AR033758A1 - Compuestos 4-(fenil-(piperidinil-4-il)amino)benzamida - Google Patents
Compuestos 4-(fenil-(piperidinil-4-il)amino)benzamidaInfo
- Publication number
- AR033758A1 AR033758A1 ARP020101814A ARP020101814A AR033758A1 AR 033758 A1 AR033758 A1 AR 033758A1 AR P020101814 A ARP020101814 A AR P020101814A AR P020101814 A ARP020101814 A AR P020101814A AR 033758 A1 AR033758 A1 AR 033758A1
- Authority
- AR
- Argentina
- Prior art keywords
- phenyl
- compounds
- ring
- piperidinil
- benzamida
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Se revelan y reivindican compuestos de la Fórmula General 1: en la cual R1 es seleccionado entre cualquiera de los siguientes: fenilo, piridinilo; tienilo; furanilo; imidazolilo; pirrolilo, triazolilo, tiazolilo; y N-óxido de piridilo en los cuales cada uno de los anillos fenilo R1 y heteroaromático R1 puede opcionalmente e independientemente de los demás estar adicionalmente sustituido por 1, 2, o 3 sustituyentes seleccionados de entre el grupo consistente en alquilo de C1-6 lineal o ramificado, NO2, CF3, alcoxi de C1-6, cloro, flúor, bromo e iodo Las sustituciones en el anillo fenilo y en el anillo heteroaromático pueden tener lugar en cualquier posición en dichos sistemas -anillo; como también sus sales y las composiciones farmacéuticas que comprenden los novedosos compuestos y su utilización en la terapia, en particular en el tratamiento del dolor, ansiedad y trastornos funcionales gastrointestinales.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0101769A SE0101769D0 (sv) | 2001-05-18 | 2001-05-18 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
AR033758A1 true AR033758A1 (es) | 2004-01-07 |
Family
ID=20284172
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP020101814A AR033758A1 (es) | 2001-05-18 | 2002-05-16 | Compuestos 4-(fenil-(piperidinil-4-il)amino)benzamida |
Country Status (26)
Country | Link |
---|---|
US (1) | US7226933B2 (es) |
EP (1) | EP1395555B1 (es) |
JP (1) | JP2005508289A (es) |
KR (1) | KR20030094425A (es) |
CN (1) | CN1639123A (es) |
AR (1) | AR033758A1 (es) |
AT (1) | ATE313528T1 (es) |
BG (1) | BG108330A (es) |
BR (1) | BR0209670A (es) |
CA (1) | CA2446311A1 (es) |
CO (1) | CO5540317A2 (es) |
CZ (1) | CZ20033089A3 (es) |
DE (1) | DE60208192T2 (es) |
EE (1) | EE200300554A (es) |
HU (1) | HUP0401328A2 (es) |
IL (1) | IL158628A0 (es) |
IS (1) | IS7028A (es) |
MX (1) | MXPA03010440A (es) |
NO (1) | NO20035113D0 (es) |
NZ (1) | NZ529398A (es) |
PL (1) | PL366387A1 (es) |
RU (1) | RU2003131966A (es) |
SE (1) | SE0101769D0 (es) |
SK (1) | SK13912003A3 (es) |
WO (1) | WO2002094782A1 (es) |
ZA (1) | ZA200308631B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
OA12790A (en) * | 2002-03-13 | 2006-07-10 | Janssen Pharmaceutica Nv | New inhibitors of histone deacetylase. |
SE0300987D0 (sv) * | 2003-04-03 | 2003-04-03 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
AU2004278414B2 (en) | 2003-10-01 | 2012-05-24 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
US7598261B2 (en) | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
US7576207B2 (en) | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
EP2063886A2 (en) * | 2006-09-12 | 2009-06-03 | Adolor Corporation | Use of n-containing spirocompounds for the enhancement of cognitive function |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4091096A (en) | 1976-03-19 | 1978-05-23 | Eli Lilly And Company | Dinitroanilines for the control of phytopathogens |
EG12406A (en) | 1976-08-12 | 1979-03-31 | Janssen Pharmaceutica Nv | Process for preparing of novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides |
US4252812A (en) | 1977-05-23 | 1981-02-24 | Pfizer Inc. | 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles |
SE441448B (sv) | 1977-05-23 | 1985-10-07 | Pfizer | Sett att framstella hexahydro-gamma-karbolinforeningar |
DE3200304A1 (de) | 1981-01-16 | 1982-08-26 | Sandoz-Patent-GmbH, 7850 Lörrach | 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel |
DE3563964D1 (en) | 1984-10-16 | 1988-09-01 | Synthelabo | Piperidine derivatives, their preparation and their therapeutical application |
KR940003491B1 (ko) | 1989-08-10 | 1994-04-23 | 리히터 게데온 베기에스제티 기아르 알.티 | 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물 |
YU150489A (sh) | 1989-08-10 | 1992-12-21 | W.L. Gore & Co. Gmbh. | Uređaj za ispitivanje odevnih predmeta na nepromočivost |
US5854245A (en) | 1996-06-28 | 1998-12-29 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
SE9604786D0 (sv) * | 1996-12-20 | 1996-12-20 | Astra Pharma Inc | New compounds |
TW548271B (en) * | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
JP4754068B2 (ja) | 1997-12-24 | 2011-08-24 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | δ−オピオイドレセプターに結合する4−[アリール(ピペリジン−4−イル)]アミノベンズアミド類 |
WO1999045925A1 (en) | 1998-03-10 | 1999-09-16 | Research Triangle Institute | Novel opiate compounds, methods of making and methods of use |
SE9904675D0 (sv) * | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
JP2003525938A (ja) * | 2000-03-03 | 2003-09-02 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | 3−(ジアリールメチレン)−8−アザビシクロ[3.2.1]オクタン誘導体 |
SE0001207D0 (sv) * | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
WO2009028275A1 (ja) * | 2007-08-28 | 2009-03-05 | Konica Minolta Medical & Graphic, Inc. | シンチレータパネル |
-
2001
- 2001-05-18 SE SE0101769A patent/SE0101769D0/xx unknown
-
2002
- 2002-05-16 BR BR0209670-6A patent/BR0209670A/pt not_active IP Right Cessation
- 2002-05-16 US US10/477,852 patent/US7226933B2/en not_active Expired - Fee Related
- 2002-05-16 JP JP2002591455A patent/JP2005508289A/ja active Pending
- 2002-05-16 MX MXPA03010440A patent/MXPA03010440A/es unknown
- 2002-05-16 EE EEP200300554A patent/EE200300554A/xx unknown
- 2002-05-16 RU RU2003131966/04A patent/RU2003131966A/ru not_active Application Discontinuation
- 2002-05-16 CA CA002446311A patent/CA2446311A1/en not_active Abandoned
- 2002-05-16 IL IL15862802A patent/IL158628A0/xx unknown
- 2002-05-16 DE DE60208192T patent/DE60208192T2/de not_active Expired - Fee Related
- 2002-05-16 NZ NZ529398A patent/NZ529398A/en unknown
- 2002-05-16 HU HU0401328A patent/HUP0401328A2/hu unknown
- 2002-05-16 AT AT02733702T patent/ATE313528T1/de not_active IP Right Cessation
- 2002-05-16 KR KR10-2003-7014946A patent/KR20030094425A/ko not_active Application Discontinuation
- 2002-05-16 EP EP02733702A patent/EP1395555B1/en not_active Expired - Lifetime
- 2002-05-16 CN CNA028141601A patent/CN1639123A/zh active Pending
- 2002-05-16 CZ CZ20033089A patent/CZ20033089A3/cs unknown
- 2002-05-16 AR ARP020101814A patent/AR033758A1/es unknown
- 2002-05-16 SK SK1391-2003A patent/SK13912003A3/sk unknown
- 2002-05-16 WO PCT/SE2002/000944 patent/WO2002094782A1/en active IP Right Grant
- 2002-05-16 PL PL02366387A patent/PL366387A1/xx not_active Application Discontinuation
-
2003
- 2003-11-05 ZA ZA200308631A patent/ZA200308631B/xx unknown
- 2003-11-07 BG BG108330A patent/BG108330A/bg unknown
- 2003-11-12 IS IS7028A patent/IS7028A/is unknown
- 2003-11-12 CO CO03100165A patent/CO5540317A2/es not_active Application Discontinuation
- 2003-11-17 NO NO20035113A patent/NO20035113D0/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NZ529398A (en) | 2005-08-26 |
NO20035113D0 (no) | 2003-11-17 |
ATE313528T1 (de) | 2006-01-15 |
RU2003131966A (ru) | 2005-05-10 |
DE60208192D1 (de) | 2006-01-26 |
JP2005508289A (ja) | 2005-03-31 |
DE60208192T2 (de) | 2006-07-13 |
BR0209670A (pt) | 2004-04-20 |
SE0101769D0 (sv) | 2001-05-18 |
IL158628A0 (en) | 2004-05-12 |
PL366387A1 (en) | 2005-01-24 |
CZ20033089A3 (en) | 2004-06-16 |
ZA200308631B (en) | 2005-02-07 |
WO2002094782A1 (en) | 2002-11-28 |
SK13912003A3 (sk) | 2004-04-06 |
US20040235897A1 (en) | 2004-11-25 |
CO5540317A2 (es) | 2005-07-29 |
US7226933B2 (en) | 2007-06-05 |
HUP0401328A2 (hu) | 2004-12-28 |
IS7028A (is) | 2003-11-12 |
BG108330A (bg) | 2004-12-30 |
CN1639123A (zh) | 2005-07-13 |
EP1395555A1 (en) | 2004-03-10 |
EE200300554A (et) | 2004-02-16 |
KR20030094425A (ko) | 2003-12-11 |
EP1395555B1 (en) | 2005-12-21 |
CA2446311A1 (en) | 2002-11-28 |
MXPA03010440A (es) | 2004-03-09 |
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Legal Events
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FB | Suspension of granting procedure |