AR082876A1 - Sales de bromhidrato de una pirazolilaminoquinazolina - Google Patents

Sales de bromhidrato de una pirazolilaminoquinazolina

Info

Publication number
AR082876A1
AR082876A1 ARP110103207A ARP110103207A AR082876A1 AR 082876 A1 AR082876 A1 AR 082876A1 AR P110103207 A ARP110103207 A AR P110103207A AR P110103207 A ARP110103207 A AR P110103207A AR 082876 A1 AR082876 A1 AR 082876A1
Authority
AR
Argentina
Prior art keywords
salts
pirazolilaminoquinazolina
bromhydrate
salt
pyrozolylaminoquinazaline
Prior art date
Application number
ARP110103207A
Other languages
English (en)
Original Assignee
Ambit Biosciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ambit Biosciences Corp filed Critical Ambit Biosciences Corp
Publication of AR082876A1 publication Critical patent/AR082876A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/99—Enzyme inactivation by chemical treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Sales de bromhidrato de una pirozolilaminoquinazalina y composiciones farmacéuticas de esta. También métodos de uso para tratar, prevenir o mejorar una enfermedad proliferativa.Reivindicación 1: Una sal caracterizada porque es una sal de bromhidrato de (4-fluorofenil)(4-(5-metil-1H-pirazol-3-ilamino)quinazolin-2-il)metanol, o un hidrato o solvato de este aceptable desde el punto de vista farmacéutico.
ARP110103207A 2010-09-01 2011-09-01 Sales de bromhidrato de una pirazolilaminoquinazolina AR082876A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37929110P 2010-09-01 2010-09-01

Publications (1)

Publication Number Publication Date
AR082876A1 true AR082876A1 (es) 2013-01-16

Family

ID=44645807

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP110103207A AR082876A1 (es) 2010-09-01 2011-09-01 Sales de bromhidrato de una pirazolilaminoquinazolina

Country Status (12)

Country Link
US (1) US8633209B2 (es)
EP (1) EP2611792B1 (es)
JP (1) JP5872558B2 (es)
KR (1) KR20130141469A (es)
CN (1) CN103270030B (es)
AR (1) AR082876A1 (es)
AU (1) AU2011296046B2 (es)
CA (1) CA2809983A1 (es)
ES (1) ES2619850T3 (es)
MX (1) MX2013002383A (es)
TW (1) TW201215597A (es)
WO (1) WO2012030885A1 (es)

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Also Published As

Publication number Publication date
CN103270030B (zh) 2016-01-20
US20120053195A1 (en) 2012-03-01
EP2611792B1 (en) 2017-02-01
EP2611792A1 (en) 2013-07-10
MX2013002383A (es) 2013-07-05
JP2013536850A (ja) 2013-09-26
AU2011296046A1 (en) 2013-03-28
WO2012030885A1 (en) 2012-03-08
AU2011296046B2 (en) 2015-05-14
JP5872558B2 (ja) 2016-03-01
TW201215597A (en) 2012-04-16
CN103270030A (zh) 2013-08-28
US8633209B2 (en) 2014-01-21
CA2809983A1 (en) 2012-03-08
KR20130141469A (ko) 2013-12-26
ES2619850T3 (es) 2017-06-27

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