AR209755A1 - Nuevos compuestos derivados de la 2-hidroxi-c1-4-alquil sustituido benzofenoxima,utiles como productos intermediarios,que son terapeuticamente inactivos y particularmente apropiados para la preparacion de los correspondientes derivados benzisoxozolicos biologicamente activos - Google Patents

Nuevos compuestos derivados de la 2-hidroxi-c1-4-alquil sustituido benzofenoxima,utiles como productos intermediarios,que son terapeuticamente inactivos y particularmente apropiados para la preparacion de los correspondientes derivados benzisoxozolicos biologicamente activos

Info

Publication number: AR209755A1
Authority: AR; Argentina
Prior art keywords: benzophenoxima; hidroxi; benzoximate; actives; useful
Prior art date: 1973-10-23

Application number

AR256197A

Other languages

English (en)

Spanish (es)

Original Assignee

Lilly Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-10-23

Filing date

1974-10-23

Publication date

1977-05-31

1974-10-23 Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd

1977-05-31 Application granted granted Critical

1977-05-31 Publication of AR209755A1 publication Critical patent/AR209755A1/es

Links

HOERQTQCTISLFR-UHFFFAOYSA-N [(3-chloro-2,6-dimethoxybenzoyl)-ethylamino] benzoate Chemical compound COC=1C=CC(Cl)=C(OC)C=1C(=O)N(CC)OC(=O)C1=CC=CC=C1 HOERQTQCTISLFR-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D263/57—Aryl or substituted aryl radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Rheumatology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AR256197A 1973-10-23 1974-10-23 Nuevos compuestos derivados de la 2-hidroxi-c1-4-alquil sustituido benzofenoxima,utiles como productos intermediarios,que son terapeuticamente inactivos y particularmente apropiados para la preparacion de los correspondientes derivados benzisoxozolicos biologicamente activos AR209755A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB49259/73A GB1488003A (en)	1973-10-23	1973-10-23	1,2-benzisoxazole derivatives processes for their preparation and their use as pharmaceuticals

Publications (1)

Publication Number	Publication Date
AR209755A1 true AR209755A1 (es)	1977-05-31

Family

ID=10451720

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
AR256197A AR209755A1 (es)	1973-10-23	1974-10-23	Nuevos compuestos derivados de la 2-hidroxi-c1-4-alquil sustituido benzofenoxima,utiles como productos intermediarios,que son terapeuticamente inactivos y particularmente apropiados para la preparacion de los correspondientes derivados benzisoxozolicos biologicamente activos
AR261777A AR213086A1 (es)	1973-10-23	1975-12-29	Procedimiento para la preparacion de derivados de acido 2-(para-sustituido fenil)-benzoxazol-5 o 6-carboxilico,farmaceuticamente activos
AR261776A AR221321A1 (es)	1973-10-23	1975-12-29	Un procedimiento para la preparacion de acidos 3-fenil-1,2-benzisoxazolil-alquilcarboxilicos y sus sales

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
AR261777A AR213086A1 (es)	1973-10-23	1975-12-29	Procedimiento para la preparacion de derivados de acido 2-(para-sustituido fenil)-benzoxazol-5 o 6-carboxilico,farmaceuticamente activos
AR261776A AR221321A1 (es)	1973-10-23	1975-12-29	Un procedimiento para la preparacion de acidos 3-fenil-1,2-benzisoxazolil-alquilcarboxilicos y sus sales

Country Status (27)

Country	Link
US (1)	US3951999A (sv)
JP (2)	JPS5912671B2 (sv)
AR (3)	AR209755A1 (sv)
AT (1)	AT341520B (sv)
AU (1)	AU510909B2 (sv)
BE (1)	BE821406A (sv)
BG (2)	BG25991A3 (sv)
CA (1)	CA1042005A (sv)
CH (2)	CH605864A5 (sv)
CS (1)	CS189671B2 (sv)
DD (1)	DD116830A5 (sv)
DE (1)	DE2450053A1 (sv)
DK (1)	DK552674A (sv)
ES (3)	ES431247A1 (sv)
FR (3)	FR2248041B1 (sv)
GB (1)	GB1488003A (sv)
HU (1)	HU171613B (sv)
IE (1)	IE40078B1 (sv)
IL (3)	IL45880A (sv)
NL (1)	NL7413848A (sv)
NZ (1)	NZ175780A (sv)
PH (1)	PH11022A (sv)
RO (2)	RO74031A (sv)
SE (3)	SE424324B (sv)
SU (3)	SU604491A3 (sv)
YU (1)	YU282474A (sv)
ZA (1)	ZA746594B (sv)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1590587A (en) *	1977-06-28	1981-06-03	Lilly Industries Ltd	Benoxaprofen
US4673746A (en) *	1978-10-06	1987-06-16	Hoechst-Roussel Pharmaceuticals, Inc.	1,2-benzisoxazoloxyacetic acids and related compounds
US4728662A (en) *	1977-11-21	1988-03-01	Hoechst-Roussel Pharmaceuticals Inc.	1,2-benzisoxazoloxyacetic acids and related compounds
NZ189705A (en) *	1978-03-01	1981-07-13	Boots Co Ltd	Benzophenone-hydrazone derivatives and pesticidal compositions intermediates
US4337261A (en) *	1980-07-28	1982-06-29	Hoechst-Roussel Pharmaceuticals Inc.	(1,2-Benzisoxazol)phenoxyacetic acids as diuretics
US4396770A (en) *	1982-04-09	1983-08-02	Hoechst-Roussel Pharmaceuticals Inc.	1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-phenylpiperidines
US4894461A (en) *	1981-04-27	1990-01-16	Hoechst-Roussel Pharmaceuticals, Inc.	3-(γ-chloropropyl)-6-fluoro-1,2-benzisoxazole
US4536578A (en) *	1982-04-09	1985-08-20	Hoechst-Roussel Pharmaceuticals Inc.	1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines
US4609658A (en) *	1982-04-09	1986-09-02	Hoechst-Roussel Pharmaceuticals Inc.	1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted) piperazines useful for reducing blood pressure
US4610988A (en) *	1982-04-09	1986-09-09	Hoechst-Roussel Pharmaceuticals Inc.	1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines useful for alleviating pain
US4374245A (en) *	1982-04-09	1983-02-15	Hoechst-Roussel Pharmaceuticals Inc.	8-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
US4458075A (en) *	1982-04-09	1984-07-03	Hoechst-Roussel Pharmaceuticals Inc.	6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles
US4390544A (en) *	1982-04-09	1983-06-28	Hoechst-Roussel Pharmaceuticals Inc.	{1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl}p
US4420485A (en) *	1982-09-29	1983-12-13	Hoechst-Roussel Pharmaceuticals Inc.	1'-[3-(1,2-Benzisoxazol-3-yl) proply]spiro[benzofuran-2(3H),3' or 4'-piperidines or 3'-pyrrolidines]
FR2540107B1 (fr) *	1983-01-28	1986-10-17	Inst Rech Chim Biolog	Nouveaux derives d'halogenobenzophenone-oxime, utilisation en therapeutique et procede de preparation
FI92189C (sv) *	1986-03-17	1994-10-10	Eisai Co Ltd	Förfarande för framställning av ett som läkemedel användbart difenylmetanderivat
US4898874A (en) *	1986-09-15	1990-02-06	A. H. Robins Company, Inc.	Acetic acid derivatives of 3-aryl-2,1-benzisoxazole and esters and amides thereof
JPH037961U (sv) *	1989-06-14	1991-01-25
US5114960A (en) *	1989-07-20	1992-05-19	Hoffmann-La Roche Inc.	Substituted isoxazole derivatives
US8518980B2 (en) *	2006-02-10	2013-08-27	Summit Corporation Plc	Treatment of Duchenne muscular dystrophy
EP2755961A1 (en) *	2011-09-16	2014-07-23	Pfizer Inc	Solid forms of a transthyretin dissociation inhibitor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH1093669A4 (sv) *	1969-07-17	1971-02-15
FR2093173A5 (en) *	1970-06-04	1972-01-28	Gen Mills Inc	Substituted 2-hydroxybenzophenoximes for - copper extraction

1973
- 1973-10-23 GB GB49259/73A patent/GB1488003A/en not_active Expired
1974
- 1974-10-16 ZA ZA00746594A patent/ZA746594B/xx unknown
- 1974-10-16 US US05/515,131 patent/US3951999A/en not_active Expired - Lifetime
- 1974-10-18 IL IL45880A patent/IL45880A/xx unknown
- 1974-10-21 SE SE7413237A patent/SE424324B/sv unknown
- 1974-10-21 CH CH566077A patent/CH605864A5/xx not_active IP Right Cessation
- 1974-10-21 CH CH1404174A patent/CH595360A5/xx not_active IP Right Cessation
- 1974-10-22 RO RO7480288A patent/RO74031A/ro unknown
- 1974-10-22 DE DE19742450053 patent/DE2450053A1/de not_active Withdrawn
- 1974-10-22 SU SU742091795A patent/SU604491A3/ru active
- 1974-10-22 IE IE2167/74A patent/IE40078B1/xx unknown
- 1974-10-22 DK DK552674A patent/DK552674A/da not_active Application Discontinuation
- 1974-10-22 YU YU02824/74A patent/YU282474A/xx unknown
- 1974-10-22 ES ES431247A patent/ES431247A1/es not_active Expired
- 1974-10-22 RO RO7499777A patent/RO78465A/ro unknown
- 1974-10-22 CA CA212,030A patent/CA1042005A/en not_active Expired
- 1974-10-22 CS CS747227A patent/CS189671B2/cs unknown
- 1974-10-23 BG BG7428023A patent/BG25991A3/xx unknown
- 1974-10-23 AR AR256197A patent/AR209755A1/es active
- 1974-10-23 NL NL7413848A patent/NL7413848A/xx not_active Application Discontinuation
- 1974-10-23 NZ NZ175780A patent/NZ175780A/xx unknown
- 1974-10-23 DD DD181858A patent/DD116830A5/xx unknown
- 1974-10-23 JP JP49122354A patent/JPS5912671B2/ja not_active Expired
- 1974-10-23 FR FR7435535A patent/FR2248041B1/fr not_active Expired
- 1974-10-23 AT AT852374A patent/AT341520B/de not_active IP Right Cessation
- 1974-10-23 PH PH16443A patent/PH11022A/en unknown
- 1974-10-23 HU HU74LI00000266A patent/HU171613B/hu unknown
- 1974-10-23 BG BG7432026A patent/BG26531A4/xx unknown
- 1974-10-23 BE BE6044795A patent/BE821406A/xx not_active IP Right Cessation
1975
- 1975-12-29 AR AR261777A patent/AR213086A1/es active
- 1975-12-29 AR AR261776A patent/AR221321A1/es active
1976
- 1976-01-27 SU SU762315111A patent/SU608476A3/ru active
- 1976-01-28 SU SU762317502A patent/SU795459A3/ru active
- 1976-07-07 ES ES449655A patent/ES449655A1/es not_active Expired
- 1976-07-07 ES ES449654A patent/ES449654A1/es not_active Expired
1977
- 1977-03-18 FR FR7708208A patent/FR2361359A1/fr active Granted
- 1977-05-27 IL IL52179A patent/IL52179A0/xx unknown
- 1977-05-27 IL IL52180A patent/IL52180A0/xx unknown
- 1977-09-14 FR FR7727742A patent/FR2361328A1/fr active Granted
- 1977-09-14 AU AU28801/77A patent/AU510909B2/en not_active Expired
- 1977-09-21 SE SE7710599A patent/SE424325B/sv unknown
- 1977-09-21 SE SE7710600A patent/SE435713B/sv unknown
1981
- 1981-10-23 JP JP56169949A patent/JPS57154174A/ja active Granted

Also Published As

Publication number	Publication date
CA1042005A (en)	1978-11-07
US3951999A (en)	1976-04-20
DK552674A (sv)	1975-06-16
JPS57154174A (en)	1982-09-22
RO78465A (ro)	1982-02-26
BG26531A4 (sv)	1979-04-12
JPS636066B2 (sv)	1988-02-08
ATA852374A (de)	1977-06-15
SU604491A3 (ru)	1978-04-25
AU510909B2 (en)	1980-07-17
RO74031A (ro)	1982-02-01
FR2248041B1 (sv)	1978-09-08
SE7413237L (sv)	1975-04-24
IE40078L (en)	1975-04-23
SU795459A3 (ru)	1981-01-07
FR2248041A1 (sv)	1975-05-16
ZA746594B (en)	1976-06-30
CS189671B2 (en)	1979-04-30
FR2361359A1 (fr)	1978-03-10
CH595360A5 (sv)	1978-02-15
FR2361328B1 (sv)	1979-07-13
CH605864A5 (sv)	1978-10-13
SE424325B (sv)	1982-07-12
SE435713B (sv)	1984-10-15
FR2361359B1 (sv)	1979-07-20
BG25991A3 (sv)	1979-01-12
YU282474A (en)	1982-02-28
PH11022A (en)	1977-10-25
BE821406A (fr)	1975-04-23
JPS5077364A (sv)	1975-06-24
AU7454774A (en)	1976-04-29
AR213086A1 (es)	1978-12-15
AT341520B (de)	1978-02-10
GB1488003A (en)	1977-10-05
ES431247A1 (es)	1977-02-16
IL45880A (en)	1979-09-30
IE40078B1 (en)	1979-03-14
NL7413848A (nl)	1975-04-25
IL45880A0 (en)	1974-12-31
HU171613B (hu)	1978-02-28
ES449655A1 (es)	1977-07-01
DE2450053A1 (de)	1975-04-24
SE424324B (sv)	1982-07-12
SE7710600L (sv)	1977-09-21
ES449654A1 (es)	1977-07-01
IL52179A0 (en)	1977-07-31
NZ175780A (en)	1978-04-03
SE7710599L (sv)	1977-09-21
DD116830A5 (sv)	1975-12-12
SU608476A3 (ru)	1978-05-25
JPS5912671B2 (ja)	1984-03-24
FR2361328A1 (fr)	1978-03-10
IL52180A0 (en)	1977-07-31
AU2880177A (en)	1979-03-15
AR221321A1 (es)	1981-01-30

Publication	Publication Date	Title
AR209755A1 (es)	1977-05-31	Nuevos compuestos derivados de la 2-hidroxi-c1-4-alquil sustituido benzofenoxima,utiles como productos intermediarios,que son terapeuticamente inactivos y particularmente apropiados para la preparacion de los correspondientes derivados benzisoxozolicos biologicamente activos
AR201880A1 (es)	1975-04-24	Procedimiento para la preparacion de nuevos derivados de 2-benzamido-5-nitrotiazol
AR213608A1 (es)	1979-02-28	Procedimiento para preparar compuestos derivados de 1a-hidroxi vitamina d
AR203878A1 (es)	1975-10-31	Procedimiento para la elaboracion de compuestos del 1-piraziniloxi 2-hidroxi-3-aminopropano
AR205129A1 (es)	1976-04-05	Procedimiento para preparar nuevos derivados de chalcona
MX152550A (es)	1985-08-23	Procedimiento para la preparacion de derivados de fenilnonatetraenos substituidos
AR205249A1 (es)	1976-04-21	Procedimiento para la sintesis de 1,2 - benzo - tiazin - 3 - carboxamidas
AR210725A1 (es)	1977-09-15	Procedimiento para la preparacion de derivados de dibenzoxepina
AR203222A1 (es)	1975-08-22	Procedimiento para la preparacion de compuestos arilacetileno
AR205619A1 (es)	1976-05-21	Procedimiento para la elaboracion de nuevos derivados (2-benzo-furanil)-piperidina
AR203188A1 (es)	1975-08-22	Procedimiento para la preparacion de derivados de tienotriazolodiacepina
AR203653A1 (es)	1975-09-30	Procedimiento para la obtencion de derivados de 3,4-dihidro-2h-naftalinona-(1)-5-oxi-propil-piperazina
AR203126A1 (es)	1975-08-14	Procedimiento para la obtencion de derivados de benzofenona
NO791507L (no)	1975-03-05	Forbindelser for anvendelse som mellomprodukter for fremstilling av terapeutisk virksomme 4-aminoamfetamin-derivater
AR201343A1 (es)	1975-02-28	Procedimiento para la preparacion de compuestos de quinoxalindiona sustituidos
BR7401013D0 (pt)	1974-11-05	Processo para obtencao de novos derivados de carbalcoxitioureidobenzeno
IT1021600B (it)	1978-02-20	Procedimento per la produzione di paradietil benzene
AR207450A1 (es)	1976-10-08	Procedimiento para la produccion de derivados de 4-fenilsulfonil-metil-prehidroindan-5-onas
AR203196A1 (es)	1975-08-22	Procedimiento para la preparacion de derivados de imidazol-5-carboxamidoxima
AR200441A1 (es)	1974-11-08	Procedimiento para la obtencion de nuevos derivados de alfa-l-arabinosido de digitoxigenina
BR7410247A (pt)	1976-06-29	Processo para preparacao de novos derivados triiodados do benzeno
AR205800A1 (es)	1976-06-07	Procedimiento para la preparacion de nuevos derivados de 3,4-difenil-imidazolina
AR206652A1 (es)	1976-08-06	Procedimiento para preparar nuevos derivados de n-amino-alquil-2-aminoindano
AR209616A1 (es)	1977-05-13	Procedimiento para la preparacion de derivados de 17alpha-aciloxi-d-homo-pregn-4-eno-3,20-diona
AR202410A1 (es)	1975-06-06	Procedimiento para la sintesis de 2,6-dehidroxicineol