ZA879694B - Novel carbamoyloxylabdanes,intermediates and a process for the preparation thereof and their use as medicaments - Google Patents

Novel carbamoyloxylabdanes,intermediates and a process for the preparation thereof and their use as medicaments

Info

Publication number
ZA879694B
ZA879694B ZA879694A ZA879694A ZA879694B ZA 879694 B ZA879694 B ZA 879694B ZA 879694 A ZA879694 A ZA 879694A ZA 879694 A ZA879694 A ZA 879694A ZA 879694 B ZA879694 B ZA 879694B
Authority
ZA
South Africa
Prior art keywords
carbamoyloxylabdanes
medicaments
intermediates
novel
preparation
Prior art date
Application number
ZA879694A
Other languages
English (en)
Inventor
Walter Kosley Raymond
Joseph Cherill Robert
Original Assignee
Hoechst-Roussel Pharmaceuticals Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst-Roussel Pharmaceuticals Incorporated filed Critical Hoechst-Roussel Pharmaceuticals Incorporated
Publication of ZA879694B publication Critical patent/ZA879694B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D497/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA879694A 1986-12-29 1987-12-28 Novel carbamoyloxylabdanes,intermediates and a process for the preparation thereof and their use as medicaments ZA879694B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US94707086A 1986-12-29 1986-12-29

Publications (1)

Publication Number Publication Date
ZA879694B true ZA879694B (en) 1988-06-23

Family

ID=25485469

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA879694A ZA879694B (en) 1986-12-29 1987-12-28 Novel carbamoyloxylabdanes,intermediates and a process for the preparation thereof and their use as medicaments

Country Status (15)

Country Link
EP (2) EP0279948A1 (fr)
JP (2) JPH01501866A (fr)
KR (2) KR880007506A (fr)
AU (1) AU606639B2 (fr)
CA (1) CA1307530C (fr)
DK (2) DK687787A (fr)
FI (1) FI875699A (fr)
HU (3) HU204264B (fr)
IL (1) IL84955A0 (fr)
NO (1) NO875449L (fr)
NZ (1) NZ223051A (fr)
PH (1) PH24972A (fr)
PT (1) PT86470B (fr)
WO (1) WO1988005047A1 (fr)
ZA (1) ZA879694B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU591196B2 (en) * 1985-11-15 1989-11-30 Nippon Kayaku Kabushiki Kaisha Novel forskolin derivatives
US5846992A (en) * 1987-10-08 1998-12-08 Hoechst Marion Roussel, Inc. Synergistic intraocular pressure lowering combinations
US4902696A (en) * 1987-10-08 1990-02-20 Hoechst-Roussel Pharmaceuticals, Inc. Synergistic intraocular pressure lowering combinations
DE3737353A1 (de) * 1987-11-04 1989-05-18 Hoechst Ag Neue acyllabdan-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4883793A (en) * 1988-05-09 1989-11-28 Hoechst-Roussel Pharmaceuticals Inc. Hydrazinocarbonyloxylabdanes for treating cardiac failure
US5093336A (en) * 1989-07-06 1992-03-03 Hoechat-Roussel Pharmaceuticals, Inc. 6- and 7-deoxyforskolin and derivatives thereof
US5350864A (en) * 1990-05-03 1994-09-27 The United States Of America As Represented By The Department Of Health And Human Services Aminoalkylcarbamyl derivatives of forskolin as intermediates for the synthesis of useful forskolin derivatives
DE102005058526B4 (de) * 2005-12-08 2019-06-19 Robert Bosch Gmbh Zweistufiges Ventil zum Steuern von Fluiden

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0191166B1 (fr) * 1984-12-14 1991-02-06 Hoechst-Roussel Pharmaceuticals Incorporated Aminoacyllabdanes, procédé et intermédiaires pour leur préparation et leur utilisation comme médicaments
EP0193132B1 (fr) * 1985-03-01 1991-04-17 Hoechst-Roussel Pharmaceuticals Incorporated Dérivés de labdane, procédé pour leur préparation et leur usage comme médicaments
DE3623300A1 (de) * 1986-07-11 1988-01-21 Hoechst Ag 7-acyloxy-6-aminoacyloxypolyoxylabdane, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3730748A1 (de) * 1987-06-06 1988-12-22 Hoechst Ag Neue polyoxygenierte labdanderivate, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3740625A1 (de) * 1987-12-01 1989-06-15 Hoechst Ag Neue labdanderivate, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
HUT48613A (en) 1989-06-28
JPS63185974A (ja) 1988-08-01
DK479988D0 (da) 1988-08-26
FI875699A (fi) 1988-06-30
HU206875B (en) 1993-01-28
DK479988A (da) 1988-08-26
JPH01501866A (ja) 1989-06-29
KR880007506A (ko) 1988-08-27
EP0296225A1 (fr) 1988-12-28
DK687787D0 (da) 1987-12-28
AU606639B2 (en) 1991-02-14
IL84955A0 (en) 1988-06-30
AU8306987A (en) 1988-06-30
HU913584D0 (en) 1992-01-28
DK687787A (da) 1988-06-30
PT86470B (pt) 1991-02-08
WO1988005047A1 (fr) 1988-07-14
NO875449L (no) 1988-06-30
CA1307530C (fr) 1992-09-15
PT86470A (en) 1988-01-01
HU204264B (en) 1991-12-30
NO875449D0 (no) 1987-12-28
KR890700124A (ko) 1989-03-02
NZ223051A (en) 1990-06-26
FI875699A0 (fi) 1987-12-23
PH24972A (en) 1990-12-26
EP0279948A1 (fr) 1988-08-31

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