ZA941522B - New 4-aminopyridines - processes for their production as well as pharmaceutical agents containing them - Google Patents

New 4-aminopyridines - processes for their production as well as pharmaceutical agents containing them

Info

Publication number
ZA941522B
ZA941522B ZA941522A ZA941522A ZA941522B ZA 941522 B ZA941522 B ZA 941522B ZA 941522 A ZA941522 A ZA 941522A ZA 941522 A ZA941522 A ZA 941522A ZA 941522 B ZA941522 B ZA 941522B
Authority
ZA
South Africa
Prior art keywords
aminopyridines
processes
new
production
well
Prior art date
Application number
ZA941522A
Other languages
English (en)
Inventor
Herbert Leinert
Thomas Poll
Wolfgang Von Der Saal
Karlheinz Stegmeier
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of ZA941522B publication Critical patent/ZA941522B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
ZA941522A 1993-03-05 1994-03-04 New 4-aminopyridines - processes for their production as well as pharmaceutical agents containing them ZA941522B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4306873A DE4306873A1 (de) 1993-03-05 1993-03-05 Neue 4-Aminopyridine-Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
ZA941522B true ZA941522B (en) 1995-09-04

Family

ID=6481990

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA941522A ZA941522B (en) 1993-03-05 1994-03-04 New 4-aminopyridines - processes for their production as well as pharmaceutical agents containing them

Country Status (8)

Country Link
EP (1) EP0687254A1 (de)
JP (1) JPH08509472A (de)
AU (1) AU6282494A (de)
CA (1) CA2157215A1 (de)
DE (1) DE4306873A1 (de)
IL (1) IL108847A0 (de)
WO (1) WO1994020468A1 (de)
ZA (1) ZA941522B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL115420A0 (en) 1994-09-26 1995-12-31 Zeneca Ltd Aminoheterocyclic derivatives
US5559150A (en) * 1995-06-06 1996-09-24 3-Dimensional Pharmaceuticals, Inc. N,N-disulfonylated aminobenzene carboxlic acids and the use thereof as thrombin inhibitors
US5741819A (en) * 1995-06-07 1998-04-21 3-Dimensional Pharmaceuticals, Inc. Arylsulfonylaminobenzene derivatives and the use thereof as factor Xa inhibitors
GB9602166D0 (en) * 1996-02-02 1996-04-03 Zeneca Ltd Aminoheterocyclic derivatives
WO1997028128A1 (en) 1996-02-02 1997-08-07 Zeneca Limited Heterocyclic compounds useful as pharmaceutical agents
CA2260872A1 (en) * 1996-08-14 1998-02-19 Elaine Sophie Elizabeth Stokes Substituted pyrimidine derivatives and their pharmaceutical use
UA56197C2 (uk) 1996-11-08 2003-05-15 Зенека Лімітед Гетероциклічні похідні
US6440972B1 (en) 1997-02-13 2002-08-27 Zeneca Limited Heterocyclic compounds useful as oxido-squalene cyclase inhibitors
GB9715895D0 (en) * 1997-07-29 1997-10-01 Zeneca Ltd Heterocyclic compounds
WO1999016750A1 (en) * 1997-09-30 1999-04-08 Merck & Co., Inc. Thrombin inhibitors
GB9902989D0 (en) 1999-02-11 1999-03-31 Zeneca Ltd Heterocyclic derivatives
WO2004076434A1 (en) * 2003-02-28 2004-09-10 Aic Dipeptidyl peptidase inhibitors
CN113429341A (zh) * 2016-09-18 2021-09-24 正大天晴药业集团股份有限公司 新型衣壳蛋白装配抑制剂

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD235866B1 (de) * 1985-03-29 1988-12-28 Univ Leipzig Verfahren zur herstellung von n alpha (2-naphthyl)-sulfonylaminoacylierten amidinophenylalanisamiden

Also Published As

Publication number Publication date
JPH08509472A (ja) 1996-10-08
IL108847A0 (en) 1994-06-24
EP0687254A1 (de) 1995-12-20
WO1994020468A1 (de) 1994-09-15
CA2157215A1 (en) 1994-09-15
AU6282494A (en) 1994-09-26
DE4306873A1 (de) 1994-09-08

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