ZA847048B - 6-sulfoxyphenol derivatives,their preparation and their use as cytoprotective agents - Google Patents

6-sulfoxyphenol derivatives,their preparation and their use as cytoprotective agents

Info

Publication number: ZA847048B
Authority: ZA; South Africa
Prior art keywords: sulfoxyphenol; derivatives; preparation; alkyl; cytoprotective agents
Prior art date: 1983-09-10

Application number

ZA847048A

Other languages

English (en)

Inventor

Heinrich Christian Englert

Hans-Jochen Lang

Dieter Mania

Martin Bickel

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-09-10

Filing date

1984-09-07

Publication date

1985-04-24

1984-09-07 Application filed by Hoechst Ag filed Critical Hoechst Ag

1985-04-24 Publication of ZA847048B publication Critical patent/ZA847048B/xx

Links

230000001120 cytoprotective effect Effects 0.000 title abstract 2
MZPWKJZDOCIALD-UHFFFAOYSA-N pyrocatechol sulfate Chemical class OC1=CC=CC=C1OS(O)(=O)=O MZPWKJZDOCIALD-UHFFFAOYSA-N 0.000 title 1
WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 6
125000000217 alkyl group Chemical group 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
125000000753 cycloalkyl group Chemical group 0.000 abstract 2
125000004663 dialkyl amino group Chemical group 0.000 abstract 2
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000001841 imino group Chemical group [H]N=* 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C313/00—Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C313/02—Sulfinic acids; Derivatives thereof
- C07C313/04—Sulfinic acids; Esters thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/562—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom
- C07C45/565—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom by reaction with hexamethylene-tetramine

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Obesity (AREA)
Diabetes (AREA)
Hematology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Saccharide Compounds (AREA)
Pyrane Compounds (AREA)

ZA847048A 1983-09-10 1984-09-07 6-sulfoxyphenol derivatives,their preparation and their use as cytoprotective agents ZA847048B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE3332780A DE3332780A1 (de)	1983-09-10	1983-09-10	6-sulfoxyphenolderivate, ihre herstellung und ihre verwendung als cytoprotekiva

Publications (1)

Publication Number	Publication Date
ZA847048B true ZA847048B (en)	1985-04-24

Family

ID=6208799

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA847048A ZA847048B (en)	1983-09-10	1984-09-07	6-sulfoxyphenol derivatives,their preparation and their use as cytoprotective agents

Country Status (17)

Country	Link
US (1)	US4661636A (xx)
EP (1)	EP0135860B1 (xx)
JP (1)	JPS6078958A (xx)
KR (1)	KR850002467A (xx)
AT (1)	ATE32714T1 (xx)
AU (1)	AU3283884A (xx)
DE (2)	DE3332780A1 (xx)
DK (1)	DK431684A (xx)
ES (5)	ES535743A0 (xx)
FI (1)	FI843502L (xx)
GR (1)	GR80313B (xx)
HU (1)	HUT37394A (xx)
IL (1)	IL72902A0 (xx)
NO (1)	NO843573L (xx)
PH (1)	PH19713A (xx)
PT (1)	PT79183B (xx)
ZA (1)	ZA847048B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2002501018A (ja)	1998-01-26	2002-01-15	マイトコー	ミトコンドリア関連疾患を処置するためのミトコンドリア保護剤
MXPA04000224A (es)	2001-07-10	2005-07-25	4Sc Ag	Novedosos compuestos como agentes antiinflamatorios, inmunomoduladores y antiproliferativos.
US7122700B2 (en)	2004-07-30	2006-10-17	Xerox Corporation	Arylamine processes
JP4827986B2 (ja) *	2007-06-08	2011-11-30	マンカインドコーポレ−ション	ＩＲＥ−１αインヒビター

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1233969A (xx) *	1969-07-17	1971-06-03
US3804883A (en) *	1970-11-02	1974-04-16	Sandoz Ag	1-(2',4'-disubstituted-6'-omega-substituted-hexyl-1'-phenyl)-1-olefin-3-ones
US3780110A (en) *	1972-02-07	1973-12-18	Olin Corp	Method for preparing 3-fluoro-salicylaldehyde
US3917704A (en) *	1972-03-20	1975-11-04	Smithkline Corp	Alpha-aminoalkyl-4-hydroxy-3-alkylsulfonylmethylbenzyl alcohols
DE2512614C2 (de) *	1974-03-25	1984-02-23	CIBA-GEIGY AG, 4002 Basel	Verfahren zur Herstellung von 4-Hydroxy-3,5-dibrombenzaldehyd
GB1561350A (en) *	1976-11-05	1980-02-20	May & Baker Ltd	Benzamide derivatives
CA1330438C (en) *	1980-07-17	1994-06-28	Willy Meyer	N-phenylsulfonyl-n'-pyrimidinyl-and-triazinylureas
FR2509730A1 (fr) *	1981-07-17	1983-01-21	Carpibem	Nouveaux phenols o-halogenes et o-substitues par un heterocycle, leur procede de preparation, medicaments les contenant, notamment anti-hypertenseurs, et nouveaux intermediaires de synthese

1983
- 1983-09-10 DE DE3332780A patent/DE3332780A1/de not_active Withdrawn
1984
- 1984-09-04 HU HU843327A patent/HUT37394A/hu unknown
- 1984-09-04 AT AT84110509T patent/ATE32714T1/de not_active IP Right Cessation
- 1984-09-04 DE DE8484110509T patent/DE3469522D1/de not_active Expired
- 1984-09-04 EP EP84110509A patent/EP0135860B1/de not_active Expired
- 1984-09-06 FI FI843502A patent/FI843502L/fi not_active Application Discontinuation
- 1984-09-07 PT PT79183A patent/PT79183B/pt unknown
- 1984-09-07 ZA ZA847048A patent/ZA847048B/xx unknown
- 1984-09-07 AU AU32838/84A patent/AU3283884A/en not_active Abandoned
- 1984-09-07 US US06/648,139 patent/US4661636A/en not_active Expired - Fee Related
- 1984-09-07 JP JP59186622A patent/JPS6078958A/ja active Pending
- 1984-09-07 GR GR80313A patent/GR80313B/el unknown
- 1984-09-07 NO NO843573A patent/NO843573L/no unknown
- 1984-09-07 ES ES535743A patent/ES535743A0/es active Granted
- 1984-09-08 KR KR1019840005515A patent/KR850002467A/ko not_active Application Discontinuation
- 1984-09-10 PH PH31195A patent/PH19713A/en unknown
- 1984-09-10 IL IL72902A patent/IL72902A0/xx unknown
- 1984-09-10 DK DK431684A patent/DK431684A/da not_active Application Discontinuation
1985
- 1985-03-05 ES ES540929A patent/ES540929A0/es active Granted
- 1985-03-05 ES ES540927A patent/ES540927A0/es active Granted
- 1985-03-05 ES ES540926A patent/ES540926A0/es active Granted
- 1985-03-05 ES ES540928A patent/ES540928A0/es active Granted

Also Published As

Publication number	Publication date
DE3469522D1 (en)	1988-04-07
PT79183B (de)	1986-09-10
ES8602636A1 (es)	1985-12-01
KR850002467A (ko)	1985-05-13
HUT37394A (en)	1985-12-28
ES8506269A1 (es)	1985-07-01
ES8602638A1 (es)	1985-12-01
GR80313B (en)	1985-01-02
NO843573L (no)	1985-03-11
EP0135860A2 (de)	1985-04-03
AU3283884A (en)	1985-03-14
FI843502A0 (fi)	1984-09-06
EP0135860A3 (en)	1985-10-02
DE3332780A1 (de)	1985-03-28
IL72902A0 (en)	1984-12-31
FI843502L (fi)	1985-03-11
ES8602637A1 (es)	1985-12-01
ES8603691A1 (es)	1985-12-16
ES540927A0 (es)	1985-12-01
US4661636A (en)	1987-04-28
EP0135860B1 (de)	1988-03-02
ES540928A0 (es)	1985-12-01
PH19713A (en)	1986-06-17
ATE32714T1 (de)	1988-03-15
JPS6078958A (ja)	1985-05-04
ES540929A0 (es)	1985-12-01
DK431684D0 (da)	1984-09-10
PT79183A (de)	1984-10-01
ES540926A0 (es)	1985-12-16
ES535743A0 (es)	1985-07-01
DK431684A (da)	1985-03-11

Publication	Publication Date	Title
EP0272110A3 (en)	1989-10-25	Erythromycin a derivatives and method for the preparation of the same
IL74223A0 (en)	1985-05-31	Carbamate compounds,compositions,and methods of making the same
HUT38210A (en)	1986-05-28	Insecticidal, miticidal and nematocidal compositions comprising nitromethylene derivatives as active substance and process for producing the active substances
EG19700A (en)	1995-09-30	Pesticidal 1-arylimidazoles
ES8405398A1 (es)	1984-06-01	Procedimiento para preparar nuevos diazabiciclo-(3.3.1)-nonanos
IL56288A (en)	1985-10-31	15-deoxy-16-hydroxy-2-decarboxy-2-hydroxymethylprostaglandin derivatives and their preparation
GR3018083T3 (en)	1996-02-29	Pesticidal 1-arylimidazoles.
GR852813B (xx)	1986-03-21
ZA847048B (en)	1985-04-24	6-sulfoxyphenol derivatives,their preparation and their use as cytoprotective agents
EP0301433A3 (en)	1990-09-12	Coating resin composition
JPS56131571A (en)	1981-10-15	Novel hetero ring substituted carboxyamide and methyl amine compound
ATE36520T1 (de)	1988-09-15	Polyprenylverbindung, ihre herstellung und pharmazeutische verwendung.
IL69000A (en)	1986-11-30	Organophosphate derivatives,their production and their use as pesticides
EP0281326A3 (en)	1989-10-18	Norbornadiene derivatives
ATE315575T1 (de)	2006-02-15	Immunopotenzierende 5'-nucleotidase-resistente inosinmonophosphat-derivate und ihre verwendung