AR052959A1 - Anticuerpos anti- ccr5 y usos de los mismos - Google Patents

Anticuerpos anti- ccr5 y usos de los mismos

Info

Publication number
AR052959A1
AR052959A1 ARP060101255A ARP060101255A AR052959A1 AR 052959 A1 AR052959 A1 AR 052959A1 AR P060101255 A ARP060101255 A AR P060101255A AR P060101255 A ARP060101255 A AR P060101255A AR 052959 A1 AR052959 A1 AR 052959A1
Authority
AR
Argentina
Prior art keywords
num
group
same
cdr1
cdr2
Prior art date
Application number
ARP060101255A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of AR052959A1 publication Critical patent/AR052959A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Un anticuerpo que se une al CCR5 humano formado por una cadena pesada variable y una cadena ligera variable, que se caracteriza en que la cadena pesada variable consta de las secuencias CDR, CDR1, CDR2 y CDR3 y siendo la CDR1 seleccionada de un grupo formado por los ID. DE SEC. NUM: 9, 10, 11, 12; siendo la CDR2 seleccionada del grupo formado por los ID. DE SEC. NUM: 13, 14, 15; y siendo la CDR3 seleccionada de un grupo formado por los ID DE SEC NUM: 16, 17, donde dichas CDR se seleccionan independientemente de cada una o es variante humanizada, quimérica o un fragmento de dicho anticuerpo y tiene unas propiedades ventajosas para el tratamiento de las enfermedades inmunosupresoras.
ARP060101255A 2005-04-01 2006-03-30 Anticuerpos anti- ccr5 y usos de los mismos AR052959A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05007138 2005-04-01

Publications (1)

Publication Number Publication Date
AR052959A1 true AR052959A1 (es) 2007-04-11

Family

ID=34934663

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060101255A AR052959A1 (es) 2005-04-01 2006-03-30 Anticuerpos anti- ccr5 y usos de los mismos

Country Status (19)

Country Link
US (1) US7615216B2 (es)
EP (2) EP1869087A2 (es)
JP (2) JP4733736B2 (es)
KR (1) KR20070116136A (es)
CN (1) CN101175771A (es)
AR (1) AR052959A1 (es)
AU (1) AU2006228663A1 (es)
BR (1) BRPI0609792A2 (es)
CA (1) CA2603692A1 (es)
CR (1) CR9393A (es)
IL (1) IL186071A0 (es)
MA (1) MA29374B1 (es)
MX (1) MX2007011842A (es)
NO (1) NO20074867L (es)
RU (1) RU2007139953A (es)
SG (1) SG151284A1 (es)
TW (1) TW200720289A (es)
WO (1) WO2006103100A2 (es)
ZA (1) ZA200708332B (es)

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TW200817438A (en) 2006-08-17 2008-04-16 Hoffmann La Roche A conjugate of an antibody against CCR5 and an antifusogenic peptide
MX2009002694A (es) 2006-09-29 2009-03-24 Hoffmann La Roche Anticuerpos dirigidos contra ccr5 y usos de los mismos.
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CN104945509A (zh) 2009-09-16 2015-09-30 弗·哈夫曼-拉罗切有限公司 包含卷曲螺旋和/或系链的蛋白质复合体及其用途
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MX341958B (es) * 2011-02-23 2016-09-08 Hoffmann La Roche Anticuerpos contra el il33r humano y usos de los mismos.
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Also Published As

Publication number Publication date
AU2006228663A1 (en) 2006-10-05
ZA200708332B (en) 2009-04-29
US20070036796A1 (en) 2007-02-15
RU2007139953A (ru) 2009-05-10
US7615216B2 (en) 2009-11-10
JP2011079836A (ja) 2011-04-21
CR9393A (es) 2008-02-20
EP2336183A2 (en) 2011-06-22
TW200720289A (en) 2007-06-01
EP1869087A2 (en) 2007-12-26
MX2007011842A (es) 2007-10-11
WO2006103100A2 (en) 2006-10-05
CN101175771A (zh) 2008-05-07
CA2603692A1 (en) 2006-10-05
JP2008533998A (ja) 2008-08-28
WO2006103100A3 (en) 2006-12-28
MA29374B1 (fr) 2008-04-01
BRPI0609792A2 (pt) 2010-04-27
KR20070116136A (ko) 2007-12-06
NO20074867L (no) 2007-12-07
EP2336183A3 (en) 2011-10-12
JP4733736B2 (ja) 2011-07-27
IL186071A0 (en) 2008-01-20
SG151284A1 (en) 2009-04-30

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