EP0813415A4 - Thionophosphate derivatives, process for their preparation and pharmaceutical compositions containing them - Google Patents
Thionophosphate derivatives, process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- EP0813415A4 EP0813415A4 EP95942875A EP95942875A EP0813415A4 EP 0813415 A4 EP0813415 A4 EP 0813415A4 EP 95942875 A EP95942875 A EP 95942875A EP 95942875 A EP95942875 A EP 95942875A EP 0813415 A4 EP0813415 A4 EP 0813415A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- thionophosphate
- derivatives
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
- C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
- C07F9/2458—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aliphatic amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL11179794A IL111797A0 (en) | 1994-11-28 | 1994-11-28 | Thionophosphate derivatives, process for their preparation and pharmaceutical compositions containing them |
IL11179794 | 1994-11-28 | ||
PCT/US1995/015199 WO1996016663A1 (en) | 1994-11-28 | 1995-11-13 | Thionophosphate derivatives, process for their preparation and pharmaceutical compositions containing them |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0813415A1 EP0813415A1 (en) | 1997-12-29 |
EP0813415A4 true EP0813415A4 (en) | 1998-05-06 |
Family
ID=11066823
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP95942875A Withdrawn EP0813415A4 (en) | 1994-11-28 | 1995-11-13 | Thionophosphate derivatives, process for their preparation and pharmaceutical compositions containing them |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0813415A4 (en) |
AU (1) | AU4408196A (en) |
CA (1) | CA2206374A1 (en) |
IL (1) | IL111797A0 (en) |
WO (1) | WO1996016663A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10051983A1 (en) * | 2000-10-20 | 2002-06-13 | Beate Kehrel | Medicaments useful e.g. for preventing thrombosis, inhibiting transplant rejection or treating chronic inflammatory reactions comprises agents inhibiting binding of oxidized proteins to CD36, |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3670057A (en) * | 1969-11-10 | 1972-06-13 | Sumitomo Chemical Co | S(alkllthio ethyl) phosphorothioamidate |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3087955A (en) * | 1960-02-08 | 1963-04-30 | Dow Chemical Co | O-haloalkyl o-alkyl phosphoramidothioates |
US3251675A (en) * | 1961-12-28 | 1966-05-17 | Dow Chemical Co | Method of inhibiting plant growth |
US3207661A (en) * | 1963-01-11 | 1965-09-21 | American Agricultural Chem Co | Bis-(aziridinyl)-phosphinothioic esters as chemical sterilants for insects and mites |
US3531550A (en) * | 1965-08-12 | 1970-09-29 | Monsanto Co | Phosphorus ester amides |
US3597476A (en) * | 1968-12-04 | 1971-08-03 | Dow Chemical Co | Process for preparing tris (2-mercaptoethylamino) phophine oxides and sulfides |
FR2034207A1 (en) * | 1969-02-20 | 1970-12-11 | Pepro |
-
1994
- 1994-11-28 IL IL11179794A patent/IL111797A0/en unknown
-
1995
- 1995-11-13 EP EP95942875A patent/EP0813415A4/en not_active Withdrawn
- 1995-11-13 WO PCT/US1995/015199 patent/WO1996016663A1/en not_active Application Discontinuation
- 1995-11-13 CA CA002206374A patent/CA2206374A1/en not_active Abandoned
- 1995-11-13 AU AU44081/96A patent/AU4408196A/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3670057A (en) * | 1969-11-10 | 1972-06-13 | Sumitomo Chemical Co | S(alkllthio ethyl) phosphorothioamidate |
Non-Patent Citations (12)
Title |
---|
CHEMICAL ABSTRACTS, vol. 071, no. 1, 7 July 1969, Columbus, Ohio, US; abstract no. 003242, KAS'YANOVA E F ET AL: "Synthesis of some derivatives of monothiophosphoric acid for the flotation of ores of heavy nonferrous metals" XP002055305 * |
CHEMICAL ABSTRACTS, vol. 085, no. 17, 25 October 1976, Columbus, Ohio, US; abstract no. 123267, MANDEL'BAUM Y A ET AL: "Reaction of phosphorus thio acid chlorides with ethanolamine" XP002055307 * |
CHEMICAL ABSTRACTS, vol. 092, no. 13, 31 March 1980, Columbus, Ohio, US; abstract no. 110472, KRONGAUZ Y I ET AL: "Reaction of thiophosphoric acid chlorides with ethanolamine" XP002055306 * |
CHEMICAL ABSTRACTS, vol. 121, no. 9, 29 August 1994, Columbus, Ohio, US; abstract no. 109001, GUO D ET AL: "N-substituted-O,O-diethylphosphoramidothioates" XP002055304 * |
GUO D ET AL: "Phase transfer catalytic synthesis of O,O-diethyl-N-hydrocarbyl phosphoramidothioates", POLYM. MATER. SCI. ENG. (PMSEDG,07430515);93; VOL.69,; PP.482-3, SHANDONG TEACHER'S UNIV.;DEP. OF CHEMISTRY; JINAN; 250014; PEOP. REP. CHINA (CN), XP002055302 * |
HECHENG HUAXUE (HEHUE2);94; VOL.2 (2); PP.185-9, SHANDONG NORMAL UNIV.;DEP. CHEM.; JINAN; 250014; PEOP. REP. CHINA (CN) * |
KELNER M.J.: "Thioureas react with superoxide radicals to yield a sulfhydril compound", JOURNAL OF BIOLOGICAL CHEMISTRY., vol. 265, no. 3, 1990, MD US, pages 1306 - 1311, XP002057035 * |
NOV. KHIM. SREDSTVA ZASHCH. RAST. (42DUA7);79; PP.11-15, USSR * |
See also references of WO9616663A1 * |
TIROSH O ET AL: "Antioxidant properties of amidothionophosphates: novel antioxidant molecules", FREE RADICAL BIOL. MED. (FRBMEH,08915849);96; VOL.20 (3); PP.421-32, HEBREW UNIV. JERUSALEM;DEP. PHARM.; JERUSALEM; ISRAEL (IL), XP002055303 * |
ZH. OBSHCH. KHIM. (ZOKHA4);69; VOL.39 (2); PP.365-6, USSR * |
ZH. OBSHCH. KHIM. (ZOKHA4);76; VOL.46 (8); PP.1757-8, USSR * |
Also Published As
Publication number | Publication date |
---|---|
CA2206374A1 (en) | 1996-06-06 |
IL111797A0 (en) | 1995-01-24 |
AU4408196A (en) | 1996-06-19 |
WO1996016663A1 (en) | 1996-06-06 |
EP0813415A1 (en) | 1997-12-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19970619 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 19980319 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE |
|
17Q | First examination report despatched |
Effective date: 20000821 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20010301 |