AR095462A1 - Composiciones y métodos para la producción y administración de arn - Google Patents
Composiciones y métodos para la producción y administración de arnInfo
- Publication number
- AR095462A1 AR095462A1 ARP140101064A ARP140101064A AR095462A1 AR 095462 A1 AR095462 A1 AR 095462A1 AR P140101064 A ARP140101064 A AR P140101064A AR P140101064 A ARP140101064 A AR P140101064A AR 095462 A1 AR095462 A1 AR 095462A1
- Authority
- AR
- Argentina
- Prior art keywords
- compositions
- methods
- rna
- dsrna
- analysis
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/60—Isolated nucleic acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H3/00—Processes for modifying phenotypes, e.g. symbiosis with bacteria
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/72—Expression systems using regulatory sequences derived from the lac-operon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
- C12N2310/531—Stem-loop; Hairpin
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Dentistry (AREA)
- Virology (AREA)
- Agronomy & Crop Science (AREA)
- Botany (AREA)
- Developmental Biology & Embryology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Insects & Arthropods (AREA)
Abstract
Se proporcionan composiciones y métodos para producir y administrar eficazmente ARN de doble cadena (ARNdc). Se describen construcciones de vectores útiles para la expresión de ARNdc in vitro e in vivo. También se describen sistemas de expresión celular para la producción eficaz y rentable de ARNdc en células vivas y métodos y composiciones para proporcionar el ARNdc expresado a organismos diana. Las composiciones y métodos descritos se pueden usar para producir moléculas de ARN para análisis u otros usos, y para amplificar secuencias de ARN para análisis. Célula; método para controlar una infestación; método para inhibir; terminador.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361793506P | 2013-03-15 | 2013-03-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR095462A1 true AR095462A1 (es) | 2015-10-21 |
Family
ID=50928237
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP140101064A AR095462A1 (es) | 2013-03-15 | 2014-03-14 | Composiciones y métodos para la producción y administración de arn |
Country Status (14)
Country | Link |
---|---|
US (7) | US9445603B2 (es) |
EP (2) | EP2970990B1 (es) |
JP (2) | JP6522579B2 (es) |
KR (3) | KR102530901B1 (es) |
CN (2) | CN110229815B (es) |
AR (1) | AR095462A1 (es) |
AU (1) | AU2014233711B2 (es) |
BR (1) | BR112015023424A2 (es) |
CA (1) | CA2905961C (es) |
ES (2) | ES2691803T3 (es) |
MX (2) | MX358744B (es) |
UA (1) | UA120349C2 (es) |
WO (1) | WO2014151581A1 (es) |
ZA (1) | ZA201506682B (es) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8097712B2 (en) | 2007-11-07 | 2012-01-17 | Beelogics Inc. | Compositions for conferring tolerance to viral disease in social insects, and the use thereof |
US8962584B2 (en) | 2009-10-14 | 2015-02-24 | Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. | Compositions for controlling Varroa mites in bees |
US20130047297A1 (en) | 2010-03-08 | 2013-02-21 | Robert D. Sammons | Polynucleotide molecules for gene regulation in plants |
EP3219796B1 (en) | 2010-08-31 | 2020-10-07 | GreenLight Biosciences, Inc. | Methods for control of flux in metabolic pathways through protease manipulation |
US10760086B2 (en) | 2011-09-13 | 2020-09-01 | Monsanto Technology Llc | Methods and compositions for weed control |
CA2848689A1 (en) | 2011-09-13 | 2013-03-21 | Monsanto Technology Llc | Methods and compositions for weed control targeting pds |
US10829828B2 (en) | 2011-09-13 | 2020-11-10 | Monsanto Technology Llc | Methods and compositions for weed control |
US10806146B2 (en) | 2011-09-13 | 2020-10-20 | Monsanto Technology Llc | Methods and compositions for weed control |
IN2014MN02404A (es) | 2012-05-24 | 2015-08-21 | Seeds Ltd Ab | |
US10683505B2 (en) | 2013-01-01 | 2020-06-16 | Monsanto Technology Llc | Methods of introducing dsRNA to plant seeds for modulating gene expression |
CN105358695B (zh) | 2013-01-01 | 2019-07-12 | A.B.种子有限公司 | 将dsRNA引入植物种子以调节基因表达的方法 |
EP2967082A4 (en) | 2013-03-13 | 2016-11-02 | Monsanto Technology Llc | METHOD AND COMPOSITIONS FOR WEED CONTROL |
CA2905027A1 (en) | 2013-03-13 | 2014-10-09 | Monsanto Technology Llc | Methods and compositions for weed control |
US10568328B2 (en) | 2013-03-15 | 2020-02-25 | Monsanto Technology Llc | Methods and compositions for weed control |
ES2691803T3 (es) | 2013-03-15 | 2018-11-28 | Monsanto Technology Llc | Composiciones y procedimientos para la producción y administración de ARN |
MX359191B (es) | 2013-07-19 | 2018-09-18 | Monsanto Technology Llc | Composiciones y métodos para controlar leptinotarsa. |
US9850496B2 (en) | 2013-07-19 | 2017-12-26 | Monsanto Technology Llc | Compositions and methods for controlling Leptinotarsa |
US9688977B2 (en) | 2013-08-05 | 2017-06-27 | Greenlight Biosciences, Inc. | Engineered phosphoglucose isomerase proteins with a protease cleavage site |
MX2016005778A (es) | 2013-11-04 | 2016-12-20 | Monsanto Technology Llc | Composiciones y metodos para controlar infestaciones de plagas y parasitos de los artropodos. |
UA119253C2 (uk) | 2013-12-10 | 2019-05-27 | Біолоджикс, Інк. | Спосіб боротьби із вірусом у кліща varroa та у бджіл |
AU2015206585A1 (en) | 2014-01-15 | 2016-07-21 | Monsanto Technology Llc | Methods and compositions for weed control using EPSPS polynucleotides |
EP3125676A4 (en) | 2014-04-01 | 2018-02-14 | Monsanto Technology LLC | Compositions and methods for controlling insect pests |
CA2953347A1 (en) | 2014-06-23 | 2015-12-30 | Monsanto Technology Llc | Compositions and methods for regulating gene expression via rna interference |
WO2015200539A1 (en) | 2014-06-25 | 2015-12-30 | Monsanto Technology Llc | Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression |
EP3174982A4 (en) | 2014-07-29 | 2018-06-20 | Monsanto Technology LLC | Compositions and methods for controlling insect pests |
RU2723049C2 (ru) | 2015-01-22 | 2020-06-08 | Монсанто Текнолоджи Ллс | Композиции и способы борьбы с leptinotarsa |
MY193444A (en) | 2015-03-30 | 2022-10-13 | Greenlight Biosciences Inc | Cell-free production of ribonucleic acid |
UY36703A (es) | 2015-06-02 | 2016-12-30 | Monsanto Technology Llc | Composiciones y métodos para la administración de un polinucleótido en una planta |
CN108024517A (zh) | 2015-06-03 | 2018-05-11 | 孟山都技术公司 | 用于将核酸引入到植物中的方法和组合物 |
EP3322798A4 (en) | 2015-07-14 | 2019-03-06 | Transalgae Israel Ltd. | TRANSGENIC MICROALGUES AND THEIR USE AS A DELIVERY OF INTERFERENCE RNA MOLECULE DELIVERY |
CN105219796A (zh) * | 2015-09-29 | 2016-01-06 | 生工生物工程(上海)股份有限公司 | 一种转录终止子及其在基因克隆中的应用 |
AU2016335158A1 (en) * | 2015-10-05 | 2018-04-12 | Devgen Nv | Methods of preserving the biological activity of ribonucleic acids |
SG11201807478QA (en) | 2016-03-15 | 2018-09-27 | Apse Inc | Methods and compositions for increased double stranded rna production |
CR20180525A (es) | 2016-04-06 | 2019-02-14 | Greenlight Biosciences Inc | Producción de ácido ribonucleico libre de células |
KR20190100386A (ko) | 2017-01-06 | 2019-08-28 | 그린라이트 바이오사이언시스, 아이엔씨. | 당의 무세포 생산 |
WO2018134386A1 (en) | 2017-01-23 | 2018-07-26 | Novozymes A/S | Host cells and methods for producing double-stranded rna |
WO2018179834A1 (en) * | 2017-03-28 | 2018-10-04 | Ajinomoto Co., Inc. | Method for producing rna |
US20200149048A1 (en) * | 2017-05-22 | 2020-05-14 | Pebble Labs Usa Inc. | Transbiotic Regulation of Bacterial Gene Expression |
BR112020002689A2 (pt) | 2017-08-07 | 2020-08-25 | Pebble Labs Usa Inc. | sistemas e métodos para o controle de doença de necrose hepatopancreática aguda |
KR102571743B1 (ko) | 2017-10-11 | 2023-08-29 | 그린라이트 바이오사이언시스, 아이엔씨. | 뉴클레오시드 트리포스페이트 및 리보핵산 생산을 위한 방법 및 조성물 |
CN108165559B (zh) * | 2017-11-29 | 2021-06-18 | 昆明理工大学 | 一种c2h2型转录因子基因及其应用 |
JP7367667B2 (ja) * | 2018-02-20 | 2023-10-24 | 味の素株式会社 | Rnaサイレンシングを誘導する方法 |
CN108570434A (zh) * | 2018-05-10 | 2018-09-25 | 苏州博悦曼环保科技有限公司 | 高效降解餐厨垃圾的复合菌剂及其制造方法 |
CN113943764B (zh) * | 2021-12-20 | 2022-03-04 | 中国海洋大学 | 一种制备双链rna的方法 |
CN114774456A (zh) * | 2022-04-19 | 2022-07-22 | 中国农业科学院农产品加工研究所 | 一种营养缺陷型拟轮枝镰孢菌突变体构建方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL133830A0 (en) | 1997-07-01 | 2001-04-30 | Cambia Biosystems Llc | Vertebrate tolomerase genes and proteins and uses thereof |
DE19806872A1 (de) | 1998-02-19 | 1999-08-26 | Basf Ag | Verfahren zur Herstellung von Biotin |
CN1997737B (zh) * | 2004-04-09 | 2018-11-30 | 孟山都技术有限公司 | 用于在植物中控制昆虫侵袭的组合物和方法 |
CN104357446A (zh) * | 2005-09-16 | 2015-02-18 | 德福根有限公司 | 作为昆虫控制剂的dsrna |
EP3508582B1 (en) * | 2005-09-16 | 2021-01-13 | Monsanto Technology LLC | Methods for genetic control of insect infestations in plants and compositions thereof |
US20130047297A1 (en) | 2010-03-08 | 2013-02-21 | Robert D. Sammons | Polynucleotide molecules for gene regulation in plants |
US9057057B2 (en) * | 2010-07-27 | 2015-06-16 | The Johns Hopkins University | Obligate heterodimer variants of foki cleavage domain |
US20140259204A1 (en) * | 2010-10-15 | 2014-09-11 | The University Of Queensland | Small viral rna molecules and uses thereof |
EP2530159A1 (en) * | 2011-06-03 | 2012-12-05 | Sandoz Ag | Transcription terminator sequences |
WO2012170433A1 (en) | 2011-06-08 | 2012-12-13 | Sutro Biopharma, Inc. | Multiple rna polymerase terminator cassettes for efficient transcription of discrete rna templates |
ES2691803T3 (es) * | 2013-03-15 | 2018-11-28 | Monsanto Technology Llc | Composiciones y procedimientos para la producción y administración de ARN |
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2014
- 2014-03-13 ES ES14729497.9T patent/ES2691803T3/es active Active
- 2014-03-13 KR KR1020217028907A patent/KR102530901B1/ko active IP Right Grant
- 2014-03-13 US US14/208,788 patent/US9445603B2/en active Active
- 2014-03-13 CN CN201910305702.3A patent/CN110229815B/zh active Active
- 2014-03-13 WO PCT/US2014/026036 patent/WO2014151581A1/en active Application Filing
- 2014-03-13 EP EP14729497.9A patent/EP2970990B1/en active Active
- 2014-03-13 KR KR1020157029650A patent/KR20150131310A/ko not_active IP Right Cessation
- 2014-03-13 CN CN201480024780.1A patent/CN105164265B/zh active Active
- 2014-03-13 JP JP2016502033A patent/JP6522579B2/ja active Active
- 2014-03-13 ES ES18176147T patent/ES2837575T3/es active Active
- 2014-03-13 MX MX2015013118A patent/MX358744B/es active IP Right Grant
- 2014-03-13 CA CA2905961A patent/CA2905961C/en active Active
- 2014-03-13 BR BR112015023424A patent/BR112015023424A2/pt active Search and Examination
- 2014-03-13 EP EP18176147.9A patent/EP3434777B1/en active Active
- 2014-03-13 KR KR1020237015148A patent/KR20230066486A/ko not_active Application Discontinuation
- 2014-03-13 UA UAA201510008A patent/UA120349C2/uk unknown
- 2014-03-13 AU AU2014233711A patent/AU2014233711B2/en active Active
- 2014-03-13 US US14/901,003 patent/US9814243B2/en active Active
- 2014-03-14 AR ARP140101064A patent/AR095462A1/es not_active Application Discontinuation
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2015
- 2015-09-09 ZA ZA2015/06682A patent/ZA201506682B/en unknown
- 2015-09-15 MX MX2018010529A patent/MX2018010529A/es unknown
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2016
- 2016-08-15 US US15/237,214 patent/US10070652B2/en active Active
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2017
- 2017-10-10 US US15/729,114 patent/US10334858B2/en active Active
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2018
- 2018-08-14 US US16/103,451 patent/US10757947B2/en active Active
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2019
- 2019-04-24 JP JP2019082957A patent/JP6935450B2/ja active Active
- 2019-06-07 US US16/434,854 patent/US11647753B2/en active Active
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2023
- 2023-04-12 US US18/299,295 patent/US20230232838A1/en active Pending
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