ZA966163B - Novel galanthamine derivatives, process for the preparation thereof, their application as medical drugs, and pharmaceutical compositions containing said derivatives. - Google Patents

Novel galanthamine derivatives, process for the preparation thereof, their application as medical drugs, and pharmaceutical compositions containing said derivatives.

Info

Publication number
ZA966163B
ZA966163B ZA9606163A ZA966163A ZA966163B ZA 966163 B ZA966163 B ZA 966163B ZA 9606163 A ZA9606163 A ZA 9606163A ZA 966163 A ZA966163 A ZA 966163A ZA 966163 B ZA966163 B ZA 966163B
Authority
ZA
South Africa
Prior art keywords
derivatives
pharmaceutical compositions
compositions containing
preparation
application
Prior art date
Application number
ZA9606163A
Other languages
English (en)
Inventor
Claude Thal
Aude Mary
Pierre Potier
Dolor Renko
Yves Christen
Catherine Guillou
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of ZA966163B publication Critical patent/ZA966163B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA9606163A 1995-07-19 1996-07-19 Novel galanthamine derivatives, process for the preparation thereof, their application as medical drugs, and pharmaceutical compositions containing said derivatives. ZA966163B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9514821.9A GB9514821D0 (en) 1995-07-19 1995-07-19 Galanthamine derivatives

Publications (1)

Publication Number Publication Date
ZA966163B true ZA966163B (en) 1997-02-10

Family

ID=10777948

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9606163A ZA966163B (en) 1995-07-19 1996-07-19 Novel galanthamine derivatives, process for the preparation thereof, their application as medical drugs, and pharmaceutical compositions containing said derivatives.

Country Status (16)

Country Link
US (1) US5958903A (xx)
EP (1) EP0839149B9 (xx)
JP (1) JP4177894B2 (xx)
AT (1) ATE264332T1 (xx)
AU (1) AU6662396A (xx)
CA (1) CA2227235C (xx)
DE (1) DE69632194T2 (xx)
DK (1) DK0839149T3 (xx)
ES (1) ES2218596T3 (xx)
GB (1) GB9514821D0 (xx)
IL (1) IL122739A0 (xx)
MX (1) MX9800407A (xx)
NO (1) NO980215L (xx)
PT (1) PT839149E (xx)
WO (1) WO1997003987A1 (xx)
ZA (1) ZA966163B (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1891954A3 (en) * 1998-09-30 2009-01-14 Takeda Pharmaceutical Company Limited Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder
JP5558648B2 (ja) 1998-11-23 2014-07-23 デイビス、ボニー アセチルコリンエステラーゼ阻害剤のための投与製剤
PT1140105E (pt) 1998-12-24 2004-03-31 Janssen Pharmaceutica Nv Composicao de galantamina de libertacao controlada
US8603546B2 (en) * 1999-01-11 2013-12-10 Herbaceuticals Inc. Herbal supplement for increased muscle strength and endurance for athletes
ATE355066T1 (de) * 1999-01-11 2006-03-15 Atanas Russinov Djananov Nahrungszusatz aus kräutern zur steigerung der muskulären kraft und ausdauer von athleten
WO2000059544A1 (fr) * 1999-03-31 2000-10-12 Eisai Co., Ltd. Compositions stabilisees contenant des medicaments nootropes
EP1181294B1 (de) * 2000-03-31 2004-03-31 Sanochemia Pharmazeutika Aktiengesellschaft Neue derivate und analoga von galanthamin
DE10129265A1 (de) * 2001-06-18 2003-01-02 Hf Arzneimittelforsch Gmbh Wirkstoff-Kombination zur medikamentösen Sucht- oder Rauschmitteltherapie
JP4721386B2 (ja) * 2001-07-10 2011-07-13 第一三共株式会社 新規ガランタミン類縁体
DE10134038A1 (de) * 2001-07-12 2003-02-06 Hf Arzneimittelforsch Gmbh Wirkstoff-Kombination zur medikamentösen Therapie der Nikotinabhängigkeit
EP1681291A1 (de) * 2002-03-25 2006-07-19 Sanochemia Pharmazeutika Aktiengesellschaft Verfahren zur Herstellung von Norgalanthamin, Ihren Isomeren, Salzen und Hydraten
EP1667769A2 (de) * 2003-09-29 2006-06-14 Sanochemia Pharmazeutica Aktiengesellschaft Verwendung von galanthamin und seinen derivaten zum herstellen von arzneimitteln
AT414125B (de) * 2003-09-29 2006-09-15 Sanochemia Pharmazeutika Ag Neue derivate des 4a,5,9,10,11,12-hexahydro- benzofuro(3a,3,2)(2) benzazepin, verfahren zu deren herstellung sowie deren verwendung zur herstellung von arzneimitteln
WO2005065662A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Solid dosage formulations of galantamine
WO2005065661A2 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Immediate, controlled and sustained release formulations of galanthamine
EP2316437B1 (en) * 2005-05-13 2014-07-30 Alza Corporation Multilayer drug delivery system with barrier against reservoir material flow
WO2007035941A2 (en) * 2005-09-23 2007-03-29 Alza Corporation Transdermal galantamine delivery system
CN102149398B (zh) * 2008-09-11 2013-12-04 I·B·R·以色列生物科技研究有限公司 雪片莲属鳞茎提取物及其用途
CN102573848A (zh) * 2009-04-24 2012-07-11 济州大学校产学协力团 含有去甲加兰他敏化合物作为活性成分的用于预防和治疗脱发症的组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663318A (en) * 1986-01-15 1987-05-05 Bonnie Davis Method of treating Alzheimer's disease
US4735169A (en) * 1986-09-03 1988-04-05 Nordson Corporation Adhesive applicator assembly
AU632458B2 (en) * 1987-05-04 1993-01-07 Bonnie Davis Compounds for the treatment of alzheimer's disease
US5336675A (en) * 1991-05-14 1994-08-09 Ernir Snorrason Method of treating mania in humans
US6323195B1 (en) * 1993-10-15 2001-11-27 Aventis Pharmaceuticals Inc. Galanthamine derivatives as acetylcholinesterase inhibitors
US5428159A (en) * 1994-04-08 1995-06-27 Ciba-Geigy Corporation Method of manufacture of (-)-galanthamine in high yield and purity substantially free of epigalanthamine

Also Published As

Publication number Publication date
WO1997003987A1 (fr) 1997-02-06
AU6662396A (en) 1997-02-18
NO980215D0 (no) 1998-01-16
DK0839149T3 (da) 2004-08-09
MX9800407A (es) 1998-04-30
ATE264332T1 (de) 2004-04-15
EP0839149A1 (fr) 1998-05-06
EP0839149B1 (fr) 2004-04-14
PT839149E (pt) 2004-08-31
JP4177894B2 (ja) 2008-11-05
JPH11509541A (ja) 1999-08-24
EP0839149B9 (fr) 2005-03-09
NO980215L (no) 1998-01-16
GB9514821D0 (en) 1995-09-20
US5958903A (en) 1999-09-28
CA2227235A1 (fr) 1997-02-06
IL122739A0 (en) 1998-08-16
CA2227235C (fr) 2010-08-31
ES2218596T3 (es) 2004-11-16
DE69632194T2 (de) 2005-03-17
DE69632194D1 (de) 2004-05-19

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