ZA992094B - Bicyclo [2.2.1] heptanes and related compounds. - Google Patents

Bicyclo [2.2.1] heptanes and related compounds.

Info

Publication number: ZA992094B
Authority: ZA; South Africa
Prior art keywords: heptanes; bicyclo; related compounds; compounds
Prior art date: 1998-03-17

Application number

ZA9902094A

Other languages

English (en)

Inventor

Bertrand Leo Chenard

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-17

Filing date

1999-03-16

Publication date

2000-11-28

1999-03-16 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2000-11-28 Publication of ZA992094B publication Critical patent/ZA992094B/xx

Links

150000001875 compounds Chemical class 0.000 title 1
UMRZSTCPUPJPOJ-UHFFFAOYSA-N norbornane Chemical class C1CC2CCC1C2 UMRZSTCPUPJPOJ-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C229/50—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms being part of the same condensed ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
- C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms

ZA9902094A 1998-03-17 1999-03-16 Bicyclo [2.2.1] heptanes and related compounds. ZA992094B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US7834698P	1998-03-17	1998-03-17

Publications (1)

Publication Number	Publication Date
ZA992094B true ZA992094B (en)	2000-11-28

Family

ID=22143450

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9902094A ZA992094B (en)	1998-03-17	1999-03-16	Bicyclo [2.2.1] heptanes and related compounds.

Country Status (40)

Country	Link
US (1)	US6136861A (xx)
EP (1)	EP1064256B1 (xx)
JP (1)	JP3665567B2 (xx)
KR (1)	KR100372981B1 (xx)
CN (1)	CN1231461C (xx)
AP (1)	AP1116A (xx)
AR (1)	AR017236A1 (xx)
AT (1)	ATE272608T1 (xx)
AU (1)	AU753422B2 (xx)
BG (1)	BG104837A (xx)
BR (1)	BR9908850A (xx)
CA (1)	CA2321639C (xx)
CO (1)	CO5090835A1 (xx)
CZ (1)	CZ20003355A3 (xx)
DE (1)	DE69919142T2 (xx)
DZ (1)	DZ2745A1 (xx)
EA (1)	EA003946B1 (xx)
ES (1)	ES2224604T3 (xx)
GT (1)	GT199900040A (xx)
HR (1)	HRP20000611A2 (xx)
HU (1)	HUP0101031A3 (xx)
ID (1)	ID25651A (xx)
IL (1)	IL138342A0 (xx)
IS (1)	IS5592A (xx)
MA (1)	MA26614A1 (xx)
MY (1)	MY121047A (xx)
NO (1)	NO20004626L (xx)
NZ (1)	NZ506227A (xx)
OA (1)	OA11488A (xx)
PE (1)	PE20000339A1 (xx)
PL (1)	PL343278A1 (xx)
PT (1)	PT1064256E (xx)
SK (1)	SK13532000A3 (xx)
TN (1)	TNSN99039A1 (xx)
TR (1)	TR200002671T2 (xx)
TW (1)	TW509667B (xx)
UA (1)	UA53781C2 (xx)
WO (1)	WO1999047490A1 (xx)
YU (1)	YU53700A (xx)
ZA (1)	ZA992094B (xx)

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US6750364B2 (en)	2001-06-29	2004-06-15	Wyeth	Bridged tricyclic analogs of 2-(carboxycyclopropyl)glycine as inhibitors of glutamate transport
US6562816B2 (en)	2001-08-24	2003-05-13	Pharmacia & Upjohn Company	Substituted-heteroaryl-7-aza[2.2.1]bicycloheptanes for the treatment of disease
US7232798B2 (en) *	2001-11-13	2007-06-19	Tran Loi H	Neuroprotection and neuroegenisis by administering cyclic prolyl glycine
FR2872045B1 (fr) *	2004-06-28	2006-09-29	Centre Nat Rech Scient Cnrse	Medicaments pour le traitement specifique de symptomes de la maladie de parkinson
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KR20100065191A (ko)	2007-09-14	2010-06-15	오르토-맥닐-얀센 파마슈티칼스 인코포레이티드	１,３-이치환된 ４-(아릴-ｘ-페닐)-１ｈ-피리딘-２-온
TW200927731A (en) *	2007-09-14	2009-07-01	Ortho Mcneil Janssen Pharm	1,3-disubstituted-4-phenyl-1H-pyridin-2-ones
CN101801951B (zh)	2007-09-14	2013-11-13	杨森制药有限公司	1’,3’-二取代的-4-苯基-3,4,5,6-四氢-2h,1’h-[1,4’]二吡啶-2’-酮
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RU2510396C2 (ru)	2008-09-02	2014-03-27	Янссен Фармасьютикалз, Инк.	3-азабицикло[3.1.0]гексильные производные в качестве модуляторов метаботропных глутаматных рецепторов
BRPI0920354A2 (pt)	2008-10-16	2017-06-27	Addex Pharmaceuticals Sa	derivados de indol e benzomorfolina como moduladores de receptores de glutamato metabotrópicos
AU2009319387B2 (en)	2008-11-28	2012-05-10	Addex Pharma S.A.	Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors
JP5707390B2 (ja)	2009-05-12	2015-04-30	ジャンセンファーマシューティカルズ，インコーポレイテッド	１，２，４−トリアゾロ［４，３−ａ］ピリジン誘導体およびｍＧｌｕＲ２受容体の正のアロステリック調節因子としてのその使用
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AR083845A1 (es) *	2010-11-18	2013-03-27	Lilly Co Eli	COMPUESTOS 3-FENILSULFANILMETIL-BICICLO[3.1.0]HEXANO 4-SUSTITUIDOS COMO ANTAGONISTAS DE mGluR2/3
US9447026B2 (en)	2013-03-14	2016-09-20	Kalyra Pharmaceuticals, Inc.	Bicyclic analgesic compounds
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JO3367B1 (ar)	2013-09-06	2019-03-13	Janssen Pharmaceutica Nv	مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
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ES2860298T3 (es)	2014-01-21	2021-10-04	Janssen Pharmaceutica Nv	Combinaciones que comprenden moduladores alostéricos positivos del receptor glutamatérgico metabotrópico de subtipo 2 y su uso
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CN106232567B (zh)	2014-03-07	2021-11-02	里科瑞尔姆Ip控股有限责任公司	螺桨烷衍生物及合成
EP3193855B1 (en)	2014-09-17	2021-05-19	Recurium IP Holdings, LLC	Bicyclic compounds
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KR102157141B1 (ko)	2018-11-27	2020-09-17	주식회사 파미니티	으아리 추출물을 유효 성분으로 포함하는 인지 기능 개선용 조성물
KR102172916B1 (ko)	2018-12-07	2020-11-02	주식회사 파미니티	실크 펩타이드 및 천연 추출물을 포함하는 인지 기능 개선용 조성물
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1999
- 1999-03-04 EP EP99905122A patent/EP1064256B1/en not_active Expired - Lifetime
- 1999-03-04 NZ NZ506227A patent/NZ506227A/xx unknown
- 1999-03-04 CZ CZ20003355A patent/CZ20003355A3/cs unknown
- 1999-03-04 PL PL99343278A patent/PL343278A1/xx unknown
- 1999-03-04 WO PCT/IB1999/000376 patent/WO1999047490A1/en not_active Application Discontinuation
- 1999-03-04 JP JP2000536687A patent/JP3665567B2/ja not_active Expired - Fee Related
- 1999-03-04 AT AT99905122T patent/ATE272608T1/de not_active IP Right Cessation
- 1999-03-04 PT PT99905122T patent/PT1064256E/pt unknown
- 1999-03-04 AU AU25409/99A patent/AU753422B2/en not_active Ceased
- 1999-03-04 BR BR9908850-9A patent/BR9908850A/pt not_active Application Discontinuation
- 1999-03-04 HU HU0101031A patent/HUP0101031A3/hu unknown
- 1999-03-04 DE DE69919142T patent/DE69919142T2/de not_active Expired - Fee Related
- 1999-03-04 ES ES99905122T patent/ES2224604T3/es not_active Expired - Lifetime
- 1999-03-04 CA CA002321639A patent/CA2321639C/en not_active Expired - Fee Related
- 1999-03-04 EA EA200000842A patent/EA003946B1/ru not_active IP Right Cessation
- 1999-03-04 CN CNB998040401A patent/CN1231461C/zh not_active Expired - Fee Related
- 1999-03-04 YU YU53700A patent/YU53700A/sh unknown
- 1999-03-04 US US09/380,727 patent/US6136861A/en not_active Expired - Fee Related
- 1999-03-04 ID IDW20001811A patent/ID25651A/id unknown
- 1999-03-04 KR KR10-2000-7010264A patent/KR100372981B1/ko not_active IP Right Cessation
- 1999-03-04 TR TR2000/02671T patent/TR200002671T2/xx unknown
- 1999-03-04 IL IL13834299A patent/IL138342A0/xx unknown
- 1999-03-04 SK SK1353-2000A patent/SK13532000A3/sk unknown
- 1999-03-10 AP APAP/P/1999/001482A patent/AP1116A/en active
- 1999-03-12 PE PE1999000198A patent/PE20000339A1/es not_active Application Discontinuation
- 1999-03-12 TW TW088103874A patent/TW509667B/zh not_active IP Right Cessation
- 1999-03-15 AR ARP990101118A patent/AR017236A1/es unknown
- 1999-03-15 MY MYPI99000966A patent/MY121047A/en unknown
- 1999-03-16 MA MA25498A patent/MA26614A1/fr unknown
- 1999-03-16 GT GT199900040A patent/GT199900040A/es unknown
- 1999-03-16 DZ DZ990046A patent/DZ2745A1/xx active
- 1999-03-16 TN TNTNSN99039A patent/TNSN99039A1/fr unknown
- 1999-03-16 ZA ZA9902094A patent/ZA992094B/xx unknown
- 1999-03-17 CO CO99016567A patent/CO5090835A1/es unknown
- 1999-04-03 UA UA2000095327A patent/UA53781C2/uk unknown
2000
- 2000-08-18 IS IS5592A patent/IS5592A/is unknown
- 2000-09-15 NO NO20004626A patent/NO20004626L/no not_active Application Discontinuation
- 2000-09-15 HR HR20000611A patent/HRP20000611A2/hr not_active Application Discontinuation
- 2000-09-18 OA OA1200000258A patent/OA11488A/en unknown
- 2000-10-11 BG BG104837A patent/BG104837A/bg unknown

Also Published As

Publication number	Publication date
SK13532000A3 (sk)	2002-07-02
IL138342A0 (en)	2001-10-31
UA53781C2 (uk)	2003-02-17
JP2002506847A (ja)	2002-03-05
PT1064256E (pt)	2004-10-29
TW509667B (en)	2002-11-11
PE20000339A1 (es)	2000-05-13
PL343278A1 (en)	2001-08-13
DE69919142T2 (de)	2005-01-20
JP3665567B2 (ja)	2005-06-29
YU53700A (sh)	2002-11-15
NZ506227A (en)	2003-06-30
HUP0101031A3 (en)	2003-05-28
BG104837A (bg)	2001-07-31
GT199900040A (es)	2000-09-06
ID25651A (id)	2000-10-19
CZ20003355A3 (cs)	2002-05-15
WO1999047490A1 (en)	1999-09-23
CO5090835A1 (es)	2001-10-30
KR20010041951A (ko)	2001-05-25
MA26614A1 (fr)	2004-12-20
AU2540999A (en)	1999-10-11
CA2321639C (en)	2005-08-02
EA003946B1 (ru)	2003-10-30
NO20004626L (no)	2000-11-13
NO20004626D0 (no)	2000-09-15
IS5592A (is)	2000-08-18
KR100372981B1 (ko)	2003-02-25
TNSN99039A1 (fr)	2005-11-10
BR9908850A (pt)	2000-11-21
CN1293655A (zh)	2001-05-02
EA200000842A1 (ru)	2001-04-23
ES2224604T3 (es)	2005-03-01
AR017236A1 (es)	2001-08-22
CA2321639A1 (en)	1999-09-23
AU753422B2 (en)	2002-10-17
HUP0101031A2 (hu)	2001-08-28
AP1116A (en)	2002-10-21
DE69919142D1 (de)	2004-09-09
DZ2745A1 (fr)	2003-09-08
EP1064256A1 (en)	2001-01-03
OA11488A (en)	2004-05-07
MY121047A (en)	2005-12-30
CN1231461C (zh)	2005-12-14
TR200002671T2 (tr)	2000-12-21
HRP20000611A2 (en)	2001-04-30
ATE272608T1 (de)	2004-08-15
AP9901482A0 (en)	1999-03-31
EP1064256B1 (en)	2004-08-04
US6136861A (en)	2000-10-24

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