AR095462A1 - Composiciones y métodos para la producción y administración de arn - Google Patents

Composiciones y métodos para la producción y administración de arn

Info

Publication number
AR095462A1
AR095462A1 ARP140101064A ARP140101064A AR095462A1 AR 095462 A1 AR095462 A1 AR 095462A1 AR P140101064 A ARP140101064 A AR P140101064A AR P140101064 A ARP140101064 A AR P140101064A AR 095462 A1 AR095462 A1 AR 095462A1
Authority
AR
Argentina
Prior art keywords
compositions
methods
rna
dsrna
analysis
Prior art date
Application number
ARP140101064A
Other languages
English (en)
Original Assignee
Monsanto Technology Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Technology Llc filed Critical Monsanto Technology Llc
Publication of AR095462A1 publication Critical patent/AR095462A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/60Isolated nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H3/00Processes for modifying phenotypes, e.g. symbiosis with bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • C12N15/72Expression systems using regulatory sequences derived from the lac-operon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases RNAses, DNAses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/50Physical structure
    • C12N2310/53Physical structure partially self-complementary or closed
    • C12N2310/531Stem-loop; Hairpin
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Virology (AREA)
  • Agronomy & Crop Science (AREA)
  • Botany (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Insects & Arthropods (AREA)

Abstract

Se proporcionan composiciones y métodos para producir y administrar eficazmente ARN de doble cadena (ARNdc). Se describen construcciones de vectores útiles para la expresión de ARNdc in vitro e in vivo. También se describen sistemas de expresión celular para la producción eficaz y rentable de ARNdc en células vivas y métodos y composiciones para proporcionar el ARNdc expresado a organismos diana. Las composiciones y métodos descritos se pueden usar para producir moléculas de ARN para análisis u otros usos, y para amplificar secuencias de ARN para análisis. Célula; método para controlar una infestación; método para inhibir; terminador.
ARP140101064A 2013-03-15 2014-03-14 Composiciones y métodos para la producción y administración de arn AR095462A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361793506P 2013-03-15 2013-03-15

Publications (1)

Publication Number Publication Date
AR095462A1 true AR095462A1 (es) 2015-10-21

Family

ID=50928237

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP140101064A AR095462A1 (es) 2013-03-15 2014-03-14 Composiciones y métodos para la producción y administración de arn

Country Status (14)

Country Link
US (7) US9445603B2 (es)
EP (2) EP2970990B1 (es)
JP (2) JP6522579B2 (es)
KR (3) KR102530901B1 (es)
CN (2) CN110229815B (es)
AR (1) AR095462A1 (es)
AU (1) AU2014233711B2 (es)
BR (1) BR112015023424A2 (es)
CA (1) CA2905961C (es)
ES (2) ES2691803T3 (es)
MX (2) MX358744B (es)
UA (1) UA120349C2 (es)
WO (1) WO2014151581A1 (es)
ZA (1) ZA201506682B (es)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8097712B2 (en) 2007-11-07 2012-01-17 Beelogics Inc. Compositions for conferring tolerance to viral disease in social insects, and the use thereof
US8962584B2 (en) 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
US20130047297A1 (en) 2010-03-08 2013-02-21 Robert D. Sammons Polynucleotide molecules for gene regulation in plants
EP3219796B1 (en) 2010-08-31 2020-10-07 GreenLight Biosciences, Inc. Methods for control of flux in metabolic pathways through protease manipulation
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
CA2848689A1 (en) 2011-09-13 2013-03-21 Monsanto Technology Llc Methods and compositions for weed control targeting pds
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
IN2014MN02404A (es) 2012-05-24 2015-08-21 Seeds Ltd Ab
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
CN105358695B (zh) 2013-01-01 2019-07-12 A.B.种子有限公司 将dsRNA引入植物种子以调节基因表达的方法
EP2967082A4 (en) 2013-03-13 2016-11-02 Monsanto Technology Llc METHOD AND COMPOSITIONS FOR WEED CONTROL
CA2905027A1 (en) 2013-03-13 2014-10-09 Monsanto Technology Llc Methods and compositions for weed control
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
ES2691803T3 (es) 2013-03-15 2018-11-28 Monsanto Technology Llc Composiciones y procedimientos para la producción y administración de ARN
MX359191B (es) 2013-07-19 2018-09-18 Monsanto Technology Llc Composiciones y métodos para controlar leptinotarsa.
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
US9688977B2 (en) 2013-08-05 2017-06-27 Greenlight Biosciences, Inc. Engineered phosphoglucose isomerase proteins with a protease cleavage site
MX2016005778A (es) 2013-11-04 2016-12-20 Monsanto Technology Llc Composiciones y metodos para controlar infestaciones de plagas y parasitos de los artropodos.
UA119253C2 (uk) 2013-12-10 2019-05-27 Біолоджикс, Інк. Спосіб боротьби із вірусом у кліща varroa та у бджіл
AU2015206585A1 (en) 2014-01-15 2016-07-21 Monsanto Technology Llc Methods and compositions for weed control using EPSPS polynucleotides
EP3125676A4 (en) 2014-04-01 2018-02-14 Monsanto Technology LLC Compositions and methods for controlling insect pests
CA2953347A1 (en) 2014-06-23 2015-12-30 Monsanto Technology Llc Compositions and methods for regulating gene expression via rna interference
WO2015200539A1 (en) 2014-06-25 2015-12-30 Monsanto Technology Llc Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
EP3174982A4 (en) 2014-07-29 2018-06-20 Monsanto Technology LLC Compositions and methods for controlling insect pests
RU2723049C2 (ru) 2015-01-22 2020-06-08 Монсанто Текнолоджи Ллс Композиции и способы борьбы с leptinotarsa
MY193444A (en) 2015-03-30 2022-10-13 Greenlight Biosciences Inc Cell-free production of ribonucleic acid
UY36703A (es) 2015-06-02 2016-12-30 Monsanto Technology Llc Composiciones y métodos para la administración de un polinucleótido en una planta
CN108024517A (zh) 2015-06-03 2018-05-11 孟山都技术公司 用于将核酸引入到植物中的方法和组合物
EP3322798A4 (en) 2015-07-14 2019-03-06 Transalgae Israel Ltd. TRANSGENIC MICROALGUES AND THEIR USE AS A DELIVERY OF INTERFERENCE RNA MOLECULE DELIVERY
CN105219796A (zh) * 2015-09-29 2016-01-06 生工生物工程(上海)股份有限公司 一种转录终止子及其在基因克隆中的应用
AU2016335158A1 (en) * 2015-10-05 2018-04-12 Devgen Nv Methods of preserving the biological activity of ribonucleic acids
SG11201807478QA (en) 2016-03-15 2018-09-27 Apse Inc Methods and compositions for increased double stranded rna production
CR20180525A (es) 2016-04-06 2019-02-14 Greenlight Biosciences Inc Producción de ácido ribonucleico libre de células
KR20190100386A (ko) 2017-01-06 2019-08-28 그린라이트 바이오사이언시스, 아이엔씨. 당의 무세포 생산
WO2018134386A1 (en) 2017-01-23 2018-07-26 Novozymes A/S Host cells and methods for producing double-stranded rna
WO2018179834A1 (en) * 2017-03-28 2018-10-04 Ajinomoto Co., Inc. Method for producing rna
US20200149048A1 (en) * 2017-05-22 2020-05-14 Pebble Labs Usa Inc. Transbiotic Regulation of Bacterial Gene Expression
BR112020002689A2 (pt) 2017-08-07 2020-08-25 Pebble Labs Usa Inc. sistemas e métodos para o controle de doença de necrose hepatopancreática aguda
KR102571743B1 (ko) 2017-10-11 2023-08-29 그린라이트 바이오사이언시스, 아이엔씨. 뉴클레오시드 트리포스페이트 및 리보핵산 생산을 위한 방법 및 조성물
CN108165559B (zh) * 2017-11-29 2021-06-18 昆明理工大学 一种c2h2型转录因子基因及其应用
JP7367667B2 (ja) * 2018-02-20 2023-10-24 味の素株式会社 Rnaサイレンシングを誘導する方法
CN108570434A (zh) * 2018-05-10 2018-09-25 苏州博悦曼环保科技有限公司 高效降解餐厨垃圾的复合菌剂及其制造方法
CN113943764B (zh) * 2021-12-20 2022-03-04 中国海洋大学 一种制备双链rna的方法
CN114774456A (zh) * 2022-04-19 2022-07-22 中国农业科学院农产品加工研究所 一种营养缺陷型拟轮枝镰孢菌突变体构建方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL133830A0 (en) 1997-07-01 2001-04-30 Cambia Biosystems Llc Vertebrate tolomerase genes and proteins and uses thereof
DE19806872A1 (de) 1998-02-19 1999-08-26 Basf Ag Verfahren zur Herstellung von Biotin
CN1997737B (zh) * 2004-04-09 2018-11-30 孟山都技术有限公司 用于在植物中控制昆虫侵袭的组合物和方法
CN104357446A (zh) * 2005-09-16 2015-02-18 德福根有限公司 作为昆虫控制剂的dsrna
EP3508582B1 (en) * 2005-09-16 2021-01-13 Monsanto Technology LLC Methods for genetic control of insect infestations in plants and compositions thereof
US20130047297A1 (en) 2010-03-08 2013-02-21 Robert D. Sammons Polynucleotide molecules for gene regulation in plants
US9057057B2 (en) * 2010-07-27 2015-06-16 The Johns Hopkins University Obligate heterodimer variants of foki cleavage domain
US20140259204A1 (en) * 2010-10-15 2014-09-11 The University Of Queensland Small viral rna molecules and uses thereof
EP2530159A1 (en) * 2011-06-03 2012-12-05 Sandoz Ag Transcription terminator sequences
WO2012170433A1 (en) 2011-06-08 2012-12-13 Sutro Biopharma, Inc. Multiple rna polymerase terminator cassettes for efficient transcription of discrete rna templates
ES2691803T3 (es) * 2013-03-15 2018-11-28 Monsanto Technology Llc Composiciones y procedimientos para la producción y administración de ARN

Also Published As

Publication number Publication date
CA2905961C (en) 2023-04-25
WO2014151581A9 (en) 2015-12-03
AU2014233711A1 (en) 2015-10-01
JP6522579B2 (ja) 2019-05-29
MX2015013118A (es) 2016-02-09
EP2970990A1 (en) 2016-01-20
US20190000089A1 (en) 2019-01-03
US20160145630A1 (en) 2016-05-26
KR102530901B1 (ko) 2023-05-11
EP3434777B1 (en) 2020-09-23
US20180092364A1 (en) 2018-04-05
US20140271559A1 (en) 2014-09-18
AU2014233711A9 (en) 2016-06-16
ES2691803T3 (es) 2018-11-28
MX358744B (es) 2018-08-31
WO2014151581A1 (en) 2014-09-25
US9445603B2 (en) 2016-09-20
US10757947B2 (en) 2020-09-01
US20190380348A1 (en) 2019-12-19
JP2016517274A (ja) 2016-06-16
AU2014233711B2 (en) 2020-05-28
ZA201506682B (en) 2018-11-28
US11647753B2 (en) 2023-05-16
EP2970990B1 (en) 2018-07-18
KR20230066486A (ko) 2023-05-15
CN105164265A (zh) 2015-12-16
EP3434777A1 (en) 2019-01-30
US20170035056A1 (en) 2017-02-09
CN110229815B (zh) 2024-02-20
BR112015023424A2 (pt) 2017-11-28
CN110229815A (zh) 2019-09-13
CA2905961A1 (en) 2014-09-25
UA120349C2 (uk) 2019-11-25
MX2018010529A (es) 2022-01-25
KR20210116681A (ko) 2021-09-27
US9814243B2 (en) 2017-11-14
CN105164265B (zh) 2019-05-10
US20230232838A1 (en) 2023-07-27
JP2019150036A (ja) 2019-09-12
US10334858B2 (en) 2019-07-02
ES2837575T3 (es) 2021-06-30
JP6935450B2 (ja) 2021-09-15
US10070652B2 (en) 2018-09-11
KR20150131310A (ko) 2015-11-24

Similar Documents

Publication Publication Date Title
AR095462A1 (es) Composiciones y métodos para la producción y administración de arn
CL2016001553A1 (es) Medios para cultivo celular
CL2018002852A1 (es) Producción celular de ácido ribonucleico
AR080372A1 (es) Mejoramiento funcional de microorganismos para minimizar la produccion de acrilamida
AR092481A1 (es) Desempeño de ubicacion de fad2 y de las proteinas especificas correspondientes de union de ubicacion selectiva capaces de inducir rupturas selectivas
BR112017024384A2 (pt) bactérias modificadas para reduzir hiperfenilalaninemia
AR105602A1 (es) Medio de cultivo celular suplementado con taurina y métodos de utilización
EP3722438A3 (en) Method for production of moth pheromones in yeast
CL2018001577A1 (es) Anticuerpos anti-c5 y métodos de uso
EA201590488A1 (ru) Способы модификации клеток-хозяев
BR112019000693A2 (pt) composições de muc1- car e métodos para uso
BR112013018516A2 (pt) constructo de ácido nucléico para expressão de alfa-galactosidade em plantas e células de plantas
CL2019000318A1 (es) Método para producir un l-aminoácido tal como l-lisina.
CL2017002427A1 (es) Producción de ácido ribonucleico libre de células.
UY35366A (es) ?genes de toxina y métodos para su uso?.
MY182946A (en) Production of organic acids by fermentation at low ph
AR090070A1 (es) Proteinas pesticidas modificadas
AR072832A1 (es) LINEAS DE CELULAS HOSPEDANTES DE PRODUCCION MEJORADA QUE CONTIENEN CONSTRUCCIONES DE VECTORES QUE COMPRENDEN UN CASETE DE EXPRESIoN DE DHFR (ENZIMA DIHIDROFOLATO REDUCTASA).
CR20160195A (es) Composiciones y métodos para inhibir la expresión del gen alas 1
MX2015015274A (es) Ruta de ácido organico novedosa.
BR112017020513A2 (pt) método de produção de peixe para transplante, peixe para transplante, método de produção de espécie híbrida de peixe e espécie híbrida de peixe
AR083029A1 (es) Metodos y composiciones que utilizan arn interferente pequeño (arnip) para el control de nematodos en plantas
UY32488A (es) Lipasa cpo y derivados de la misma
CU20160153A7 (es) Proteína antiporter de protones/azúcar tonoplastidiarias adecuadas para incrementar la concentración de sacarosa en un órgano vegetal de almacenamiento de sacarosa
BR112013024903A2 (pt) ácido nucleico isolado, vetor, tecido vegetal, pequena molécula de ácido ribonucleico inibitória isolada, molécula de ácido ribonucleico de filamento duplo isolada, dsrna isolada, tecido vegetal transformado com a célula hospedeira, célula hospedeira, método de produção de uma planta resistente a praga, método de inibição de uma infestação de praga e método de produção de uma planta resistente a uma praga patogênica de planta

Legal Events

Date Code Title Description
FC Refusal