ZA941786B - Sulfonate and carbamate derivatives of 3-aroylbenzo(b)thiophenes - Google Patents

Sulfonate and carbamate derivatives of 3-aroylbenzo(b)thiophenes

Info

Publication number
ZA941786B
ZA941786B ZA941786A ZA941786A ZA941786B ZA 941786 B ZA941786 B ZA 941786B ZA 941786 A ZA941786 A ZA 941786A ZA 941786 A ZA941786 A ZA 941786A ZA 941786 B ZA941786 B ZA 941786B
Authority
ZA
South Africa
Prior art keywords
aroylbenzo
thiophenes
sulfonate
carbamate derivatives
compounds
Prior art date
Application number
ZA941786A
Other languages
English (en)
Inventor
Larry John Black
Henry Uhlman Bryant
George Joseph Cullinan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA941786B publication Critical patent/ZA941786B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA941786A 1993-03-19 1994-03-14 Sulfonate and carbamate derivatives of 3-aroylbenzo(b)thiophenes ZA941786B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/035,121 US5482949A (en) 1993-03-19 1993-03-19 Sulfonate derivatives of 3-aroylbenzo[b]thiophenes

Publications (1)

Publication Number Publication Date
ZA941786B true ZA941786B (en) 1995-09-14

Family

ID=21880778

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA941786A ZA941786B (en) 1993-03-19 1994-03-14 Sulfonate and carbamate derivatives of 3-aroylbenzo(b)thiophenes

Country Status (22)

Country Link
US (5) US5482949A (pt)
EP (1) EP0617030B1 (pt)
JP (1) JPH06321937A (pt)
CN (1) CN1097420A (pt)
AT (1) ATE180479T1 (pt)
AU (1) AU670177B2 (pt)
BR (1) BR9401183A (pt)
CZ (1) CZ57894A3 (pt)
DE (1) DE69418639T2 (pt)
DK (1) DK0617030T3 (pt)
ES (1) ES2132339T3 (pt)
FI (1) FI941262A (pt)
GR (1) GR3030317T3 (pt)
HU (1) HUT70549A (pt)
IL (1) IL108958A0 (pt)
NO (1) NO940940L (pt)
NZ (1) NZ260085A (pt)
PH (1) PH30177A (pt)
SI (1) SI0617030T1 (pt)
TW (1) TW304953B (pt)
YU (1) YU12794A (pt)
ZA (1) ZA941786B (pt)

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US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US5770609A (en) 1993-01-28 1998-06-23 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5482949A (en) * 1993-03-19 1996-01-09 Eli Lilly And Company Sulfonate derivatives of 3-aroylbenzo[b]thiophenes
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US5482950A (en) * 1993-10-15 1996-01-09 Eli Lilly And Company Methods for lowering serum cholesterol
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JPH09507071A (ja) * 1993-12-21 1997-07-15 イーライ・リリー・アンド・カンパニー アミロイド原性ペプチドに関連した状態を治療又は予防する方法
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US5552412A (en) 1995-01-09 1996-09-03 Pfizer Inc 5-substitued-6-cyclic-5,6,7,8-tetrahydronaphthalen2-ol compounds which are useful for treating osteoporosis
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US6479517B1 (en) 1995-02-28 2002-11-12 Eli Lilly And Company Phosphorous-containing benzothiophenes
US6451817B1 (en) 1995-03-10 2002-09-17 Eli Lilly And Company Alpha-substituted-1-benzyl-napthyls
US6653328B1 (en) 1995-03-10 2003-11-25 Eli Lilly And Company 3-benzyl-benzothiophenes
US5622974A (en) * 1995-03-10 1997-04-22 Eli Lilly And Company α-substituted-3-benzyl-benzofurans
US6384053B1 (en) 1995-03-10 2002-05-07 Eli Lilly And Company α-substituted-1-benzyl-napthyls
US6417199B1 (en) 1995-03-10 2002-07-09 Eli Lilly And Company 3-benzyl-benzothiophenes
US6395755B1 (en) * 1995-03-10 2002-05-28 Eli Lilly And Company Benzothiophene pharmaceutical compounds
US5705507A (en) * 1995-03-10 1998-01-06 Eli Lilly And Company Aplha-substituted-3-benzyl-benzofurans
US5523309A (en) * 1995-03-10 1996-06-04 Eli Lilly And Company Benzofuran pharmaceutical compounds
US6391892B1 (en) * 1995-03-10 2002-05-21 Eli Lilly And Company Naphthyl pharmaceutical compounds
US5514704A (en) * 1995-03-13 1996-05-07 Eli Lilly And Company Benzothiophenes to inhibit leukotrienes
US5532382A (en) * 1995-03-13 1996-07-02 Eli Lilly And Company Benzothiophenes substituted at the 3-carbonyl
US5514703A (en) * 1995-03-13 1996-05-07 Eli Lilly And Company Benzothiophene compounds useful for inhibiting lipoxygenase
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US5837313A (en) * 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
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IL125863A (en) * 1996-02-22 2000-10-31 Lilly Co Eli Benzothiophenes and formulations containing same
IL120266A (en) * 1996-02-28 2005-05-17 Pfizer Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions
US5688796A (en) * 1996-03-12 1997-11-18 Eli Lilly And Company Heterocyclic substituted benzothiophenes, compositions, and methods
IL126320A (en) * 1996-03-26 2001-08-08 Lilly Co Eli Reloxifen and pharmaceuticals containing it
US5843984A (en) * 1996-05-09 1998-12-01 Eli Lilly And Company Sulfated benzothiophene derivatives, methods of use and formulations containing same
KR20000022040A (ko) * 1996-06-20 2000-04-25 보오드 오브 리젠츠, 더 유니버시티 오브 텍사스 시스템 약학적 활성 제제를 제공하기 위한 화합물, 방법 및 그의 용도
CA2206752A1 (en) * 1996-07-02 1998-01-02 George Joseph Cullinan Benzothiophene compounds, intermediates, processes, and methods of use
CA2206997A1 (en) * 1996-07-10 1998-01-10 Eli Lilly And Company Benzothiophene compounds and methods of use
NZ333839A (en) * 1996-08-28 2001-06-29 Lilly Co Eli Amorphous benzothiophenes
CA2213810C (en) * 1996-08-29 2006-06-06 Lewis Dale Pennington Benzo¬b|thiophene compounds, intermediates, processes, compositions and methods
CA2214072C (en) * 1996-08-29 2006-11-14 Eli Lilly And Company Benzo [b] thiophene compounds, intermediates, processes, compositions, and methods
CA2214922A1 (en) * 1996-09-27 1998-03-27 Eli Lilly And Company Benzothiophene compounds, compositions, and methods
US5948796A (en) * 1996-10-10 1999-09-07 Eli Lilly And Company Benzo B!thiophene compounds, intermediates, formulations, and methods
CA2217373A1 (en) * 1996-10-10 1998-04-10 Michael John Martin Benzo¬b|thiophene compounds, intermediates, formulations, and methods
JPH10204082A (ja) * 1996-10-25 1998-08-04 Eli Lilly & Co 選択的エストロゲンレセプターモジュレーターとしての活性を有する置換されたベンゾ［ｂ］チオフェン化合物
AU6959898A (en) * 1997-04-11 1998-11-11 David J. Grainger Compounds and therapies for the prevention of vascular and non-vascular pathol ogies
US6025373A (en) * 1997-04-22 2000-02-15 Eli Lilly And Company Methods for reducing fibrinogen
JP2001522373A (ja) 1997-04-30 2001-11-13 イーライ・リリー・アンド・カンパニー 抗血栓剤
CA2236254A1 (en) * 1997-04-30 1998-10-30 David Warren Hoard Process for preparing benzo¬b|thiophenes
CA2231013A1 (en) * 1997-04-30 1998-10-30 Eli Lilly And Company Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceuticals
AU7274098A (en) 1997-04-30 1998-11-24 Eli Lilly And Company Antithrombotic agents
EP0979076A4 (en) * 1997-04-30 2003-03-19 Lilly Co Eli INTERMEDIATES AND PROCESSES FOR THE PREPARATION OF BENZO b] THIOPHENES
JP2001522372A (ja) * 1997-04-30 2001-11-13 イーライ・リリー・アンド・カンパニー ベンゾチオフェンの製造方法
AU7261598A (en) * 1997-04-30 1998-11-24 Eli Lilly And Company Intermediates and a process for preparing benzo{b}thiophenes
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CN1254280A (zh) * 1997-04-30 2000-05-24 伊莱利利公司 用于制备取代的苯并[b]噻吩的区域选择性烷基化方法
US6008232A (en) * 1997-08-20 1999-12-28 Eli Lilly And Company Methods for preventing headaches
US6103740A (en) * 1997-08-21 2000-08-15 Eli Lilly And Company Methods for lowering platelet counts
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FR2777784B1 (fr) * 1998-04-27 2004-03-19 Arepa Composition pharmaceutique a base d'estrogene et de progesterone
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DK0997460T3 (da) * 1998-10-28 2003-03-31 Lilly Co Eli Benzothiophenforbindelser som antithrombotiske midler og mellemprodukter
FR2813308B1 (fr) * 2000-08-23 2005-07-01 Sanofi Synthelabo Aminoalkoxybenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation ainsi que les compositions les contenant
FR2813306B1 (fr) 2000-08-23 2005-10-21 Sanofi Synthelabo Aminoalkybenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant
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JP3804824B2 (ja) * 2001-09-19 2006-08-02 ヤマハ株式会社 ディジタルミキサ
JP4665805B2 (ja) * 2006-03-17 2011-04-06 カシオ計算機株式会社 印字装置

Also Published As

Publication number Publication date
HU9400774D0 (en) 1994-06-28
NZ260085A (en) 1995-12-21
TW304953B (pt) 1997-05-11
US5994371A (en) 1999-11-30
PH30177A (en) 1997-01-21
AU670177B2 (en) 1996-07-04
US5482949A (en) 1996-01-09
DK0617030T3 (da) 1999-11-08
FI941262A (fi) 1994-09-20
ATE180479T1 (de) 1999-06-15
US5798351A (en) 1998-08-25
US5605924A (en) 1997-02-25
BR9401183A (pt) 1994-11-01
CN1097420A (zh) 1995-01-18
GR3030317T3 (en) 1999-09-30
ES2132339T3 (es) 1999-08-16
EP0617030A1 (en) 1994-09-28
DE69418639T2 (de) 1999-10-07
JPH06321937A (ja) 1994-11-22
CZ57894A3 (en) 1994-12-15
DE69418639D1 (de) 1999-07-01
US5599833A (en) 1997-02-04
AU5786394A (en) 1994-09-22
NO940940L (no) 1994-09-20
SI0617030T1 (en) 1999-10-31
YU12794A (sh) 1997-01-08
EP0617030B1 (en) 1999-05-26
FI941262A0 (fi) 1994-03-17
IL108958A0 (en) 1994-06-24
HUT70549A (en) 1995-10-30
NO940940D0 (no) 1994-03-16

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