboxamida y compuesto obtenidoInfo
- Publication number
- AR241159A2 AR241159A2 AR30025985A AR30025985A AR241159A2 AR 241159 A2 AR241159 A2 AR 241159A2 AR 30025985 A AR30025985 A AR 30025985A AR 30025985 A AR30025985 A AR 30025985A AR 241159 A2 AR241159 A2 AR 241159A2
- Authority
- AR
- Argentina
- Prior art keywords
- formula
- oxindole
- substituted
- carboxamide
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
UN PROCEDIMIENTO PARA PREPARAR UN COMPUESTO DE 2-OXINDOL-1-CARBOXAMIDA DE FORMULA (I), O UNA SAL FARMACEUTICAMENTE ACEPTABLE DEL MISMO; R ES H, HALOGENO O TRIFLUOROMETILO; R1 ES ENTRE OTRAS ALQUILO, TRIFLUOROMETILO, FENOXIMETILO; R2 ES ENTRE OTROS ALQUILO, CICLOHEXILO, BENCILO, FENILO, FLUOROFENILO; EL PROCESO SE BASA EN REACCIONAR UN COMPUESTO DE FORMULA (V) CON UN DERIVADO ACTIVADO DE UN ACIDO CARBOXILICO D FORMULA R1-C(O)-OH, EN UN SOLVENTE INERTE; TENIENDO X, R1 Y R2 LOS SIGNIFICADOS MENCIONADOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60735684A | 1984-05-04 | 1984-05-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AR241159A1 AR241159A1 (es) | 1991-12-30 |
| AR241159A2 true AR241159A2 (es) | 1991-12-30 |
Family
ID=24431933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR300259A AR241159A1 (es) | 1984-05-04 | 1985-05-02 | Un procedimiento para preparar un compuesto de 2-oxindol-1-carboxamida y compuesto obtenido |
Country Status (25)
| Country | Link |
|---|---|
| JP (1) | JPS60243068A (es) |
| KR (1) | KR870000497B1 (es) |
| AR (1) | AR241159A1 (es) |
| BG (2) | BG60208B2 (es) |
| CS (1) | CS252828B2 (es) |
| DD (1) | DD232916A5 (es) |
| EG (1) | EG17193A (es) |
| ES (2) | ES8609248A1 (es) |
| FI (1) | FI80016C (es) |
| HU (1) | HU196057B (es) |
| IE (1) | IE851103L (es) |
| IN (1) | IN161509B (es) |
| MA (1) | MA20424A1 (es) |
| MW (1) | MW1685A1 (es) |
| MX (1) | MX5839A (es) |
| NO (1) | NO163132C (es) |
| OA (1) | OA08098A (es) |
| PL (2) | PL145416B1 (es) |
| PT (1) | PT80375B (es) |
| RO (2) | RO94455B (es) |
| RU (1) | RU2017729C1 (es) |
| SU (1) | SU1468413A3 (es) |
| YU (1) | YU44998B (es) |
| ZA (1) | ZA853324B (es) |
| ZW (1) | ZW7885A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5047554A (en) * | 1989-04-18 | 1991-09-10 | Pfizer Inc. | 3-substituted-2-oxindole derivatives |
| IL95880A (en) * | 1989-10-13 | 1995-12-31 | Pfizer | Use of 3-Transformed History of 2-Oxindole for the Preparation of Pharmaceuticals for Inhibition of Interlaukio-1 Biosynthesis |
-
1985
- 1985-04-08 IN IN288/DEL/85A patent/IN161509B/en unknown
- 1985-04-30 PT PT80375A patent/PT80375B/pt unknown
- 1985-04-30 YU YU730/85A patent/YU44998B/xx unknown
- 1985-05-02 JP JP60095275A patent/JPS60243068A/ja active Granted
- 1985-05-02 IE IE851103A patent/IE851103L/xx unknown
- 1985-05-02 DD DD85275898A patent/DD232916A5/de not_active IP Right Cessation
- 1985-05-02 AR AR300259A patent/AR241159A1/es active
- 1985-05-02 EG EG275/85A patent/EG17193A/xx active
- 1985-05-03 ES ES542813A patent/ES8609248A1/es not_active Expired
- 1985-05-03 PL PL1985253203A patent/PL145416B1/pl unknown
- 1985-05-03 RO RO123678A patent/RO94455B/ro unknown
- 1985-05-03 MA MA20648A patent/MA20424A1/fr unknown
- 1985-05-03 OA OA58583A patent/OA08098A/xx unknown
- 1985-05-03 BG BG70071A patent/BG60208B2/xx unknown
- 1985-05-03 ZW ZW78/85A patent/ZW7885A1/xx unknown
- 1985-05-03 PL PL1985257892A patent/PL147508B1/pl unknown
- 1985-05-03 RO RO118604A patent/RO91141B/ro unknown
- 1985-05-03 FI FI851756A patent/FI80016C/fi not_active IP Right Cessation
- 1985-05-03 MW MW16/85A patent/MW1685A1/xx unknown
- 1985-05-03 NO NO851774A patent/NO163132C/no not_active IP Right Cessation
- 1985-05-03 MX MX583985A patent/MX5839A/es unknown
- 1985-05-03 ZA ZA853324A patent/ZA853324B/xx unknown
- 1985-05-03 KR KR1019850003013A patent/KR870000497B1/ko not_active IP Right Cessation
- 1985-05-04 RU SU853891002A patent/RU2017729C1/ru active
- 1985-05-04 CS CS853202A patent/CS252828B2/cs not_active IP Right Cessation
- 1985-05-31 HU HU851693A patent/HU196057B/hu unknown
-
1986
- 1986-01-27 ES ES551275A patent/ES8707182A1/es not_active Expired
- 1986-05-12 SU SU864027453A patent/SU1468413A3/ru active
-
1992
- 1992-07-08 BG BG96583A patent/BG60207B2/xx unknown
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