AR124856A2 - Proceso para preparar un compuesto intermediario para la síntesis de compuestos de (ciclopentil[d]pirimidin-4-il)piperazina - Google Patents
Proceso para preparar un compuesto intermediario para la síntesis de compuestos de (ciclopentil[d]pirimidin-4-il)piperazinaInfo
- Publication number
- AR124856A2 AR124856A2 ARP220100275A ARP220100275A AR124856A2 AR 124856 A2 AR124856 A2 AR 124856A2 AR P220100275 A ARP220100275 A AR P220100275A AR P220100275 A ARP220100275 A AR P220100275A AR 124856 A2 AR124856 A2 AR 124856A2
- Authority
- AR
- Argentina
- Prior art keywords
- pyrimidin
- synthesis
- cyclopentyl
- preparing
- intermediate compound
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/32—Separation; Purification; Stabilisation; Use of additives
- C07C253/34—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/19—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton
- C07C255/22—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton containing cyano groups and at least two carboxyl groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/05—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in nitriles (3.5.5)
- C12Y305/05001—Nitrilase (3.5.5.1)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
La presente descripción se relaciona con un proceso para preparar un compuesto intermediario para la síntesis de compuestos de (ciclopentil[d]pirimidin-4-il)piperazina, y más particularmente para la síntesis de (R)-4-(5-metil-7-oxo-6,7-dihidro-5H-ciclopenta[d]pirimidin-4-il)piperazina y derivados N-protegidos de los mismos, los cuales pueden usarse como un intermediario en la síntesis de Ipatasertib (es decir, (S)-2-(4-clorofenil)-1-(4-((5R,7R)-7-hidroxi-5-metil-6,7-dihidro-5H-ciclopenta[d]pirimidin-4-il)piperazin-1-il)-3-(isopropilamino)-propan-1-ona).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462055893P | 2014-09-26 | 2014-09-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR124856A2 true AR124856A2 (es) | 2023-05-10 |
Family
ID=54337353
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP150103093A AR102088A1 (es) | 2014-09-26 | 2015-09-25 | Procesos para preparar compuestos de (ciclopentil[d]pirimidin-4-il)piperazina |
ARP220100275A AR124856A2 (es) | 2014-09-26 | 2022-02-11 | Proceso para preparar un compuesto intermediario para la síntesis de compuestos de (ciclopentil[d]pirimidin-4-il)piperazina |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP150103093A AR102088A1 (es) | 2014-09-26 | 2015-09-25 | Procesos para preparar compuestos de (ciclopentil[d]pirimidin-4-il)piperazina |
Country Status (21)
Country | Link |
---|---|
US (2) | US10457648B2 (es) |
EP (2) | EP3626710B1 (es) |
JP (3) | JP6676043B2 (es) |
KR (1) | KR102513869B1 (es) |
CN (2) | CN112062727B (es) |
AR (2) | AR102088A1 (es) |
AU (2) | AU2015320510B2 (es) |
BR (1) | BR112017005931B1 (es) |
CA (2) | CA3190507A1 (es) |
ES (1) | ES2749100T3 (es) |
HR (1) | HRP20191943T1 (es) |
IL (2) | IL251313B (es) |
MA (1) | MA51165A (es) |
MX (2) | MX368298B (es) |
MY (1) | MY188699A (es) |
PL (1) | PL3197875T3 (es) |
RU (2) | RU2732404C2 (es) |
SG (2) | SG11201702324QA (es) |
SI (1) | SI3197875T1 (es) |
WO (1) | WO2016049414A1 (es) |
ZA (1) | ZA201702769B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2702355C1 (ru) | 2013-11-15 | 2019-10-08 | Ф. Хоффманн-Ля Рош Аг | Способ получения пиримидинилциклопентановых соединений |
WO2016049414A1 (en) * | 2014-09-26 | 2016-03-31 | F. Hoffmann-La Roche Ag | PROCESSES FOR PREPARING (CYCLOPENTYL[d]PYRIMIDIN-4-YL)PIPERAZINE COMPOUNDS |
WO2021254920A1 (en) * | 2020-06-16 | 2021-12-23 | F. Hoffmann-La Roche Ag | Process for making hydroxylated cyclopentylpyrimidine compounds |
CN112359078A (zh) * | 2021-01-12 | 2021-02-12 | 凯莱英生命科学技术(天津)有限公司 | 异丁酸酯类化合物的手性拆分方法 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1045764A (en) | 1912-04-30 | 1912-11-26 | Samuel Allen Guiberson Jr | Casing-elevator. |
GB9400889D0 (en) | 1994-01-18 | 1994-03-16 | Sandoz Ltd | Novel compounds |
DK1678182T3 (da) * | 2003-10-28 | 2007-06-04 | Schering Corp | Fremgangsmåde til fremstilling af substituerede 5-amino-pyrazolo[4,3-E]-1,2,4-triazolo-[1,5-C]pyrimidiner |
US20080004269A1 (en) | 2004-11-04 | 2008-01-03 | Yuelian Xu | Pyrazolylmethy Heteroaryl Derivatives |
TW200630363A (en) * | 2004-11-10 | 2006-09-01 | Synta Pharmaceuticals Corp | Process for preparing trisubstituted pyrimidine compounds |
UA95641C2 (en) * | 2006-07-06 | 2011-08-25 | Эррей Биофарма Инк. | Hydroxylated cyclopenta [d] pyrimidines as akt protein kinase inhibitors |
US8063050B2 (en) | 2006-07-06 | 2011-11-22 | Array Biopharma Inc. | Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
WO2010002954A1 (en) * | 2008-07-02 | 2010-01-07 | Wyeth | (2-aryl-7h-pyrrolo[2,3-d]pyrimidin-4-yl)morpholine compounds, their use as mtor kinase and pi3 kinase inhibitors, and their syntheses |
US8703581B2 (en) | 2011-06-15 | 2014-04-22 | Applied Materials, Inc. | Water soluble mask for substrate dicing by laser and plasma etch |
DE102011080205A1 (de) | 2011-08-01 | 2013-02-07 | Bayerische Motoren Werke Aktiengesellschaft | Verfahren zur Herstellung faserverstärkter keramischer Formkörper |
WO2013068785A1 (en) * | 2011-11-09 | 2013-05-16 | Actelion Pharmaceuticals Ltd | Indanone and indandione derivatives and heterocyclic analogs |
CA2873658C (en) * | 2012-05-17 | 2021-01-26 | Genentech, Inc. | Process for making amino acid compounds |
RU2014151017A (ru) | 2012-05-17 | 2016-07-10 | Аррэй Байофарма Инк. | Способ получения гидроксилированных циклопентилпиримидинов |
CA2873661C (en) | 2012-05-17 | 2020-07-21 | Genentech, Inc. | Process of making hydroxylated cyclopentapyrimidine compounds and salts thereof |
RU2643811C2 (ru) | 2012-05-17 | 2018-02-06 | Аррэй Байофарма Инк. | Способ получения гидроксилированных циклопентилпиримидиновых соединений |
RU2702355C1 (ru) | 2013-11-15 | 2019-10-08 | Ф. Хоффманн-Ля Рош Аг | Способ получения пиримидинилциклопентановых соединений |
US9437599B2 (en) * | 2014-08-12 | 2016-09-06 | Kabushiki Kaisha Toshiba | Nonvolatile semiconductor memory device and method of manufacturing the same |
WO2016049414A1 (en) * | 2014-09-26 | 2016-03-31 | F. Hoffmann-La Roche Ag | PROCESSES FOR PREPARING (CYCLOPENTYL[d]PYRIMIDIN-4-YL)PIPERAZINE COMPOUNDS |
KR102256602B1 (ko) | 2017-12-14 | 2021-05-26 | 주식회사 엘지에너지솔루션 | 전압 측정 장치 및 방법 |
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2015
- 2015-09-25 WO PCT/US2015/052143 patent/WO2016049414A1/en active Application Filing
- 2015-09-25 PL PL15782120T patent/PL3197875T3/pl unknown
- 2015-09-25 BR BR112017005931-2A patent/BR112017005931B1/pt active IP Right Grant
- 2015-09-25 MY MYPI2017000443A patent/MY188699A/en unknown
- 2015-09-25 SG SG11201702324QA patent/SG11201702324QA/en unknown
- 2015-09-25 RU RU2020101483A patent/RU2732404C2/ru active
- 2015-09-25 JP JP2017516092A patent/JP6676043B2/ja active Active
- 2015-09-25 KR KR1020177011162A patent/KR102513869B1/ko active IP Right Grant
- 2015-09-25 AR ARP150103093A patent/AR102088A1/es active IP Right Grant
- 2015-09-25 CN CN202010779430.3A patent/CN112062727B/zh active Active
- 2015-09-25 CN CN201580063946.5A patent/CN107001287B/zh active Active
- 2015-09-25 CA CA3190507A patent/CA3190507A1/en active Pending
- 2015-09-25 ES ES15782120T patent/ES2749100T3/es active Active
- 2015-09-25 EP EP19191353.2A patent/EP3626710B1/en active Active
- 2015-09-25 SG SG10201806450SA patent/SG10201806450SA/en unknown
- 2015-09-25 RU RU2017114035A patent/RU2712224C2/ru active
- 2015-09-25 EP EP15782120.8A patent/EP3197875B1/en active Active
- 2015-09-25 AU AU2015320510A patent/AU2015320510B2/en active Active
- 2015-09-25 SI SI201530985T patent/SI3197875T1/sl unknown
- 2015-09-25 US US15/514,188 patent/US10457648B2/en active Active
- 2015-09-25 MA MA051165A patent/MA51165A/fr unknown
- 2015-09-25 MX MX2017003791A patent/MX368298B/es active IP Right Grant
- 2015-09-25 CA CA2962901A patent/CA2962901A1/en active Pending
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2017
- 2017-03-21 IL IL251313A patent/IL251313B/en active IP Right Grant
- 2017-03-23 MX MX2019011513A patent/MX2019011513A/es unknown
- 2017-04-19 ZA ZA2017/02769A patent/ZA201702769B/en unknown
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2019
- 2019-07-01 IL IL267756A patent/IL267756B/en active IP Right Grant
- 2019-09-18 US US16/574,933 patent/US10870626B2/en active Active
- 2019-10-23 AU AU2019253849A patent/AU2019253849B2/en active Active
- 2019-10-24 HR HRP20191943TT patent/HRP20191943T1/hr unknown
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2020
- 2020-01-27 JP JP2020010838A patent/JP6926254B2/ja active Active
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2021
- 2021-08-04 JP JP2021127998A patent/JP2021169535A/ja not_active Withdrawn
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2022
- 2022-02-11 AR ARP220100275A patent/AR124856A2/es unknown
Also Published As
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