ZA929161B - Microcrystalline cellulose spheronization composition. - Google Patents

Microcrystalline cellulose spheronization composition.

Info

Publication number
ZA929161B
ZA929161B ZA929161A ZA929161A ZA929161B ZA 929161 B ZA929161 B ZA 929161B ZA 929161 A ZA929161 A ZA 929161A ZA 929161 A ZA929161 A ZA 929161A ZA 929161 B ZA929161 B ZA 929161B
Authority
ZA
South Africa
Prior art keywords
composition
microcrystalline cellulose
hydrocolloid
spheronization
sphericity
Prior art date
Application number
ZA929161A
Other languages
English (en)
Inventor
David Frank Erkoboni
Scott Allan Fiore
Thomas Alonzo Wheatley
Original Assignee
Fmc Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fmc Corp filed Critical Fmc Corp
Publication of ZA929161B publication Critical patent/ZA929161B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/005—Processes for mixing polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/02—Cellulose; Modified cellulose
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2300/00—Characterised by the use of unspecified polymers
    • C08J2300/14—Water soluble or water swellable polymers, e.g. aqueous gels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2301/00—Characterised by the use of cellulose, modified cellulose or cellulose derivatives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/26—Cellulose ethers
    • C08L1/28—Alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
ZA929161A 1991-12-30 1992-11-25 Microcrystalline cellulose spheronization composition. ZA929161B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81602791A 1991-12-30 1991-12-30

Publications (1)

Publication Number Publication Date
ZA929161B true ZA929161B (en) 1993-05-25

Family

ID=25219497

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA929161A ZA929161B (en) 1991-12-30 1992-11-25 Microcrystalline cellulose spheronization composition.

Country Status (16)

Country Link
US (1) US5725886A (zh)
EP (1) EP0619731B1 (zh)
JP (1) JP2628230B2 (zh)
CN (1) CN1074228A (zh)
AT (1) ATE196733T1 (zh)
AU (1) AU663146B2 (zh)
BR (1) BR9206996A (zh)
CA (1) CA2126441C (zh)
DE (1) DE69231499T2 (zh)
ES (1) ES2150438T3 (zh)
FI (1) FI943121A (zh)
IL (1) IL104087A (zh)
MX (1) MX9207438A (zh)
NO (1) NO942457L (zh)
WO (1) WO1993012768A1 (zh)
ZA (1) ZA929161B (zh)

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US5567439A (en) * 1994-06-14 1996-10-22 Fuisz Technologies Ltd. Delivery of controlled-release systems(s)
US5585115A (en) 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
US6471994B1 (en) 1995-01-09 2002-10-29 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US6936277B2 (en) 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
IL139728A (en) * 1995-01-09 2003-06-24 Penwest Pharmaceuticals Compan Aqueous slurry composition containing microcrystalline cellulose for preparing a pharmaceutical excipient
US6395303B1 (en) 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
US6391337B2 (en) 1995-11-15 2002-05-21 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US6852336B2 (en) 1995-11-15 2005-02-08 J. Rettenmaier & Soehne Gmbh + Co. Kg Directly compressible high load acetaminophen formulations
US5733578A (en) * 1995-11-15 1998-03-31 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
SI0948318T1 (en) * 1996-08-14 2004-08-31 Yamanouchi Europe B.V. Granulates comprising a water soluble compound and cellulose
CN1086189C (zh) * 1997-06-12 2002-06-12 食品机械和化工公司 超细微晶纤维素组合物及其制备方法
US5904937A (en) * 1997-10-03 1999-05-18 Fmc Corporation Taste masked pharmaceutical compositions
US7122207B2 (en) * 1998-05-22 2006-10-17 Bristol-Myers Squibb Company High drug load acid labile pharmaceutical composition
AU777415B2 (en) 1999-09-29 2004-10-14 R.P. Scherer Technologies, Inc. Hydrolyzed cellulose granulations of salts of drugs
GEP20043285B (en) 2000-03-30 2004-07-26 Bristol Myers Squibb Co Sustained Release Beadlets Containing Stavudine, Method for Their Production, Pharmaceutical Composition Containing the Same and Use Thereof for Treatment Retroviral Infections
US20040213839A1 (en) * 2001-02-05 2004-10-28 Andrew Favara Methods and compositions for reducing the taste of pharmaceutically active agents
MXPA03009676A (es) * 2001-04-26 2004-02-12 Bristol Myers Squibb Co CONTROL DE COMPACTIBILIDAD A TRAVeS DE CRISTALIZACION.
EP1575487B1 (en) 2002-05-14 2019-08-14 DuPont Nutrition USA, Inc. Coattrited microcrystalline cellulose hydrocolloid compositions and method for manufacture
EP1848292B1 (en) * 2005-02-04 2015-10-14 Philip Morris Products S.A. Cigarette and filter with cellulosic flavor addition
US20070000505A1 (en) * 2005-02-24 2007-01-04 Philip Morris Usa Inc. Smoking article with tobacco beads
US7879382B2 (en) * 2005-09-30 2011-02-01 Fmc Corporation Stabilizers and compositions and products comprising same
FR2898056B1 (fr) * 2006-03-01 2012-01-20 Ethypharm Sa Comprimes resistant a l'ecrasement destines a eviter le detournement illicite
NZ574427A (en) * 2006-07-28 2011-11-25 Zaklady Farmaceutyczne Polpharma S A Extended release pharmaceutical formulation of metoprolol and process for its preparation
WO2008057266A2 (en) * 2006-10-27 2008-05-15 Fmc Corporation Dry granulation binders, products, and use thereof
CN101652128B (zh) * 2007-03-02 2012-12-19 法纳姆公司 使用蜡状材料的缓释组合物
US9888712B2 (en) 2007-06-08 2018-02-13 Philip Morris Usa Inc. Oral pouch products including a liner and tobacco beads
MY164765A (en) * 2007-10-10 2018-01-30 Avantor Performance Mat Llc Directly compressible high functionality granular microcrystalline cellulose based excipient, manufacturing process and use thereof
US20100055180A1 (en) * 2007-10-10 2010-03-04 Mallinckrodt Baker, Inc. Directly Compressible Granular Microcrystalline Cellulose Based Excipient, Manufacturing Process and Use Thereof
SG171752A1 (en) * 2008-11-19 2011-07-28 Avantor Performance Mat Inc Directly compressible granular microcrystalline cellulose based excipient, manufacturing process and use thereof
US9144625B2 (en) 2008-11-27 2015-09-29 Speciality Fibres And Materials Ltd. Cellulose ethylsulfonate-based absorbent material
US9221963B2 (en) 2008-11-27 2015-12-29 Speciality Fibres And Materials Ltd. Absorbent material
US8377215B2 (en) 2008-12-18 2013-02-19 Philip Morris Usa Inc. Moist botanical pouch processing
US8863755B2 (en) * 2009-02-27 2014-10-21 Philip Morris Usa Inc. Controlled flavor release tobacco pouch products and methods of making
US10051884B2 (en) 2010-03-26 2018-08-21 Philip Morris Usa Inc. Controlled release mentholated tobacco beads
US20110277781A1 (en) 2010-03-26 2011-11-17 Philip Morris Usa Inc. Methods for improving quality of mainstream smoke and multicomponent filters and smoking articles therefor
JP6188030B2 (ja) 2011-10-05 2017-08-30 エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ 微結晶セルロースおよびカルボキシメチルセルロースの安定化剤組成物、該組成物の製造方法並びに食品製品
CN103857739B (zh) 2011-10-05 2017-04-19 Fmc有限公司 共磨碎微晶纤维素和羧甲基纤维素的稳定剂组合物、制备方法和应用
CN104010522A (zh) 2011-12-09 2014-08-27 Fmc有限公司 共磨碎稳定剂组合物
CN105085992B (zh) * 2015-09-16 2017-12-29 珠海市东辰医药科技有限公司 一种改性微晶纤维素的制备工艺
CN105193738B (zh) * 2015-09-21 2018-09-04 珠海市东辰制药有限公司 一种微晶纤维素丸芯的制备工艺
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1010477A (en) * 1962-05-15 1965-11-17 Fmc Corp Method of making cellulose crystallite aggregates in particulate form and product of such method
GB1561204A (en) * 1977-06-01 1980-02-13 Ici Ltd Sustained release pharmaceutical composition
US4421778A (en) * 1982-11-04 1983-12-20 Rich Products Corporation Freezer stable whipped ice cream and milk shake food products
US4744987A (en) * 1985-03-08 1988-05-17 Fmc Corporation Coprocessed microcrystalline cellulose and calcium carbonate composition and its preparation
IL81419A0 (en) * 1986-01-30 1987-08-31 Syntex Inc Long acting sustained release pharmaceutical compositions containing dihydropyridines and their preparation
GB8705083D0 (en) * 1987-03-04 1987-04-08 Euro Celtique Sa Spheroids
CA1323833C (en) * 1987-04-28 1993-11-02 Yatindra M. Joshi Pharmaceutical compositions in the form of beadlets and method
US4837030A (en) * 1987-10-06 1989-06-06 American Cyanamid Company Novel controlled release formulations of tetracycline compounds

Also Published As

Publication number Publication date
NO942457D0 (no) 1994-06-29
EP0619731A1 (en) 1994-10-19
CN1074228A (zh) 1993-07-14
BR9206996A (pt) 1995-12-05
DE69231499D1 (de) 2000-11-09
NO942457L (no) 1994-06-29
EP0619731A4 (en) 1995-05-03
CA2126441C (en) 1999-12-21
IL104087A0 (en) 1993-05-13
DE69231499T2 (de) 2001-05-03
FI943121A0 (fi) 1994-06-29
AU663146B2 (en) 1995-09-28
WO1993012768A1 (en) 1993-07-08
ATE196733T1 (de) 2000-10-15
IL104087A (en) 1998-10-30
US5725886A (en) 1998-03-10
JPH06511255A (ja) 1994-12-15
EP0619731B1 (en) 2000-10-04
MX9207438A (es) 1993-06-01
FI943121A (fi) 1994-06-29
ES2150438T3 (es) 2000-12-01
JP2628230B2 (ja) 1997-07-09
CA2126441A1 (en) 1993-07-08
AU3179393A (en) 1993-07-28

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