JPS57154174A - Manufacture of benzoxazole derivative - Google Patents

Manufacture of benzoxazole derivative

Info

Publication number: JPS57154174A
Authority: JP; Japan
Prior art keywords: manufacture; benzoxazole derivative; benzoxazole; derivative
Prior art date: 1973-10-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP56169949A

Other languages

English (en)

Other versions

JPS636066B2 (ja

Inventor

Kurisutofuaa Saundaazu Jiyon

Robaato Nigeru Uiriamu Uiriamu

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Lilly Industries Ltd

Original Assignee

Lilly Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-10-23

Filing date

1981-10-23

Publication date

1982-09-22

1981-10-23 Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd

1982-09-22 Publication of JPS57154174A publication Critical patent/JPS57154174A/ja

1988-02-08 Publication of JPS636066B2 publication Critical patent/JPS636066B2/ja

Status Granted legal-status Critical Current

Links

BCMCBBGGLRIHSE-UHFFFAOYSA-N 1,3-benzoxazole Chemical class C1=CC=C2OC=NC2=C1 BCMCBBGGLRIHSE-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D263/57—Aryl or substituted aryl radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Rheumatology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

JP56169949A 1973-10-23 1981-10-23 Manufacture of benzoxazole derivative Granted JPS57154174A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB49259/73A GB1488003A (en)	1973-10-23	1973-10-23	1,2-benzisoxazole derivatives processes for their preparation and their use as pharmaceuticals

Publications (2)

Publication Number	Publication Date
JPS57154174A true JPS57154174A (en)	1982-09-22
JPS636066B2 JPS636066B2 (ja)	1988-02-08

Family

ID=10451720

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
JP49122354A Expired JPS5912671B2 (ja)	1973-10-23	1974-10-23	イソオキサゾ−ル誘導体の製造法
JP56169949A Granted JPS57154174A (en)	1973-10-23	1981-10-23	Manufacture of benzoxazole derivative

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
JP49122354A Expired JPS5912671B2 (ja)	1973-10-23	1974-10-23	イソオキサゾ−ル誘導体の製造法

Country Status (27)

Country	Link
US (1)	US3951999A (ja)
JP (2)	JPS5912671B2 (ja)
AR (3)	AR209755A1 (ja)
AT (1)	AT341520B (ja)
AU (1)	AU510909B2 (ja)
BE (1)	BE821406A (ja)
BG (2)	BG25991A3 (ja)
CA (1)	CA1042005A (ja)
CH (2)	CH605864A5 (ja)
CS (1)	CS189671B2 (ja)
DD (1)	DD116830A5 (ja)
DE (1)	DE2450053A1 (ja)
DK (1)	DK552674A (ja)
ES (3)	ES431247A1 (ja)
FR (3)	FR2248041B1 (ja)
GB (1)	GB1488003A (ja)
HU (1)	HU171613B (ja)
IE (1)	IE40078B1 (ja)
IL (3)	IL45880A (ja)
NL (1)	NL7413848A (ja)
NZ (1)	NZ175780A (ja)
PH (1)	PH11022A (ja)
RO (2)	RO74031A (ja)
SE (3)	SE424324B (ja)
SU (3)	SU604491A3 (ja)
YU (1)	YU282474A (ja)
ZA (1)	ZA746594B (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1590587A (en) *	1977-06-28	1981-06-03	Lilly Industries Ltd	Benoxaprofen
US4673746A (en) *	1978-10-06	1987-06-16	Hoechst-Roussel Pharmaceuticals, Inc.	1,2-benzisoxazoloxyacetic acids and related compounds
US4728662A (en) *	1977-11-21	1988-03-01	Hoechst-Roussel Pharmaceuticals Inc.	1,2-benzisoxazoloxyacetic acids and related compounds
NZ189705A (en) *	1978-03-01	1981-07-13	Boots Co Ltd	Benzophenone-hydrazone derivatives and pesticidal compositions intermediates
US4337261A (en) *	1980-07-28	1982-06-29	Hoechst-Roussel Pharmaceuticals Inc.	(1,2-Benzisoxazol)phenoxyacetic acids as diuretics
US4396770A (en) *	1982-04-09	1983-08-02	Hoechst-Roussel Pharmaceuticals Inc.	1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-phenylpiperidines
US4894461A (en) *	1981-04-27	1990-01-16	Hoechst-Roussel Pharmaceuticals, Inc.	3-(γ-chloropropyl)-6-fluoro-1,2-benzisoxazole
US4536578A (en) *	1982-04-09	1985-08-20	Hoechst-Roussel Pharmaceuticals Inc.	1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines
US4609658A (en) *	1982-04-09	1986-09-02	Hoechst-Roussel Pharmaceuticals Inc.	1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted) piperazines useful for reducing blood pressure
US4610988A (en) *	1982-04-09	1986-09-09	Hoechst-Roussel Pharmaceuticals Inc.	1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines useful for alleviating pain
US4374245A (en) *	1982-04-09	1983-02-15	Hoechst-Roussel Pharmaceuticals Inc.	8-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
US4458075A (en) *	1982-04-09	1984-07-03	Hoechst-Roussel Pharmaceuticals Inc.	6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles
US4390544A (en) *	1982-04-09	1983-06-28	Hoechst-Roussel Pharmaceuticals Inc.	{1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl}p
US4420485A (en) *	1982-09-29	1983-12-13	Hoechst-Roussel Pharmaceuticals Inc.	1'-[3-(1,2-Benzisoxazol-3-yl) proply]spiro[benzofuran-2(3H),3' or 4'-piperidines or 3'-pyrrolidines]
FR2540107B1 (fr) *	1983-01-28	1986-10-17	Inst Rech Chim Biolog	Nouveaux derives d'halogenobenzophenone-oxime, utilisation en therapeutique et procede de preparation
FI92189C (fi) *	1986-03-17	1994-10-10	Eisai Co Ltd	Menetelmä lääkeaineina käyttökelpoisen difenyylimetaanijohdannaisen valmistamiseksi
US4898874A (en) *	1986-09-15	1990-02-06	A. H. Robins Company, Inc.	Acetic acid derivatives of 3-aryl-2,1-benzisoxazole and esters and amides thereof
JPH037961U (ja) *	1989-06-14	1991-01-25
US5114960A (en) *	1989-07-20	1992-05-19	Hoffmann-La Roche Inc.	Substituted isoxazole derivatives
US8518980B2 (en) *	2006-02-10	2013-08-27	Summit Corporation Plc	Treatment of Duchenne muscular dystrophy
EP2755961A1 (en) *	2011-09-16	2014-07-23	Pfizer Inc	Solid forms of a transthyretin dissociation inhibitor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH1093669A4 (ja) *	1969-07-17	1971-02-15
FR2093173A5 (en) *	1970-06-04	1972-01-28	Gen Mills Inc	Substituted 2-hydroxybenzophenoximes for - copper extraction

1973
- 1973-10-23 GB GB49259/73A patent/GB1488003A/en not_active Expired
1974
- 1974-10-16 ZA ZA00746594A patent/ZA746594B/xx unknown
- 1974-10-16 US US05/515,131 patent/US3951999A/en not_active Expired - Lifetime
- 1974-10-18 IL IL45880A patent/IL45880A/xx unknown
- 1974-10-21 SE SE7413237A patent/SE424324B/xx unknown
- 1974-10-21 CH CH566077A patent/CH605864A5/xx not_active IP Right Cessation
- 1974-10-21 CH CH1404174A patent/CH595360A5/xx not_active IP Right Cessation
- 1974-10-22 RO RO7480288A patent/RO74031A/ro unknown
- 1974-10-22 DE DE19742450053 patent/DE2450053A1/de not_active Withdrawn
- 1974-10-22 SU SU742091795A patent/SU604491A3/ru active
- 1974-10-22 IE IE2167/74A patent/IE40078B1/xx unknown
- 1974-10-22 DK DK552674A patent/DK552674A/da not_active Application Discontinuation
- 1974-10-22 YU YU02824/74A patent/YU282474A/xx unknown
- 1974-10-22 ES ES431247A patent/ES431247A1/es not_active Expired
- 1974-10-22 RO RO7499777A patent/RO78465A/ro unknown
- 1974-10-22 CA CA212,030A patent/CA1042005A/en not_active Expired
- 1974-10-22 CS CS747227A patent/CS189671B2/cs unknown
- 1974-10-23 BG BG7428023A patent/BG25991A3/xx unknown
- 1974-10-23 AR AR256197A patent/AR209755A1/es active
- 1974-10-23 NL NL7413848A patent/NL7413848A/xx not_active Application Discontinuation
- 1974-10-23 NZ NZ175780A patent/NZ175780A/xx unknown
- 1974-10-23 DD DD181858A patent/DD116830A5/xx unknown
- 1974-10-23 JP JP49122354A patent/JPS5912671B2/ja not_active Expired
- 1974-10-23 FR FR7435535A patent/FR2248041B1/fr not_active Expired
- 1974-10-23 AT AT852374A patent/AT341520B/de not_active IP Right Cessation
- 1974-10-23 PH PH16443A patent/PH11022A/en unknown
- 1974-10-23 HU HU74LI00000266A patent/HU171613B/hu unknown
- 1974-10-23 BG BG7432026A patent/BG26531A4/xx unknown
- 1974-10-23 BE BE6044795A patent/BE821406A/xx not_active IP Right Cessation
1975
- 1975-12-29 AR AR261777A patent/AR213086A1/es active
- 1975-12-29 AR AR261776A patent/AR221321A1/es active
1976
- 1976-01-27 SU SU762315111A patent/SU608476A3/ru active
- 1976-01-28 SU SU762317502A patent/SU795459A3/ru active
- 1976-07-07 ES ES449655A patent/ES449655A1/es not_active Expired
- 1976-07-07 ES ES449654A patent/ES449654A1/es not_active Expired
1977
- 1977-03-18 FR FR7708208A patent/FR2361359A1/fr active Granted
- 1977-05-27 IL IL52179A patent/IL52179A0/xx unknown
- 1977-05-27 IL IL52180A patent/IL52180A0/xx unknown
- 1977-09-14 FR FR7727742A patent/FR2361328A1/fr active Granted
- 1977-09-14 AU AU28801/77A patent/AU510909B2/en not_active Expired
- 1977-09-21 SE SE7710599A patent/SE424325B/xx unknown
- 1977-09-21 SE SE7710600A patent/SE435713B/xx unknown
1981
- 1981-10-23 JP JP56169949A patent/JPS57154174A/ja active Granted

Also Published As

Publication number	Publication date
CA1042005A (en)	1978-11-07
US3951999A (en)	1976-04-20
DK552674A (ja)	1975-06-16
RO78465A (ro)	1982-02-26
BG26531A4 (ja)	1979-04-12
JPS636066B2 (ja)	1988-02-08
ATA852374A (de)	1977-06-15
SU604491A3 (ru)	1978-04-25
AU510909B2 (en)	1980-07-17
RO74031A (ro)	1982-02-01
FR2248041B1 (ja)	1978-09-08
SE7413237L (ja)	1975-04-24
IE40078L (en)	1975-04-23
SU795459A3 (ru)	1981-01-07
FR2248041A1 (ja)	1975-05-16
ZA746594B (en)	1976-06-30
CS189671B2 (en)	1979-04-30
FR2361359A1 (fr)	1978-03-10
CH595360A5 (ja)	1978-02-15
FR2361328B1 (ja)	1979-07-13
CH605864A5 (ja)	1978-10-13
SE424325B (sv)	1982-07-12
SE435713B (sv)	1984-10-15
FR2361359B1 (ja)	1979-07-20
BG25991A3 (ja)	1979-01-12
YU282474A (en)	1982-02-28
PH11022A (en)	1977-10-25
BE821406A (fr)	1975-04-23
JPS5077364A (ja)	1975-06-24
AU7454774A (en)	1976-04-29
AR213086A1 (es)	1978-12-15
AT341520B (de)	1978-02-10
AR209755A1 (es)	1977-05-31
GB1488003A (en)	1977-10-05
ES431247A1 (es)	1977-02-16
IL45880A (en)	1979-09-30
IE40078B1 (en)	1979-03-14
NL7413848A (nl)	1975-04-25
IL45880A0 (en)	1974-12-31
HU171613B (hu)	1978-02-28
ES449655A1 (es)	1977-07-01
DE2450053A1 (de)	1975-04-24
SE424324B (sv)	1982-07-12
SE7710600L (sv)	1977-09-21
ES449654A1 (es)	1977-07-01
IL52179A0 (en)	1977-07-31
NZ175780A (en)	1978-04-03
SE7710599L (sv)	1977-09-21
DD116830A5 (ja)	1975-12-12
SU608476A3 (ru)	1978-05-25
JPS5912671B2 (ja)	1984-03-24
FR2361328A1 (fr)	1978-03-10
IL52180A0 (en)	1977-07-31
AU2880177A (en)	1979-03-15
AR221321A1 (es)	1981-01-30

Publication	Publication Date	Title
ZA744409B (en)	1975-07-30	New derivatives of 2-benzamido-5-nitro-thiazoles
JPS57154174A (en)	1982-09-22	Manufacture of benzoxazole derivative
GR60708B (en)	1978-07-24	Preparation process of 2-acyl-4-oxo pyrazino-isoquinoline derivatives
JPS5536479A (en)	1980-03-14	Manufacture of aminoosaccharose compound
SE7808959L (sv)	1978-08-24	Forfarande for framstellning av dylenoxid
CS181861B1 (en)	1978-03-31	Mode of production of 7-hydroxy-5-methylisoflavon derivatives
JPS54138583A (en)	1979-10-27	Manufacture of diisubstituted pirerazines
JPS56138192A (en)	1981-10-28	Manufacture of 3-halocephalosporins
IL52719A0 (en)	1977-10-31	Novel oxazole derivatives
JPS5452002A (en)	1979-04-24	Manufacture of partricin derivative
FI55335B (fi)	1979-03-30	Foerfarande foer framstaellning av terapeutiskt anvaendbara 7-fluor-substituerade fenotiaziner
JPS5695159A (en)	1981-08-01	Manufacture of amidinourea compound
JPS55153766A (en)	1980-11-29	Manufacture of 99substituted 33aminocarbazole derivative
ZA745339B (en)	1975-08-27	New derivatives of 2-phenoxyacetamido-5-nitro-thiazole
JPS56164163A (en)	1981-12-17	Manufacture of 2-hydrocarbylthioaldoxime
PH17271A (en)	1984-07-03	Production of polyiminoalanes
JPS56138194A (en)	1981-10-28	Manufacture of 3-halocephalosporins
GB1405861A (en)	1975-09-10	Manufacture of convectionery
JPS56103155A (en)	1981-08-18	Manufacture of amidinourea compound
JPS57203021A (en)	1982-12-13	Manufacture of cyclobutene derivative
RO69264A (ro)	1982-04-12	Procedeu pentru prepararea alfa-amino-alcoolilor
GB1407933A (en)	1975-10-01	Sulphenylation of n-arylheterocyclic compounds
JPS5649326A (en)	1981-05-02	Manufacture of mmdichlorobenzene
ZA745927B (en)	1975-10-29	New derivatives of cyclopropylphenylprrolidnie
AU7666474A (en)	1976-06-24	Derivatives of 1-phenoxy-3-aminopropan-2-/u