AR088578A1 - Sistema de administracion vaginal osmoticamente activo - Google Patents
Sistema de administracion vaginal osmoticamente activoInfo
- Publication number
- AR088578A1 AR088578A1 ARP120104055A ARP120104055A AR088578A1 AR 088578 A1 AR088578 A1 AR 088578A1 AR P120104055 A ARP120104055 A AR P120104055A AR P120104055 A ARP120104055 A AR P120104055A AR 088578 A1 AR088578 A1 AR 088578A1
- Authority
- AR
- Argentina
- Prior art keywords
- administration system
- active substances
- osmotically active
- vaginal administration
- styrene
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente se refiere al campo de los sistemas de administración de fármacos. Más particularmente, la presente se refiere a sistemas de administración intravaginal osmóticamente activos para la liberación controlada de sustancias terapéuticamente activas en la cavidad vaginal. Reivindicación 1: Un sistema de administración vaginal osmóticamente activo, cuyo cuerpo comprende: al menos un compartimiento que comprende una composición de una o más sustancias terapéuticamente activas, al menos un compartimiento, ya sea igual o diferente al que comprende la(s) sustancia(s) terapéuticamente activa(s), que comprende una composición osmótica capaz de interactuar con agua y/o fluidos biológicos acuosos para crear un gradiente de concentración contra el fluido exterior o de hincharse o expandirse para crear presión osmótica, y al menos un pasaje que se extiende desde el compartimiento que comprende la composición de una o más sustancias terapéuticamente activas hasta la superficie externa del cuerpo. Reivindicación 3: Un sistema de administración vaginal osmóticamente activo de acuerdo con la reivindicación 1, caracterizado porque al menos parte del sistema de administración está cubierto por una membrana compuesta por una composición polimérica que es permeable al paso de agua o fluido acuoso externo presente en la cavidad vaginal, pero es impermeable a las composiciones dentro del sistema. Reivindicación 9: Un sistema de administración vaginal osmóticamente activo de acuerdo con la reivindicación 8, caracterizado porque dicha membrana impermeable o capa de barrera está compuesta por un material que constituye una barrera par la difusión para sustancias farmacéuticamente activas y se selecciona, preferentemente, entre el grupo integrado por Teflón, polímeros de siloxano, copolímeros de Teflón y polímeros de siloxano, poliacrilonitrilo u olefinas. Reivindicación 12: Un sistema de administración vaginal osmóticamente activo de acuerdo con cualquiera de las reivindicaciones anteriores, caracterizado porque el material del cuerpo constituye una barrera para la difusión para sustancias farmacéuticamente activas y se selecciona, preferentemente, entre el grupo de polímeros de siloxano, poliuretano, elastómeros de poliuretano, poliacrilonitrilo, copolímero de etileno-acetato de vinilo (EVA), poliolefinas tales como poliisobutileno, copolímeros de bloque de estireno-butadieno-estireno (SBS, SIS) y copolímeros de estireno-isopreno-butadieno-estireno (SIBS), plásticos termoestables, tales como poliéster o policarbonato, acetatos de celulosa, etilcelulosa y similares.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI20116073 | 2011-11-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR088578A1 true AR088578A1 (es) | 2014-06-18 |
Family
ID=47222137
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP120104055A AR088578A1 (es) | 2011-11-01 | 2012-10-30 | Sistema de administracion vaginal osmoticamente activo |
Country Status (16)
Country | Link |
---|---|
US (1) | US20140309598A1 (es) |
EP (1) | EP2773414A1 (es) |
JP (1) | JP6297495B2 (es) |
KR (1) | KR20140089393A (es) |
CN (1) | CN103974742B (es) |
AR (1) | AR088578A1 (es) |
AU (1) | AU2012330960B2 (es) |
BR (1) | BR112014010509A2 (es) |
CA (1) | CA2853713A1 (es) |
EA (1) | EA026830B9 (es) |
HK (1) | HK1200383A1 (es) |
IL (1) | IL232231A0 (es) |
MX (1) | MX2014005270A (es) |
TW (1) | TWI615155B (es) |
UY (1) | UY34421A (es) |
WO (1) | WO2013064745A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102488491B1 (ko) * | 2013-08-19 | 2023-01-12 | 타리스 바이오메디컬 엘엘씨 | 다중 유닛 약물 전달 장치 및 방법 |
RU2016120199A (ru) * | 2013-11-05 | 2017-12-11 | ТАРИС Биомедикал ЛЛК | Осмотические устройства, комплекты и способы для доставки лекарственных средств |
US20190083428A1 (en) * | 2014-12-19 | 2019-03-21 | Good Clean Love, Inc. | Salt balanced vaginal product and method |
CA2995297C (en) * | 2015-08-11 | 2024-01-02 | Ptt Holding Aps | A delivery device |
MX2018007674A (es) * | 2015-12-21 | 2018-09-12 | Bayer Oy | Un metodo para la fabricacion de un anillo vaginal. |
KR102159904B1 (ko) * | 2020-04-24 | 2020-09-24 | 강경원 | 약물 방출 고리를 구비한 월경컵 |
WO2023200974A1 (en) * | 2022-04-14 | 2023-10-19 | Yale University | Nanoparticles and nanoparticle-releasing vaginal rings |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3453006A (en) * | 1966-03-28 | 1969-07-01 | C & L Ind Inc | Conduit coupling |
IL38539A (en) * | 1971-01-13 | 1974-05-16 | Alza Corp | Osmotic dispenser |
US3760805A (en) * | 1971-01-13 | 1973-09-25 | Alza Corp | Osmotic dispenser with collapsible supply container |
US3760806A (en) * | 1971-01-13 | 1973-09-25 | Alza Corp | Helical osmotic dispenser with non-planar membrane |
SE376851B (es) * | 1971-01-13 | 1975-06-16 | Alza Corp | |
US3845770A (en) * | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US4286587A (en) * | 1978-10-11 | 1981-09-01 | Alza Corporation | Vaginal drug delivery system made from polymer |
US4210139A (en) * | 1979-01-17 | 1980-07-01 | Alza Corporation | Osmotic device with compartment for governing concentration of agent dispensed from device |
US4629449A (en) * | 1982-07-29 | 1986-12-16 | Alza Corporation | Vaginal dispenser for dispensing beneficial hormone |
US4765989A (en) | 1983-05-11 | 1988-08-23 | Alza Corporation | Osmotic device for administering certain drugs |
US4781714A (en) * | 1983-11-02 | 1988-11-01 | Alza Corporation | Dispenser for delivering thermo-responsive composition |
EP0180264A1 (en) * | 1984-10-12 | 1986-05-07 | Akzo N.V. | Release system for two or more active substances |
NL8500470A (nl) * | 1985-02-19 | 1986-09-16 | Achel Homesteel Pvba | Intravaginaal orgaan. |
US5169390A (en) * | 1990-05-21 | 1992-12-08 | Athayde Amulya L | Osmotic infusion device |
EP0768867B1 (en) * | 1994-06-13 | 2002-10-09 | Alza Corporation | Dosage form for administering drug in liquid formulation |
ATE260640T1 (de) * | 1997-12-29 | 2004-03-15 | Alza Corp | Osmotisches verabreichungssystem mit stöpselrückhaltemechanismus |
AU765909C (en) * | 1998-12-17 | 2004-09-23 | Alza Corporation | Conversion of liquid filled gelatin capsules into controlled release systems by multiple coatings |
US6491683B1 (en) * | 1999-09-07 | 2002-12-10 | Alza Corporation | Osmotic dosage form composed of an extruded polymer tube form |
US6632217B2 (en) * | 2001-04-19 | 2003-10-14 | Microsolutions, Inc. | Implantable osmotic pump |
CA2698143C (en) | 2007-06-26 | 2016-01-19 | Warner Chilcott Company, Llc | Intravaginal drug delivery devices for the delivery of macromolecules and water-soluble drugs |
TW200927141A (en) * | 2007-11-22 | 2009-07-01 | Bayer Schering Pharma Oy | Vaginal delivery system |
CN103025320A (zh) * | 2010-03-28 | 2013-04-03 | 伊万斯彻有限公司 | ***内药物递送装置 |
-
2012
- 2012-10-19 TW TW101138598A patent/TWI615155B/zh not_active IP Right Cessation
- 2012-10-30 AR ARP120104055A patent/AR088578A1/es unknown
- 2012-10-30 UY UY0001034421A patent/UY34421A/es not_active Application Discontinuation
- 2012-11-01 EA EA201490862A patent/EA026830B9/ru not_active IP Right Cessation
- 2012-11-01 CN CN201280059918.2A patent/CN103974742B/zh not_active Expired - Fee Related
- 2012-11-01 EP EP12790930.7A patent/EP2773414A1/en not_active Withdrawn
- 2012-11-01 CA CA2853713A patent/CA2853713A1/en not_active Abandoned
- 2012-11-01 BR BR112014010509A patent/BR112014010509A2/pt not_active Application Discontinuation
- 2012-11-01 WO PCT/FI2012/051064 patent/WO2013064745A1/en active Application Filing
- 2012-11-01 KR KR1020147014367A patent/KR20140089393A/ko not_active Application Discontinuation
- 2012-11-01 JP JP2014539372A patent/JP6297495B2/ja not_active Expired - Fee Related
- 2012-11-01 MX MX2014005270A patent/MX2014005270A/es unknown
- 2012-11-01 AU AU2012330960A patent/AU2012330960B2/en not_active Ceased
- 2012-11-01 US US14/356,159 patent/US20140309598A1/en not_active Abandoned
-
2014
- 2014-04-24 IL IL232231A patent/IL232231A0/en not_active IP Right Cessation
-
2015
- 2015-01-26 HK HK15100856.6A patent/HK1200383A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2853713A1 (en) | 2013-05-10 |
BR112014010509A2 (pt) | 2017-04-25 |
TWI615155B (zh) | 2018-02-21 |
EA026830B1 (ru) | 2017-05-31 |
CN103974742A (zh) | 2014-08-06 |
KR20140089393A (ko) | 2014-07-14 |
EA201490862A1 (ru) | 2014-10-30 |
HK1200383A1 (en) | 2015-08-07 |
EP2773414A1 (en) | 2014-09-10 |
IL232231A0 (en) | 2014-06-30 |
TW201328720A (zh) | 2013-07-16 |
AU2012330960B2 (en) | 2017-06-29 |
EA026830B9 (ru) | 2017-11-30 |
JP2015501191A (ja) | 2015-01-15 |
CN103974742B (zh) | 2017-03-08 |
US20140309598A1 (en) | 2014-10-16 |
JP6297495B2 (ja) | 2018-03-20 |
MX2014005270A (es) | 2014-08-22 |
WO2013064745A1 (en) | 2013-05-10 |
AU2012330960A1 (en) | 2014-05-15 |
UY34421A (es) | 2013-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |