ZA905978B - Derivatives of 1,2,3,4-tetrahydro-9-acridinamine - Google Patents

Derivatives of 1,2,3,4-tetrahydro-9-acridinamine

Info

Publication number
ZA905978B
ZA905978B ZA905978A ZA905978A ZA905978B ZA 905978 B ZA905978 B ZA 905978B ZA 905978 A ZA905978 A ZA 905978A ZA 905978 A ZA905978 A ZA 905978A ZA 905978 B ZA905978 B ZA 905978B
Authority
ZA
South Africa
Prior art keywords
acridinamine
tetrahydro
derivatives
agents
cerebral
Prior art date
Application number
ZA905978A
Other languages
English (en)
Inventor
Colin Granger
Granger Colin
Walter Hamilton Moos
Hamilton Moos Walter
Jeffrey Alan Kester
Alan Kester Jeffrey
Anthony Jerome Thomas
Jerome Thomas Anthony
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ZA905978B publication Critical patent/ZA905978B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
ZA905978A 1989-07-31 1990-07-30 Derivatives of 1,2,3,4-tetrahydro-9-acridinamine ZA905978B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/387,722 US4999430A (en) 1989-07-31 1989-07-31 Derivatives of 1,2,3,4-tetrahydro-9-acrisinamine

Publications (1)

Publication Number Publication Date
ZA905978B true ZA905978B (en) 1992-04-29

Family

ID=23531113

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA905978A ZA905978B (en) 1989-07-31 1990-07-30 Derivatives of 1,2,3,4-tetrahydro-9-acridinamine

Country Status (17)

Country Link
US (1) US4999430A (da)
EP (2) EP0628548B1 (da)
JP (1) JP2930245B2 (da)
KR (1) KR910002802A (da)
AT (2) ATE119885T1 (da)
AU (1) AU5994590A (da)
CA (1) CA2022297C (da)
DE (2) DE69033369T2 (da)
DK (2) DK0411534T3 (da)
ES (2) ES2068955T3 (da)
FI (1) FI903752A0 (da)
GR (1) GR3032539T3 (da)
IE (1) IE66823B1 (da)
NO (1) NO903359L (da)
NZ (1) NZ234672A (da)
PT (1) PT94849A (da)
ZA (1) ZA905978B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85741A (en) * 1987-03-17 1996-05-14 Hoechst Roussel Pharma Transformed Tetra-Hydroacridines Process for their preparation and pharmaceutical preparations containing A-amino-Tetra-Transformed Hydroacridines
FR2640508B1 (fr) * 1988-12-19 1994-07-01 Dietlin Francois Nouvelles compositions et nouveaux produits pharmaceutiques assurant la regeneration de leucocytes et leur emploi pour le traitement du syndrome immuno-deficitaire
JP2546919B2 (ja) * 1989-11-08 1996-10-23 三菱化学株式会社 ９ーアシルアミノテトラヒドロアクリジン誘導体
CA2029497C (en) * 1989-11-08 2002-06-04 Kunihiro Ninomiya (Deceased) 4-acylaminopyridine derivative
US5179100A (en) * 1992-03-09 1993-01-12 Hoechst-Roussel Pharmaceuticals Inc. 4,5-dihydropyrazolo[3,4-a]acridines
US5422350A (en) * 1992-09-10 1995-06-06 Warner-Lambert Company Nitrogen substituted acridine and cytochrome P450 inhibitors and methods of use
US5466696A (en) * 1992-09-10 1995-11-14 Warner Lambert Company Tacrine and cytochrome P450 oxidase inhibitors and methods of use
HU213107B (en) * 1994-02-23 1997-02-28 Egyt Gyogyszervegyeszeti Gyar Process for producing acetic acid derivatives and pharmaceutical compositions containing them
GB9716879D0 (en) * 1997-08-08 1997-10-15 Shire Int Licensing Bv Treatment of attention deficit disorders
US6218383B1 (en) 1998-08-07 2001-04-17 Targacept, Inc. Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
ES2168926B1 (es) * 1999-12-14 2003-10-16 Prous Science S A Derivados de ciclopenta- ciclohexa- y ciclohepta (b)quinoleina, procedimiento para su fabricacion, utilizacion y composicion farmaceutica correspondiente.
US20080045500A1 (en) * 2004-07-01 2008-02-21 Eisai R&D Management Co., Ltd. Nerve Regeneration Stimulator
CN1315810C (zh) * 2004-08-30 2007-05-16 北京理工大学 哌嗪桥联他克林双体衍生物及其合成方法
US20080188510A1 (en) * 2005-05-23 2008-08-07 Eisai R & D Management Co., Ltd. Novel methods using zonisamide
JP2013513588A (ja) * 2009-12-11 2013-04-22 ジーンコード エーエス Ｇｄｎｆファミリーリガンド（ｇｆｌ）のミメティックまたはｒｅｔシグナル経路活性化因子を用いた、神経系細胞の生存を容易にするための方法
CA2789014C (en) 2010-02-09 2019-01-15 Michela Gallagher Methods and compositions for improving cognitive function
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神***病を処置するための方法および組成物
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
CA2904767C (en) 2013-03-15 2022-06-21 Agenebio, Inc. Methods and compositions for improving cognitive function
WO2016191288A1 (en) 2015-05-22 2016-12-01 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4985430A (en) * 1987-12-03 1991-01-15 Mitsubishi Kasei Corporation 9-acylamino-tetrahydroacridine derivatives and memory enhancing agent containing said derivative as active ingredient

Also Published As

Publication number Publication date
ES2141787T3 (es) 2000-04-01
EP0628548A1 (en) 1994-12-14
AU5994590A (en) 1991-01-31
NO903359L (no) 1991-02-01
JP2930245B2 (ja) 1999-08-03
DE69017789T2 (de) 1995-07-13
JPH0366670A (ja) 1991-03-22
US4999430A (en) 1991-03-12
IE902751A1 (en) 1991-02-27
NO903359D0 (no) 1990-07-30
DK0628548T3 (da) 2000-05-08
EP0411534A3 (en) 1991-06-05
DK0411534T3 (da) 1995-07-24
FI903752A0 (fi) 1990-07-27
EP0411534B1 (en) 1995-03-15
DE69017789D1 (de) 1995-04-20
DE69033369D1 (de) 1999-12-30
GR3032539T3 (en) 2000-05-31
DE69033369T2 (de) 2000-05-11
NZ234672A (en) 1991-11-26
ES2068955T3 (es) 1995-05-01
IE66823B1 (en) 1996-02-07
PT94849A (pt) 1991-04-18
ATE186908T1 (de) 1999-12-15
KR910002802A (ko) 1991-02-26
CA2022297C (en) 2001-09-18
EP0411534A2 (en) 1991-02-06
ATE119885T1 (de) 1995-04-15
EP0628548B1 (en) 1999-11-24
CA2022297A1 (en) 1991-02-01

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