AR025146A1 - UNA MOLÉCULA AISLADA DE POLINUCLEoTIDO QUE COMPRENDE UNA SECUENCIA DE ADN QUE CODIFICA UN VIRUS PRRS NORTEAMERICANO, CÉLULA HUESPED, PLÁSMIDO, MÉTODO PARA GENERAR UN VIRUS PRRS NORTEAMERICANO Y VACUNA. - Google Patents
UNA MOLÉCULA AISLADA DE POLINUCLEoTIDO QUE COMPRENDE UNA SECUENCIA DE ADN QUE CODIFICA UN VIRUS PRRS NORTEAMERICANO, CÉLULA HUESPED, PLÁSMIDO, MÉTODO PARA GENERAR UN VIRUS PRRS NORTEAMERICANO Y VACUNA.Info
- Publication number
- AR025146A1 AR025146A1 ARP990106325A AR025146A1 AR 025146 A1 AR025146 A1 AR 025146A1 AR P990106325 A ARP990106325 A AR P990106325A AR 025146 A1 AR025146 A1 AR 025146A1
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- north american
- american prrs
- isolated
- prrs virus
- viral vectors
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Abstract
Se describe una molécula aislada de polinucleotidos inclusive plásmidos; vectores víricos; y células hospedantes transfectadas que comprenden una secuenciade ADN que codifica una secuencia infecciosa de ARN que a su vez codifica un virus de PRRSnort eamericano; y también los virus del PRRS norteamericano,codificados de este modo. Además se proporcionan moléculas infecciosas aisladas de ARN que codifica un virus del PRRS norteamericano. Se describen tambiénmoléculas aisladas depolinucleotidos, m oléculas infecciosas de ARN, vectores víricos, y células hospedantes transfectadas que codifican los virus del PRRSnorteamericano, modificados genéticamente ; y los virus del PRRS norteamericano, modificados genéticamente,codificados de este modo. S e describen tambiénvacunas que comprenden dichos plásmidos, dichas moléculas de ARN, dichos vectores víricos y dichos virus del PRRS norteamericano, y métodos de usar estasvacunas en cerdos y en otros animales. También seproporcionan moléculas aisla das de polinucleotidos, vectores víricos, y células hospedantes transfectadas quecomprenden una secuencia de nucleotidos, que codifica un péptido de un virus del PRRS norteamericano. Estos vectores víricos y estas líneasde célulashospedantes transfe ctadas son utiles para proporcionar péptidos con el fin de compensar secuencias de codificacion de péptidos mutados de secuencias de ADN quecodifican virus del PRRS norteamericano modificados genéticamente de manera talque se pueden generar viriones funcionales.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11334598P | 1998-12-22 | 1998-12-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR025146A1 true AR025146A1 (es) | 2002-11-13 |
Family
ID=22348908
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP990106325 AR025146A1 (es) | 1998-12-22 | 1999-12-13 | UNA MOLÉCULA AISLADA DE POLINUCLEoTIDO QUE COMPRENDE UNA SECUENCIA DE ADN QUE CODIFICA UN VIRUS PRRS NORTEAMERICANO, CÉLULA HUESPED, PLÁSMIDO, MÉTODO PARA GENERAR UN VIRUS PRRS NORTEAMERICANO Y VACUNA. |
ARP070101362 AR058249A2 (es) | 1998-12-22 | 2007-03-30 | Una molecula aislada de polinucleotido que comprende una secuencia de adn que codifica una molecula infecciosa de arn que codifica un virus prrs norteamericano, celula transfectada y vacuna |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP070101362 AR058249A2 (es) | 1998-12-22 | 2007-03-30 | Una molecula aislada de polinucleotido que comprende una secuencia de adn que codifica una molecula infecciosa de arn que codifica un virus prrs norteamericano, celula transfectada y vacuna |
Country Status (18)
Country | Link |
---|---|
US (2) | US6500662B1 (es) |
EP (2) | EP1627919B1 (es) |
JP (7) | JP4113642B2 (es) |
CN (1) | CN1171996C (es) |
AR (2) | AR025146A1 (es) |
AT (1) | ATE309364T1 (es) |
AU (1) | AU769841B2 (es) |
BR (1) | BRPI9905902B8 (es) |
CA (2) | CA2440933A1 (es) |
CY (2) | CY1105680T1 (es) |
DE (1) | DE69928209T9 (es) |
DK (2) | DK1627919T3 (es) |
ES (2) | ES2251162T3 (es) |
HK (1) | HK1029140A1 (es) |
MX (1) | MXPA03009354A (es) |
NZ (2) | NZ501264A (es) |
PT (1) | PT1627919E (es) |
ZA (1) | ZA997289B (es) |
Families Citing this family (46)
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US7691389B2 (en) * | 1998-12-22 | 2010-04-06 | Pfizer Inc | Infectious cDNA clone of north american porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
US7618797B2 (en) | 1998-12-22 | 2009-11-17 | Pfizer Inc | Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
CA2366072C (en) * | 1999-03-08 | 2007-07-10 | Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. | Prrsv vaccines |
PT2251419E (pt) | 1999-04-22 | 2012-09-03 | Us Agriculture | Vacina contra a síndrome reprodutiva e respiratória porcina com base no isolado ja-142 |
WO2002038753A1 (fr) * | 2000-11-09 | 2002-05-16 | Junichi Watanabe | Procede de criblage d'un gene agissant sur les conditions pathologiques ou la survie d'un animal infecte par un pathogene |
US6841364B2 (en) | 2002-01-22 | 2005-01-11 | Protatek International, Inc. | Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof |
US7906311B2 (en) * | 2002-03-20 | 2011-03-15 | Merial Limited | Cotton rat lung cells for virus culture |
WO2005009462A2 (en) * | 2003-07-24 | 2005-02-03 | Merial Limited | Vaccine formulations comprising an oil-in-water emulsion |
CA2571452A1 (en) | 2004-06-18 | 2006-01-26 | Regents Of The University Of Minnesota | Identifying virally infected and vaccinated organisms |
KR100872840B1 (ko) | 2004-07-09 | 2008-12-22 | (주)씨아이디 | 돼지생식기호흡기증후군 바이러스에 대한 전체-길이의감염성이 있는 cDNA 클론 및 이의 용도 |
US7632636B2 (en) * | 2004-09-21 | 2009-12-15 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome isolates and methods of use |
MX2007005708A (es) * | 2004-11-11 | 2007-07-09 | Pfizer Prod Inc | Virus del sindrome reproductor y respiratorio porcino mutante. |
AU2006205852A1 (en) | 2005-01-13 | 2006-07-20 | Boehringer Ingelheim Vetmedica Gmbh | Improved PRRS vaccines |
EP1856141A1 (en) * | 2005-02-25 | 2007-11-21 | Pfizer Products Inc. | N protein mutants of porcine reproductive and respiratory syndrome virus |
US8110390B2 (en) * | 2005-06-24 | 2012-02-07 | Regents Of The University Of Minnesota | PRRS viruses, infectious clones, mutants thereof, and methods of use |
US7608272B2 (en) * | 2005-08-30 | 2009-10-27 | Board Of Regents Of The University Of Nebraska | Methods and compositions for vaccination of animals with PRRSV antigens with improved immunogenicity |
PL2106440T3 (pl) | 2007-01-12 | 2016-02-29 | Univ Illinois | Komórki niepochodzące od małp do hodowli wirusa zespołu rozrodczo-oddechowego świń (PRRS) |
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EP2181189B1 (en) * | 2007-06-25 | 2012-06-20 | South Dakota State University | Recombinant north american type 1 porcine reproductive and respiratory syndrome virus and methods of use |
EP2328612A4 (en) * | 2008-08-25 | 2012-11-14 | Boehringer Ingelheim Vetmed | VACCINE AGAINST HIGH PATHOGENIC DISEASED LATE LIVESTOCK (PRRS) |
US8012735B2 (en) * | 2009-03-02 | 2011-09-06 | University Of Kentucky Research Foundation | Infectious cDNA clone of the modified live virus vaccine strain of Equine arteritis virus |
AR078253A1 (es) | 2009-09-02 | 2011-10-26 | Boehringer Ingelheim Vetmed | Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad |
DK2475384T3 (en) * | 2009-09-10 | 2016-10-24 | Merial Inc | NEW VACCINE FORMULATIONS COMPREHENSIVE saponin-CONTAINING ADJUVANTS |
UA108902C2 (uk) | 2010-11-10 | 2015-06-25 | Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування | |
EP2675476B1 (en) | 2011-02-17 | 2015-09-16 | Boehringer Ingelheim Vetmedica GmbH | Commercial scale process for production of prrsv |
EA038012B1 (ru) | 2011-02-17 | 2021-06-23 | Бёрингер Ингельхайм Ветмедика Гмбх | Композиция на основе нового штамма prrsv или его белков, продукт, их применение, вирус prrsv, выделенная нк и рекомбинантный вектор экспрессии для получения этого вируса |
US9187731B2 (en) | 2011-07-29 | 2015-11-17 | Boehringer Ingelheim Vetmedica Gmbh | PRRS virus inducing type I interferon in susceptible cells |
EP2737058A1 (en) | 2011-07-29 | 2014-06-04 | Boehringer Ingelheim Vetmedica GmbH | INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF |
UA114504C2 (uk) | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs |
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CN105073130A (zh) | 2013-03-15 | 2015-11-18 | 勃林格殷格翰动物保健公司 | 猪生殖与呼吸综合征病毒、组合物、疫苗及使用方法 |
EP4091629A1 (en) | 2013-09-25 | 2022-11-23 | Zoetis Services LLC | Pcv2b divergent vaccine composition and methods of use |
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TWI554609B (zh) | 2014-11-19 | 2016-10-21 | 國立屏東科技大學 | 抗豬生殖與呼吸綜合症病毒感染之重組融合抗原基因、重組融合抗原蛋白及含彼之次單位疫苗組成物 |
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